diltiazem has been researched along with Hypoxia in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (39.39) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aaronson, PI; Becker, S; Kizub, IV; Prieto-Lloret, J; Shaifta, Y; Snetkov, VA; Soloviev, AI; Strielkov, IV; Ward, JP | 1 |
| Deng, W; Farricielli, L | 1 |
| Li, J; Li, M; Liu, X; Meng, G | 1 |
| Amano, A; Kurihara, H; Matsushita, S; Okada, T; Sakai, T; Watanabe, M | 1 |
| Jernigan, NL; Resta, TC; Walker, BR | 1 |
| Curtis, TM; de Gooyer, TE; Gardiner, TA; Humphries, P; Simpson, DA; Stevenson, KA; Stitt, AW | 1 |
| Chesler, E; Lundquist, LJ; Weir, EK; Young, TE | 1 |
| Henry, PD; Wahl, AM | 1 |
| Ashraf, M; Rahamathulla, PM | 1 |
| Ashraf, M; Benedict, J; Rahamathulla, PM; Schwartz, A | 1 |
| Payne, RS; Rigor, BM; Schurr, A | 1 |
| Brooks, KJ; Kauppinen, RA | 1 |
| du Souich, P; Hartemann, D; Saunier, C | 1 |
| Nagao, T; Vanhoutte, PM | 1 |
| Clarke, W; Cohen, AH; Fouty, B; Hanson, K; McMurty, IF; Morris, K; Rodman, DM | 1 |
| Aaronson, PI; Hague, D; Robertson, TP; Ward, JP | 1 |
| Crenesse, D; Cursio, R; Gugenheim, J; Heurteaux, C; Laurens, M; Schmid-Alliana, A; Tornieri, K | 1 |
| Gu, LM; Xiao, Y; Yuan, F; Zhou, ZN | 1 |
| Liang, D; Thurman, RG | 1 |
| Hashimoto, H; Hirano, M; Konishi, K; Utsunomiya, H | 1 |
| Briggs-Tung, C; Cartee, GD; Holloszy, JO | 1 |
| Katsumata, Y; Mori, S; Murakami, K; Yamamoto, C; Yoshino, M | 1 |
| Abiko, Y; Hara, A; Matsumura, H | 1 |
| Ishida, Y; Paul, RJ | 1 |
| Katusic, ZS; Vanhoutte, PM | 1 |
| Reeves, WC; Schildt, N; Whitesell, L; Wood, MA | 1 |
| Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS | 1 |
| Fukao, N; Fukumoto, T; Takeo, S; Tanaka, T; Tanonaka, K; Tazuma, Y; Yoshikawa, C | 1 |
| Cartheuser, CF | 1 |
| Escoubet, B; Griffaton, G; Lechat, P; Samuel, JL | 1 |
| Battistella, P; Breda, JL; Clozel, JP; Delorme, N; Polu, JM | 1 |
| Packer, M | 1 |
| Chappell, SP; Henderson, AH; Lewis, MJ | 1 |
1 review(s) available for diltiazem and Hypoxia
| Article | Year |
|---|---|
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Lung Diseases, Obstructive; Nifedipine; Rats; Vasoconstriction; Verapamil | 1985 |
1 trial(s) available for diltiazem and Hypoxia
| Article | Year |
|---|---|
Hemodynamic effects of intravenous diltiazem in hypoxic pulmonary hypertension.
Topics: Blood Gas Analysis; Diltiazem; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstructive; Male; Middle Aged; Oxygen; Oxygen Consumption; Random Allocation | 1987 |
31 other study(ies) available for diltiazem and Hypoxia
| Article | Year |
|---|---|
Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Gap Junctions; Glycyrrhetinic Acid; Hypoxia; Male; Phosphorylation; Protein Phosphatase 1; Pulmonary Artery; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2013 |
Hypoxic hepatitis and acute liver failure in a patient with newly onset atrial fibrillation and diltiazem infusion.
Topics: Acute Kidney Injury; Aged; Atrial Fibrillation; Diltiazem; Hepatitis; Humans; Hypotension; Hypoxia; Liver Diseases; Liver Failure, Acute; Male; Thrombocytopenia; Vasodilator Agents | 2013 |
Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.
Topics: Angiotensin II; Animals; Apoptosis; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytoprotection; Diltiazem; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Hypoxia; Male; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Vascular Diseases | 2015 |
Inhibition of connexin43 dephosphorylation is involved in protective effects of diltiazem on cardiac function during hypoxic injury.
Topics: Animals; Blotting, Western; Cardiotonic Agents; Connexin 43; Connexins; Diltiazem; Fluorescent Antibody Technique; Heart; Hemodynamics; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; Perfusion; Phosphorylation; Rats; Rats, Wistar | 2011 |
Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia.
Topics: Animals; Diltiazem; Endothelin-1; Hypoxia; Kinetics; Male; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spermine; Vasodilation | 2004 |
Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.
Topics: Animals; Apyrase; Cyclic Nucleotide Phosphodiesterases, Type 6; Dark Adaptation; Diltiazem; Enzyme-Linked Immunosorbent Assay; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Light; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitroimidazoles; Oxygen Consumption; Phosphoric Diester Hydrolases; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Rhodopsin; RNA, Messenger; Transcriptional Activation; Vascular Endothelial Growth Factor A | 2006 |
Comparative effects of nifedipine, verapamil, and diltiazem on experimental pulmonary hypertension.
Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Prostaglandins F; Pulmonary Wedge Pressure; Pyridines; Vascular Resistance; Verapamil | 1983 |
Diltiazem and nitrendipine suppress hypoxic contracture in quiescent ventricular myocardium.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rabbits | 1983 |
Cardiac injury in short duration anoxia and modification by diltiazem, a calcium channel blocking agent.
Topics: Animals; Benzazepines; Calcium; Cardiomyopathies; Diltiazem; Hypoxia; Male; Mitochondria, Heart; Myocardium; Rats; Rats, Inbred Strains | 1984 |
Effects of diltiazem on anoxic injury in the isolated rat heart.
Topics: Aerobiosis; Animals; Benzazepines; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Heart; Hypoxia; Male; Mitochondria, Heart; Myocardium; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains | 1983 |
Synergism between diltiazem and MK-801 but not APV in protecting hippocampal slices against hypoxic damage.
Topics: Animals; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Hypoxia; Kinetics; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley | 1995 |
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Effect of acute and chronic moderate hypoxia on diltiazem kinetics and metabolism in the dog.
Topics: Acute Disease; Animals; Chronic Disease; Diltiazem; Dogs; Hypoxia; Male | 1993 |
Electrical and mechanical changes during anoxic contractions of the isolated canine basilar artery.
Topics: Animals; Basilar Artery; Calcium; Diltiazem; Dogs; Electrophysiology; Female; Hypoxia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Potassium; Vasoconstriction | 1993 |
Inhibition of cyclic 3'-5'-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; Perfusion; Phosphodiesterase Inhibitors; Piperidines; Pulmonary Circulation; Purinones; Quinazolines; Rats; Rats, Sprague-Dawley; Vasodilation | 1996 |
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; Dinucleoside Phosphates; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Hypoxia; Imidazoles; In Vitro Techniques; Ion Channel Gating; Lanthanum; Male; Membrane Potentials; Nifedipine; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Vasoconstriction; Verapamil | 2000 |
Diltiazem reduces apoptosis in rat hepatocytes subjected to warm hypoxia-reoxygenation.
Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Enzyme Activation; Hepatocytes; Hot Temperature; Hypoxia; Liver; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Oxygen; Rats; Rats, Wistar; Reperfusion Injury | 2002 |
[Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Hemodynamics; Hypoxia; Male; Nifedipine; Ventricular Function; Verapamil | 1992 |
Protective effects of the calcium antagonists diltiazem and TA3090 against hepatic injury due to hypoxia.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Hypoxia; Ischemia; L-Lactate Dehydrogenase; Liver; Liver Diseases; Oxygen; Rats; Rats, Sprague-Dawley; Trypan Blue | 1992 |
[The effects of calcium antagonists on ventilation-perfusion mismatching in the canine lung].
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Hypoxia; Models, Biological; Nifedipine; Oxygen; Partial Pressure; Pulmonary Artery; Pulmonary Gas Exchange; Vasoconstriction; Ventilation-Perfusion Ratio; Verapamil | 1992 |
Diverse effects of calcium channel blockers on skeletal muscle glucose transport.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Glucose; Hypoxia; Male; Methylglucosides; Muscles; Nifedipine; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil | 1992 |
Effect of Ca2(+)-entry blocker on the stimulation of aerobic metabolism in rats acclimatized to high altitude hypoxia.
Topics: Adaptation, Physiological; Aerobiosis; Altitude; Animals; Calcium; Diltiazem; Hypoxia; Ketone Bodies; Lactates; Male; Rats; Rats, Inbred Strains; Uric Acid | 1991 |
Effect of diltiazem on the oxymyoglobin level of myocardial cells in the isolated, perfused rat heart during hypoxia.
Topics: Animals; Diltiazem; Heart; Hypoxia; Male; Myocardium; Myoglobin; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Ventricular Function, Left | 1990 |
Effects of hypoxia on high-energy phosphagen content, energy metabolism and isometric force in guinea-pig taenia caeci.
Topics: Adenine Nucleotides; Aerobiosis; Animals; Calcium; Carbachol; Diltiazem; Energy Metabolism; Guinea Pigs; Histamine; Hypoxia; Isometric Contraction; Lactates; Lactic Acid; Male; Muscle, Smooth; Oxygen Consumption; Phosphocreatine; Potassium | 1990 |
Anoxic contractions in isolated canine cerebral arteries: contribution of endothelium-derived factors, metabolites of arachidonic acid, and calcium entry.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cerebral Arteries; Cyclooxygenase Inhibitors; Diltiazem; Dinoprost; Dogs; Endothelium; Female; Hypoxia; Male; Potassium; Prostaglandins F; Serotonin; Uridine Triphosphate; Vasoconstriction | 1986 |
Effect of diltiazem and ibuprofen on right ventricular hypertrophy in an experimental model of hypoxic pulmonary hypertension.
Topics: Animals; Benzazepines; Cardiomegaly; Diltiazem; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Imidazoles; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains | 1985 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dogs; Female; Hypoxia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Serotonin; Verapamil | 1986 |
Diltiazem and verapamil reduce the loss of adenine nucleotide metabolites from hypoxic hearts.
Topics: Adenine Nucleotides; Adenosine; Animals; Body Water; Calcium; Creatine Kinase; Diltiazem; Female; Heart; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Kinetics; Male; Myocardial Contraction; Myocardium; Perfusion; Rabbits; Reference Values; Verapamil | 1988 |
Slow channel inhibitor effects on brain function: tolerance to severe hypoxia in the rat.
Topics: Animals; Bencyclane; Bepridil; Brain; Calcium Channel Blockers; Cinnarizine; Diltiazem; Electroencephalography; Fendiline; Flunarizine; Gallopamil; Heart Rate; Hypoxia; Nimodipine; Prenylamine; Pyrrolidines; Rats; Rats, Inbred Strains; Respiration; Verapamil | 1988 |
Calcium antagonists stimulate prostaglandin synthesis by cultured rat cardiac myocytes and prevent the effects of hypoxia.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cells, Cultured; Cobalt; Diltiazem; Dinoprostone; Epoprostenol; Fibroblasts; Glycogen; Heart; Hypoxia; Myocardium; Prostaglandins E; Pyrrolidines; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Myocardial reoxygenation damage: can it be circumvented?
Topics: Animals; Calcium; Cats; Diltiazem; Heart; Hypoxia; In Vitro Techniques; Lidoflazine; Myocardial Contraction; Myocardium; Ouabain; Oxygen; Papillary Muscles; Perfusion; Rabbits; Stimulation, Chemical; Verapamil | 1985 |