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dimaprit and Muscle Relaxation

dimaprit has been researched along with Muscle Relaxation in 18 studies

Dimaprit: A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" In order to explore the relationship between H2R and the pathogenesis of bronchial asthma, we investigated the effects of H2R agonist impromidine on guinea-pig isolated tracheal smooth muscle and the effects of dimaprit on the lung function of guinea-pigs provoked by antigen."3.69[The relationship between H2 receptor and the pathogenesis of bronchial asthma in guinea-pigs]. ( Chen, X; Luo, W; Ye, Y, 1995)
" Dose-response curves for adrenaline were carried out as standard protocol."1.31Characteristics of histamine tachyphylaxis in rat uterine smooth muscle. ( Gil Marqués, M; Martínez-Mir, I; Morales-Olivas, FJ; Rubio-Gomis, E, 2002)
"Histamine has a greater relaxant effect on mesenteric artery strips at 22 degrees than at 38 degrees, normally."1.27Dibenamine enhancement of histamine-induced relaxation of the rabbit mesenteric artery. ( Christiansen, VJ; Horst, MA; Robinson, C, 1983)
" The muscarinic antagonist atropine, 1 microM, and the beta 2-adrenoceptor antagonist propranolol, 10 microM, had no effect on the dose-response curve for dimaprit-induced relaxation of the lung strip."1.27A study of the histamine H2-receptor mediating relaxation of the parenchymal lung strip preparation of the guinea-pig. ( Foreman, JC; Rising, TJ; Webber, SE, 1985)
"When dimaprit was compared with 4-methylhistamine, it acted only as a relaxing agent, not as a constricting agent."1.27Participation of vascular H1-receptors in histaminergic relaxation of rabbit middle cerebral artery in vitro. ( Kim, LE; Oudart, N; Sercombe, R; Teste, JF, 1986)
" Pretreatment of parenchymal strips with cimetidine or YM-11170, H2-receptor antagonists, resulted in a parallel shift of the dimaprit dose-response curve to the right."1.26Effects of histamine H2-receptor agonists and antagonists on isolated guinea-pig airway muscles. ( Tomioka, K; Yamada, T, 1982)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's5 (27.78)18.2507
2000's2 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bozarov, A1
Wang, YZ1
Yu, JG1
Wunderlich, J1
Hassanain, HH1
Alhaj, M1
Cooke, HJ1
Grants, I1
Ren, T1
Christofi, FL1
Martínez-Mir, I1
Gil Marqués, M1
Morales-Olivas, FJ1
Rubio-Gomis, E1
Norris, AA1
Eyre, P1
Tomioka, K1
Yamada, T1
Wieczorek, WJ1
D'Mello, A1
Mikkelsen, E1
Sakr, AM1
Jespersen, LT1
Robinson, C1
Christiansen, VJ1
Horst, MA2
Morini, G2
Chiavarini, M1
Bordi, F1
Plazzi, PV1
Vitali, F1
Impicciatore, M1
Robinson, CP1
Chen, X1
Ye, Y1
Luo, W1
Coruzzi, G1
Bertaccini, G1
Ortiz, JL1
Labat, C1
Norel, X1
Gorenne, I1
Verley, J1
Brink, C1
Benedito, S2
Prieto, D2
Nyborg, NC2
Nielsen, PJ1
Tarutani, M1
Sakuma, H1
Shiratsuchi, K1
Mieda, M1
Foreman, JC1
Rising, TJ1
Webber, SE1
Kim, LE1
Teste, JF1
Sercombe, R2
Oudart, N2
Ea Kim, L1

Other Studies

18 other studies available for dimaprit and Muscle Relaxation

ArticleYear
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:6

    Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relation

2009
Characteristics of histamine tachyphylaxis in rat uterine smooth muscle.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:12

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Dru

2002
Impairment of pharmacological modulation of airways smooth muscle by a respiratory pathogen.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:7

    Topics: Airway Resistance; Animals; Bacterial Vaccines; Carbachol; Dimaprit; Haemophilus; Histamine; Isoprot

1981
Effects of histamine H2-receptor agonists and antagonists on isolated guinea-pig airway muscles.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 255, Issue:1

    Topics: Airway Resistance; Animals; Cimetidine; Dimaprit; Drug Interactions; Guinea Pigs; Histamine H2 Antag

1982
Effect of drug-induced tone on the ability of histamine H2 receptor agonists to relax guinea-pig tracheal chain.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:4

    Topics: Animals; Dimaprit; Guanidines; Guinea Pigs; Imidazoles; Impromidine; In Vitro Techniques; Isoprotere

1982
Studies on the effect of histamine in isolated human pulmonary arteries and veins.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:2

    Topics: Aged; Dimaprit; Female; Histamine; Humans; In Vitro Techniques; Male; Methylhistamines; Middle Aged;

1984
Dibenamine enhancement of histamine-induced relaxation of the rabbit mesenteric artery.
    Artery, 1983, Volume: 11, Issue:6

    Topics: Animals; Cold Temperature; Dibenzylchlorethamine; Dimaprit; Drug Synergism; Histamine; Mesenteric Ar

1983
[Imidazolic H2-agonists: importance of 2-amino substitution for pharmacological activity].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Apr-30, Volume: 60, Issue:4

    Topics: Animals; Biological Assay; Cats; Dimaprit; Gastric Acid; Guinea Pigs; Histamine; Methylhistamines; M

1984
Lack of an effect of drugs acting at histamine receptors on norepinephrine-induced relaxation of porcine coronary arteries.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 272, Issue:2

    Topics: Animals; Coronary Vessels; Dimaprit; Histamine; In Vitro Techniques; Muscle Relaxation; Muscle, Smoo

1984
[The relationship between H2 receptor and the pathogenesis of bronchial asthma in guinea-pigs].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1995, Volume: 18, Issue:4

    Topics: Animals; Asthma; Bronchi; Dimaprit; Female; Guinea Pigs; Histamine Agonists; Impromidine; Male; Musc

1995
Contractile and relaxant effects of dimaprit on guinea pig isolated intestinal cells.
    Life sciences, 1997, Volume: 60, Issue:25

    Topics: Animals; Cells, Cultured; Dimaprit; Guinea Pigs; Histamine Agonists; Intestines; Male; Muscle Contra

1997
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Huma

1992
Influence of the endothelium on histamine-induced relaxation of rat middle cerebral arteries in vitro.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Animals; Cerebral Arteries; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Endothelium, Vas

1991
Histamine induces endothelium-dependent relaxation of bovine retinal arteries.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:1

    Topics: Acetylcholine; Animals; Cattle; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Muscle Relax

1991
Histamine H2-receptor antagonistic action of N-(3-[3-(1-piperidinylmethyl)phenoxy]propyl)acetoxyacetamide hydrochloride (TZU-0460).
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:4

    Topics: Animals; Cimetidine; Dimaprit; Dogs; Female; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; His

1985
A study of the histamine H2-receptor mediating relaxation of the parenchymal lung strip preparation of the guinea-pig.
    British journal of pharmacology, 1985, Volume: 86, Issue:2

    Topics: Animals; Atropine; Colforsin; Dimaprit; Female; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle

1985
Participation of vascular H1-receptors in histaminergic relaxation of rabbit middle cerebral artery in vitro.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:2

    Topics: Animals; Cerebral Arteries; Cimetidine; Dimaprit; Drug Interactions; Histamine; In Vitro Techniques;

1986
Relaxation of rabbit middle cerebral arteries in vitro by H1 histaminergic agonists is inhibited by indomethacin and tranylcypromine.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:6

    Topics: Animals; Cerebral Arteries; Dimaprit; In Vitro Techniques; Indomethacin; Male; Methylhistamines; Mus

1988