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dimaprit and Gastric Ulcer

dimaprit has been researched along with Gastric Ulcer in 10 studies

Dimaprit: A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.

Research Excerpts

ExcerptRelevanceReference
" Gastric and duodenal ulcers were induced in the rat by dimaprit (100 mg X kg-1 intravenously) and cysteamine (250 mg X kg-1 subcutaneously), respectively."7.67The effect of the new H2-receptor antagonist mifentidine on gastric secretion, gastric emptying and experimental gastric and duodenal ulcers in the rat: comparison with cimetidine and ranitidine. ( Del Soldato, P; Scarpignato, C; Tangwa, M; Tramacere, R, 1986)
" According to the two dosing schedules adopted to evaluate the duration of action, mifentidine, compared to cimetidine and ranitidine, required considerably lower oral dosages to display its protective effect."5.27Cimetidine, ranitidine and mifentidine in specific gastric and duodenal ulcer models. ( Cereda, E; Del Soldato, P; Donetti, A; Ghiorzi, A, 1985)
"Dimaprit was similarly effective."5.26The involvement of central histamine receptors in stress-induced responses of serum corticosterone and free fatty acids and in gastric ulcer development. ( Bugajski, J; Gadek, A, 1981)
" Gastric and duodenal ulcers were induced in the rat by dimaprit (100 mg X kg-1 intravenously) and cysteamine (250 mg X kg-1 subcutaneously), respectively."3.67The effect of the new H2-receptor antagonist mifentidine on gastric secretion, gastric emptying and experimental gastric and duodenal ulcers in the rat: comparison with cimetidine and ranitidine. ( Del Soldato, P; Scarpignato, C; Tangwa, M; Tramacere, R, 1986)
"Histamine is known to induce gastric ulcers in guinea pigs after intraperitoneal administration and duodenal ulcers after repeated intramuscular administrations."3.66Gastrointestinal ulceration in the guinea pig in response to dimaprit, histamine, and H1- and H2-blocking agents. ( Cho, CH; Pfeiffer, CJ, 1981)
" According to the two dosing schedules adopted to evaluate the duration of action, mifentidine, compared to cimetidine and ranitidine, required considerably lower oral dosages to display its protective effect."1.27Cimetidine, ranitidine and mifentidine in specific gastric and duodenal ulcer models. ( Cereda, E; Del Soldato, P; Donetti, A; Ghiorzi, A, 1985)
"Dimaprit was similarly effective."1.26The involvement of central histamine receptors in stress-induced responses of serum corticosterone and free fatty acids and in gastric ulcer development. ( Bugajski, J; Gadek, A, 1981)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, DC1
Kim, SH1
Choi, BH1
Baek, NI1
Kim, D1
Kim, MJ1
Kim, KT1
Cho, CH1
Pfeiffer, CJ1
Bugajski, J1
Gadek, A1
Del Soldato, P4
DiJoseph, JF2
Wells, CL1
Ghiorzi, A1
Cereda, E1
Donetti, A1
Scarpignato, C1
Tangwa, M1
Tramacere, R1
Eash, JR1
Mir, GN1
Parmar, NS1
Tariq, M1
Ageel, AM1

Other Studies

10 other studies available for dimaprit and Gastric Ulcer

ArticleYear
Curcuma longa extract protects against gastric ulcers by blocking H2 histamine receptors.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:12

    Topics: Acetates; Animals; Anti-Ulcer Agents; Curcuma; Cyclic AMP; Dimaprit; Disease Models, Animal; Dose-Re

2005
Gastrointestinal ulceration in the guinea pig in response to dimaprit, histamine, and H1- and H2-blocking agents.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:4

    Topics: Animals; Cimetidine; Dimaprit; Diphenhydramine; Duodenal Ulcer; Guinea Pigs; Histamine; Histamine H1

1981
The involvement of central histamine receptors in stress-induced responses of serum corticosterone and free fatty acids and in gastric ulcer development.
    Agents and actions, 1981, Volume: 11, Issue:1-2

    Topics: Animals; Brain; Corticosterone; Dimaprit; Fatty Acids, Nonesterified; Histamine H1 Antagonists; Hist

1981
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
    Agents and actions, 1984, Volume: 14, Issue:2

    Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrila

1984
Effect of epidermal growth factor on non-steroidal anti-inflammatory drug-induced intestinal damage.
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dimaprit; Epidermal Growth Factor; Ethanol; Gastri

1989
Cimetidine, ranitidine and mifentidine in specific gastric and duodenal ulcer models.
    Pharmacology, 1985, Volume: 30, Issue:1

    Topics: Animals; Cimetidine; Dimaprit; Disease Models, Animal; Duodenal Ulcer; Female; Guinea Pigs; Histamin

1985
The effect of the new H2-receptor antagonist mifentidine on gastric secretion, gastric emptying and experimental gastric and duodenal ulcers in the rat: comparison with cimetidine and ranitidine.
    Digestion, 1986, Volume: 33, Issue:1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cimetidine; Cysteamine; Dimaprit; Duodenal Ulcer; Femal

1986
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Di

1987
Gastric lesion-preventing or -potentiating activity of clonidine in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Atropine; Clonidine; Dimaprit; Female; Ranitidine; Rats; Rats, Inbred St

1986
Gastric anti-ulcer and cytoprotective effect of selenium in rats.
    Toxicology and applied pharmacology, 1988, Volume: 92, Issue:1

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dimaprit; Ethanol; Female; Gastric Acid; Gastric

1988