Page last updated: 2024-08-23

diltiazem and Injury, Ischemia-Reperfusion

diltiazem has been researched along with Injury, Ischemia-Reperfusion in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.43)18.7374
1990's18 (51.43)18.2507
2000's9 (25.71)29.6817
2010's4 (11.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaygisiz, O; Ozmerdiven, G; Vuruskan, BA; Vuruskan, H1
Erkalp, K; Inan, B; Küçükgergin, C; Nurten, A; Seçkin, Ş; Sönmez Ergün, S; Zengin Türkmen, A; Ziyade, S1
Borg, J; Charles, AL; Collange, O; Geny, B; Kretz, JG; Levy, F; Oltean, C; Quessard, A; Steib, A; Zeisser, M1
Abu-Risha, SE; El-Sisi, AE; Ibrahim, HA; Sokar, SS1
del Valle, HF; Lascano, EC; Negroni, JA1
Chidlow, G; Melena, J; Osborne, NN; Schmidt, KG; Wood, JP1
Hirota, Y; Iwai, T; Motegi, K; Takeo, S; Tanonaka, K1
Abe, K; Haruna, M; Hirono, S; Ibii, N; Itoh, T; Tokumura, M1
Chin, S; Ikeda, M; Kameoka, S; Ozaki, M1
Alvarez, AI; Mendoza, G; Merino, G; Molina, AJ; Prieto, JG; Pulido, MM; Real, R1
Boachie-Ansah, G; Guc, MO; Kane, KA; Wadsworth, RM1
Albayrak, L; Aydemir, V; Mustafa, NA; Ovali, E; Turgutalp, H; Yandi, M1
Di Giacomo, C; La Delfa, C; Perez-Polo, JR; Renis, M; Russo, A; Sorrenti, V; Vanella, A1
Haverich, A; Karck, M2
Blank, ML; Chaudry, IH; Cobb, LM; Havenstein, PJ; O'Neill, PJ; Steigman, CK; Wilde, RA1
Bertuglia, S; Colantuoni, A; Intaglietta, M1
Baxter, GF; Yellon, DM1
Anderson, GL; Barker, JH; Pemberton, M1
al-Dohayan, AD; al-Tuwaijri, AS1
Edenbaum, LR; Herzog, WR; Schlossberg, ML; Scott, HJ; Serebruany, VL; Vogel, RA1
Kárpáti, E; Lantos, J; Paróczai, M; Röth, E1
Abiko, Y; Chen, M; Hara, A; Hashizume, H; Xiao, CY1
Goto, T; Maeda, K; Ohara, F; Ohkubo, K; Ozaki, T; Seki, J; Sugimoto, T; Yamamoto, N1
Nagao, T; Nishida, M; Sakamoto, K; Urushidani, T1
Fujii, K; Hara, H; Isozaki, H; Nomura, E1
Bernecker, O; Hallström, S; Kröner, A; Mallinger, R; Ploner, M; Podesser, BK; Schirnhofer, J; Seitelberger, R1
Crenesse, D; Cursio, R; Gugenheim, J; Heurteaux, C; Laurens, M; Schmid-Alliana, A; Tornieri, K1
Das, DK; Engelman, RM; Flack, J; Iyengar, J; Kimura, Y; Rousou, J1
Mielke, W; Pethö-Schramm, A; Schmidt, G; Vetterlein, F1
Brunt, RV; Griffiths, EJ1
Ajioka, M; Fukushima, A; Hanaki, Y; Kondo, T; Ozawa, T; Sugiyama, S1
Hayashi, N; Itoh, T; Kawano, S; Ogihara, T; Sakura, H; Sato, N; Tanimura, H; Tsuji, S; Tsujii, M; Yoshihara, H1
Braquet, P; Hosford, D; Koltai, M; Tosaki, A1
Bursch, W; Mühlbacher, F; Rauhs, R; Roth, E; Steininger, R1

Other Studies

35 other study(ies) available for diltiazem and Injury, Ischemia-Reperfusion

ArticleYear
Protective effects of diltiazem and tadalafil on shock wave-induced kidney injury in rats.
    Bratislavske lekarske listy, 2017, Volume: 118, Issue:4

    Topics: Acute Kidney Injury; Animals; Diltiazem; Drug Therapy, Combination; Kidney Glomerulus; Kidney Tubules; Lithotripsy; Male; Nephrectomy; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tadalafil

2017
Effects of Cilostazol and Diltiazem Hydrochloride on Ischemia-Reperfusion Injury in a Rat Hindlimb Model.
    The heart surgery forum, 2017, Apr-29, Volume: 20, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cilostazol; Diltiazem; Disease Models, Animal; Drug Therapy, Combination; Hindlimb; Male; Rats; Rats, Wistar; Reperfusion Injury; Tetrazoles; Treatment Outcome; Vasodilator Agents

2017
Combined intraoperative use of Diltiazem and N-acetylcystein increases myocardial damage and oxidative stress during off-pump cardiac surgery.
    International journal of cardiology, 2013, Oct-03, Volume: 168, Issue:3

    Topics: Acetylcysteine; Calcium Channel Blockers; Coronary Artery Bypass, Off-Pump; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Humans; Intraoperative Care; Oxidative Stress; Reperfusion Injury

2013
Combination of tadalafil and diltiazem attenuates renal ischemia reperfusion-induced acute renal failure in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Creatinine; Diltiazem; Drug Therapy, Combination; Intercellular Adhesion Molecule-1; Interleukin-1beta; Kidney; Male; Malondialdehyde; Peroxidase; Rats; Reperfusion Injury; Superoxide Dismutase; Tadalafil; Tumor Necrosis Factor-alpha

2016
Ischemic shortening of action potential duration as a result of KATP channel opening attenuates myocardial stunning by reducing calcium influx.
    Molecular and cellular biochemistry, 2002, Volume: 236, Issue:1-2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Glyburide; Ischemia; Ischemic Preconditioning, Myocardial; Male; Myocardial Stunning; Pericardium; Potassium Channels; Reperfusion Injury; Sheep; Time Factors

2002
Alpha-lipoic acid protects the retina against ischemia-reperfusion.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Anesthetics, Local; Animals; Antioxidants; Binding, Competitive; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channel Blockers; Cells, Cultured; Ciliary Neurotrophic Factor; Diltiazem; Dizocilpine Maleate; DNA Primers; Dose-Response Relationship, Drug; Drug Interactions; Electroretinography; Fibroblast Growth Factors; Glial Fibrillary Acidic Protein; Glyceraldehyde-3-Phosphate Dehydrogenases; N-Methylaspartate; Nifedipine; Rats; Reperfusion Injury; Retinal Diseases; Reverse Transcriptase Polymerase Chain Reaction; Rhodopsin; RNA, Messenger; Sodium; Tetrodotoxin; Thioctic Acid; Thy-1 Antigens; Veratridine

2002
Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury.
    Biochemical pharmacology, 2004, Feb-01, Volume: 67, Issue:3

    Topics: Animals; Calcium; Cardiotonic Agents; Cardiovascular Agents; Cytochromes c; Diltiazem; Drug Interactions; Ischemia; Male; Mitochondria; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Phosphates; Rats; Rats, Wistar; Reperfusion Injury; Respiration; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchangers

2004
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2004, Volume: 26, Issue:6

    Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertension; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Stroke; Vasodilator Agents; Ventricular Pressure

2004
Protective effect of diltiazem on hepatic ischemia-reperfusion injury in rats by improving liver tissue blood flow.
    Transplantation proceedings, 2005, Volume: 37, Issue:10

    Topics: Animals; Blood Flow Velocity; Diltiazem; Disease Models, Animal; Liver; Liver Circulation; Male; Rats; Rats, Wistar; Reperfusion Injury; Vasodilator Agents

2005
Effects of ischemia-reperfusion on the absorption and esterase metabolism of diltiazem in rat intestine.
    Life sciences, 2007, Jan-09, Volume: 80, Issue:5

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Esterases; Inactivation, Metabolic; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes; Rats; Rats, Wistar; Reperfusion Injury

2007
Comparison of antiarrhythmic and electrophysiologic effects of diltiazem and its analogue siratiazem.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Diltiazem; Electric Stimulation; Electrophysiology; Heart; Hemodynamics; Male; Purkinje Fibers; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sheep

1993
Role of diltiazem in ischemia-reperfusion injury of the intestine.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1994, Volume: 26, Issue:6

    Topics: Animals; Calcium; Diltiazem; Infusions, Intravenous; Intestine, Small; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1994
Lipid peroxidation and survival in rats following cerebral post-ischaemic reperfusion: effect of drugs with different molecular mechanisms.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:5

    Topics: Allopurinol; Animals; Antioxidants; Brain Ischemia; Deferoxamine; Diltiazem; Lipid Peroxidation; Male; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Verapamil; Vitamin E

1994
Role of calcium channel blockers in postischemic lungs.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Animals; Diltiazem; Hemodynamics; Lung; Nifedipine; Rabbits; Reperfusion Injury; Water-Electrolyte Balance

1994
Reperfusion injury following testicular torsion and detorsion in prepubertal rats.
    Urological research, 1993, Volume: 21, Issue:6

    Topics: Animals; Deferoxamine; Diltiazem; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium Chloride; Spermatic Cord Torsion; Time Factors

1993
Effect of leukocyte adhesion and microvascular permeability on capillary perfusion during ischemia-reperfusion injury in hamster cheek pouch.
    International journal of microcirculation, clinical and experimental, 1993, Volume: 13, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Capillary Permeability; Cell Adhesion; Cheek; Cricetinae; Diltiazem; Leukocytes; Male; Mesocricetus; Perfusion; Pyrazoles; Reperfusion Injury; Verapamil

1993
Attenuation of reperfusion-induced ventricular fibrillation in the rat isolated hypertrophied heart by preischemic diltiazem treatment.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Diltiazem; Disease Models, Animal; Heart; Heart Rate; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Premedication; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ventricular Fibrillation

1993
Characterization of microvascular vasoconstriction following ischemia/reperfusion in skeletal muscle using videomicroscopy.
    Microsurgery, 1996, Volume: 17, Issue:1

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Diltiazem; Endothelium; Male; Mice; Microcirculation; Microscopy, Video; Muscles; Nitroprusside; Reperfusion Injury; Superoxide Dismutase; Vasoconstriction; Vasodilator Agents

1996
The potential synergistic effect of calcium channel blockers and alpha-tocopherol on gastric mucosal injury induced by ischaemia-reperfusion.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:11

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; Injections, Intraperitoneal; Male; Nifedipine; Rats; Rats, Wistar; Reperfusion Injury; Verapamil; Vitamin E; Wound Healing

1996
Short-term low dose intracoronary diltiazem administered at the onset of reperfusion reduces myocardial infarct size.
    International journal of cardiology, 1997, Volume: 59, Issue:1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Myocardial Infarction; Reperfusion Injury; Swine

1997
The effects of bisaramil and antiarrhythmics on free radical generation of isolated neutrophil granulocytes.
    Acta chirurgica Hungarica, 1997, Volume: 36, Issue:1-4

    Topics: Animals; Anti-Arrhythmia Agents; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Carcinogens; Cell Membrane; Chlorobenzenes; Diltiazem; Dogs; Dose-Response Relationship, Drug; Free Radicals; Mexiletine; Neutrophils; Reperfusion Injury; Superoxides; Tetradecanoylphorbol Acetate

1997
Palmitoyl-L-carnitine modifies the myocardial levels of high-energy phosphates and free fatty acids.
    Basic research in cardiology, 1997, Volume: 92, Issue:5

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Creatine Kinase; Diltiazem; Fatty Acids, Nonesterified; Heart; Male; Myocardial Contraction; Myocardium; Palmitoylcarnitine; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spectrophotometry

1997
Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:4

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzyl Alcohol; Benzyl Alcohols; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Hemodynamics; In Vitro Techniques; Ion Transport; Lidocaine; Lymphocytes; Male; Myocardial Infarction; Myocardial Ischemia; Propionates; Propranolol; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; Time Factors; Ventricular Fibrillation

1999
Treatment with l-cis diltiazem before reperfusion reduces infarct size in the ischemic rabbit heart in vivo.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:4

    Topics: Anesthesia; Animals; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Heart; Hemodynamics; Isomerism; Male; Myocardial Infarction; Myocardial Ischemia; Rabbits; Reperfusion Injury; Time Factors

1999
Calcium concentration in hepatocytes during liver ischaemia-reperfusion injury and the effects of diltiazem and citrate on perfused rat liver.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Citric Acid; Diltiazem; Liver; Male; Mitochondria, Liver; Rats; Rats, Wistar; Reperfusion Injury

2000
Diltiazem during reperfusion preserves high energy phosphates by protection of mitochondrial integrity.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2002, Volume: 21, Issue:2

    Topics: Adenine Nucleotides; Analysis of Variance; Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Diltiazem; Disease Models, Animal; Female; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Phosphocreatine; Probability; Rabbits; Random Allocation; Reference Values; Reperfusion Injury; Sensitivity and Specificity

2002
Diltiazem reduces apoptosis in rat hepatocytes subjected to warm hypoxia-reoxygenation.
    Pharmacology, 2002, Volume: 65, Issue:2

    Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Enzyme Activation; Hepatocytes; Hot Temperature; Hypoxia; Liver; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Oxygen; Rats; Rats, Wistar; Reperfusion Injury

2002
Moderation of myocardial ischemia reperfusion injury by calcium channel and calmodulin receptor inhibition.
    Heart and vessels, 1992, Volume: 7, Issue:4

    Topics: Animals; Calcium Channels; Calmodulin-Binding Proteins; Coronary Circulation; Creatine Kinase; Diltiazem; Female; Male; Malondialdehyde; Models, Cardiovascular; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Oxygen Consumption; Reperfusion Injury; Swine; Trifluoperazine

1992
Nifedipine and diltiazem reduce pulmonary edema formation during postischemic reperfusion of the rabbit lung.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:2

    Topics: Animals; Diltiazem; Hemodynamics; Lung Transplantation; Nifedipine; Pulmonary Edema; Rabbits; Reperfusion Injury

1992
Effects of diltiazem and allopurinol in postischemic microcirculatory changes in the rat kidney.
    International journal of microcirculation, clinical and experimental, 1991, Volume: 10, Issue:2

    Topics: Allopurinol; Animals; Capillaries; Capillary Permeability; Diltiazem; Drug Interactions; Erythrocyte Aggregation; Globulins; Kidney; Male; Microcirculation; Rats; Rats, Inbred Strains; Regional Blood Flow; Reperfusion Injury; Time Factors

1991
The effect of calcium antagonists on the activities of lipid metabolizing enzymes in the isolated ischaemically perfused and reperfused rat heart.
    Journal of molecular and cellular cardiology, 1990, Volume: 22, Issue:3

    Topics: Acyltransferases; Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Glycerol-3-Phosphate O-Acyltransferase; Heart; Lipase; Lipid Metabolism; Male; Myocardium; Nifedipine; Rats; Rats, Inbred Strains; Reperfusion Injury; Verapamil

1990
Acceleration of recovery of mitochondrial function after coronary reperfusion by various coronary dilating drugs in canine hearts.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Dilazep; Diltiazem; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mitochondria, Heart; Monoamine Oxidase Inhibitors; Niacinamide; Nicorandil; Reperfusion Injury; Vasodilator Agents

1989
Changes in the intracellular calcium ion concentration in the gastric mucosa in a rat ischemia-reperfusion model.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Animals; Calcium; Diltiazem; Gastric Mucosa; Intracellular Membranes; Ions; Male; Osmolar Concentration; Phosphorylase a; Rats; Rats, Inbred Strains; Reperfusion Injury

1989
Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion.
    European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Diltiazem; Diterpenes; Ginkgolides; Heart Function Tests; Lactones; Male; Metoprolol; Myocardial Reperfusion; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reperfusion Injury

1989
Protective effect of PGI2 and diltiazem on liver ischemia and reperfusion in pigs.
    Transplantation proceedings, 1988, Volume: 20, Issue:5

    Topics: Ammonia; Animals; Blood Flow Velocity; Body Water; Diltiazem; Epoprostenol; Indocyanine Green; Ischemia; Liver; Reperfusion Injury; Swine

1988