Page last updated: 2024-08-23

diltiazem and Injury, Myocardial Reperfusion

diltiazem has been researched along with Injury, Myocardial Reperfusion in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (7.94)	18.7374
1990's	43 (68.25)	18.2507
2000's	10 (15.87)	29.6817
2010's	5 (7.94)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, C; Chen, W; Huang, L; Lu, W; Lv, L; Wu, G; Wu, X; Wu, Y; Xu, N	1
Al-Masri, AA; Almotrefi, AA; Bukhari, IA; Mohamed, OY; Sheikh, SA	1
Chen, C; Chen, W; Ma, Y; Nong, Z; Qiu, S; Wu, G	1
Cao, H; Ke, YS; Shao, ML; Wang, J	1
Inoue, T; Kaneko, N; Matsuda, R; Nishino, S; Oda, K; Otani, N	1
Ando, S; Inoue, K; Itagaki, T; Kashima, T; Shiojiri, Y; Takaba, T	1
Hirota, Y; Iwai, T; Motegi, K; Takeo, S; Tanonaka, K	1
Alhan, C; Kisacikoglu, B; Poyrazoglu, H; Salih, OK; Tokcan, A; Topcuoglu, MS; Ulus, T; Yaliniz, H; Zeren, H	1
Chen, JL; Chen, ZJ; Gao, RL; Jing, ZC; Meng, L; Tian, Y; Wu, YJ; Yang, WX; Yang, YJ; You, SJ; Zhao, JL	1
Kawasumi, H; Kitada, Y; Satoh, N	1
Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A	1
Latour, JG; Provost, P; Rousseau, G	1
Blaise, G; Dumont, L; Garceau, D; Lepage, G; Tanguay, M	1
Kim, HO; Park, YW; Rah, BJ	1
Barrish, JC; Gougoutas, JZ; Grover, G; Hedberg, SA; Malley, MF; Moreland, S; Pudzianowski, AT; Spergel, SH	1
Wu, C	1
Abe, T; Akita, T; Kato, S; Kodama, I; Toyama, J	1
Hutter, JJ; Nearing, BD; Verrier, RL	1
Dzwonczyk, S; Grover, GJ; Monticello, TM	1
Corday, E; Drury, K; Kar, S; Kaul, S; Miyazaki, A; Rydén, L; Satomura, K; Tadokoro, H	1
Daikoku, S; Goto, Y; Haze, K; Itoh, A; Miyazaki, S; Nonogi, H; Saito, K	1
Funakawa, S; Iwaki, K; Masui, M; Matsunaga, K; Mihara, S; Takahara, Y; Uno, O	1
Abiko, Y; Hara, A; Hashizume, H	1
Edenbaum, LR; Gurbel, PA; Herzog, WR; Schlossberg, ML; Serebruany, VL	1
Gurbel, PA; Herzog, WR; Serebruany, VL	1
Buluran, J; Cartier, R; Dagenais, F; Hollmann, C	1
Kuraoka, F; Kuroiwa, A; Murasato, Y; Nagamoto, Y; Nakashima, Y; Urabe, T	1
Obata, T; Yamanaka, Y	1
Gurbel, PA; Herzog, WR; Serebruany, VL; Solomon, SR	1
Matsui, S; Shigenobu, K; Tanaka, H	1
Chin, C; de Guise, P; Grégoire, J; Juneau, M; Pelletier, G; Théroux, P	1
Corretti, MC; Koretsune, Y; Kusuoka, H; Marban, E	1
Kang, Y; Li, P; Wang, GX	1
Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K	1
Kajiwara, H; Kameda, H; Takasaki, A; Takeo, S; Tanonaka, K	1
Becker, BF; Möbert, J	1
Inagaki, K; Izumi, T; Kihara, Y; Sasayama, S	1
Askar, FZ; Bayindir, O; Cevik, A; Demirag, K; Mutaf, I; Ozmen, D; Uyar, M	1
Chierchia, SL; Di Marco, F; Li Volsi, L; Lu, C; Mailhac, A; Margonato, A; Pizzetti, G	1
Nagao, T; Sakamoto, K; Sato, R; Yamazaki, J	1
Hirota, K; Iida, H; Kawarabayashi, T; Maki, N; Omura, T; Sakamoto, K; Takeuchi, K; Yoshikawa, J; Yoshimura, T; Yoshiyama, M	1
Atsumi, N; Hori, M; Ijima, H; Jikuya, T; Matsushita, S; Mitsui, T; Okmamura, K; Sakakibara, Y; Tsutsui, T	1
Kambara, H; Kawai, C; Konishi, J; Nohara, R; Okuda, K; Ono, S; Tamaki, N	1
Ichikawa, H; Kawashima, Y; Koide, A; Komai, H; Nakashima, N; Ohashi, T; Shibata, T; Tanaka, K; Yamamoto, F; Yamamoto, H	1
Haas, M; Punt, NC; van Amsterdam, FT; Zaagsma, J	1
Burckhardt, D	1
Ferrari, R; Visioli, O	1
Calvin, J; Higginson, L; Knoll, G; Tang, A	1
Latour, JG; Merhi, Y; Nattel, S; Rousseau, G; St-Jean, G; Waters, D	1
Bharadwaj, B; Chan, WP; Prasad, K	1
Gazmuri, RJ; Rackow, EC; Ritz, MA; von Planta, M; Weil, MH	1
Abiko, Y; Ichihara, K; Nasa, Y	1
Watts, JA; Zografos, P	1
Galiñanes, M; Hearse, DJ	1
Buja, LM; Eckels, R; Golino, P; Pastor, P; Taylor, AL; Willerson, JT	1
Axford-Gatley, RA; Bush, BG; del Nido, PJ; Mickle, DA; Rebeyka, IM; Romaschin, AD; Wilson, GJ	1
Coetzee, WA; Dennis, SC; Opie, LH; Owen, P; Saman, S	1
Fukamachi, K; Kinoshita, K; Kishizaki, K; Mitani, A; Nakamura, Y; Oe, M; Sakamoto, M; Tokunaga, K; Toshima, Y	1
Klein, HH; Kreuzer, H; Lindert, S; Nebendahl, K; Pich, S; Warneke, G	1
Roberts, R	1
Kanazawa, T; Matsu-Oka, H; Miura, M	1
Ataka, K; Nakamura, K; Nishikawa, Y; Yamamoto, S	1
Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A	1

Reviews

4 review(s) available for diltiazem and Injury, Myocardial Reperfusion

Article	Year
[A new approach to the understanding of the mechanism of ischemia/reperfusion damage in the heart and the effects of anti-ischemic drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1996, Volume: 108, Issue:4 Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Dilazep; Diltiazem; Energy Metabolism; Humans; Lysophosphatidylcholines; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Palmitoylcarnitine; Propranolol; Vasodilator Agents	1996
Diltiazem in ischemia-induced and reperfusion arrhythmias. Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 6 Topics: Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Disease; Coronary Vasospasm; Diltiazem; Myocardial Reperfusion Injury; Platelet Aggregation	1990
Protective effects of calcium antagonists against ischaemia and reperfusion damage. Drugs, 1991, Volume: 42 Suppl 1 Topics: Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Myocardial Reperfusion Injury; Nifedipine; Verapamil	1991
Thrombolysis and its sequelae. Calcium antagonists as potential adjunctive therapy. Circulation, 1989, Volume: 80, Issue:6 Suppl Topics: Animals; Calcium Channel Blockers; Diltiazem; Humans; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Recurrence; Streptokinase; Thrombolytic Therapy; Tissue Plasminogen Activator	1989

Trials

6 trial(s) available for diltiazem and Injury, Myocardial Reperfusion

Article	Year
Effects on reperfusion injury of adding diltiazem to tepid blood cardioplegia. The heart surgery forum, 2004, Volume: 7, Issue:5 Topics: Cardioplegic Solutions; Cardiovascular Agents; Coronary Artery Bypass; Diltiazem; Drug Combinations; Female; Humans; Male; Middle Aged; Myocardial Reperfusion Injury; Temperature; Treatment Outcome	2004
Antiischemic effect of intracoronary diltiazem on myocardial ischemia during PTCA. Heart and vessels, 1996, Volume: 11, Issue:2 Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Diltiazem; Double-Blind Method; Electrocardiography; Female; Humans; Injections, Intra-Arterial; Male; Middle Aged; Myocardial Reperfusion Injury; Time Factors	1996
Intravenous diltiazem in acute myocardial infarction. Diltiazem as adjunctive therapy to activase (DATA) trial. Journal of the American College of Cardiology, 1998, Volume: 32, Issue:3 Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Double-Blind Method; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pilot Projects; Recurrence; Survival Rate; Thrombolytic Therapy; Tissue Plasminogen Activator; Ventricular Function, Left	1998
The protective effects of high dose ascorbic acid and diltiazem on myocardial ischaemia-reperfusion injury. Middle East journal of anaesthesiology, 2001, Volume: 16, Issue:1 Topics: Adult; Aged; Ascorbic Acid; Calcium Channel Blockers; Coronary Artery Bypass; Diltiazem; Female; Hemodynamics; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Postoperative Complications; Prospective Studies; Ventricular Fibrillation	2001
Beneficial effects of diltiazem during myocardial reperfusion: a randomized trial in acute myocardial infarction. Italian heart journal : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:10 Topics: Adult; Aged; Calcium Channel Blockers; Coronary Angiography; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Echocardiography, Stress; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Plasminogen Activators; Risk Factors; Thrombolytic Therapy; Tissue Plasminogen Activator; Ventricular Function, Left	2001
Effect of diltiazem on cardiac function assessed by echocardiography and neurohumoral factors after reperfused myocardial infarction without congestive heart failure. Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:6 Topics: Aged; Blood Pressure; Cardiovascular Agents; Diltiazem; Echocardiography; Epinephrine; Female; Heart; Heart Failure; Heart Function Tests; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Prospective Studies; Time Factors; Ventricular Function, Left	2001

Other Studies

53 other study(ies) available for diltiazem and Injury, Myocardial Reperfusion

Article	Year
Cardioprotective effects of combined therapy with diltiazem and superoxide dismutase on myocardial ischemia-reperfusion injury in rats. Life sciences, 2017, Aug-15, Volume: 183 Topics: Animals; Apoptosis; Calcium; Cardiotonic Agents; Diltiazem; Disease Models, Animal; Drug Therapy, Combination; Female; Gene Expression Regulation; Male; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase	2017
Protective effect of fenofibrate against ischemia-/reperfusion-induced cardiac arrhythmias in isolated rat hearts. Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Diltiazem; Disease Models, Animal; Fenofibrate; Heart Rate; Isolated Heart Preparation; Male; Myocardial Reperfusion Injury; Rats, Wistar; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Premature Complexes	2018
Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:5 Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Combined Modality Therapy; Diltiazem; Disease Models, Animal; Down-Regulation; Endothelin-1; Female; Heart; Hyperbaric Oxygenation; Ischemic Preconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Up-Regulation	2016
[Protective effects of adiponectin on myocardial ischemia-reperfusion injury in rats]. Zhonghua xin xue guan bing za zhi, 2010, Volume: 38, Issue:3 Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Apoptosis; Caspase 3; Diltiazem; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; PPAR gamma; Rats; Rats, Sprague-Dawley	2010
Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem. Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Diltiazem; Isoproterenol; Male; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiazepines	2013
Intracellular calcium increasing at the beginning of reperfusion assists the early recovery of myocardial contractility after diltiazem cardioplegia. The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2003, Volume: 51, Issue:3 Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Heart Arrest, Induced; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Wistar	2003
Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury. Biochemical pharmacology, 2004, Feb-01, Volume: 67, Issue:3 Topics: Animals; Calcium; Cardiotonic Agents; Cardiovascular Agents; Cytochromes c; Diltiazem; Drug Interactions; Ischemia; Male; Mitochondria; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Phosphates; Rats; Rats, Wistar; Reperfusion Injury; Respiration; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchangers	2004
[Beneficial effects of diltiazem on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion]. Zhonghua yi xue za zhi, 2005, Mar-16, Volume: 85, Issue:10 Topics: Animals; Cardiovascular Agents; Diltiazem; Female; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Random Allocation; Swine; Swine, Miniature	2005
Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. Journal of pharmacological sciences, 2007, Volume: 103, Issue:2 Topics: Algorithms; Animals; Benzenesulfonates; Blood Pressure; Calcium; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Piperazines; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger	2007
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart. Cardiovascular research, 1995, Volume: 30, Issue:1 Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea	1995
Sustained myocardial protection by clentiazem (TA-3090) after a 90-minute coronary occlusion and 72 hours of reperfusion in dogs with collateral flow. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Collateral Circulation; Coronary Vessels; Diltiazem; Dogs; Evans Blue; Female; Male; Microspheres; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium	1993
Clentiazem, diltiazem, and cold cardioplegia in isolated ischemic rabbit hearts: relation between additive cardioprotection, physicochemical properties, and preservation of myocardial lipid components. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:6 Topics: Animals; Antihypertensive Agents; Cardioplegic Solutions; Cold Temperature; Coronary Circulation; Diltiazem; Lipid Metabolism; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rabbits	1994
Effect of pretreatment with diltiazem on left ventricular function and intracellular calcium distribution in postischemic reperfused guinea-pig hearts. Coronary artery disease, 1994, Volume: 5, Issue:5 Topics: Animals; Calcium; Creatine Kinase; Diltiazem; Female; Guinea Pigs; Male; Microscopy, Electron; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Perfusion; Premedication; Ventricular Function, Left	1994
Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones. Bioorganic & medicinal chemistry, 1993, Volume: 1, Issue:4 Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Drug Design; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	1993
[The protective effect of different drugs on ischemic-reperfusion injury in experimental pig heart]. Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:3 Topics: Animals; Diltiazem; Female; Male; Myocardial Reperfusion Injury; Myocardium; Swine; Tachycardia, Ventricular; Ventricular Fibrillation; Vitamin E	1993
Protective effects of diltiazem and ryanodine against ischemia-reperfusion injury in neonatal rabbit hearts. The Journal of thoracic and cardiovascular surgery, 1993, Volume: 106, Issue:1 Topics: Animals; Animals, Newborn; Bicarbonates; Blood Pressure; Calcium Chloride; Cardioplegic Solutions; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Hypothermia, Induced; In Vitro Techniques; Magnesium; Microscopy, Electron; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Potassium Chloride; Rabbits; Ryanodine; Sodium Chloride; Ventricular Function, Left	1993
Potent antifibrillatory effect of combined blockade of calcium channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to diltiazem. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Electrocardiography; Female; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Serotonin Antagonists; Verapamil	1996
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts. The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2 Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left	1996
Infarct size reduction with coronary venous retroinfusion of diltiazem in the acute occlusion/reperfusion porcine heart model. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:1 Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Swine	1996
Pharmacological studies on a new antihypertensive agent, S-2150, a benzothiazepine derivative: 1. Antinecrotic and antiarrhythmic effects in reperfused rat hearts. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Creatine Kinase; Diltiazem; Drug Therapy, Combination; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Necrosis; Prazosin; Protein Binding; Rats; Rats, Wistar; Vasodilator Agents	1996
Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine. Pharmacology, 1996, Volume: 53, Issue:4 Topics: Animals; Antithrombin III; Blood Coagulation Factors; Calcium Channel Blockers; Diltiazem; Eicosanoids; Endothelin-1; Female; Fibronectins; Hemodynamics; Magnesium; Myocardial Infarction; Myocardial Reperfusion Injury; Protein C; Protein S; Swine	1996
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor. Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diltiazem; Enzyme-Linked Immunosorbent Assay; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Prostaglandins; Swine; Thromboxane B2	1997
Calcium-channel blockers preserve coronary endothelial reactivity after ischemia-reperfusion. The Annals of thoracic surgery, 1997, Volume: 63, Issue:4 Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Muscle Relaxation; Myocardial Reperfusion Injury; Nifedipine; Rats; Rats, Sprague-Dawley; Verapamil	1997
Effects of lidocaine and diltiazem on recovery of electrophysiologic activity during partial reperfusion following severe myocardial ischemia in canine hearts. Journal of electrocardiology, 1997, Volume: 30, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Infusions, Intravenous; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Tachycardia, Ventricular; Treatment Outcome; Vasodilator Agents	1997
Protective effect of diltiazem on myocardial ischemic injury associated with .OH generation. Comparative biochemistry and physiology. Part A, Physiology, 1997, Volume: 117, Issue:2 Topics: Allopurinol; Animals; Calcium Channel Blockers; Diltiazem; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Norepinephrine; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Xanthine; Xanthine Oxidase; Xanthines	1997
Plasma fibronectin during myocardial ischemia-reperfusion: effects of magnesium, diltiazem, and a novel Mac-1 inhibitor. American journal of hematology, 1998, Volume: 57, Issue:4 Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diltiazem; Female; Fibronectins; Hemodynamics; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Reperfusion Injury; Myocardial Stunning; Swine; Time Factors	1998
Cardioprotective effects of beraprost sodium against experimental ischemia and reperfusion as compared with propranolol and diltiazem. Research communications in molecular pathology and pharmacology, 1998, Volume: 99, Issue:3 Topics: Animals; Diltiazem; Epoprostenol; Guinea Pigs; Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Propranolol; Vasodilator Agents	1998
Mechanism for the cardioprotective effects of the calcium channel blocker clentiazem during ischemia and reperfusion. Japanese circulation journal, 1998, Volume: 62, Issue:8 Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Ferrets; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury	1998
Prophylactic effects of taurine and diltiazem, alone or combined, on reperfusion arrhythmias in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Female; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Superoxide Dismutase; Taurine	1996
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride. Basic research in cardiology, 1998, Volume: 93, Issue:4 Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea	1998
Relationship between myocardial cation content and injury in reperfused rat hearts treated with cation channel blockers. European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cations; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Heart Ventricles; Hypoglycemic Agents; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Nicardipine; Procainamide; Rats; Rats, Wistar; Tetrodotoxin	1999
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3 Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates	1999
The cardioprotective effects of a new 1,4-benzothiazepine derivative, JTV519, on ischemia/reperfusion-induced Ca2+ overload in isolated rat hearts. Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:5 Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fluorometry; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazepines	2000
Differences in protective profiles of diltiazem isomers in ischemic and reperfused guinea pig hearts. European journal of pharmacology, 2002, Jan-11, Volume: 434, Issue:3 Topics: Animals; Atrial Function, Left; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; Isomerism; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Up-Regulation	2002
Effect of stabilized hemoglobin as a component of cardioplegia on warm ischemic heart. Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1992, Volume: 20, Issue:2-4 Topics: Animals; Blood Substitutes; Diltiazem; Heart; Heart Arrest, Induced; Hemodynamics; Hemoglobins; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Oxygen Consumption; Polyethylene Glycols; Rats; Rats, Wistar; Reactive Oxygen Species	1992
Effect of diltiazem on stunned myocardium evaluated with 99mTc-pyrophosphate imaging in canine heart. Japanese circulation journal, 1992, Volume: 56, Issue:3 Topics: Animals; Coronary Disease; Diltiazem; Dogs; Echocardiography; Female; Heart; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Radionuclide Imaging; Technetium Tc 99m Pyrophosphate	1992
Harmful effects of inotropic agents on myocardial protection. The Annals of thoracic surgery, 1991, Volume: 52, Issue:4 Topics: Animals; Body Temperature; Bucladesine; Calcium; Cardiotonic Agents; Creatine Kinase; Diltiazem; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Reperfusion Injury; Pyridones; Rats; Rats, Inbred Strains; Ryanodine	1991
Stereoisomers of calcium antagonists distinguish a myocardial and vascular mode of protection against cardiac ischemic injury. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:2 Topics: Animals; Bepridil; Calcium Channel Blockers; Cardiomyopathies; Coronary Circulation; Coronary Disease; Diltiazem; Gallopamil; Hemodynamics; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Stereoisomerism	1990
Effect of intracoronary diltiazem on infarct size and regional myocardial function in the ischemic reperfused canine heart. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:3 Topics: Animals; Coronary Vessels; Diltiazem; Dogs; Drug Administration Schedule; Infusions, Intra-Arterial; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Time Factors	1991
Diltiazem at reperfusion reduces neutrophil accumulation and infarct size in dogs with ischaemic myocardium. Cardiovascular research, 1991, Volume: 25, Issue:4 Topics: Animals; Collateral Circulation; Coronary Circulation; Diltiazem; Dogs; Female; Heart Rate; Leukocyte Count; Leukocytes; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils	1991
Effects of diltiazem on the functional recovery of the myocardium at organ and cellular level during prolonged hypothermic ischemic cardiac arrest. Angiology, 1990, Volume: 41, Issue:9 Pt 1 Topics: Adenosine Triphosphatases; Animals; Calcium; Cardioplegic Solutions; Creatine Kinase; Diltiazem; Dogs; Female; Heart; Heart Arrest, Induced; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Sarcoplasmic Reticulum	1990
Calcium-entry blockers during porcine cardiopulmonary resuscitation. Clinical science (London, England : 1979), 1990, Volume: 78, Issue:2 Topics: Animals; Blood Pressure; Diltiazem; Disease Models, Animal; Heart Arrest; Hydrogen-Ion Concentration; Myocardial Reperfusion Injury; Resuscitation; Swine; Verapamil	1990
Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2 Topics: Adenosine Triphosphate; Animals; Blood Pressure; Calcium; Coronary Disease; Diltiazem; Fatty Acids, Nonesterified; Heart; Heart Rate; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Stereoisomerism	1990
Shifts in calcium in ischemic and reperfused rat hearts: a cytochemical and morphometric study of the effects of diltiazem. The American journal of cardiovascular pathology, 1990, Volume: 3, Issue:2 Topics: Animals; Calcium; Diltiazem; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Strains	1990
Diltiazem and/or desferrioxamine administered at the time of reperfusion fail to improve post-ischemic recovery in the isolated rat heart after long-term hypothermic storage. Journal of molecular and cellular cardiology, 1990, Volume: 22, Issue:11 Topics: Adenosine Triphosphate; Animals; Cold Temperature; Creatine Kinase; Deferoxamine; Diltiazem; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Organ Preservation; Phosphocreatine; Rats; Rats, Inbred Strains; Ventricular Function, Left	1990
Differential enhancement of postischemic segmental systolic thickening by diltiazem. Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3 Topics: Animals; Coronary Circulation; Diltiazem; Dogs; Female; Hemodynamics; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Systole	1990
Calcium paradox in an in vivo model of multidose cardioplegia and moderate hypothermia. Prevention with diltiazem or trace calcium levels. The Journal of thoracic and cardiovascular surgery, 1990, Volume: 99, Issue:3 Topics: Animals; Blood Pressure; Calcium; Cardiopulmonary Bypass; Coronary Disease; Diltiazem; Dogs; Heart; Heart Arrest, Induced; Hypothermia, Induced; Myocardial Reperfusion Injury; Myocardium; Necrosis	1990
Reperfusion damage: free radicals mediate delayed membrane changes rather than early ventricular arrhythmias. Cardiovascular research, 1990, Volume: 24, Issue:2 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Catalase; Diltiazem; Dose-Response Relationship, Drug; Free Radicals; Guinea Pigs; Heart; Heart Ventricles; Hydrogen Peroxide; In Vitro Techniques; Myocardial Reperfusion Injury; Oxygen; Rats; Superoxide Dismutase; Verapamil	1990
The mechanism of protective effect of diltiazem on reperfusion-induced arrhythmias in isolated rat heart. Japanese circulation journal, 1990, Volume: 54, Issue:1 Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Lactates; Molecular Conformation; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Inbred Strains	1990
Treatment of reperfusion injury with intracoronary calcium channel antagonists and reduced coronary free calcium concentration in regionally ischemic, reperfused porcine hearts. Journal of the American College of Cardiology, 1989, Volume: 13, Issue:6 Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Female; Infusions, Intra-Arterial; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Swine; Verapamil	1989
The protection of the acute ischemic myocardium: merits and demerits of the coronary reperfusion. Japanese circulation journal, 1989, Volume: 53, Issue:9 Topics: Animals; Calcium; Calcium Chloride; Carbon Dioxide; Coronary Disease; Diltiazem; Dobutamine; Dogs; Hydrogen-Ion Concentration; Magnesium; Mitochondria, Heart; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidative Phosphorylation	1989
The protective effects of calcium antagonist and free radical scavenger against myocardial ischemic/reperfusion injury in the isolated rat heart. The Kobe journal of medical sciences, 1989, Volume: 35, Issue:5-6 Topics: Animals; Catalase; Diltiazem; Free Radicals; Heart Rate; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Superoxide Dismutase	1989
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. The Journal of surgical research, 1989, Volume: 47, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Heart Rate; Male; Myocardial Reperfusion Injury; Nifedipine; Rats; Rats, Inbred Strains; Tachycardia; Ventricular Fibrillation; Verapamil	1989