diltiazem has been researched along with Hypertension in 538 studies
*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 200 (37.17) | 18.7374 |
| 1990's | 235 (43.68) | 18.2507 |
| 2000's | 78 (14.50) | 29.6817 |
| 2010's | 21 (3.90) | 24.3611 |
| 2020's | 4 (0.74) | 2.80 |
| Authors | Studies |
|---|---|
| Das, J; Duff, KJ; Floyd, DM; Kimball, SD; Krapcho, J; Lago, MW; Lee, VG; Moquin, RV; Turk, CF; White, RE | 1 |
| Das, J; Duff, KJ; Floyd, DM; Gougoutas, JZ; Kimball, SD; Lago, MW; Lee, VG; Malley, MF; Moquin, RV; Vu, TC | 1 |
| Barrett, RJ; Johnson, CP; Proakis, AG; Shanklin, JR | 1 |
| Fujiwara, I; Hatano, N; Honda, Y; Kurokawa, M; Mastumoto, J; Naruto, S; Sato, F; Uno, H; Yoshida, T | 1 |
| Almond, HR; Brannan, MD; Carmosin, RJ; Carson, JR; Flaim, SF; Gill, A; Gleason, MM; Keely, SL; Ludovici, DW; Pitis, PM | 1 |
| Peng, DF; Peng, X; Tang, SY | 1 |
| Ko, CJ; Siegel, JD | 1 |
| Sardesai, M; Shende, P | 1 |
| Hong, SJ; Kim, JS; Kook, H; Lee, S; Park, CG; Yang, KS | 1 |
| Chossegros, C; Foletti, JM; Hadj Saïd, M; Stroumsa, R | 1 |
| Hou, F; Li, Q; Li, W; Liu, J; Shi, Q; Wang, W | 1 |
| Bae, S; Chaplin, DJ; Kang, PM; Ke, Q; Samad, MA | 1 |
| De Keulenaer, GW; De Meyer, GR; Fransen, P; Leloup, AJ; Schrijvers, DM; Van Hove, CE | 1 |
| Punkla, W; Raksamani, K; Rushatamukayanunt, P; Sakaew, A; Sirivanasandha, B; Sutthivaiyakit, K; Waitayawinyu, P | 1 |
| Borlak, J; Zwadlo, C | 1 |
| Bertera, FM; Höcht, C; Mayer, MA; Opezzo, JA; Taira, CA | 1 |
| Ezeugo, U; Glasser, SP | 1 |
| Lee, R | 1 |
| Bajuszova, Z; Klimas, J; Krenek, P; Kyselovic, J; Ochodnicky, P; Vaja, V | 1 |
| Barcik, K; Flis, E; Placek, W; Protas-Drozd, F; Weiss-Rostkowska, W | 1 |
| Fujii, M; Fujisawa, H; Ideguchi, M; Ishihara, H; Kajiwara, K; Kato, S; Suzuki, M; Yoshikawa, K | 1 |
| Brown, NJ; Fong, P; Pretorius, M; Stafforini, DM | 1 |
| Eckel, RH | 1 |
| Itokawa, H; Kato, A; Michio, F; Moriya, M; Nakashima, K; Noda, M; Ogura, Y; Oishi, A; Okamoto, N | 1 |
| Almgren, P; Dahlberg, J; Fava, C; Hedner, T; Kjeldsen, S; Melander, O; Svensson-Färbom, P; Wahlstrand, B | 1 |
| Díez, J | 1 |
| Hu, M; Mak, VW; Tomlinson, B | 1 |
| Isabelle, M; Ragonnet, C; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
| Jaka, A; Lobo, C; López-Núñez, M; López-Pestaña, A; Ormaechea, N; Tuneu, A | 1 |
| Barrios, V | 1 |
| Chen, CC; Dahly-Vernon, AJ; Dunn, KM; Ledbetter, SR; Murphy, SR; Roman, RJ; Williams, JM | 1 |
| Blaszczyk, AT; Vouri, SM | 1 |
| Drożdż, J; Filipiak, KJ; Grajek, S; Kasprzak, JD; Opolski, G; Rynkiewicz, A; Stępińska, J; Tykarski, A; Wożakowska Kapłon, B | 1 |
| Agodoa, LY; Appel, LJ; Bakris, GL; Charleston, J; Contreras, G; Gabbai, F; Greene, T; Hiremath, L; Jamerson, K; Kendrick, C; Kusek, JW; Lash, JP; Lea, J; Miller, ER; Phillips, RA; Rahman, M; Rostand, S; Toto, R; Wang, X; Wright, JT | 1 |
| Gadzhiev, AN | 1 |
| Kritz, H; Oguogho, A; Sinzinger, H; Wolfram, RM | 1 |
| Mazerkina, IA; Pavlova, LI; Svetyĭ, LI | 1 |
| Albert, KS; Gana, TJ; Glasser, SP; Neutel, JM | 1 |
| Leenen, FH; Ruzicka, M | 1 |
| Hansson, L; Hedner, T; Kjeldsen, SE; Lund-Johansen, P; Syvertsen, JO | 1 |
| Amar, J; Joire, JE; Salvador, M | 1 |
| Carré, A; Joire, JE; Lequeuche, B; Mounier-Vehier, C | 1 |
| White, WB | 1 |
| Chen, BX; Chen, JZ; Fan, WH; Liu, XJ; Yao, XY; Zhu, JH | 1 |
| Hirota, K; Ishihara, H; Kabara, S; Kitayama, M; Kushikata, T; Matsuki, A | 1 |
| Aronow, WS; Frishman, WH | 1 |
| Boyer, M; Katta, R; Markus, R | 1 |
| Aggeli, C; Economou, E; Pitsavos, C; Stefanadis, C; Toutouza, M; Toutouzas, P; Tsioufis, K; Vasiliadou, K; Zervoudaki, A | 1 |
| Halkin, A; Hochenberg, M; Ish-Shalom, M; Justo, D; Rosso, R; Viskin, S; Zeltser, D | 1 |
| Bernheim, J; Green, J; Hasdan, G; Korzets, Z; Podjarny, E; Rashid, G | 1 |
| Pujol, MD; Romero, M; Sánchez, I | 1 |
| Albert, KS; Bohannon, K; Gana, TJ; Pascual, LG; Sica, DA; Wright, JT | 1 |
| Albert, KS; Gana, T; Lacourciere, Y; Pascual, MG; Smith, DH; White, WB | 1 |
| Kothari, J; Nash, M; Ramesh Prasad, GV; Zaltzman, J | 1 |
| Hayashi, H; Ishizaki, T; Kosuge, K; Nishio, S; Ohashi, K; Satoh, H; Uchida, S; Watanabe, H; Yamada, H | 1 |
| Abe, K; Haruna, M; Hirono, S; Ibii, N; Itoh, T; Tokumura, M | 1 |
| Handler, J | 1 |
| Sica, D | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Marhuenda, E; Márquez-Martín, A; Pérez-Guerrero, C | 1 |
| Claas, SA; Glasser, SP | 1 |
| Aberg, JA; Fichtenbaum, CJ; Gerber, JG; Glesby, MJ; Grosskopf, N; Hafner, R; Hall, S; Kendall, MA; Zolopa, AR | 1 |
| Carrera, MJ; Micaló, T; Montanya, E; Pérez-Maraver, M; Sahun, M; Soler, J; Vinzia, C | 1 |
| Głuszek, J; Kara-Perz, H; Kosicka, T; Perz, S | 1 |
| Karotsis, AK; Mastorantonakis, SE; Stergiou, GS; Symeonidis, A | 1 |
| Casanova, A; Fitchett, DH; Goodman, SG; Jaffer, S; Kornilova, O; Langer, A; Tan, M | 1 |
| Nykamp, D; Winter, EE | 1 |
| Akritidis, N; Katsanou, A; Koutsouka, F; Pappas, G; Petrakis, D; Raptis, L | 1 |
| Emura, K; Moriwaki, M; Toyoshi, T; Yokomizo, A | 1 |
| Geerts, R; Hunter, K; Pylypchuk, G; Raymond, N; Tobe, SW | 1 |
| Ang, PS; Su, DH; Tow, SL | 1 |
| Almgren, P; Färbom, P; Hedner, T; Kjeldsen, S; Lanke, J; Melander, O; Skrtic, S; Wahlstrand, B; Weiss, L | 1 |
| Scordo, KA; Stone, KS | 1 |
| Hirsch, AT; Inouye, IK; Massie, BM; Tubau, JF | 1 |
| MacAlpin, R | 1 |
| Ellrodt, AG; Singh, BN | 1 |
| Bühler, FR | 1 |
| Abe, H; Fukushima, M; Hamanaka, Y; Inoue, M; Maeda, T; Matsumoto, M; Matsuyama, T; Nakajima, S; Shimazu, T; Yasui, K | 1 |
| Henry, PD | 1 |
| Horwitz, DL | 1 |
| Ewy, GA | 1 |
| Karlsberg, RP | 1 |
| Johnston, WE; Lowenstein, E | 1 |
| Ambrose, JE | 1 |
| Covinsky, JO; Hamburger, SC | 1 |
| D'Agostino, F; Tullio, D; Valerio, A | 1 |
| Frishman, WH; Ocken, S; Spivack, C | 1 |
| Heidbreder, E; Heidland, A; Hörl, WH; Schäfer, RM | 1 |
| Aoki, K; Kondo, S; Sato, K; Yamamoto, M | 1 |
| Benowitz, N; Inouye, IK; Loge, D; Massie, BM; Simpson, P | 1 |
| Klein, WW | 1 |
| Ban, M; Ito, T; Kobayashi, T; Ogawa, K; Suzuki, Y; Watanabe, T; Yamazaki, N | 1 |
| Hess, DS; Scheinman, MM | 1 |
| Beer, N; Charlap, S; Frishman, WH; Kimmel, B; Peled, HB; Weinberg, P | 1 |
| Brandt, D | 1 |
| Antman, EM; Rossi, LP | 1 |
| Fujiwara, K; Horie, R; Kamino, K; Kihara, M; Mano, M; Nara, Y; Tagami, M; Yamori, Y | 1 |
| Nagao, T; Narita, H; Yabana, H; Yamaguchi, I | 1 |
| Kondo, S; Nakano, T; Noziri, A; Oonishi, N; Takezawa, H; Yamakado, T | 1 |
| Inouye, IK; Loge, D; Massie, BM; Simpson, P; Tubau, JF | 1 |
| Heidbreder, E; Heidland, A; Hörl, WH; Schäfer, R | 1 |
| Chlewicka, I; Wasowska, T | 1 |
| Achimastos, A; Levenson, J; Safar, M; Simon, A; Temmar, M | 1 |
| Benetos, AM; Bouthier, JE; Levenson, JA; Safar, ME; Simon, AC | 1 |
| Dipalma, JR | 1 |
| Cazor, JL; Levenson, JA; Safar, ME; Simon, AC | 1 |
| Brandt, D; Härringer, M; Klein, W; Vrecko, K | 1 |
| Zaret, GM | 1 |
| Cauvin, C; Pegram, B | 1 |
| Howes, LG; Hutchinson, JS; Takata, Y | 1 |
| Sawai, K | 1 |
| Hutchinson, JS; Takata, Y | 1 |
| Eichelbaum, M | 1 |
| Ito, K; Kanazawa, T; Morita, T; Nose, T | 1 |
| Kiyomoto, A; Nagao, T; Nakajima, H; Narita, H; Sato, M | 1 |
| Bohl, E | 1 |
| Bassett, AL; Ezrin, AM; Fitterman, WS; Myerburg, RJ; Wong, SS | 1 |
| Maeda, K; Shiota, K; Takasugi, T; Tanaka, Y; Tsukano, Y | 1 |
| Nayler, WG | 1 |
| Fleckenstein, A; Fleckenstein-Grün, G | 1 |
| Fujii, Y; Saitoh, Y; Tanaka, H; Toyooka, H | 1 |
| Dabsys, SM; Delorenzi, A; Finkielman, S; Garcia, SI; Martinez, VN; Nahmod, VE; Pirola, CJ; Santajuliana, D | 1 |
| Kokkinos, P; Narayan, P; Papademetriou, V | 1 |
| Dakshinamurti, K; Lal, KJ | 1 |
| Iwasaki, H; Kikkawa, K; Kurosawa, H; Murata, S; Nagao, T; Toriumi, W | 1 |
| Hagihara, T; Kishi, Y; Matsumoto, G; Matsuo, H; Naka, K; Nanjo, K; Ohoshi, T; Sanke, T; Sasaki, H; Sowa, R | 1 |
| Dohi, Y; Kojima, M; Sato, K | 1 |
| Hafner, K; Meeves, S; Park, G; Weber, M | 1 |
| Ollivier, JP; Stalla-Bourdillon, A; Wajman, A | 1 |
| Weir, MR | 1 |
| Baptista, A; Rocha, E; Serra-Pinto, L | 1 |
| Garde, E; Jørgensen, HS; Lassen, NA; Olsen, TS | 1 |
| Iimura, O; Kudoh, Y; Kuroda, S; Shimamoto, K | 1 |
| Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K | 1 |
| Baleynaud, S; Cohen-Solal, A; Gourgon, R; Laperche, T; Sebag, C | 1 |
| Casiglia, E; Dorigatti, F; Graniero, GR; Lotoro, F; Palatini, P; Pessina, AC; Vriz, O | 1 |
| Almkvist, H; Berglund, L; Björnsson, T; Fagher, B; Henningsen, N; Honkavaara, M; Naukkarinen, V; Nordenström, P; Sillanpää, J; Thulin, T | 1 |
| Hill, GE; Hurlbert, BJ; Munro, J | 1 |
| Nobre, F; Oigman, W | 1 |
| Ferner, RE; Lip, GY | 1 |
| de Haan, HP; Lie, KI; May, JF; Saleh, AE; van Boven, AJ; van Gilst, WH | 1 |
| Gabbasov, ZA; Parfenova, EV; Popov, EG; Sharipova, GKh; Vikhert, OA | 1 |
| Burford, RG; Lacourcière, Y; Lefebvre, J; Poirier, L | 1 |
| Amery, A; Bulpitt, CJ; Coope, J; Evans, JG; Fletcher, AE; Lightowlers, S; O'Malley, K; Palmer, A; Potter, J; Sever, P | 1 |
| Biscione, F; Lanza, GA; Manzoli, A; Natale, A; Santarelli, P | 1 |
| Chrysant, SG; Miller, E | 1 |
| Czirfuzs, A; Fleckenstein-Grün, G; Frey, M; Matyas, S; Thimm, F | 1 |
| Khapaev, BA; Ol'binskaia, LI; Vartanova, OA | 1 |
| Hirayama, T; Kano, T; Katayama, Y; Tsubokawa, T | 1 |
| Anzalone, D; Chrysant, S; Fagan, T; Flamenbaum, W; Kaihlanen, PM; Lueg, M; Weir, MR | 1 |
| Johansson, CG; Lind, L; Lithell, H; Ljunghall, S; Mörlin, C | 1 |
| Belgrave, GP; Hosie, J; Nasar, MA; Walters, EG | 1 |
| Lahiri, A; Raftery, EB; Sridhara, BS; Thomas, P | 1 |
| Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE | 1 |
| Chen, SX; Gong, LS; Gu, TH; Guo, JZ; Song, DJ; Wang, XM | 1 |
| Deckert, J; Gleiter, CH; Przuntek, H | 1 |
| Bernard-Fernier, MF; de La Garoullaye, A; Gosse, P; Zannad, F | 1 |
| Meeves, SG; Park, GD | 1 |
| Abe, T; Kawahito, S; Kimura, H; Kitahata, H; Kohyama, A; Saito, T | 1 |
| Bernard-Fernier, MF; Mallion, JM; Poggi, L; Renucci, JF; Siche, JP; Vaisse, B | 1 |
| Neumann, HA; Sanders, CJ | 1 |
| Schreiber, RT; Schuna, AA; Steele, RM | 1 |
| Hamer, HP; Havinga, TK; Lie, KI; May, JF; Schuurman, FH; Smit, AJ; ten Berge, BS; van der Veur, E; van Leeuwen, JT; Wesseling, H | 1 |
| Akhadov, ShV; Belousov, IuB; Volkov, MG | 1 |
| Messerli, FH; Weiner, DA | 1 |
| Bartels, DW; Bauman, JL; Kondos, GT; Labreche, DG | 1 |
| Goldstein, M; Masuyama, Y; Tsuda, K; Tsuda, S | 1 |
| Hashimoto, H; Kanda, A | 1 |
| Amado, P; Araújo, V; Carmona, J; Castanheira, J; Nazaré, J | 1 |
| Glotov, MN; Mazur, NA; Pshenitsin, AI | 1 |
| Hohnloser, SH; Just, H; Klingenheben, T; Zabel, M | 1 |
| Abadi, AH; Beaudreau, CA; Lopez, LM; Rutledge, DR | 1 |
| Cardella, CJ; Leenen, FH; Legault, L; Ogilvie, RI | 1 |
| Frishman, WH | 1 |
| Paulshock, BZ | 1 |
| Fukuya, F; Honda, Y; Hosoki, K; Ikeno, A; Karasawa, T; Kataoka, T; Minato, H; Nose, I; Takeyama, K; Yamada, T | 1 |
| Barouki, F; el Fertak, L; Lévy, BI; Pieddeloup, C; Safar, ME | 1 |
| Lund-Johansen, P; Omvik, P | 2 |
| Applegate, WB | 1 |
| Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H | 1 |
| Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ | 1 |
| Francis, DM; Fullinfaw, R; Higgins, TJ; King, GN; Walker, RG; Wiesenfeld, D | 1 |
| Pfaffendorf, M; van Zwieten, PA | 1 |
| Boulet, AP; Chockalingam, A; Handa, SP; Ruddy, TD; Savard, D; Wright, JM | 1 |
| Bernheim, J; Green, J; Haskiah, A; Podjarny, E; Pomeranz, A; Rathaus, M | 1 |
| Blackshear, JL; Hammill, SC; Kopecky, SL; Litin, SC; Safford, RE | 1 |
| Hamer, HP; Havinga, TK; Lie, KI; May, JF; Schuurman, FH; Smit, AJ; ten Berge, BS; van der Veru, E; van Leeuwen, JT; Wesseling, H | 1 |
| Bourge, R; Brozena, SC; Clemson, B; Hobbs, R; Johnson, MR; Miller, L; Mills, RM; Naftel, D; Olivari, MT; Quigg, R; Ventura, H | 1 |
| Horwhat, JD; Landry, FJ; Pinski, L; Tomich, D | 1 |
| Black, HR; Brown, TE; Carter, BL; Elliott, WJ; Saseen, JJ | 1 |
| Applegate, WB; Cohen, JD; Davis, A; Green, S; Wolfson, P | 1 |
| Afonso, LC; Bedford-Rice, K; Raman, BB; Sowers, JR; Standley, PR | 1 |
| Bianchi, C; Caputo, M; Donadio, C; Giordani, R; Lucchetti, A; Silvestri, L; Tramonti, G | 1 |
| Levy, R; Nagauker-Shriker, O; Schlaeffer, F | 1 |
| Cachofeiro, V; Casal, MC; Lahera, V; Maeso, R; Navarro-Cid, J; Perez-Vizcaino, F; Ruilope, LM; Tamargo, J | 1 |
| Hedner, T; Lindholm, LH; Nilsson, P | 1 |
| Boulet, AP; Chockalingam, A; Fischer, L; Handa, SP; Ruddy, TD; Savard, D; Wright, JM | 1 |
| Stewart, WH | 1 |
| Joy, A; Manning, G; Mathias, CJ; McDonald, CJ; Millar-Craig, MW | 1 |
| Funayama, M; Kubo, N; Kuroda, K; Kuwata, N; Ogawa, A; Sato, N | 1 |
| Furukawa, H; Iwaki, K; Iwasaki, T; Kawakami, M; Matsumura, S; Matsunaga, K; Shimamura, T; Yonetani, Y | 1 |
| Schiffrin, EL; Touyz, RM | 1 |
| Adrogue, HJ; Goldstein, R; Hricik, DE; Levine, BS; Weinberg, MS | 1 |
| Araújo, D; Cabezas-Cerrato, J; Garcia-Estevez, DA; Iglesias, M | 1 |
| Mion Júnior, D; Ortega, KC; Santello, JL | 1 |
| Boulet, AP; Tessier, G | 1 |
| Ijiri, H; Ishihara, T; Ishii, H; Iwasaki, H; Kohno, I; Komori, S; Mochizuki, Y; Mukaiyama, S; Okutani, M; Sano, S; Satoh, Y; Tamura, K | 1 |
| Cases, M; Closas, J; Coca, A; de la Sierra, A; Esqúe, J; Mínguez, A; Módol, J; Palos, MA; Plana, J; Sobrino, J; Soler, J | 1 |
| Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Funayama, M; Kuroda, K; Kuwata, N; Ogawa, A; Sato, N; Suzuki, M; Taguchi, S; Takahashi, A; Yabuta, A | 1 |
| Boulet, AP; Chockalingam, A; Fodor, JG; Langer, A; Nadeau, C; Rakusan, K; Savard, D | 1 |
| Chrysant, SG; Jain, A; Korrin, I; Massie, BM; Weir, M; Weiss, R | 1 |
| Cappuccio, FP; MacGregor, GA | 1 |
| Demetris, AJ; Gritsch, A; Jordan, M; Katari, SR; Magnone, M; McCauley, J; Randhawa, PS; Scantlebury, V; Shapiro, R; Starzl, T; Vivas, C | 1 |
| Dan, K; Horie, T; Katori, K; Kubo, N; Ohara, G | 1 |
| Chan, P; Lee, YS; Lin, CN; Lin, TH; Tomlinson, B | 1 |
| Bareiss, P; Germain, P; Koegler, A; Plan, D; Roul, G | 1 |
| Albrecht, FE; Asico, LD; Eisner, GM; Jose, PA | 1 |
| Takahashi, K; Takahashi, T; Tanikawa, S | 1 |
| Kobrin, I; Lacourcière, Y; Massie, BM; Viskoper, R; Woittiez, A | 1 |
| Dernellis, J; Pitsavos, C; Stefanadis, C; Toutouzas, K; Toutouzas, P; Tsiamis, E; Tsioufis, C; Vlachopoulos, C | 1 |
| Geshi, E; Katagiri, T; Konno, N; Watanabe, T; Yanagishita, T | 1 |
| Boileau, G; Bolli, P; Handa, SP; Larochelle, P; Leenen, FH; Myers, M; Tanner, J; Wilson, TW | 1 |
| Pitt, B | 1 |
| Clegg, L; Horwitz, LD; Weinberger, HD | 1 |
| Grossman, E; Messerli, FH | 1 |
| Kobashigawa, JA | 1 |
| Igata, Y; Ikeda, S; Maekawa, T; Shiraishi, M; Watanabe, T; Yamamoto, S | 1 |
| Amah, G; Ben Mais, H; Blacher, J; Girerd, X; Kheder, A; London, GM; Safar, ME | 1 |
| Ijiri, H; Kohno, I; Okutani, M; Tamura, K | 1 |
| Kobrin, I | 1 |
| Cohen, JD; Cushman, WC; Jones, RP; Marbury, TC; Rhoades, RB; Smith, LK | 1 |
| Conlin, PR; Williams, GH | 1 |
| Chrysant, SG; Gavras, H; Goldstein, R; Marbury, TC; Niederman, AL | 1 |
| Watts, RW; Wing, LM | 1 |
| Schwartzkopff, B; Strauer, BE | 1 |
| Fujii, Y; Kihara, S; Takahashi, S; Tanaka, H; Toyooka, H | 1 |
| Bernadet-Monrozies, P; Poilleux, E; Suc, JM | 1 |
| Fujii, Y; Saitoh, Y; Takahashi, S; Toyooka, H | 2 |
| Buckley, SJ; Feng, JD; Yeung, PK | 1 |
| Costa, A; García-Guasch, R; Llubià, C; Preciado, MJ; Sust, M; Vidal, F | 1 |
| Berglund, E; Dahlöf, C; Engqvist, L; Lagerstedt, C; Lehtonen, A; Nilsson-Ehle, P; Thulin, T | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ | 1 |
| Reilly, MC; Zbrozek, AS | 1 |
| Antunes, E; de Luca, IM; de Nucci, G; de Oliveira, CF; Metze, K; Moreno, H; Nathan, LP; Sucupira, M; Zappellini, A; Zatz, R | 1 |
| Chern, MS; Lin, FC; Wu, D | 1 |
| Hatta, T; Itoh, H; Kawa, T; Kiyama, M; Miki, S; Moriguchi, J; Morimoto, S; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K | 1 |
| Neutel, JM; Smith, DH; Weber, MA | 1 |
| Barta, J; Kovács, T; Nagy, J; Szelestei, T | 1 |
| Smith, KM | 1 |
| Pool, PE | 1 |
| Dernellis, J; Diamantopoulos, L; Michaelides, A; Stefanadis, C; Toutouzas, P; Tsiamis, E | 1 |
| Bhandari, S; Saxena, GN; Sharma, P; Swarup, D; Tuteja, R | 1 |
| Hedner, T | 1 |
| Kinoshita, Y; Masuyama, Y; Nishio, I; Tsuda, K | 1 |
| Beach, CL; Ford, DE; Klag, MJ; Mead, LA; Roht, LH | 1 |
| Kawano, Y; Makino, Y; Okuda, N; Omae, T; Takishita, S | 1 |
| Fassotte, CE; Huberlant, BC; Leeman, MJ; Lins, RL; Sternon, JE | 1 |
| Dahlöf, B; de Faire, U; Hansson, L; Hedner, T; Karlberg, BE; Kjeldsen, SE; Lanke, J; Lindholm, LH; Lund-Johansen, P; Syvertsen, JO | 2 |
| Cusson, J; Lamarre-Cliche, M; Lambert, R; Larochelle, P; Van Nguyen, P; Wistaff, R | 1 |
| Beckey, NP; Korman, L; Parra, D | 1 |
| Luca, S; Terranova, R | 1 |
| Dorbaeva, DE; Teĭblium, MM; Zaslavskaia, RM | 2 |
| Adelman, A | 1 |
| Achard, JM; Aldigier, JC; Oudart, N | 1 |
| Avanzini, F; Tognoni, G | 1 |
| Bouffandeau, B; Fournier, A; Georgita, A; Oprisiu, R | 1 |
| Kjeldsen, SE; Os, I; Westheim, AS | 1 |
| Boden, WE; Eschwege, E; Lauret, D; Scheldewaert, R; Vray, M | 1 |
| Prisant, LM | 1 |
| Inui, S; Itami, S; Yoshikawa, K | 1 |
| Imanaga, K; Inoue, T; Ogawa, R; Ogura, A; Shiga, T; Wajima, Z; Yoshikawa, T | 1 |
| de Paula, RS; Gebara, O; Gruppi, C; Moffa, P; Nussbacher, A; Pereira-Barreto, AC; Pierri, H; Pinto, L; Serro-Azul, JB; Wajngarten, M | 1 |
| Fujimura, A; Maeda, A; Sasaki, M | 1 |
| Boden, WE; Gibson, RS; Hansen, JF; Messerli, FH; Schechtman, KB | 1 |
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| Ruddy, MC | 1 |
| Benchetrit, S; Bernheim, J; Green, J; Katz, B; Podjarny, E | 1 |
| Feely, J; Hennessy, M; Mahmud, A | 1 |
| Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Ichihara, K; Kaneta, S; Marumo, H; Satoh, K; Yamamoto, A | 1 |
| Hansson, L; Hildebrandt, PR; Kjeldsen, SE; Lund-Johansen, P; Tuxen, CD | 1 |
| Duggan, JA; Tabrizchi, R | 1 |
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| Beliaev, SD; Khetagurova, LG; Zaslavskaia, RM | 1 |
| Fagard, R; Staessen, JA; Thijs, L; Wang, J | 1 |
| Ikeo, T; Ikezawa, K; Murata, S; Narita, H; Sato, M; Yamaguchi, I | 1 |
| Fujibayashi, Y; Hashida, J; Hatano, M; Kajiwara, N; Kita, T; Kobayashi, Y; Murakami, A; Ono, M; Osada, T; Satoh, Y; Shimoda, K; Tei, T; Uchiyama, T; Yamamoto, Y | 1 |
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| Horiguchi, M; Kuriyama, S; Nakamura, K; Sakai, O; Uchida, H | 1 |
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| Amodeo, C | 1 |
| Eferakeya, AE; Osunkwo, UA | 1 |
| Banno, K; Iwasaki, H; Kikkawa, K; Murata, S; Nagao, T; Toriumi, W | 1 |
| Eff, J; Magner, DJ; Whelton, A | 1 |
| Grossman, E; Maoz, E; Rosenthal, T; Thaler, M | 1 |
| Lemmer, B; Mattes, A; Witte, K | 1 |
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| Frohlich, ED; Isshiki, T; Kardon, MB; Nishikimi, T; Uchino, K | 1 |
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| Bühler, FR; Kiowski, W; Linder, L | 2 |
| Carcone, B; Claudel, S; Elkik, F; Grippon, P | 2 |
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| Boer, P; Folkers, HB; Geyskes, GG; Kleinbloesem, CH; van Zwienen, JC | 1 |
| Arenoso, HJ; Godoy, J; Soutric, JL; Yasky, J | 1 |
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| Akella, J; Cho, S; Factor, SM; Fein, FS; Malhotra, A; Sonnenblick, EH; vanHoeven, KH | 1 |
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| Brown, M; Carleen, E; Eberly, S; McDermott, M; Moss, AJ; Oakes, D; Rubison, M | 1 |
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| Applegate, WB; Koch, GG; Luhr, JC; Park, GD; Phillips, HL; Schnaper, H; Schocken, D; Shepherd, AM | 1 |
| Coupez, JM; Coupez-Lopinot, R; Dupont, AG; Hermanns, P; Jensen, P; Nicolas, M; Schoors, DF | 1 |
| Binder, EF; Birge, SJ; Cayabyab, L; Ritchie, DJ | 1 |
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| Ishihara, H; Kimura, F; Koh, H; Kushikata, T; Matsuki, A; Satoh, T | 1 |
| Abraham, AS; Barchilon, E; Brooks, BA; Eylath, U; Grafstein, Y; Nubani, N; Shemesh, O | 1 |
| Deuter, G; Kapoor, SC; Krishna, GG; Narins, RG; Riley, LJ | 1 |
| Bune, AJ; Cain, MD; Chalmers, J; Morris, MJ; Russell, AE; Tonkin, AL; West, MJ; Wing, LM | 1 |
| Boylan, JF; Ivanov, J; Mickle, DA; O'Leary, G; Teasdale, SJ; Weisel, RD | 1 |
| Coulter, DM | 1 |
| Busse, JC; de Velasco, RE; Pellegrini, EL | 1 |
| Hirota, Y; Ishikawa, H; Ishikawa, K; Kagoshima, T; Katori, R; Kawakita, S; Kinoshita, M | 1 |
| Pedrinelli, R; Salvetti, A | 1 |
| Lechner, W; Margreiter, R; Steurer, W | 1 |
| Heikkinen, J; Inkovaara, J; Nikkilä, M | 1 |
| Gustafsson, S; Hedner, T; Olsson, SO; Thulin, T | 2 |
| Nappi, JM; Pool, PE; Weber, MA | 1 |
| Griffin, B; Ramanathan, KB; Ratts, TE; Sullivan, JM | 1 |
| Cristol, JP; Jover, B; Mimran, A; Ribstein, J; Valentin, JP | 1 |
| Haneda, T; Obata, H; Tanaka, H | 1 |
| Haywood, LJ | 1 |
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| Buckley, MM; Goa, KL; Grant, SM; McTavish, D; Sorkin, EM | 1 |
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| Myburgh, DP | 1 |
| Davis, WR; DiPette, DJ; Evans, RR; Holland, OB; Wallace, JM | 1 |
| Masuyama, Y; Nishio, I; Shima, H; Tsuda, K | 1 |
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| Ahmad, S | 1 |
| Bernheim, J; Kariv, N; Podjarny, E; Pomeranz, A; Rathaus, M; Shapira, J; Zadok, S | 1 |
| Chalmers, J; Taylor, S; Wing, L | 1 |
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| Bauer, JH; Reams, GP | 2 |
| Boucher, S; Lacourcière, Y; Poirier, L; Spenard, J | 2 |
| Jones, AW; Smith, JM | 1 |
| Effron, MB; Kelemen, MH; Stewart, KJ; Valenti, SA | 1 |
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| Burris, JF; Cady, WJ; Oparil, S; Stewart, WH; Weber, M; Weir, MR | 1 |
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| Brouwer, RM; Bühler, FR; Follath, F | 1 |
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| Aoki, K; Asano, M; Matsuda, T | 1 |
| Gadgil, UG; Khalil-Manesh, F; Samant, DR; Venkataraman, K | 1 |
| Blackshear, JL; Garnic, D; Harrington, DP; Hollenberg, NK; Williams, GH | 1 |
| Swartz, SL | 1 |
| Takahashi, H; Yoshimura, M | 1 |
| Nara, Y; Note, S; Sato, T; Yamori, Y | 1 |
| Goering, JL; Raich, PC; Zimmerman, BG | 1 |
| Covinsky, JO; Park, GD; Stallard, MP; Stewart, WH; Waller, ES | 1 |
| DesChamps, MK; Gray, J; Heusner, JJ; Hollifield, JW | 1 |
| Dustan, HP | 1 |
| Weiss, RJ | 1 |
| Bianco, G; Cellamare, G; Poppa, E; Sgobba, G | 1 |
| Auch-Schwelk, W; Katusic, ZS; Vanhoutte, PM | 1 |
| Gonzales, A; Kawanishi, DT; O'Rourke, RA; Rahimtoola, SH; Reid, CL | 1 |
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| Wang, L | 1 |
| Massie, BM; Szlachcic, J; Tubau, JF; Vollmer, C | 1 |
| Piepho, RW; Sowers, JR | 1 |
| Chellingsworth, MC; Kendall, MJ; Pasi, J; Singh, BM; Wright, AD | 1 |
| Dipette, DJ; Evans, RR; Herron, JM; Nappi, JM; Pool, PE; Reeves, RL; Rosenblatt, S; Staker, LV | 2 |
| Ivleva, AIa; Krasnobaeva, GM; Lepakhin, VK; Moiseev, VS; Ogoliuk, LIu | 1 |
| Hvarfner, A; Lithell, H; Ljunghall, S; Mörlin, C; Pollare, T; Präntare, H | 1 |
| Gaĭdamakina, NE; Gavrilova, EN; Ivleva, AIa; Krasnobaeva, GM; Shatkovskiĭ, NP | 1 |
| Wallis, DE | 1 |
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| Chern, MS; Cherng, WJ; Hung, JS; Wu, JJ | 1 |
| Heikkinen, JT; Inkovaara, JA; Nikkilä, MT; Olsson, SO | 1 |
| Abernethy, DR; Montamat, SC | 3 |
| Kohvakka, A; Luurila, OJ; Sundberg, S | 1 |
| Masuyama, Y; Nishio, I; Tsuda, K | 1 |
| Alitto, F; Corso, S; Loison, M; Maragno, I; Neri, G; Sandri, R; Santostasi, G | 1 |
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| Zicha, J | 1 |
| Slagle, DA | 1 |
| Bidiville, J; Brunner, HR; Nussberger, J; Porchet, M; Waeber, B; Waeber, G | 2 |
| Kido, R; Masuyama, Y; Minatogawa, Y; Nishio, I; Shima, H; Tsuda, K; Tsuda, S; Yoshikawa, H | 1 |
| Kuchii, M; Masuyama, Y; Nishio, I; Tsuda, K | 1 |
| McGoon, MD; Shub, C; Vlietstra, RE | 1 |
| Massie, BM | 1 |
| Kuznetsov, VN | 1 |
| Kawanishi, DT; Leman, RB; O'Rourke, RA; Pratt, CM | 1 |
| Frohlich, ED | 2 |
| Bauer, JH; Reams, G; Sunderrajan, S | 3 |
| Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H | 1 |
| Bent, B; Weiss, RJ | 1 |
| Henderson, S; Massie, BM; Parmley, WW; Sievers, R; Szlachcic, J; Tubau, JF; Wikman-Coffelt, J | 1 |
| Kohno, M; Kurihara, N; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Moser, M | 1 |
| Akimoto, Y; Kikkawa, K; Murata, S; Nagao, T; Narita, H; Sugawara, Y; Yabana, H | 1 |
| Abernethy, D; DiPette, DJ; Wolfson, P; Zusman, R | 1 |
| Raich, PC; Zimmerman, BG | 1 |
| Hartman, E; Leehey, DJ | 1 |
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| Muiesan, G | 1 |
| Frohlich, ED; Isshiki, T; Pegram, BL | 2 |
| Amodeo, C; Frohlich, ED; Isshiki, T; Messerli, FH; Pegram, BL | 1 |
| Andrén, L; Dotevall, A; Eggertsen, R; Höglund, P; Olson, SO; Svensson, A; Wadenvik, H | 1 |
| Corvol, P; Jeunemaitre, X; Julien, J; Pagny, JY; Plouin, PF | 1 |
| Mir, AK; Petty, MA | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 1 |
| Ginsberg, D; Gutgsell, TL; Karp, R; Pappas, JE; Rofman, BA; Schumer, B; Walker, SD | 1 |
| Busse, JC; Materson, BJ | 1 |
| DesChamps, M; Dickson, B; Gray, J; Heusner, JJ; Hollifield, JW; Peace, KE; Spyker, DA | 1 |
| Birnbaum, PL; Ivanov, J; Laidley, DT; Liu, P; Madonik, MM; Miller, DR; Mullen, JC; Teasdale, SJ; Teoh, KH; Weisel, RD | 1 |
| Anderson, M; Bartels, D; Eidelson, BA; Labreche, DG; MacCarthy, EP; Massie, B; Ramanathan, KB; Tubau, JF; Ulep, D; Weiss, RJ | 1 |
| Gröhn, P; Hämäläinen, L; Härkönen, R; Heikkilä, J; Idänpään-Heikkilä, U; Kohvakka, A; Luurila, OJ; Rytkönen, U; Setälä, M; Sundberg, S | 1 |
| Arigoni, C; Beretta-Piccoli, C; Pusterla, CE; Rusca, A | 1 |
| Gordon, NF; Myburgh, DP | 1 |
| Giard, MJ; Josselson, J; Lam, YW; Posner, JN; Saunders, E; Warren, JB; Weir, MR; Zaske, DE | 1 |
| Bauer, JH; Lau, A; Messina, C; Reams, GP; Villarreal, D | 1 |
| Cheung, DG; Graettinger, WF; Lipson, JL; Weber, MA | 1 |
| Leary, WP; van der Byl, K | 1 |
| Horie, R; Kihara, M; Mori, C; Nishio, T; Watanabe, K; Yamori, Y | 1 |
| Belton, ED; Carryon, P; Harper, B; Mason, T; Olaya, PI | 1 |
| Cenarruzabeitia, E; Fos, D; Isanta, JR; Lasheras, B | 2 |
| Burgess, CD | 1 |
| Ijichi, H; Ikegaki, I; Iyoda, I; Matsuzawa, M; Okabayashi, H; Suga, K; Takahashi, H; Yoshimura, M | 1 |
| Aoki, K; Fujimoto, S; Matsuda, T | 1 |
| Dang Tran, L; Gaillard, G; Montastruc, JL; Montastruc, P; Valet, P | 1 |
| Amodeo, C; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO | 1 |
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| Gaw, J; Hirsch, AT; Massie, BM; Pool, PE; Salel, AF; Samant, DR; Seagren, SC; Tubau, JF; Venkataraman, K | 1 |
| Hamann, SR; McAllister, RG; Schloemer, GL | 1 |
| Charlap, S; Frishman, WH; Goldberger, J; Kimmel, B; Klein, N; Phillippides, G | 1 |
| Furui, H; Sotobata, I; Taniguchi, N; Yamauchi, K | 1 |
| Larach, DR; Zelis, R | 1 |
| Becker, A; Beldzik, A; Gasińska, T; Prochaczek, F | 1 |
| Charlap, S; Frishman, WH; Michelson, EL | 1 |
| Kendall, MJ; Okopski, JV | 1 |
| Magyar, P; Miskovits, G; Zsamboki, G | 1 |
| Frishman, WH; Kirkendall, W; Lunn, J; McCarron, D; Moser, M; Schnaper, H; Smith, LK; Sowers, J; Swartz, SL; Zawada, ET | 1 |
| Klein, MD; Weiner, DA | 1 |
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| Ishimori, K; Kanayama, Y; Kohno, M; Matuura, T; Morishima, I; Murakawa, K; Takeda, T; Yasunari, K; Yonezawa, T | 1 |
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77 review(s) available for diltiazem and Hypertension
| Article | Year |
|---|---|
Calcium channel blockers and risk of breast cancer: a meta-analysis of 17 observational studies.
Topics: Adult; Aged; Antihypertensive Agents; Breast Neoplasms; Calcium Channel Blockers; Case-Control Studies; Cohort Studies; Diltiazem; Female; Humans; Hypertension; Middle Aged; Nifedipine; Odds Ratio | 2014 |
Clinical benefits versus shortcomings of diltiazem once-daily in the chronotherapy of cardiovascular diseases.
Topics: Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Delayed-Action Preparations; Diltiazem; Drug Chronotherapy; Humans; Hypertension; Risk Assessment | 2009 |
Combination therapy as first-line treatment of arterial hypertension.
Topics: Antihypertensive Agents; Atenolol; Captopril; Diltiazem; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Prazosin; Treatment Outcome | 2002 |
Clinical trial experience around the globe: focus on calcium-channel blockers.
Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Diabetic Angiopathies; Diltiazem; Humans; Hypertension; Meta-Analysis as Topic; Nifedipine; Stroke | 2003 |
Treatment of hypertension and prevention of ischemic stroke.
Topics: Algorithms; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Losartan; Perindopril; Stroke | 2004 |
Diltiazem-induced photodistributed hyperpigmentation.
Topics: Aged; Calcium Channel Blockers; Diltiazem; Facial Dermatoses; Humans; Hyperpigmentation; Hypertension; Male; Middle Aged; Photosensitivity Disorders | 2003 |
New advances in the field of calcium channel antagonists: cardiovascular effects and structure-activity relationships.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Calcium Channels; Cardiovascular System; Diltiazem; Humans; Hypertension; Nifedipine; Structure-Activity Relationship; Verapamil | 2003 |
Calcium channel blockers and the kidney.
Topics: Black or African American; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Diltiazem; Humans; Hypertension; Kidney; Kidney Failure, Chronic; United States; Verapamil | 2004 |
Long-acting diltiazem HCl for the chronotherapeutic treatment of hypertension and chronic stable angina pectoris.
Topics: Angina Pectoris; Chronic Disease; Chronotherapy; Delayed-Action Preparations; Diltiazem; Humans; Hypertension | 2005 |
[Indications for calcium channel antagonist therapy according to the latest large clinical trials].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Female; Humans; Hypertension; Male; Meta-Analysis as Topic; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Treatment Outcome; Verapamil | 2005 |
Understanding the calcium channel blockers.
Topics: Action Potentials; Angina Pectoris; Animals; Arrhythmias, Cardiac; Arteriosclerosis; Calcium; Calcium Channel Blockers; Calmodulin; Cardiomyopathy, Hypertrophic; Critical Care; Diltiazem; Heart Conduction System; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Nursing Care; Receptors, Adrenergic, beta; Verapamil | 1984 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Humans; Hypertension; Ion Channels; Nifedipine; Time Factors; Vascular Resistance; Vasodilation; Verapamil | 1984 |
Treatment of vasospastic angina.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anemia; Angina Pectoris, Variant; Atropine; Diltiazem; Drug Therapy, Combination; Epoprostenol; Exercise Therapy; Female; Humans; Hypertension; Hyperthyroidism; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Nitroprusside; Nylidrin; Verapamil | 1983 |
Clinical applications of slow channel blocking compounds.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Coronary Disease; Coronary Vessels; Diltiazem; Drug Interactions; Electrophysiology; Heart; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Ischemic Attack, Transient; Nifedipine; Verapamil | 1983 |
Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem.
Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Arrhythmias, Cardiac; Benzazepines; Calcium; Cardiovascular System; Diltiazem; Dogs; Electrophysiology; Humans; Hypertension; Ion Channels; Kinetics; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Infarction; Nifedipine; Pyridines; Sheep; Tetrodotoxin; Vasodilator Agents; Verapamil | 1980 |
Calcium channel blocking drugs.
Topics: Anesthesia; Angina Pectoris; Animals; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Diltiazem; Heart Conduction System; Hemodynamics; Humans; Hypertension; Ion Channels; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Tachycardia; Verapamil | 1983 |
Hypertension: calcium-blocking agents in treatment.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Hypertension; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Verapamil | 1984 |
Slow channel blockers.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Constipation; Diltiazem; Dizziness; Dose-Response Relationship, Drug; Heart; Humans; Hypertension; Hypotension; Myocardial Contraction; Nausea; Nifedipine; Verapamil | 1983 |
[Calcium antagonists in cardiology].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Diltiazem; Heart Diseases; Humans; Hypertension; Nifedipine; Verapamil | 1983 |
Calcium antagonists. Clinical use in the treatment of systemic hypertension.
Topics: Angina Pectoris; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1983 |
[Calcium antagonists in the therapy of hypertension].
Topics: Biological Transport; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Kidney; Nifedipine; Time Factors; Verapamil | 1983 |
Treatment of hypertension with calcium channel blockers: European data.
Topics: Age Factors; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Diltiazem; Europe; Humans; Hypertension; Japan; Nifedipine; Physical Exertion; Renin-Angiotensin System; Sympathetic Nervous System; Time Factors; Vasodilation; Verapamil; Water-Electrolyte Balance | 1984 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil | 1983 |
Calcium antagonists in the treatment of hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Hypertension; Nifedipine; Vascular Resistance; Verapamil | 1982 |
Diltiazem: ten years of clinical experience in the treatment of hypertension.
Topics: Antihypertensive Agents; Black People; Clinical Trials as Topic; Diltiazem; Female; Heart; Hemodynamics; Humans; Hypertension; Kidney; Male; Quality of Life; White People | 1995 |
Intracranial pheochromocytoma--a case of noradrenaline-secreting glomus jugulare tumor.
Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Diagnosis, Differential; Diltiazem; Embolization, Therapeutic; Female; Glomus Jugulare Tumor; Humans; Hypertension; Nifedipine; Norepinephrine; Pheochromocytoma | 1995 |
Poisoning with anti-hypertensive drugs: calcium antagonists.
Topics: Age Factors; Antihypertensive Agents; Calcium; Diltiazem; Drug Overdose; Humans; Hypertension; Nifedipine; Risk Factors; Verapamil | 1995 |
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Studies; Humans; Hypertension; Lisinopril; Longitudinal Studies; Research Design; Survival Rate | 1994 |
The Nordic Diltiazem Study (NORDIL). A prospective intervention trial of calcium antagonist therapy in hypertension.
Topics: Aged; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic | 1993 |
Managing the older patient with hypertension.
Topics: Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Atenolol; Delayed-Action Preparations; Diltiazem; Enalapril; Forecasting; Humans; Hypertension; Randomized Controlled Trials as Topic; Systole | 1993 |
Similarities and differences between calcium antagonists: pharmacological aspects.
Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Nifedipine; Vasodilator Agents; Verapamil | 1993 |
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Catheter Ablation; Cerebrovascular Disorders; Diabetes Complications; Digoxin; Diltiazem; Embolism; Humans; Hypertension; Thromboembolism; Verapamil; Warfarin | 1996 |
Reference-based pricing in British Columbia: implications for cardiologists--an analysis.
Topics: Angina Pectoris; Antihypertensive Agents; British Columbia; Cardiovascular Agents; Cost Control; Diltiazem; Drug Administration Schedule; Drug Costs; Drugs, Generic; Humans; Hypertension; Patient Compliance; Prescription Fees; Quality of Health Care | 1997 |
The role of diltiazem in treating hypertension and coronary artery disease: new approaches to preventing first events.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Diltiazem; Humans; Hypertension; Myocardial Ischemia | 1997 |
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Canada; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Patient Compliance; Primary Health Care | 1997 |
Diversity of calcium antagonists.
Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Kidney Failure, Chronic; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Verapamil | 1997 |
Targeting nonalloimmune-dependent pathways.
Topics: Antihypertensive Agents; Coronary Artery Bypass; Coronary Disease; Diltiazem; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Photopheresis; Postoperative Complications; Pravastatin; Reoperation; Risk Factors | 1997 |
Chronotherapy for coronary heart disease.
Topics: Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chronotherapy; Coronary Disease; Delivery of Health Care; Diltiazem; Heart Rate; Humans; Hypertension; Risk Factors; Tissue Survival | 1997 |
Use of calcium channel blockers in hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Heart Diseases; Humans; Hypertension; Longitudinal Studies; Mibefradil; Nifedipine; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil | 1998 |
Anomalies in the dosing of diltiazem.
Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Chemistry, Pharmaceutical; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Drug Prescriptions; Humans; Hypertension | 2000 |
Heart rate-lowering and -regulating effects of once-daily sustained-release diltiazem.
Topics: Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Meta-Analysis as Topic; Middle Aged | 2001 |
Heart rate-lowering calcium antagonists in hypertensive post-myocardial infarction patients.
Topics: Aged; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Humans; Hypertension; Lung Diseases; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Verapamil | 2001 |
The INSIGHT and NORDIL trials: Are calcium antagonists equivalent to established drug therapies for cardiovascular protection?
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Humans; Hypertension; Nifedipine; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
[Are newer antihypertensive agents better than the older ones? Results of trials (CAPPP, STOP-2, NORDIL, INSIGHT and ALLHAT) with newer antihypertensive agents].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Hypolipidemic Agents; Middle Aged; Nifedipine; Prospective Studies; Randomized Controlled Trials as Topic | 2001 |
Clinical experience with a once-daily, extended-release formulation of diltiazem in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Constipation; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Drug Monitoring; Female; Headache; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1992 |
Sustained-release diltiazem and prevention of cardiovascular risk in hypertensive patients.
Topics: Cardiovascular Diseases; Delayed-Action Preparations; Diltiazem; Humans; Hypertension; Risk Factors | 1990 |
Diltiazem: its place in the antihypertensive armamentarium.
Topics: Antihypertensive Agents; Diltiazem; Humans; Hypertension | 1991 |
Diltiazem. A reappraisal of its pharmacological properties and therapeutic use.
Topics: Arrhythmias, Cardiac; Coronary Disease; Diltiazem; Humans; Hypertension; Muscle, Smooth | 1990 |
Effects of calcium antagonists on the hypertensive kidney.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Kidney; Kidney Function Tests; Verapamil | 1990 |
Review of the cardiovascular adversity of the calcium antagonist beta-blocker combination: implications for antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Drug Therapy, Combination; Heart Conduction System; Hemodynamics; Humans; Hypertension; Nifedipine; Verapamil | 1985 |
Calcium antagonists in the treatment of hypertension.
Topics: Biological Transport, Active; Calcium; Calcium Channel Blockers; Captopril; Diltiazem; Diuretics; Drug Resistance; Drug Therapy, Combination; Electrophysiology; Humans; Hypertension; Hypertension, Renovascular; Ion Channels; Kinetics; Methyldopa; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Sodium; Vascular Resistance; Verapamil | 1985 |
The central nervous system and effective antihypertensive effects of a calcium channel blocker.
Topics: Animals; Blood Platelets; Blood Proteins; Calcium; Calcium Channel Blockers; Cardenolides; Central Nervous System; Digoxin; Diltiazem; Humans; Hypertension; Hypothalamo-Hypophyseal System; Rats; Rats, Inbred SHR; Saponins; Sodium-Potassium-Exchanging ATPase | 1987 |
Experimental and clinical experience with the calcium antagonist diltiazem in hypertension.
Topics: Diltiazem; Humans; Hypertension | 1989 |
Calcium channel blockers. Potential medical benefits and side effects.
Topics: Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise; Humans; Hypertension; Nifedipine; United States; Verapamil | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
Calcium-channel blockers in the management of essential hypertension.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Verapamil | 1989 |
Selection of optimal drug therapy for the patient with angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Heart Rate; Heart Ventricles; Humans; Hypertension; Kidney Diseases; Lung Diseases; Myocardium; Nifedipine; Nitrates; Physical Exertion; Receptors, Adrenergic, beta; Systole; Vascular Diseases; Vasodilation; Verapamil | 1985 |
Antihypertensive therapy with calcium-channel blockers: comparison with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Drug Therapy, Combination; Europe; Heart Rate; Humans; Hypertension; Nifedipine; United States; Verapamil | 1985 |
[Calcium antagonists in the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Nifedipine; Vasodilator Agents; Verapamil | 1985 |
Effects of calcium entry blockers on renin-angiotensin-aldosterone system, renal function and hemodynamics, salt and water excretion and body fluid composition.
Topics: Animals; Blood Pressure; Body Fluids; Calcium Channel Blockers; Diltiazem; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Nifedipine; Nitrendipine; Renal Circulation; Renin-Angiotensin System; Verapamil; Water-Electrolyte Balance | 1985 |
Renal hemodynamic effects of a selected calcium antagonist.
Topics: Animals; Diltiazem; Glomerular Filtration Rate; Hypertension; Kidney; Renal Circulation; Urodynamics; Vasoconstriction; Vasodilation | 1988 |
[Calcium antagonists in arterial hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Drug Interactions; Heart Diseases; Hemodynamics; Humans; Hypertension; Nifedipine; Verapamil | 1988 |
Geriatric hypertension: the growing use of calcium-channel blockers.
Topics: Aged; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1988 |
The role of calcium channel blockers in the treatment of hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil | 1986 |
Kinetics and dynamics of calcium entry antagonists in systemic hypertension.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Diltiazem; Half-Life; Hemodynamics; Humans; Hypertension; Infusions, Parenteral; Injections, Intravenous; Kinetics; Liver Circulation; Nifedipine; Verapamil | 1986 |
Advances in calcium blocker therapy.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Disease; Diltiazem; Gastrointestinal Diseases; Heart Failure; Humans; Hypertension; Kinetics; Nifedipine; United States; Vascular Diseases; Verapamil | 1986 |
Calcium channel blockers in systemic hypertension.
Topics: Animals; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Interactions; Humans; Hypertension; Nifedipine; Rats; Verapamil | 1986 |
Calcium antagonism--with special reference to diltiazem.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart Conduction System; Hemodynamics; Humans; Hypertension; Kinetics; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction | 1986 |
Treatment of angina pectoris and hypertension with sustained-release calcium channel-blocking drugs.
Topics: Angina Pectoris; Biological Availability; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Verapamil | 1987 |
The role of calcium entry blockers in hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emergencies; Humans; Hypertension; Nifedipine; Verapamil | 1987 |
Calcium antagonists in patients with cardiovascular disease. Current perspectives.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atrial Fibrillation; Atrial Flutter; Benzazepines; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Diltiazem; Drug Interactions; Heart Failure; Humans; Hypertension; Hypertension, Pulmonary; Kinetics; Nifedipine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1985 |
Use of calcium antagonists in ventricular dysfunction.
Topics: Calcium Channel Blockers; Diltiazem; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hypertension; Myocardial Infarction; Nifedipine; Verapamil | 1985 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Humans; Hypertension; Myocardial Contraction; Myocardial Infarction; Nifedipine; Platelet Aggregation; Verapamil | 1985 |
Diltiazem. A review of its pharmacological properties and therapeutic efficacy.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Benzazepines; Coronary Disease; Digitalis Glycosides; Diltiazem; Drug Interactions; Electrophysiology; Heart; Hemodynamics; Humans; Hypertension; Kinetics; Muscle, Smooth; Muscle, Smooth, Vascular; Physical Exertion; Renal Circulation | 1985 |
Calcium channel blocking agents: physiologic basis of nursing intervention.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atrioventricular Node; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cardiomyopathy, Hypertrophic; Coronary Disease; Diltiazem; Electrophysiology; Humans; Hypertension; Myocardial Contraction; Nifedipine; Sinoatrial Node; Tachycardia; Vascular Resistance; Verapamil | 1985 |
Calcium-channel blockers and systemic hypertension.
Topics: Acute Disease; Angina Pectoris; Animals; Calcium Channel Blockers; Chronic Disease; Diltiazem; Drug Therapy, Combination; Hemodynamics; Humans; Hypercalcemia; Hypertension; Kinetics; Muscle, Smooth, Vascular; Nifedipine; Vasodilation; Verapamil | 1985 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltiazem; Heart Block; Heart Diseases; Heart Rate; Humans; Hypertension; Nifedipine; Verapamil | 1985 |
209 trial(s) available for diltiazem and Hypertension
| Article | Year |
|---|---|
Effect of diltiazem on exercise tolerance in patients with stable coronary artery disease and hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Coronary Artery Disease; Diltiazem; Exercise Tolerance; Humans; Hypertension | 2021 |
Comparison of nebivolol versus diltiazem in improving coronary artery spasm and quality of life in patients with hypertension and vasospastic angina: A prospective, randomized, double-blind pilot study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Angiography; Coronary Vasospasm; Cytokines; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation Mediators; Male; Middle Aged; Nebivolol; Nitric Oxide; Pilot Projects; Prospective Studies; Quality of Life; Vasodilation | 2020 |
An Equivalence Trial Comparing Labetalol and Diltiazem in Controlling Emergence Hypertension after Supratentorial Tumor Surgery.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diltiazem; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Supratentorial Neoplasms; Thailand; Young Adult | 2015 |
A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aged; Alleles; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diltiazem; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Female; Genotype; Humans; Hypertension; Male; Middle Aged; Nedd4 Ubiquitin Protein Ligases; Polymorphism, Single Nucleotide; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Ubiquitin-Protein Ligases; Vasodilator Agents | 2011 |
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diltiazem; Drug Administration Schedule; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Ramipril; Renal Insufficiency, Chronic; Treatment Outcome | 2013 |
[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Male; Myocardial Ischemia; Treatment Outcome | 2002 |
[Efficiency and safety of a long-lasting form of diltiazem in the treatment of hypertensive patients with ischemic heart disease].
Topics: Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Electrocardiography; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Severity of Illness Index | 2002 |
Efficacy and safety of a once daily graded-release diltiazem formulation in essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2003 |
[Study of the efficacity and tolerance of diltiazem LP 300 mg in 2000 hypertensive patients (alone or combined with an angiotensin converting enzyme inhibitor].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Time Factors; Treatment Outcome | 1999 |
[Effects of atenolol and diltiazem-SR on quality of life in the hypertensive patients].
Topics: Adult; Aged; Atenolol; Blood Pressure; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Quality of Life | 2003 |
Effects of nicardipine and diltiazem on the bispectral index and 95% spectral edge frequency.
Topics: Adult; Aged; Analysis of Variance; Anesthesia, Intravenous; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Electroencephalography; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Monitoring, Intraoperative; Nicardipine; Time Factors | 2003 |
The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.
Topics: Adult; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diastole; Diltiazem; Felodipine; Female; Heart Ventricles; Humans; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Systole; Treatment Outcome; Vascular Resistance | 2004 |
Antihypertensive efficacy of night-time graded-release diltiazem versus morning amlodipine in African Americans.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 2004 |
Effects of graded-release diltiazem versus ramipril, dosed at bedtime, on early morning blood pressure, heart rate, and the rate-pressure product.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronotherapy; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Ramipril | 2004 |
Pharmacokinetic and pharmacodynamic interactions between simvastatin and diltiazem in patients with hypercholesterolemia and hypertension.
Topics: Administration, Oral; Area Under Curve; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lipids; Liver Function Tests; Male; Middle Aged; Simvastatin; Treatment Outcome | 2004 |
Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers.
Topics: Adolescent; Adult; Amlodipine; Calcium Channel Blockers; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypertension; Indinavir; Male; Middle Aged; Ritonavir | 2005 |
Renoprotective effect of diltiazem in hypertensive type 2 diabetic patients with persistent microalbuminuria despite ACE inhibitor treatment.
Topics: Albuminuria; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diltiazem; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Prospective Studies | 2005 |
Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Diltiazem; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Office Visits; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Bedtime administration of graded-release diltiazem in patients with inadequate BP control: a tolerability and efficacy study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Statistics, Nonparametric | 2006 |
IMPPACT: Investigation of Medical Professionals and Patients Achieving Control Together.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canada; Diltiazem; Effect Modifier, Epidemiologic; Female; Humans; Hypertension; Male; Middle Aged; Office Visits; Self Care; Treatment Outcome | 2008 |
Interaction between renal function and microalbuminuria for cardiovascular risk in hypertension: the nordic diltiazem study.
Topics: Aged; Albuminuria; Antihypertensive Agents; Cardiovascular Diseases; Diltiazem; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Norway; Prognosis; Risk Factors; Sweden | 2008 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Humans; Hypertension; Ion Channels; Nifedipine; Time Factors; Vascular Resistance; Vasodilation; Verapamil | 1984 |
Calcium antagonists, firstline partners for betablockers in hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Nifedipine; Nitrendipine; Renin; Verapamil | 1984 |
Calcium channel blocking agents.
Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Hemodynamics; Humans; Hypertension; Ion Channels; Nifedipine; Pyridines; Systole; Verapamil | 1981 |
[Essential hypertension and calcium antagonists].
Topics: Adult; Aged; Benzazepines; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged | 1983 |
Diltiazem for treatment of essential hypertension: a double-blind controlled study with reserpine.
Topics: Adult; Aged; Benzazepines; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Reserpine | 1984 |
[Calcium antagonists in the treatment of arterial hypertension].
Topics: Benzazepines; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Nifedipine; Pyridines; Verapamil | 1982 |
[Dilzem: a new alternative to the therapy of angina pectoris and hypertension].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Electrocardiography; Humans; Hypertension; Nifedipine | 1981 |
Effects of calcium channel blockers on circulatory response to tracheal intubation in hypertensive patients: nicardipine versus diltiazem.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Nicardipine | 1995 |
Effects of diltiazem, metoprolol, enalapril and hydrochlorothiazide on frequency of ventricular premature complexes.
Topics: Analysis of Variance; Antihypertensive Agents; Cardiac Complexes, Premature; Diltiazem; Echocardiography; Electrocardiography, Ambulatory; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Metoprolol; Regression Analysis | 1994 |
Three-period crossover trial with ambulatory blood pressure monitoring for evaluating antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Capsules; Cross-Over Studies; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged | 1995 |
Antihypertensive efficacy of optimally titrated doses of once-daily sustained-release diltiazem: a placebo-controlled trial. DILPLACOMP Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome | 1995 |
[Diltiazem 180 mg in delayed release formulation in mild and moderate arterial hypertension].
Topics: Adult; Aged; Delayed-Action Preparations; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Time Factors | 1995 |
Cardiopulmonary response during exercise of a beta 1-selective beta-blocker (atenolol) and a calcium-channel blocker (diltiazem) in untrained subjects with hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Diltiazem; Double-Blind Method; Exercise; Female; Heart; Heart Rate; Humans; Hypertension; Lung; Male; Middle Aged; Single-Blind Method | 1993 |
Diltiazem vs. nicardipine on ambulatory and exercise blood pressure and on peripheral hemodynamics.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Exercise; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Plethysmography; Vascular Resistance | 1995 |
Efficacy and tolerability of felodipine ER and diltiazem SR as monotherapy in primary hypertension: a double-blind randomized study.
Topics: Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1994 |
[Evaluation of the therapeutic efficacy of delayed-action diltiazem in the treatment of mild and moderate hypertension, with ambulatory of blood pressure monitoring].
Topics: Adult; Aged; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1994 |
Hypertension and left ventricular hypertrophy in black people.
Topics: Amiloride; Black People; Diltiazem; Diuretics; Double-Blind Method; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male | 1995 |
Clinical efficacy of force titrated doses of diltiazem extended-release. A placebo controlled study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Middle Aged | 1995 |
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Studies; Humans; Hypertension; Lisinopril; Longitudinal Studies; Research Design; Survival Rate | 1994 |
Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.
Topics: Adult; Aged; Amlodipine; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electrophysiology; Female; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia | 1994 |
Effects of atenolol and diltiazem-SR on exercise and pressure load in hypertensive patients.
Topics: Adult; Aged; Atenolol; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Tolerance; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1994 |
[The antihypertensive and antianginal activity of Dilren--a prolonged-action calcium antagonist].
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Time Factors | 1994 |
Comparison of the efficacy and tolerability of an angiotensin converting enzyme inhibitor (lisinopril) versus a calcium channel antagonist (diltiazem SR) in the treatment of moderate to severe hypertension.
Topics: Blood Pressure; Diltiazem; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged | 1994 |
Electrocardiographic changes during antihypertensive treatment with diltiazem in relation to the achieved serum levels of the drug.
Topics: Adult; Aged; Diltiazem; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged | 1994 |
A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Electrolytes; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Dropouts | 1994 |
Once daily perindopril versus slow release diltiazem in the treatment of mild to moderate essential hypertension. Canadian Study Group on Perindopril.
Topics: Adolescent; Adult; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hypertension; Indoles; Male; Middle Aged; Perindopril | 1994 |
Antihypertensive efficacy of twice daily controlled release diltiazem using 24 hour intra-arterial blood pressure monitoring.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Diltiazem; Electrocardiography; Exercise Test; Female; Hand Strength; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Tilt-Table Test | 1994 |
[Pharmacokinetics and pharmacodynamics of slow release tablet of diltiazem in hypertensive patients with various renal functions].
Topics: Adult; Delayed-Action Preparations; Diltiazem; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged | 1994 |
[Antihypertensive efficacy and tolerability of diltiazem and enalapril, alone or in combination. DESG. Diltiazem Enalapril Study Group].
Topics: Adult; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Time Factors | 1994 |
The use of confidence intervals to describe the precision of trough/peak ratios for diltiazem CD in the treatment of hypertension.
Topics: Adult; Blood Pressure; Confidence Intervals; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1994 |
[Ambulatory measurement of blood pressure and efficacy of diltiazem. Influence of the timing of drug ingestion and initial blood pressure level].
Topics: Adult; Aged; Ambulatory Care; Blood Pressure; Blood Pressure Determination; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Time Factors | 1994 |
Calcium antagonist-induced gingival hyperplasia.
Topics: Adult; Aged; Calcium Channel Blockers; Cross-Sectional Studies; Diltiazem; Gingival Hyperplasia; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method; Verapamil | 1994 |
Comparative study of diltiazem and lisinopril in hypertension: similar improvements in diastolic function despite different effects on left ventricular mass and ambulatory blood pressure.
Topics: Blood Pressure; Diastole; Diltiazem; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Middle Aged; Ultrasonography | 1993 |
[The comparative effect of calcium antagonists on hemodynamics in patients with a stable form of essential hypertension (a randomized study)].
Topics: Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hypertension; Middle Aged; Nifedipine; Nisoldipine; Time Factors | 1994 |
Variability in plasma lipoprotein profiles when comparing diltiazem and propranolol.
Topics: Adult; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Propranolol | 1993 |
Calcium antagonists in heart transplant recipients: effects on cardiac and renal function and cyclosporine pharmacokinetics.
Topics: Cyclosporine; Diltiazem; Heart Transplantation; Hemodynamics; Humans; Hypertension; Immunosuppression Therapy; Kidney; Kidney Function Tests; Male; Middle Aged; Nifedipine | 1993 |
A new extended-release formulation of diltiazem HCl for the treatment of mild-to-moderate hypertension.
Topics: Blood Pressure; Capsules; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Female; Food; Humans; Hypertension; Male; Middle Aged; Retrospective Studies | 1993 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin | 1993 |
Comparison of the efficacy and safety of once-daily versus twice-daily formulations of diltiazem in the treatment of systemic hypertension. The Canadian Multicenter Diltiazem-CD Hypertension Trial Group.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Smoking | 1995 |
Comparative effects of diltiazem and lisinopril on left ventricular structure and filling in mild-to-moderate hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Ventricular Function, Left | 1995 |
Effectiveness and safety of diltiazem or lisinopril in treatment of hypertension after heart transplantation. Results of a prospective, randomized multicenter trail.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Diltiazem; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Lisinopril; Male; Middle Aged; Postoperative Complications; Prospective Studies; Treatment Outcome | 1996 |
Felodipine as an alternative to more expensive calcium antagonists in mild to moderate hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Costs; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Treatment Outcome | 1996 |
Comparison of nifedipine alone and with diltiazem or verapamil in hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Data Interpretation, Statistical; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Verapamil | 1996 |
Evaluation of blood pressure response to the combination of enalapril (single dose) and diltiazem ER (four different doses) in systemic hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1996 |
Renal effects of prolonged antihypertensive treatment with diltiazem.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diltiazem; Enzymes; Female; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Renal Circulation | 1996 |
The Diltiazem Different Doses Study--a dose-response study of once-daily diltiazem therapy for hypertension.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Placebos | 1996 |
24 hour blood pressure control with once-daily versus twice-daily formulations of diltiazem.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1995 |
Double-blind, parallel, comparative multicentre study of a new combination of diltiazem and hydrochlorothiazide with individual components in patients with mild or moderate hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Diastole; Diltiazem; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Sodium Chloride Symporter Inhibitors; Supine Position; Systole | 1996 |
Treatment of non-insulin-dependent diabetic hypertensive patients with Ca2+ channel blockers is associated with increased platelet sensitivity to insulin.
Topics: Angiotensin II; Antihypertensive Agents; Blood Platelets; Blood Pressure; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Isradipine; Male; Middle Aged; Vasoconstrictor Agents | 1995 |
Evaluation of enalapril/diltiazem ER in hypertensive patients with coexisting renal dysfunction. Enalapril/Diltiazem ER in Hypertensive Renal Disease Group.
Topics: Adult; Aged; Blood Pressure; Creatinine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Proteinuria | 1996 |
Administration-time-dependent effects of diltiazem on the 24-hour blood pressure profile of essential hypertension patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Diltiazem; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Sleep | 1997 |
Trough-to-peak ratio and circadian blood pressure profile after treatment with once-daily extended-release diltiazem, 240 mg, in patients with mild-to-moderate essential hypertension.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1997 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs | 1997 |
Changes in cerebral blood flow accompanied with reduction of blood pressure treatment in patients with hypertensive intracerebral hemorrhages.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Diltiazem; Hematoma; Humans; Hypertension; Middle Aged; Nitroglycerin; Thalamic Diseases; Trimethaphan | 1997 |
Antihypertensive effects of mibefradil: a double-blind comparison with diltiazem CD.
Topics: Adult; Aged; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Linear Models; Male; Mibefradil; Middle Aged; Multivariate Analysis; Tetrahydronaphthalenes | 1997 |
Additive effects of diltiazem and lisinopril in the treatment of elderly patients with mild-to-moderate hypertension.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Patient Compliance; Quality of Life | 1997 |
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists.
Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Edema; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Leg; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes | 1997 |
Aortic function in arterial hypertension determined by pressure-diameter relation: effects of diltiazem.
Topics: Adult; Aged; Analysis of Variance; Antihypertensive Agents; Aorta; Blood Pressure; Diltiazem; Elasticity; Female; Humans; Hypertension; Male; Middle Aged; Vasodilation | 1997 |
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Canada; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Patient Compliance; Primary Health Care | 1997 |
Comparison of amlodipine and long-acting diltiazem in the treatment of mild or moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diltiazem; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Patient Dropouts | 1997 |
Differential properties of mibefradil in hypertension and angina.
Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes | 1997 |
Comparison of the fixed combination of enalapril/diltiazem ER and their monotherapies in stage 1 to 3 essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Diltiazem; Double-Blind Method; Drug Combinations; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Outcome Assessment, Health Care | 1998 |
Clinical utility of long-term enalapril/diltiazem ER in stage 3-4 essential hypertension. Long-term Use of Enalapril/Diltiazem ER in Stage 3-4 Hypertension Group.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged | 1997 |
A placebo-controlled comparison of diltiazem and amlodipine monotherapy in essential hypertension using 24-h ambulatory monitoring.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardium; Organ Size | 1998 |
Calcium channel blockers attenuate cardiovascular responses to tracheal extubation in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Nicardipine; Orthopedic Procedures | 1998 |
Diltiazem-lidocaine combination for the attenuation of cardiovascular responses to tracheal intubation in hypertensive patients.
Topics: Aged; Anesthetics, Intravenous; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Diltiazem; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Intubation, Intratracheal; Laryngoscopy; Lidocaine; Male; Middle Aged; Neuromuscular Depolarizing Agents; Neuromuscular Nondepolarizing Agents; Succinylcholine; Thiopental; Vecuronium Bromide | 1998 |
[Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery].
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Calcium Channel Blockers; Diabetes Complications; Diltiazem; Double-Blind Method; Elective Surgical Procedures; Etomidate; Female; Fentanyl; Halothane; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Premedication; Treatment Outcome | 1998 |
Long-term effects of diltiazem and atenolol on blood glucose, serum lipids, and serum urate in hypertensive patients. Swedish-Finnish Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Diltiazem; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Middle Aged; Quality of Life; Single-Blind Method; Time Factors; Uric Acid | 1999 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States | 1999 |
Comparison of clinical efficacy and adverse effects between extended-release felodipine and slow-release diltiazem in patients with isolated systolic hypertension.
Topics: Adult; Aged; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Middle Aged | 1999 |
Comparisons of the effects of different long-acting delivery systems on the pharmacokinetics and pharmacodynamics of diltiazem.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diltiazem; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Hypertension; Male; Middle Aged | 1999 |
Antihypertensive efficacy and tolerability of once-daily sustained-release diltiazem alone and in combination with ramipril in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Ramipril | 1999 |
Progress report on the Nordic diltiazem study (NORDIL): an outcome study in hypertensive patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cohort Studies; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Scandinavian and Nordic Countries; Treatment Outcome | 1999 |
Effects of diltiazem retard on ambulatory blood pressure and heart rate variability in patients with essential hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; Drug Monitoring; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Parasympathetic Nervous System; Sympathetic Nervous System; Vagus Nerve | 2000 |
Effect of antihypertensive treatment on office and self-measured blood pressure: the Autodil study.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diastole; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Office Visits; Prospective Studies; Self-Examination; Systole | 2000 |
Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Female; Humans; Hypertension; Life Tables; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Risk Factors; Single-Blind Method; Stroke | 2000 |
[Calcium channel blocking agents and albuminuria in diabetic and hypertensive patients. A pilot study].
Topics: Absorption; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Creatinine; Diabetes Complications; Diltiazem; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney Glomerulus; Kidney Tubules; Middle Aged; Pilot Projects; Plasma Volume; Pressure; Prospective Studies; Radiopharmaceuticals; Technetium Tc 99m Aggregated Albumin | 2000 |
Treatment of arterial hypertension in the elderly with diltiazem vs ramipril.
Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Diltiazem; Female; Humans; Hypertension; Male; Ramipril; Single-Blind Method | 2000 |
[Effect of dilren on hemodynamics of patients with essential hypertension].
Topics: Aged; Circadian Rhythm; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Vasodilator Agents | 2000 |
The effects of diltiazem on hemodynamics and seizure duration during electroconvulsive therapy.
Topics: Adult; Aged; Blood Pressure; Cardiovascular Agents; Cross-Over Studies; Diltiazem; Double-Blind Method; Electroconvulsive Therapy; Electroencephalography; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Seizures; Tachycardia | 2001 |
Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Disease; Diltiazem; Diuretics; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Myocardial Ischemia | 2001 |
Influence of diltiazem on the pharmacokinetics of amlodipine in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Diltiazem; Humans; Hypertension | 2001 |
[Controlled release diltiazem in monotherapy of hypertension--time of drug administration and circadian blood pressure pattern].
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 2000 |
Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diltiazem; Diuretics; Drug Interactions; Erectile Dysfunction; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Pulsatile Flow; Purines; Receptors, Angiotensin; Sildenafil Citrate; Single-Blind Method; Sulfones | 2001 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome | 2001 |
Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation.
Topics: Aged; Anesthesia; Anesthesia Recovery Period; Antihypertensive Agents; Blood Pressure; Diltiazem; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Neurosurgical Procedures; Nicardipine; Postoperative Period | 2002 |
Influence of age, sex and blood pressure on the principal endpoints of the Nordic Diltiazem (NORDIL) Study.
Topics: Adrenergic beta-Antagonists; Aged; Aging; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Prospective Studies; Sex Characteristics; Stroke; Survival Analysis | 2002 |
[Comparative hypotensive effectiveness of various calcium antagonists in patients with persistent essential hypertension (randomized study)].
Topics: Blood Pressure; Calcium Channel Blockers; Chronic Disease; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Stroke Volume | 1992 |
[Slow release diltiazem as monotherapy in primary mild to moderate hypertension. A multicenter study].
Topics: Adult; Blood Pressure; Diltiazem; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1992 |
Sustained antihypertensive activity of diltiazem SR: double-blind, placebo-controlled study with 24-hour ambulatory blood pressure monitoring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Blood Pressure Determination; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Time Factors | 1992 |
Clinical experience with a once-daily, extended-release formulation of diltiazem in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Constipation; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Drug Monitoring; Female; Headache; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1992 |
A comparison of the safety of therapeutically equivalent doses of isradipine and diltiazem for treatment of essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Isradipine; Male; Middle Aged | 1992 |
A dose-response trial of once-daily diltiazem.
Topics: Adolescent; Adult; Blood Pressure; Capsules; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Placebos; United States | 1992 |
A dose escalation trial comparing the combination of diltiazem SR and hydrochlorothiazide with the monotherapies in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Middle Aged | 1992 |
[Assessment of the anti-hypertensive effect of diltiazem in delayed-action capsules by ambulatory monitoring of arterial pressure].
Topics: Adult; Aged; Blood Pressure Monitors; Capsules; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1992 |
24-hour efficacy of once-daily diltiazem in essential hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Research Design | 1992 |
Analysis of the daily variation in blood pressure and pharmacokinetics after single or repeated administration of clentiazem to patients with essential hypertension.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Female; Heart; Humans; Hypertension; Male; Middle Aged; Pulse | 1992 |
Calcium entry blockade and adrenergic vascular reactivity in hypertensives: differences between nicardipine and diltiazem.
Topics: Adrenergic alpha-Antagonists; Adult; Biological Transport; Blood Vessels; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Nicardipine; Norepinephrine; Propranolol; Vasoconstriction; Vasodilation | 1991 |
Effects of sustained-release diltiazem on blood pressure and serum lipids: a multicenter, randomized, placebo-controlled study.
Topics: Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Tolerance; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged | 1990 |
Comparative study on monotherapy with sustained-release diltiazem 300 mg and enalapril 20 mg in mild to moderate arterial hypertension.
Topics: Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Tolerance; Electrocardiography; Enalapril; Humans; Hypertension; Middle Aged | 1990 |
Efficacy and tolerance of sustained-release diltiazem 300 mg and a diuretic in the elderly.
Topics: Aged; Aging; Blood Pressure; Delayed-Action Preparations; Diltiazem; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Triamterene | 1990 |
Demographic factors and the antihypertensive effect of diltiazem.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Body Weight; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Sex Characteristics | 1991 |
Pharmacokinetic properties and antihypertensive efficacy of once-daily diltiazem.
Topics: Adult; Aged; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1991 |
Diltiazem: its place in the antihypertensive armamentarium.
Topics: Antihypertensive Agents; Diltiazem; Humans; Hypertension | 1991 |
The effects of nisoldipine, diltiazem, nifedipine, and verapamil on hemodynamic parameters and red blood cells-platelet interactions in patients with arterial hypertension.
Topics: Adult; Aged; Arteries; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Diltiazem; Erythrocytes; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nisoldipine; Verapamil | 1991 |
Chronic effects of diltiazem on the hemodynamic and sympathoadrenal tone in responsive and nonresponsive hypertensive patients at rest and during isometric exercise.
Topics: Adrenal Glands; Cardiovascular System; Catecholamines; Diltiazem; Drug Administration Schedule; Exercise; Female; Hemodynamics; Humans; Hypertension; Male; Rest; Sympathetic Nervous System | 1991 |
Treatment of mild-to-moderate hypertension: comparison between a calcium-channel blocker and a potassium-sparing diuretic.
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Diltiazem; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Single-Blind Method; Time Factors; Triamterene | 1991 |
Studies of captopril alone and in combination with the benzothiazepine diltiazem or the dihydropyridine nifedipine in treating essential hypertension.
Topics: Adult; Aged; Blood Pressure; Captopril; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Nifedipine; Single-Blind Method | 1991 |
Comparison of diltiazem, nitrendipine, and their combination for systemic hypertension and stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitrendipine | 1991 |
Hemodynamic effects of Ro 23-6152 in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Diltiazem; Double-Blind Method; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Stroke Volume; Vascular Resistance | 1991 |
[Ambulatory ergometric and pressurometric results with a daily dose of 240 mg of diltiazem in labile hypertensive patients with threshold ergometry].
Topics: Adult; Blood Pressure; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic | 1991 |
Effects of diltiazem on long-term outcome after acute myocardial infarction in patients with and without a history of systemic hypertension. The Multicenter Diltiazem Postinfarction Trial Research Group.
Topics: Adult; Aged; Diltiazem; Double-Blind Method; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Prognosis; Pulmonary Edema; Retrospective Studies | 1991 |
Effects of diltiazem and metoprolol on blood pressure, adverse symptoms and general well-being. The Swedish Diltiazem-Metoprolol Multi-Centre Study Group.
Topics: Adult; Aged; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Quality of Life | 1991 |
A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women.
Topics: Aged; Atenolol; Blood Pressure; Diltiazem; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Quality of Life | 1991 |
Twenty-four hour ambulatory blood pressure profile of a new slow-release formulation of diltiazem in mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitors; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1991 |
The determinants of response to diltiazem in hypertension.
Topics: Adult; Age Factors; Aged; Blood Pressure; Delayed-Action Preparations; Diltiazem; Female; Half-Life; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Regression Analysis; Renin; Sodium; Vasodilation | 1991 |
Effects of hydrochlorothiazide, diltiazem and enalapril on mononuclear cell sodium and magnesium levels in systemic hypertension.
Topics: Aged; Diltiazem; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Leukocytes, Mononuclear; Magnesium; Male; Sodium; Water-Electrolyte Balance | 1991 |
Natriuretic effect of calcium-channel blockers in hypertensives.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nifedipine | 1991 |
Diltiazem and atenolol in essential hypertension: additivity of effects on blood pressure and cardiac conduction with combination therapy.
Topics: Atenolol; Atrial Natriuretic Factor; Blood Pressure; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Heart Conduction System; Heart Rate; Humans; Hypertension | 1990 |
A comparison of diltiazem, esmolol, nifedipine and nitroprusside therapy of post-CABG hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Coronary Artery Bypass; Coronary Circulation; Diltiazem; Energy Metabolism; Ferricyanides; Humans; Hypertension; Infusions, Intravenous; Myocardium; Nifedipine; Nitroprusside; Postoperative Complications; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic | 1990 |
Trial of slow release diltiazem for essential hypertension in general practice.
Topics: Blood Pressure; Delayed-Action Preparations; Diltiazem; Family Practice; Humans; Hypertension; New Zealand; Single-Blind Method | 1991 |
Efficacy and safety of clentiazem in patients with essential hypertension: results of an early pilot test.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pilot Projects | 1991 |
Once daily compared with twice daily administration of slow-release diltiazem as monotherapy for hypertension.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1991 |
Diltiazem compared with metoprolol as add-on-therapies to diuretics in hypertension. Swedish Diltiazem-Metoprolol Multicentre Study Group.
Topics: Aged; Blood Pressure; Diltiazem; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1991 |
A comparison of diltiazem and metoprolol in hypertension. Swedish Diltiazem-Metoprolol Multicentre Study Group.
Topics: Blood Pressure; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged | 1990 |
Antihypertensive monotherapy with tablet (prompt-release) diltiazem: multicenter controlled trials.
Topics: Adult; Aged; Diltiazem; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Tablets | 1990 |
Comparative effects of propranolol and diltiazem on systolic and diastolic left ventricular function in essential hypertension.
Topics: Blood Pressure; Diltiazem; Double-Blind Method; Echocardiography; Female; Heart Rate; Humans; Hypertension; Male; Propranolol; Ventricular Function, Left | 1990 |
Effects of calcium channel blockade on calcium homeostasis in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium; Calcium Channel Blockers; Captopril; Diltiazem; Female; Homeostasis; Humans; Hypertension; Male; Middle Aged; Parathyroid Hormone; Renin | 1990 |
Effects of different calcium antagonists on proteinuria associated with diabetes mellitus.
Topics: Aged; Creatinine; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diltiazem; Female; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Nifedipine; Prospective Studies; Proteinuria | 1990 |
Analysis of time trends, individual subject responses and background variation in crossover factorial studies with antihypertensive drugs.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension | 1990 |
[The results of a clinical study of the preparation kardil].
Topics: Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipine; USSR; Verapamil | 1990 |
Comparative effects of diltiazem sustained-release and captopril on blood pressure control and plasma lipoproteins in primary hypertension: a randomized, double-blind, crossover study.
Topics: Adolescent; Adult; Aged; Apolipoproteins; Blood Pressure; Captopril; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hypertension; Lipids; Lipoproteins; Middle Aged | 1990 |
Effects of diltiazem or propranolol during exercise training of hypertensive men.
Topics: Adolescent; Adult; Blood Pressure; Diltiazem; Exercise; Exercise Test; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxygen; Propranolol; Pulmonary Gas Exchange; Weight Lifting | 1990 |
Comparative effects of diltiazem sustained-release formulation and metoprolol on ambulatory blood pressure and plasma lipoproteins.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Lipoproteins; Male; Metoprolol; Middle Aged; Random Allocation | 1990 |
An assessment of diltiazem and hydrochlorothiazide in hypertension. Application of factorial trial design to a multicenter clinical trial of combination therapy.
Topics: Adult; Analysis of Variance; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Research Design | 1990 |
Effects of diltiazem on cation transport across erythrocyte membranes of hypertensive humans.
Topics: Blood Pressure; Diltiazem; Double-Blind Method; Erythrocyte Membrane; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Potassium; Random Allocation; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Endocrine and vascular responses in hypertensive patients to long-term treatment with diltiazem.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Body Weight; Diltiazem; Dinoprostone; Endocrine Glands; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prostaglandins E; Pulse; Renin | 1987 |
A double-blind, randomized, crossover comparison of equivalent (by weight) oral doses of verapamil and diltiazem in patients with mild to moderate hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Random Allocation; Verapamil | 1989 |
Calcium channel blockers. Potential medical benefits and side effects.
Topics: Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise; Humans; Hypertension; Nifedipine; United States; Verapamil | 1989 |
Diltiazem and left ventricular mass regression.
Topics: Cardiomegaly; Diltiazem; Humans; Hypertension; Randomized Controlled Trials as Topic | 1989 |
Effect of diltiazem on left ventricular mass and diastolic filling in mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diastole; Diltiazem; Echocardiography, Doppler; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Prospective Studies; Random Allocation | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
The effects of verapamil, diltiazem, nifedipine and propranolol on metabolic control in hypertensives with non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Diltiazem; Female; Fructosamine; Glycated Hemoglobin; Heart Rate; Hexosamines; Humans; Hypertension; Insulin; Male; Middle Aged; Nifedipine; Propranolol; Triglycerides; Verapamil | 1989 |
Sustained-release diltiazem: duration of antihypertensive effect.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Random Allocation; Time Factors | 1989 |
Metabolic effects of diltiazem and atenolol: results from a randomized, double-blind study with parallel groups.
Topics: Adult; Atenolol; Blood Glucose; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Insulin; Lipoproteins; Male; Middle Aged; Random Allocation | 1989 |
[Changes in central hemodynamics and renal blood flow after correction of arterial hypertension with diltiazem].
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Diltiazem; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renal Circulation | 1989 |
Effects of long-term antihypertensive treatment on glucose metabolism.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Diabetes Mellitus; Diltiazem; Glucose; Humans; Hypertension; Metoprolol; Random Allocation; Risk Factors | 1989 |
Diltiazem as monotherapy in treatment of mild to moderate essential hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Safety | 1989 |
Antihypertensive effect of diltiazem in a slow-release formulation for mild to moderate essential hypertension.
Topics: Adult; Aged; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Random Allocation; Supination | 1989 |
Angiotensin-converting enzyme inhibitor versus calcium antagonist in the treatment of hypertension.
Topics: Adult; Blood Pressure; Diltiazem; Enalapril; Female; Humans; Hypertension; Male; Middle Aged | 1987 |
Individual responses to converting enzyme inhibitors and calcium antagonists.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Enalapril; Enalaprilat; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation; Time Factors | 1988 |
Antihypertensive therapy with calcium-channel blockers: comparison with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Drug Therapy, Combination; Europe; Heart Rate; Humans; Hypertension; Nifedipine; United States; Verapamil | 1985 |
Efficacy and safety of sustained-release diltiazem as replacement therapy for beta blockers and diuretics for stable angina pectoris and coexisting essential hypertension: a multicenter trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Diuretics; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Propranolol; Sodium Chloride Symporter Inhibitors | 1987 |
Diltiazem-induced left ventricular mass regression in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Humans; Hypertension; Middle Aged; Propranolol | 1987 |
Calcium entry blockers for systemic hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension | 1987 |
Diltiazem and captopril alone or in combination for treatment of mild to moderate systemic hypertension.
Topics: Adult; Blood Pressure; Captopril; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation | 1988 |
Metabolic effects of antihypertensive therapy with a calcium antagonist.
Topics: Blood Glucose; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Random Allocation | 1988 |
Comparison of diltiazem and hydrochlorothiazide for treatment of patients 60 years of age or older with systemic hypertension.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Potassium; Random Allocation | 1988 |
Diltiazem maintains renal vasodilation without hyperfiltration in hypertension: studies in essential hypertension man and the spontaneously hypertensive rat.
Topics: Adult; Aged; Angiotensin I; Animals; Blood Pressure; Diltiazem; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vascular Resistance; Vasodilation | 1987 |
Diltiazem in hypertensive patients with type II diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Blood Platelets; Blood Pressure; Diabetes Mellitus, Type 2; Diltiazem; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Patient Compliance | 1988 |
Comparison of equal-weight oral dosages of verapamil hydrochloride and diltiazem hydrochloride in patients with mild to moderate hypertension.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation; Verapamil | 1988 |
Postoperative hypertension: a comparison of diltiazem, nifedipine, and nitroprusside.
Topics: Clinical Trials as Topic; Coronary Artery Bypass; Diltiazem; Female; Ferricyanides; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardium; Nifedipine; Nitroprusside; Postoperative Complications; Prospective Studies; Random Allocation | 1988 |
Diltiazem and propranolol in mild to moderate essential hypertension as monotherapy or with hydrochlorothiazide.
Topics: Adult; Age Factors; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol; Random Allocation | 1987 |
Exercise capacity and hemodynamics in persons aged 20 to 50 years with systemic hypertension treated with diltiazem and atenolol.
Topics: Adult; Atenolol; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Exercise Test; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Random Allocation | 1987 |
[Acute treatment of arterial hypertension using calcium antagonists: comparison between diltiazem and nifedipine].
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emergencies; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin | 1987 |
Comparison of diltiazem and atenolol in young, physically active men with essential hypertension.
Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Random Allocation | 1987 |
Sustained-release diltiazem compared with atenolol monotherapy for mild to moderate systemic hypertension.
Topics: Atenolol; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation | 1987 |
Efficacy, electrocardiographic and renal effects of intravenous diltiazem for essential hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Diltiazem; Electrocardiography; Glomerular Filtration Rate; Humans; Hypertension; Infusions, Intravenous; Kidney; Male; Middle Aged; Renal Circulation | 1987 |
Characterization of antihypertensive therapy by whole-day blood pressure monitoring.
Topics: Adult; Aged; Blood Pressure Determination; Body Weight; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic | 1988 |
Diltiazem compared with hydrochlorothiazide in the treatment of mild-to-moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Diltiazem; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse; Time Factors | 1988 |
The role of calcium channel blockers in the treatment of hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil | 1986 |
Diltiazem as monotherapy for systemic hypertension: a multicenter, randomized, placebo-controlled trial.
Topics: Age Factors; Aged; Benzazepines; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Dizziness; Double-Blind Method; Edema; Female; Headache; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Random Allocation | 1986 |
Calcium-channel blockers for combined angina pectoris and systemic hypertension.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Diltiazem; Double-Blind Method; Heart; Heart Rate; Humans; Hypertension; Middle Aged; Myocardium; Nifedipine; Oxygen Consumption; Physical Exertion; Propranolol; Random Allocation; Risk; Verapamil | 1986 |
[The effect of the Ca2+ antagonist diltiazem on the respiratory function in chronic obstructive lung diseases].
Topics: Adult; Asthma; Clinical Trials as Topic; Diltiazem; Drug Evaluation; Female; Humans; Hypertension; Lung Diseases, Obstructive; Male; Respiration | 1986 |
Comparison of hydrochlorothiazide and sustained-release diltiazem for mild-to-moderate systemic hypertension.
Topics: Adult; Age Factors; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Potassium; Random Allocation | 1987 |
Calcium-channel blockers for combined systemic hypertension and myocardial ischemia.
Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Diltiazem; Double-Blind Method; Hemodynamics; Humans; Hypertension; Nifedipine; Random Allocation; Time Factors; Verapamil | 1987 |
Effects of hydrochlorothiazide and diltiazem on reflex vasoconstriction in hypertension.
Topics: Adult; Blood Pressure; Diltiazem; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lower Body Negative Pressure; Male; Middle Aged; Random Allocation; Renin-Angiotensin System; Vascular Resistance; Vasoconstriction | 1987 |
Effect of sodium balance and calcium channel blocking drugs on blood pressure responses.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Sodium | 1987 |
Antihypertensive and metabolic effects of diltiazem and nifedipine.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Physical Exertion; Random Allocation | 1986 |
[Prevention of hypertensive attacks after carotid surgery. The value of nifedipine and diltiazem].
Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Carotid Arteries; Diltiazem; Drug Evaluation; Endarterectomy; Humans; Hypertension; Nifedipine; Postoperative Complications; Random Allocation | 1986 |
Diltiazem versus propranolol in essential hypertension: responses of rest and exercise blood pressure and effects on exercise capacity.
Topics: Blood Pressure; Diltiazem; Double-Blind Method; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxygen Consumption; Physical Exertion; Propranolol; Random Allocation | 1987 |
Effect of diltiazem hydrochloride in essential hypertension.
Topics: Adult; Aged; Benzazepines; Blood Pressure; Clinical Trials as Topic; Diltiazem; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Time Factors | 1985 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Humans; Hypertension; Myocardial Contraction; Myocardial Infarction; Nifedipine; Platelet Aggregation; Verapamil | 1985 |
Effects of diltiazem on serum lipids, exercise performance and blood pressure: randomized, double-blind, placebo-controlled evaluation for systemic hypertension.
Topics: Benzazepines; Blood Pressure; Cholesterol; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Physical Exertion; Prospective Studies; Random Allocation; Time Factors; Triglycerides | 1985 |
Diuretics versus calcium-channel blockers in systemic hypertension: a preliminary multicenter experience with hydrochlorothiazide and sustained-release diltiazem.
Topics: Aged; Benzazepines; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Time Factors | 1985 |
Comparison of diltiazem and nifedipine for both angina pectoris and systemic hypertension.
Topics: Adult; Aged; Angina Pectoris; Benzazepines; Blood Pressure; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitroglycerin; Physical Exertion; Random Allocation | 1985 |
Renal effects of diltiazem in primary hypertension.
Topics: Benzazepines; Blood Pressure; Body Fluids; Diltiazem; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Natriuresis; Renal Circulation; Vascular Resistance | 1986 |
Comparative effects of diltiazem and hydrochlorothiazide in blacks with systemic hypertension.
Topics: Adult; Aged; Benzazepines; Black or African American; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Time Factors | 1985 |
262 other study(ies) available for diltiazem and Hypertension
| Article | Year |
|---|---|
Benzazepinone calcium channel blockers. 2. Structure-activity and drug metabolism studies leading to potent antihypertensive agents. Comparison with benzothiazepinones.
Topics: Acetylation; Animals; Antihypertensive Agents; Aorta; Benzazepines; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Hypertension; Male; Microsomes, Liver; Molecular Conformation; Molecular Structure; Pyrrolidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation | 1992 |
Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones.
Topics: Animals; Antihypertensive Agents; Aorta; Benzazepines; Calcium Channel Blockers; Guinea Pigs; Hypertension; Male; Molecular Conformation; Molecular Structure; Muscles; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation; X-Ray Diffraction | 1992 |
Synthesis, calcium-channel-blocking activity, and antihypertensive activity of 4-(diarylmethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
Topics: Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channel Blockers; Hypertension; Male; Molecular Structure; Muscle Contraction; Piperidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1991 |
A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11- dihydrodibenzo[b,e]-thiepin maleate and related compounds.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Chemistry, Physical; Dibenzothiepins; Heart Rate; Hypertension; Male; Methacholine Chloride; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction | 1991 |
2-Ethynylbenzenealkanamines. A new class of calcium entry blockers.
Topics: Alkynes; Amines; Animals; Calcium Channel Blockers; Coronary Circulation; Guinea Pigs; Hypertension; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation | 1988 |
Diltiazem-associated Photodistributed Hyperpigmentation.
Topics: Aged; Biopsy; Calcium Channel Blockers; Dermatologic Agents; Diltiazem; Female; Humans; Hyperpigmentation; Hypertension; Ointments; Photosensitivity Disorders; Skin; Tacrolimus; Treatment Outcome; Withholding Treatment | 2020 |
Engineering of Nanospheres Dispersed Microneedle System for Antihypertensive Action.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Cadmium Chloride; Chemical Engineering; Chemistry, Pharmaceutical; Diltiazem; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Hypertension; Male; Nanospheres; Needles; Nifedipine; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Skin | 2020 |
[An unusual case of gingival hyperplasia].
Topics: Antihypertensive Agents; Diltiazem; Female; Gingival Hyperplasia; Humans; Hypertension; Middle Aged; Radiography | 2014 |
ECG response: February 24, 2015.
Topics: Adrenergic beta-Antagonists; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Heart Block; Humans; Hypertension; Middle Aged; Sinoatrial Node | 2015 |
Exaggerated hypertensive response to combretastatin A-4 phosphate in hypertensive rats: Effective pharmacological inhibition by diltiazem.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Hypertension; Phosphates; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Stilbenes | 2015 |
Effect of angiotensin II-induced arterial hypertension on the voltage-dependent contractions of mouse arteries.
Topics: Action Potentials; Angiotensin II; Animals; Arteries; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cromakalim; Diltiazem; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Potassium; Vasodilation | 2016 |
Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Gene Expression Profiling; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Verapamil | 2016 |
Increased sensitivity to diltiazem hypotensive effect in an experimental model of high-renin hypertension.
Topics: Algorithms; Animals; Antihypertensive Agents; Area Under Curve; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Renin; Treatment Outcome | 2009 |
Ask the doctor. After being diagnosed with high blood pressure several years ago, I started taking diltiazem and Atacand. The results were good, giving me an average blood pressure of 110/65. I recently developed gastroenteritis and aspiration pneumoni
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Diltiazem; Gastroenteritis; Humans; Hypertension; Life Style; Pneumonia, Aspiration; Tetrazoles | 2009 |
Rapid large artery remodeling following the administration and withdrawal of calcium channel blockers in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Calcium Channel Blockers; Diltiazem; Endothelium; Hypertension; Male; Muscle Contraction; Nifedipine; Rats; Time Factors; Verapamil | 2009 |
[Acute generalised exanthematosus pustulosis (AGEP) due to diltiazem--a case report].
Topics: Acute Generalized Exanthematous Pustulosis; Aged; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Eruptions; Female; Humans; Hypertension | 2009 |
Continuous hypertension and tachycardia after resection of a hemangioblastoma behind the dorsal medulla oblongata: relationship to sympathetic overactivity at the neurogenic vasomotor center.
Topics: Adrenergic beta-Antagonists; Autonomic Nervous System Diseases; Baroreflex; Brain Stem Neoplasms; Calcium Channel Blockers; Diltiazem; Hemangioblastoma; Humans; Hypertension; Magnetic Resonance Imaging; Male; Medulla Oblongata; Morpholines; Postoperative Complications; Solitary Nucleus; Tachycardia; Urea; Vasomotor System; Young Adult | 2010 |
Increased blood flow induces oxidative stress through an endothelium- and nitric oxide-independent mechanism.
Topics: Adult; Bradykinin; Calcium Channel Blockers; Diltiazem; Endothelium, Vascular; F2-Isoprostanes; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Oxidative Stress; Regional Blood Flow; Vasodilator Agents | 2010 |
Approach to the patient who is intolerant of statin therapy.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atorvastatin; Coronary Disease; Diltiazem; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Middle Aged; Pyrroles; Simvastatin | 2010 |
[Case of reversible posterior leukoencephalopathy syndrome after discontinuation of antihypertensive therapy].
Topics: Adult; Antihypertensive Agents; Brain Edema; Chronic Disease; Diltiazem; Humans; Hypertension; Kidney Diseases; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Patient Compliance; Severity of Illness Index; Treatment Outcome | 2010 |
Altered regulation of the epithelial sodium channel in hypertension. From genes to therapeutics.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Diltiazem; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Gene Expression Regulation; Humans; Hypertension; Nedd4 Ubiquitin Protein Ligases; Polymorphism, Single Nucleotide; Sodium Chloride Symporter Inhibitors; Ubiquitin-Protein Ligases | 2011 |
Simvastatin-induced myopathy, the role of interaction with diltiazem and genetic predisposition.
Topics: Aged, 80 and over; Antihypertensive Agents; Biotransformation; Cytochrome P-450 CYP3A; Diltiazem; Drug Interactions; Female; Hong Kong; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Middle Aged; Muscular Diseases; Polymorphism, Genetic; Simvastatin; Treatment Outcome | 2011 |
Aortic stiffness in vivo in hypertensive rat via echo-tracking: analysis of the pulsatile distension waveform.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Compliance; Diltiazem; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulsatile Flow; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Processing, Computer-Assisted; Time Factors; Ultrasonography | 2011 |
Letter: Photodistributed reticulated hyperpigmentation related to diltiazem.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Eruptions; Female; Humans; Hyperpigmentation; Hypertension; Photosensitivity Disorders | 2011 |
Diltiazem in the treatment of hypertension and ischemic heart disease.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Myocardial Ischemia; Risk Factors | 2011 |
Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats.
Topics: Acute Kidney Injury; Animals; Antibodies, Anti-Idiotypic; Antihypertensive Agents; Blood Pressure; Captopril; Diltiazem; Disease Models, Animal; Female; Fibrosis; Hydrochlorothiazide; Hypertension; Male; Proteinuria; Rats; Rats, Inbred Dahl; Sex Characteristics; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2012 |
HIV: a growing concern in the elderly population.
Topics: Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antihypertensive Agents; Azithromycin; CD4 Lymphocyte Count; Depressive Disorder; Diltiazem; Drug Interactions; Drug Monitoring; HIV Infections; Humans; Hypertension; Lopinavir; Male; Patient Compliance; Pharmacists; Renal Insufficiency; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 2012 |
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Digoxin; Diltiazem; Heart Diseases; Heart Rate; Humans; Hypertension; Ivabradine; Verapamil | 2012 |
Antiplatelet activity of semotiadil fumarate.
Topics: Adenosine Diphosphate; Adult; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Collagen; Diltiazem; Humans; Hypertension; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles | 2002 |
Comparison of home and office blood pressure in treated hypertensives in the Nordic Diltiazem (NORDIL) Study.
Topics: Aged; Antihypertensive Agents; Blood Pressure Determination; Clinical Trials as Topic; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norway; Reproducibility of Results; Sweden; Time Factors | 2002 |
[Effect of diltiazem on lipid profiles and heart rate in hypertensive patients].
Topics: Aged; Antihypertensive Agents; Apolipoprotein A-I; Blood Pressure; Calcium Channel Blockers; Cholesterol; Cholesterol, LDL; Diltiazem; Edema; Electrocardiography; Female; Flushing; Headache; Heart Rate; Humans; Hyperlipidemias; Hypertension; Leg; Male; Middle Aged; Treatment Outcome | 1999 |
Drug-induced atrioventricular block: prognosis after discontinuation of the culprit drug.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Calcium Channel Blockers; Diltiazem; Electrocardiography; Female; Follow-Up Studies; Heart Block; Humans; Hypertension; Israel; Male; Middle Aged; Prospective Studies; Treatment Failure; Verapamil | 2004 |
Effect of chronic tetrahydrobiopterin supplementation on blood pressure and proteinuria in 5/6 nephrectomized rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Arginine; Biopterins; Blood Pressure; Diltiazem; Glomerular Mesangium; Hypertension; Kidney Failure, Chronic; Male; Models, Animal; Nephrectomy; Nitric Oxide; Oxidative Stress; Proteinuria; Rats; Rats, Wistar; Vasodilator Agents | 2004 |
Diltiazem use in tacrolimus-treated renal transplant recipients.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Health Care Costs; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Tacrolimus | 2004 |
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertension; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Stroke; Vasodilator Agents; Ventricular Pressure | 2004 |
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil | 2005 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diltiazem; Diuretics; Drug Evaluation; Health Behavior; Humans; Hypertension; Losartan; Obesity; Renal Insufficiency; Sodium; Stroke; Verapamil | 2005 |
Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin.
Topics: Amides; Animals; Aorta, Thoracic; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; In Vitro Techniques; Indoles; Male; Mevalonic Acid; Muscle Relaxants, Central; Norepinephrine; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Inbred SHR; Simvastatin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Olmesartan medoxomil-induced angioedema.
Topics: Angioedema; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diltiazem; Face; Female; Humans; Hypertension; Imidazoles; Middle Aged; Neck; Olmesartan Medoxomil; Tetrazoles | 2007 |
Diltiazem-induced eosinophilic pleural effusion.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Clonidine; Diltiazem; Eosinophilia; Female; Humans; Hypertension; Pleural Effusion | 2007 |
Effect of enzymatically modified isoquercitrin in spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Quercetin; Rats; Rats, Inbred SHR; Time Factors | 2007 |
Bilateral posterior ischemic optic neuropathy associated with use of sildenafil.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypotension; Male; Optic Nerve; Optic Neuropathy, Ischemic; Phosphodiesterase Inhibitors; Piperazines; Purines; Retinal Artery; Risk Factors; Sildenafil Citrate; Simvastatin; Sulfones; Vision, Low | 2008 |
[Effect of diltiazem on diastolic performance of the hypertrophied left ventricle in patients with systemic hypertension and hypertrophic cardiomyopathy].
Topics: Administration, Oral; Adult; Benzazepines; Cardiomegaly; Cardiomyopathy, Hypertrophic; Diastole; Diltiazem; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction | 1983 |
Calcium channels in the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Diltiazem; Electric Conductivity; Heart; Hypertension; Ion Channels; Nifedipine; Vasodilator Agents; Verapamil | 1981 |
Calcium channel blockers for cardiovascular disorders.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Ion Channels; Nifedipine; Verapamil | 1982 |
Hypotensive effects of diltiazem to normals and essential hypertensives.
Topics: Administration, Oral; Adult; Benzazepines; Blood Pressure; Blood Urea Nitrogen; Diltiazem; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Renin; Time Factors | 1983 |
Antihypertensive therapy with diltiazem and comparison with hydrochlorothiazide.
Topics: Aged; Benzazepines; Blood Pressure; Diltiazem; Epinephrine; Female; Heart Rate; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Renin | 1984 |
Calcium entry blockers for the treatment of severe hypertension and hypertensive crisis.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Heart Ventricles; Hemodynamics; Humans; Hypertension; Nifedipine; Verapamil | 1984 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Diltiazem; Heart Failure; Humans; Hypertension; Nifedipine; Nitroprusside; Sympatholytics; Verapamil | 1984 |
Calcium channel blockers. New treatment for cardiovascular disease.
Topics: Adult; Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Diltiazem; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nifedipine; Verapamil | 1983 |
Common cellular disposition to hypertension and atherosclerosis.
Topics: Animals; Arteriosclerosis; Cells, Cultured; Diltiazem; Disease Susceptibility; Hypertension; Lipid Metabolism; Microscopy, Electron; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1984 |
Hypotensive and diuretic actions of diltiazem in spontaneously hypertensive and Wistar Kyoto rats.
Topics: Animals; Benzazepines; Blood Pressure; Diltiazem; Diuresis; Heart Rate; Hydralazine; Hypertension; Male; Natriuresis; Rats; Rats, Inbred Strains; Water-Electrolyte Balance | 1983 |
Effects of diltiazem on cardiovascular responses during exercise in systemic hypertension and comparison with propranolol.
Topics: Adult; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Propranolol; Random Allocation | 1983 |
Calcium channel blocking agents. Council on scientific affairs.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Asthma; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Diltiazem; Humans; Hypertension; Lung Diseases, Obstructive; Myocardial Infarction; Nifedipine; United States; United States Food and Drug Administration; Verapamil | 1983 |
Failure of antihypertensive therapy with diuretic, beta-blocking and calcium channel-blocking drugs to consistently reverse left ventricular diastolic filling abnormalities.
Topics: Benzazepines; Blood Pressure; Cardiac Volume; Diltiazem; Female; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol; Radionuclide Imaging; Stroke Volume | 1984 |
[Comparative hemodynamic effects of 2 vasodilators: dihydralazine and diltiazem in permanent essential arterial hypertension].
Topics: Adult; Arteries; Arterioles; Benzazepines; Blood Pressure; Dihydralazine; Diltiazem; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Middle Aged; Vascular Resistance; Vasodilator Agents | 1982 |
Baroreflex response and vasodilating drugs in essential hypertension.
Topics: Adult; Benzazepines; Blood Pressure; Brachial Artery; Dihydralazine; Diltiazem; Heart Rate; Humans; Hydralazine; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Pressoreceptors; Reflex; Vascular Resistance | 1983 |
Calcium channel blockers.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Half-Life; Heart Diseases; Humans; Hypertension; Kinetics; Myocardial Infarction; Nifedipine; Perhexiline; Vasodilator Agents; Verapamil | 1983 |
Hemodynamic effects of diltiazem in hypertension.
Topics: Adult; Arteries; Benzazepines; Blood Pressure; Diltiazem; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pressoreceptors; Reflex | 1983 |
Role of calcium antagonists in the treatment of essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Catecholamines; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Vascular Resistance | 1983 |
Therapeutic uses of calcium channel blockers.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiovascular System; Diltiazem; Humans; Hypertension; Infant; Muscle, Smooth; Nifedipine; Tachycardia; Verapamil | 1983 |
Decreased relaxation of isolated mesenteric resistance vessels from 2-kidney, 1 clip Goldblatt hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vascular Resistance | 1983 |
Antihypertensive effect of diltiazem in young or adult rats of genetically hypertensive strains.
Topics: Age Factors; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Female; Hydralazine; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Effects of long-term administration of diltiazem hydrochloride in hypertensive patients.
Topics: Adult; Benzazepines; Blood Chemical Analysis; Blood Pressure; Diltiazem; Electrocardiography; Female; Humans; Hypertension; Liver; Male; Middle Aged | 1983 |
Exaggerated hypotensive responses to calcium antagonists in spontaneously hypertensive rats.
Topics: Action Potentials; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Hypertension; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil | 1983 |
[Calcium antagonists. Concept and therapeutic applications].
Topics: Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Vasospasm; Diltiazem; Humans; Hypertension; Nifedipine | 1982 |
Antihypertensive effect of KB-944, a new calcium antagonist, in conscious normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Diltiazem; Heart Rate; Hypertension; Hypertension, Renal; Nifedipine; Rats; Thiazoles | 1982 |
Development of diltiazem, a calcium antagonist: coronary vasodilating and antihypertensive actions.
Topics: Animals; Antihypertensive Agents; Benzazepines; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Hypertension; Rats | 1982 |
[Dilzem - a new calcium antagonist is introduced].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium Channel Blockers; Coronary Vasospasm; Diltiazem; Heart; Humans; Hypertension; Myocardial Contraction | 1982 |
Diltiazem and contraction in cat ventricular muscle during experimentally induced right ventricular systolic hypertension.
Topics: Animals; Benzazepines; Calcium; Cats; Diltiazem; Hypertension; Myocardial Contraction; Myocardium | 1982 |
Clinical study on the hypotensive effect of diltiazem hydrochloride.
Topics: Adult; Aged; Benzazepines; Blood Pressure; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Trichlormethiazide | 1981 |
Calcium antagonists.
Topics: Angina Pectoris; Calcium Channel Blockers; Cell Membrane; Diltiazem; Heart; Humans; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Infarction; Myocardium; Nifedipine; Perhexiline; Verapamil | 1980 |
[Angina pectoris and hypertension. Dilzem: new alternative to therapy].
Topics: Angina Pectoris; Benzazepines; Calcium Channel Blockers; Diltiazem; Humans; Hypertension | 1981 |
Cardiovascular protection by Ca antagonists.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Coronary Vasospasm; Diltiazem; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Rats; Swine; Verapamil | 1980 |
Thyrotropin-releasing hormone hyperactivity in the preoptic area of spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Calcium Channel Blockers; Diltiazem; Enalapril; Hypertension; Male; Preoptic Area; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thyrotropin-Releasing Hormone; RNA, Messenger; Thyrotropin-Releasing Hormone; Time Factors; Up-Regulation | 1995 |
Calcium channels in vitamin B6 deficiency-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Diltiazem; Hypertension; Male; Nicotinic Acids; Nifedipine; Oxadiazoles; Rats; Rats, Sprague-Dawley; Verapamil; Vitamin B 6 Deficiency | 1993 |
Effect of clentiazem (TA-3090) with posttreatment on neurologic and histologic disorders of stroke-prone spontaneously hypertensive rats with history of stroke.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Brain; Cerebrovascular Disorders; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidney; Nervous System; Rats; Rats, Inbred SHR; Sodium, Dietary | 1994 |
Nicardipine may impair glucose metabolism in hypertensive diabetic patients.
Topics: Adult; Aged; Atenolol; Carteolol; Diabetes Mellitus, Type 2; Diltiazem; Enalapril; Female; Glucose; Glycated Hemoglobin; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nicardipine; Propanolamines | 1994 |
Effect of intravenous calcium antagonists on left ventricular diastolic function in hypertension: assessed by pulsed-Doppler echocardiogram.
Topics: Calcium Channel Blockers; Diastole; Diltiazem; Echocardiography, Doppler, Pulsed; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Ventricular Function, Left | 1995 |
[Reducing hypertension may worsen symptoms of acute apoplexy].
Topics: Acute Disease; Aged; Cerebrovascular Disorders; Diltiazem; Felodipine; Humans; Hypertension; Male; Radionuclide Imaging; Risk Factors | 1995 |
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dibenzothiepins; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nicardipine; Nifedipine; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar | 1993 |
Calcium channel blockade and uncontrolled blood pressure during phaeochromocytoma surgery.
Topics: Aged; Anesthesia, Inhalation; Blood Pressure; Cryosurgery; Diltiazem; Humans; Hypertension; Intraoperative Care; Isoflurane; Liver Neoplasms; Male; Nitroprusside; Pheochromocytoma; Preoperative Care | 1995 |
[The effect of cardil (diltiazem) on thrombocyte aggregation in hypertension].
Topics: Adult; Analysis of Variance; Chronic Disease; Diltiazem; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Time Factors | 1995 |
Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Cholecalciferol; Cholesterol; Coronary Vessels; Diltiazem; Disease Models, Animal; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Risk Factors; Verapamil | 1994 |
Control of systemic hypertension with diltiazem, a calcium-antagonist, in patients with a mildly elevated intracranial pressure: a comparative study.
Topics: Aged; Craniotomy; Diltiazem; Humans; Hypertension; Intracranial Pressure; Middle Aged; Nicardipine; Nitroglycerin; Retrospective Studies | 1994 |
Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women.
Topics: Adult; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diltiazem; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Sex Characteristics | 1994 |
Organic anxiety syndrome after withdrawal of atenolol.
Topics: Aged; Anxiety Disorders; Atenolol; Diltiazem; Humans; Hypertension; Lorazepam; Male; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
[Effects of diltiazem hydrochloride on blood gases].
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anesthesia, General; Blood Pressure; Diltiazem; Female; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Oxygen; Partial Pressure | 1994 |
Erythema multiforme, Stevens-Johnson syndrome, and diltiazem.
Topics: Adult; Animals; Cricetinae; Diltiazem; Erythema Multiforme; Humans; Hypertension; Male; Stevens-Johnson Syndrome | 1993 |
Are all calcium antagonists equally effective for reducing reinfarction rate?
Topics: Adult; Aged; Diltiazem; Humans; Hypertension; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Recurrence; Verapamil | 1993 |
Effects of verapamil and diltiazem on dopamine release in the central nervous system of spontaneously hypertensive rats.
Topics: Animals; Corpus Striatum; Diltiazem; Dopamine; Electric Stimulation; Hypertension; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Verapamil | 1993 |
Effects of semotiadil fumarate, a novel calcium antagonist, on blood pressure and heart rate in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Thiazoles | 1993 |
[Paroxysmal atrial fibrillation and flutter and "occult" arterial hypertension. The importance of the ambulatory monitoring of the blood pressure. Apropos 2 cases].
Topics: Atenolol; Atrial Fibrillation; Atrial Flutter; Blood Pressure Monitors; Diltiazem; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Male; Middle Aged; Verapamil | 1993 |
[Hypotensive effect and characteristics of the effect on the central hemodynamics of the delayed-action form of diltiazem (Dilren) in patients with hypertension].
Topics: Adult; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 1993 |
[Reproducibility of heart rate variability measurements in repeated 24-hour long-term ECG registration].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Diltiazem; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Nifedipine; Reference Values; Reproducibility of Results; Signal Processing, Computer-Assisted | 1993 |
High-performance liquid chromatographic determination of diltiazem and two of its metabolites in plasma using a short alkyl chain silanol deactivated column.
Topics: Chromatography, High Pressure Liquid; Diltiazem; Humans; Hypertension; Indicators and Reagents; Male; Silanes; Spectrophotometry, Ultraviolet | 1993 |
Single-drug therapy for hypertension in men.
Topics: Antihypertensive Agents; Diltiazem; Humans; Hypertension; Male | 1993 |
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
Topics: Anesthesia; Animals; Blood Pressure; Bundle of His; Calcium Channel Blockers; Dibenzothiepins; Diltiazem; Dogs; Electrocardiography; Female; Heart; Heart Conduction System; Heart Rate; Hypertension; In Vitro Techniques; Male; Nifedipine; Piperazines; Rabbits; Verapamil | 1993 |
Role of endothelium in the mechanical response of the carotid arterial wall to calcium blockade in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Animals; Arteries; Calcium Channel Blockers; Carotid Arteries; Compliance; Diltiazem; Endothelium, Vascular; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines | 1993 |
[Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension].
Topics: Anesthesia, Intravenous; Calcium Channel Blockers; Diltiazem; Droperidol; Female; Fentanyl; Humans; Hypertension; Intraoperative Complications; Ketamine; Male; Middle Aged; Nicardipine; Nifedipine | 1993 |
Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists.
Topics: Adult; Cross-Sectional Studies; Cyclosporine; Dental Calculus; Dental Plaque Index; Diltiazem; Drug Interactions; Female; Gingival Hyperplasia; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Models, Dental; Nifedipine; Periodontal Index; Saliva | 1993 |
Effect of diltiazem and methyldopa on gestation-related renal complications in rats with adriamycin nephrosis. Relationship to glomerular prostanoid synthesis.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diltiazem; Doxorubicin; Female; Hypertension; Kidney Diseases; Kidney Glomerulus; Methyldopa; Pregnancy; Pregnancy Complications; Prostaglandins; Proteinuria; Rats; Rats, Wistar | 1995 |
Effects of antihypertensive therapy on platelet cytosolic calcium responses to low density lipoprotein cholesterol.
Topics: Aged; Aged, 80 and over; Blood Platelets; Calcium; Cholesterol, LDL; Cytosol; Diltiazem; Drug Therapy, Combination; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Prospective Studies | 1996 |
Revisiting calcium channel blockers--from basic facts to clinical practice.
Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1996 |
Inhibited neutrophil functions in patients treated with nifedipine but not with verapamil or diltiazem.
Topics: Adult; Calcium; Calcium Channel Blockers; Chemotaxis, Leukocyte; Diltiazem; Humans; Hypertension; Neutrophils; Nifedipine; Phagocytosis; Superoxides; Verapamil | 1996 |
Effects of antihypertensive drugs on blood pressure and metabolic alterations in the fructose-induced hypertensive rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diltiazem; Fructose; Glucose Tolerance Test; Hypertension; Insulin Resistance; Isoquinolines; Kidney Function Tests; Lipids; Male; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Triglycerides | 1996 |
Application of response surface methodology and factorial designs to clinical trials for drug combination development.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Data Interpretation, Statistical; Diltiazem; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Statistics as Topic | 1996 |
Dysautoregulation in patients with hypertensive intracerebral hemorrhage. A SPECT study.
Topics: Adult; Aged; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Diltiazem; Homeostasis; Humans; Hypertension; Middle Aged; Tomography, Emission-Computed, Single-Photon; Trimethaphan | 1995 |
Pharmacological studies on a new antihypertensive agent, S-2150, a benzothiazepine derivative: 2. Hypotensive effects in normotensive and hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channels; Cardiovascular Diseases; Diltiazem; Heart Rate; Hypertension; Hypotension; Kidney Diseases; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Wistar | 1996 |
Insulin sensitivity, glucose effectiveness, and beta-cell function in obese males with essential hypertension: investigation of the effects of treatment with a calcium channel blocker (diltiazem) or an angiotensin-converting enzyme inhibitor (quinapril).
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Glucose Tolerance Test; Humans; Hypertension; Insulin Resistance; Islets of Langerhans; Isoquinolines; Male; Middle Aged; Obesity; Quinapril; Tetrahydroisoquinolines | 1997 |
[Treatment of mild and moderate hypertension with diltiazem 240mg. Brazilian multicenter trial].
Topics: Adolescent; Adult; Aged; Analysis of Variance; Blood Pressure; Diltiazem; Drug Tolerance; Female; Humans; Hypertension; Male; Middle Aged; Time Factors; Treatment Outcome | 1996 |
Lack of effect of a diuretic added to diltiazem.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Data Interpretation, Statistical; Diltiazem; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Research Design; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 1997 |
Clinical features of acute reversible tacrolimus (FK 506) nephrotoxicity in kidney transplant recipients.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Antifungal Agents; Biopsy, Needle; Clarithromycin; Creatinine; Diltiazem; Drug Interactions; Female; Humans; Hyperglycemia; Hyperkalemia; Hypertension; Immunosuppressive Agents; Infusions, Intravenous; Itraconazole; Kidney; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Time Factors; Transplantation, Homologous; Tremor; Ultrasonography; Vasodilator Agents | 1997 |
[The effect of prophylactic intravenous diltiazem drip infusion on myocardial ischemia during noncardiac surgery].
Topics: Aged; Aged, 80 and over; Anesthesia, General; Calcium Channel Blockers; Coronary Disease; Diltiazem; Elective Surgical Procedures; Female; Humans; Hypertension; Infusions, Intravenous; Intraoperative Care; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Premedication; Risk Factors | 1997 |
Diltiazem slow-release and left-ventricular hypertrophy: a volumetric approach of left ventricular mass using magnetic resonance imaging.
Topics: Adult; Aged; Calcium Channel Blockers; Diltiazem; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance | 1997 |
Dopamine and diltiazem-induced natriuresis in the spontaneously hypertensive rat.
Topics: Animals; Benzazepines; Diltiazem; Dopamine; Dopamine Antagonists; Glomerular Filtration Rate; Hypertension; Infusions, Intra-Arterial; Kidney; Kidney Cortex; Kidney Medulla; Natriuresis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine D1; Regression Analysis; Renal Artery; Sodium-Potassium-Exchanging ATPase; Species Specificity | 1997 |
Protective effects of CD-832 on organ damage in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Diltiazem; Heart Rate; Hypertension; Kidney; Male; Myocardium; Niacinamide; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1997 |
Reversal of early metabolic dysfunction in hypertensive rat left-ventricular myocytes by angiotensin-converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Cardiomegaly; Diltiazem; Hypertension; Imidazoles; Imidazolidines; Male; Mitochondria, Heart; Myocardium; Organelles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase | 1997 |
Effect of calcium antagonists on plasma norepinephrine levels, heart rate, and blood pressure.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Drug Administration Routes; Follow-Up Studies; Heart Rate; Humans; Hypertension; MEDLINE; Middle Aged; Norepinephrine; Retrospective Studies; Time Factors; Verapamil | 1997 |
Synthesis and biological activity of novel 2-(alpha-alkoxyimino)benzylpyridine derivatives as K+ channel openers.
Topics: Administration, Oral; Animals; Aorta, Thoracic; Blood Pressure; Coronary Circulation; Cromakalim; Cyclic N-Oxides; Diltiazem; Dogs; Hypertension; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship; Vasodilation; Vasodilator Agents | 1997 |
[Introducing mibefradil--a new T-calcium channel blocker].
Topics: Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Mibefradil; Nifedipine; Tetrahydronaphthalenes | 1997 |
Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension.
Topics: Adult; Aged; Aldosterone; Arteries; Compliance; Diltiazem; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 1997 |
Objectives of high blood pressure treatment: left ventricular hypertrophy, diastolic function, and coronary reserve.
Topics: Antihypertensive Agents; Arterioles; Bisoprolol; Blood Pressure; Coronary Circulation; Diastole; Diltiazem; Disease Progression; Enalapril; Fibrosis; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Treatment Outcome; Ventricular Dysfunction, Left | 1998 |
[Evaluation of the tolerance and effectiveness of Diltiazem LP 300 mg in hypertensive patients with chronic renal insufficiency].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Drug Tolerance; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Treatment Outcome | 1998 |
Pharmacokinetics and hypotensive effect of diltiazem in rabbits: comparison of diltiazem with its major metabolites.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chromatography, High Pressure Liquid; Diltiazem; Dose-Response Relationship, Drug; Female; Hypertension; Injections, Intravenous; Molecular Structure; Rabbits | 1998 |
Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Diltiazem; Disease Models, Animal; Endothelium, Vascular; Hypertension; Isoquinolines; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Treatment Outcome; Vasodilation; Vasodilator Agents | 1999 |
Assessing the responsiveness of a quality-of-life instrument and the measurement of symptom severity in essential hypertension.
Topics: Diltiazem; Humans; Hypertension; Middle Aged; Pilot Projects; Quality of Life; Randomized Controlled Trials as Topic; Surveys and Questionnaires | 1992 |
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Heart Ventricles; Hypertension; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Rats; Rats, Wistar; Survival Analysis | 1999 |
Sustained-release diltiazem overdose.
Topics: Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Overdose; Female; Follow-Up Studies; Humans; Hypertension; Middle Aged | 1999 |
Combined diltiazem and lidocaine reduces cardiovascular responses to tracheal extubation and anesthesia emergence in hypertensive patients.
Topics: Aged; Anesthesia Recovery Period; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Diltiazem; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Orthopedic Procedures; Preanesthetic Medication | 1999 |
Circadian blood pressure changes and cardiac abnormalities in IgA nephropathy.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Diltiazem; Drug Therapy, Combination; Echocardiography; Enalapril; Female; Glomerulonephritis, IGA; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Contraction | 1999 |
Arthralgia associated with calcium-channel blockers.
Topics: Adult; Arthralgia; Calcium Channel Blockers; Diltiazem; Female; Humans; Hypertension; Knee | 2000 |
Assessment of aortic line of elasticity using polynomial regression analysis.
Topics: Aorta; Blood Pressure; Coronary Disease; Data Interpretation, Statistical; Diltiazem; Elasticity; Enalaprilat; Heart Failure; Humans; Hypertension; Regression Analysis; Risk Factors; Vasodilator Agents | 2000 |
Role of insulin in the regulation of membrane fluidity of erythrocytes in essential hypertension: an electron paramagnetic resonance investigation.
Topics: Calcium; Calcium Channel Blockers; Diltiazem; Electron Spin Resonance Spectroscopy; Erythrocytes; Female; Glucose; Humans; Hypertension; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Membrane Fluidity; Middle Aged | 2000 |
Feasibility of using recipients of health promotional newsletters for post-marketing surveillance.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Feasibility Studies; Female; Health Promotion; Health Status; Humans; Hypertension; Male; Multivariate Analysis; Periodicals as Topic; Product Surveillance, Postmarketing; Sampling Studies; Surveys and Questionnaires; United States | 2000 |
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Retrospective Studies | 2000 |
[Comparative evaluation of the action of altiazem PP-180 taken at different time of the day by patients with stage-II hypertension].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Circadian Rhythm; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Time Factors | 2000 |
Is diltiazem as effective as diuretics and beta-blockers in preventing complications from hypertension?
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Humans; Hypertension; Middle Aged; Norway; Randomized Controlled Trials as Topic; Sweden; Treatment Outcome | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Middle Aged | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Myocardial Infarction; Nifedipine | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics; Humans; Hypertension; Middle Aged; Nifedipine | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Middle Aged; Nifedipine | 2000 |
Ambulatory blood pressure profiles in patients treated with once-daily diltiazem extended-release or indapamide alone or in combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Treatment Outcome | 2000 |
A case of lichenoid purpura possibly caused by diltiazem hydrochloride.
Topics: Aged; Antihypertensive Agents; Diagnosis, Differential; Diltiazem; Humans; Hypertension; Leg; Male; Purpura | 2001 |
Effect of methyldopa on renal function in rats with L-NAME-induced hypertension in pregnancy.
Topics: Animals; Arginine; Diltiazem; Drinking; Eating; Female; Hypertension; Kidney; Methyldopa; NG-Nitroarginine Methyl Ester; Nitrates; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar | 2001 |
Simvastatin and atorvastatin enhance hypotensive effect of diltiazem in rats.
Topics: Animals; Antihypertensive Agents; Atorvastatin; Blood Pressure; Diltiazem; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley | 2001 |
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertension; Imidazoles; In Vitro Techniques; Mibefradil; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Vasoconstrictor Agents; Vasodilation | 2002 |
[Assessment of time-dependent effects of long-acting altiazem in patients with hypertension stage II].
Topics: Adult; Aged; Calcium Channel Blockers; Chronotherapy; Delayed-Action Preparations; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Time Factors | 2002 |
Subgroup analysis of the NORDIL trial.
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Treatment Outcome | 2002 |
[Hypotensive effects of diltiazem in DOCA/saline hypertensive rats (author's transl)].
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Desoxycorticosterone; Diltiazem; Drug Combinations; Hypertension; Injections, Intravenous; Male; Norepinephrine; Rats; Renin; Sodium Chloride; Trichlormethiazide | 1979 |
The inhibition of hypertension and the histological changes in SHR treated with diltiazem [proceedings].
Topics: Animals; Benzazepines; Blood Pressure; Diltiazem; Hypertension; Male; Muscle, Smooth, Vascular; Rats | 1979 |
[Hypotensive effects of diltiazem hydrochloride in the normotensive, spontaneously hypertensive and renal hypertensive rats (author's transl)].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Diltiazem; Heart Rate; Hypertension; Hypertension, Renal; Male; Norepinephrine; Rats | 1979 |
Decreased insulin-sensitive Ca2+ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Diltiazem; Gallic Acid; Homeostasis; Hypertension; Insulin; Isoquinolines; Male; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Failure of verapamil and diltiazem to attenuate the pressor response to hypothalamic stimulation: a possible mechanism.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Diltiazem; Electric Stimulation; Female; Hypertension; Hypertension, Renal; Hypothalamus, Posterior; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tyramine; Verapamil | 1992 |
Prophylactic effects of a new 1,5-benzothiazepine calcium antagonist on stroke in salt-loaded stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Disorders; Circadian Rhythm; Diltiazem; Eating; Hypertension; Kidney Cortex; Male; Rats; Rats, Inbred SHR; Sodium Chloride | 1992 |
Carbamazepine neurotoxic reaction after administration of diltiazem.
Topics: Carbamazepine; Diltiazem; Drug Interactions; Epilepsy; Female; Humans; Hypertension; Middle Aged; Nervous System Diseases; Substance Withdrawal Syndrome | 1992 |
[PHARMFIT--a program for the evaluation of digitally collected cardiovascular parameters].
Topics: Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; Humans; Hypertension; Signal Processing, Computer-Assisted; Software | 1992 |
[Are all calcium antagonists alike?].
Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1992 |
[Attenuation of cardiovascular response to laryngoscopy and tracheal intubation with bolus injection of diltiazem].
Topics: Aged; Depression, Chemical; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Surgical Procedures, Operative | 1992 |
Elevated carbamazepine levels associated with diltiazem use.
Topics: Aged; Carbamazepine; Diltiazem; Humans; Hypertension; Male; Seizures | 1992 |
Diltiazem reduces glomerular pressure in spontaneously hypertensive rats.
Topics: Animals; Diltiazem; Glomerular Filtration Rate; Hemodynamics; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Differences of calcium channels in vascular muscle in hypertension.
Topics: Animals; Calcium Channels; Diltiazem; Electrophysiology; Hypertension; Intracellular Membranes; Muscle, Smooth, Vascular; Rats; Reference Values | 1991 |
[Free oxygen radicals in patients with hypertension].
Topics: Adult; Diltiazem; Female; Free Radicals; Humans; Hypertension; Male; Metipranolol | 1991 |
ECG-gated cardiac scan and echocardiographic assessments of left ventricular hypertrophy: reversal by 6-month treatment with diltiazem.
Topics: Aged; Blood Pressure; Cardiomegaly; Diltiazem; Echocardiography; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Tomography, X-Ray Computed | 1990 |
Arterial vasodilator and antihypertensive effects of diltiazem.
Topics: Adult; Antihypertensive Agents; Cyclic GMP; Diltiazem; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Vasodilator Agents | 1990 |
Antihypertensive effect of a novel calcium antagonist, SD-3211, in experimental hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Diuretics; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Thiazoles | 1991 |
Hemodynamic and metabolic effects of intravenous clentiazem in hypertensive patients.
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Vascular Resistance | 1992 |
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol.
Topics: Aged; Breath Tests; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Diltiazem; Erythromycin; Female; Humans; Hydrocortisone; Hydroxylation; Hypertension; Isoenzymes; Liver; Male; Methylation; Middle Aged; Sex Characteristics | 1992 |
Diltiazem and the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Bradycardia; Diltiazem; Female; Humans; Hypertension | 1991 |
Negative inotropic activity of the calcium antagonists isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardium.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Heart Diseases; Humans; Hypertension; Isradipine; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Pyridines; Vasodilation; Verapamil | 1991 |
Beneficial effects of diltiazem on the natural history of hypertensive diabetic cardiomyopathy in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiomyopathies; Collagen; Diabetic Angiopathies; Diltiazem; Female; Heart Rate; Hypertension; Myocardium; Myosins; Organ Size; Rats; Rats, Inbred Strains; Survival Rate | 1991 |
Diltiazem inhibits the spontaneous platelet aggregation in essential hypertension.
Topics: Adult; beta-Thromboglobulin; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
[Effects of diltiazem on hemodynamics, plasma catecholamine and renin activity during exercise in hypertension].
Topics: Adult; Aged; Catecholamines; Diltiazem; Electrocardiography; Exercise; Hemodynamics; Humans; Hypertension; Middle Aged; Renin | 1991 |
Diltiazem-induced psychosis and a possible diltiazem-lithium interaction.
Topics: Aged; Diltiazem; Drug Synergism; Female; Humans; Hypertension; Lithium; Lithium Carbonate; Mood Disorders; Psychoses, Substance-Induced | 1991 |
[Results of the contest "Cardil (diltiazem) in clinical practice"].
Topics: Angina Pectoris; Cardiology; Clinical Competence; Competitive Behavior; Diltiazem; Drug Information Services; Education, Medical, Continuing; Heart Failure; Humans; Hypertension; Periodicals as Topic; USSR | 1991 |
[Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--9. Control of intraoperative hypertension with diltiazem].
Topics: Anesthesia, Intravenous; Diltiazem; Female; Fentanyl; Humans; Hypertension; Intraoperative Complications; Ketamine; Male | 1991 |
Combined use of nifedipine and diltiazem for the treatment of severe hypertension.
Topics: Aged; Diltiazem; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Hypertension; Male; Nifedipine | 1991 |
Heterogeneous interference of nicardipine, verapamil, and diltiazem with forearm arteriolar responsiveness to adrenergic stimulation in hypertensive patients.
Topics: Arterioles; Diltiazem; Female; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Male; Nicardipine; Norepinephrine; Propranolol; Regional Blood Flow; Vasoconstriction; Vasodilation; Verapamil | 1991 |
Diltiazem for hypertension and premature uterine contractions in a renal transplant recipient taking cyclosporin.
Topics: Adult; Cyclosporins; Diltiazem; Female; Humans; Hypertension; Kidney Transplantation; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Multiple; Twins | 1991 |
[Cardil (diltiazem) in the treatment of patients with ischemic heart disease and hypertension].
Topics: Coronary Disease; Diltiazem; Drug Evaluation; Hemodynamics; Humans; Hypertension; Nifedipine; Verapamil | 1990 |
[Comparison of pro-edematous effects of 2 calcium antagonists in bilaterally nephrectomized rats].
Topics: Albumins; Animals; Diltiazem; Edema; Extracellular Space; Hematocrit; Hemodynamics; Hypertension; Male; Nephrectomy; Nicardipine; Rats; Rats, Inbred Strains | 1990 |
Response of isolated perfused heart to ischemia after long-term treatment of spontaneously hypertensive rats with diltiazem.
Topics: Adenine Nucleotides; Animals; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Disease; Diltiazem; Energy Metabolism; Heart; Hypertension; In Vitro Techniques; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Exercise, hypertension, and left ventricular mass.
Topics: Cardiomegaly; Diltiazem; Exercise; Humans; Hypertension; Propranolol | 1990 |
Foridone and other calcium antagonists in the treatment of essential hypertension.
Topics: Antihypertensive Agents; Binding, Competitive; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Hypertension; Myocardium; Nifedipine; Receptors, Nicotinic; Verapamil | 1990 |
Comparison of converting enzyme inhibitor and calcium channel blocker in hypertensive glomerular injury.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Diltiazem; Glomerular Filtration Rate; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Rats; Rats, Inbred Strains; Thiazepines; Triglycerides | 1990 |
Long-term efficacy and safety of sustained-release diltiazem in the treatment of hypertension.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Humans; Hypertension; Male; Time Factors | 1990 |
Humoral factors determining the blood pressure response to converting enzyme inhibition and calcium channel blockade.
Topics: Adult; Aged; Blood Pressure; Captopril; Delayed-Action Preparations; Diltiazem; Epinephrine; Humans; Hypertension; Middle Aged; Norepinephrine; Renin | 1990 |
Effects of a calcium-antagonist on vascular sympathetic nerve activity in salt-dependent hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Depression, Chemical; Diltiazem; Electric Stimulation; Hypertension; In Vitro Techniques; Mesenteric Arteries; Nephrectomy; Norepinephrine; Rats; Rats, Inbred Strains; Sodium, Dietary; Sympathetic Nervous System | 1990 |
Diltiazem-carbamazepine interaction.
Topics: Aged; Angina Pectoris; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Hypertension; Trigeminal Neuralgia | 1990 |
Captopril, but not diltiazem, favorably affects the course of early chronic renal disease in rats.
Topics: Animals; Calcium; Captopril; Diltiazem; Doxorubicin; Hypertension; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Prostaglandins; Proteinuria; Rats; Rats, Inbred Strains | 1990 |
Calcium antagonists inhibit elevated potassium efflux from aorta of aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Hypertension; In Vitro Techniques; Male; Nisoldipine; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Chloride; Vasoconstriction | 1990 |
Effect of long-term diltiazem treatment on central haemodynamics and exercise endurance in essential hypertension.
Topics: Body Weight; Diltiazem; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Physical Endurance; Posture | 1990 |
Effect of calcium antagonists on aortae isolated from normotensive and hypertensive rats: relaxation and calcium influx blockade.
Topics: Animals; Aorta; Calcium; Diltiazem; Female; Hypertension; In Vitro Techniques; Male; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Verapamil | 1990 |
Pathophysiological background for the use of calcium antagonists.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Vascular Resistance; Vasodilator Agents | 1985 |
Increased cardiovascular responses to norepinephrine and calcium antagonists in essential hypertension compared with normotension in humans.
Topics: Adult; Angiotensin II; Calcium Channel Blockers; Diltiazem; Hemodynamics; Humans; Hypertension; Male; Nifedipine; Norepinephrine; Propranolol | 1985 |
Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dose-Response Relationship, Drug; Femoral Artery; Hypertension; Male; Muscle Contraction; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects.
Topics: Acetylcholine; Adult; Angiotensin II; Diltiazem; Humans; Hypertension; Ion Channels; Middle Aged; Renal Artery; Renal Circulation | 1987 |
Effect of calcium antagonists on hypertension and diabetes in new hypertensive diabetic models.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Disease Models, Animal; Female; Glucose Tolerance Test; Heart; Hydralazine; Hypertension; Kidney; Nifedipine; Organ Size; Rats; Rats, Inbred SHR | 1987 |
Antihypertensive and renal vasodilator effect of diltiazem in DOCA-salt hypertensive dog.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Diltiazem; Dogs; Heart Rate; Hypertension; Regional Blood Flow; Renal Circulation; Renin; Vasodilator Agents | 1988 |
Systolic blood pressure response in three subgroups of hypertensives treated with sustained-release diltiazem.
Topics: Adolescent; Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged | 1988 |
[Demographic characteristics and response to antihypertensive treatment. Study using fixed doses of diltiazem].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Diltiazem; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged | 1989 |
[Calcium antagonists vs ACE inhibitors in the treatment of essential arterial hypertension in the aged].
Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Drug Evaluation; Enalapril; Female; Humans; Hypertension; Male; Nifedipine; Verapamil | 1989 |
Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Allopurinol; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Diltiazem; Endothelium, Vascular; Free Radicals; Hypertension; Male; Oxygen; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Xanthine Oxidase | 1989 |
Response of blood pressure, cardiac output, peripheral resistance, and exercise performance to substitution of calcium blocker for beta-blocker plus thiazide diuretic therapy in patients with both systemic hypertension and mild stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Exercise Test; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1989 |
[Calcium antagonists in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
[The use of calcium antagonists for treating hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1989 |
[Changes in cardiac function in early hypertension and the effects of diltiazem].
Topics: Adult; Diastole; Diltiazem; Echocardiography, Doppler; Female; Heart; Humans; Hypertension; Male; Middle Aged | 1989 |
[Hemodynamic effects of the treatment of hypertension with the calcium channel blocker diltiazem].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 1989 |
Endothelin-induced sudden death and the possible involvement of platelet activating factor (PAF).
Topics: Animals; Aspirin; Azepines; Blood Pressure; Death, Sudden; Dexamethasone; Diltiazem; Electrocardiography; Endothelins; Guinea Pigs; Hypertension; Hypotension; Male; Mice; Mice, Inbred ICR; Peptides; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Triazines; Triazoles | 1989 |
Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Catecholamines; Diltiazem; Female; Heart Rate; Humans; Hypertension; Infusions, Intravenous; Male | 1989 |
Comparison of blood pressure response to heat stress in sauna in young hypertensive patients treated with atenolol and diltiazem.
Topics: Adult; Atenolol; Diltiazem; Female; Hemodynamics; Hot Temperature; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Steam Bath; Supination | 1989 |
Effects of ketanserin, verapamil and diltiazem on vascular sympathetic nerve activity in hypertension.
Topics: Animals; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Ketanserin; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Verapamil | 1989 |
[Efficacy of diltiazem in blood pressure increase caused by exertion].
Topics: Aged; Blood Pressure; Diltiazem; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1989 |
Effects of calcium antagonists on hypertension and diastolic function.
Topics: Blood Pressure; Diastole; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nifedipine; Stroke Volume | 1989 |
[Diltiazem VUFB (Diacordin Spofa) in the treatment of arterial hypertension].
Topics: Diltiazem; Female; Humans; Hypertension; Male; Middle Aged | 1989 |
The acute withdrawal of diltiazem and atenolol: a possible challenge to affective stability.
Topics: Adult; Angina Pectoris; Atenolol; Atrial Flutter; Bipolar Disorder; Diltiazem; Female; Humans; Hypertension; Substance Withdrawal Syndrome | 1989 |
Effects of calcium antagonists on membrane fluidity in hypertension--an electron spin resonance study.
Topics: Adult; Animals; Diltiazem; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Female; Humans; Hypertension; Male; Membrane Fluidity; Middle Aged; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Verapamil | 1988 |
Effects of diltiazem (a calcium antagonist) on neurosecretion and vascular responsiveness in hypertension.
Topics: Animals; Diltiazem; Hemodynamics; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nerve Endings; Neurosecretion; Rats; Rats, Inbred SHR; Rats, Wistar | 1985 |
Hemodynamic effects of calcium entry-blocking agents in normal and hypertensive rats and man.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1985 |
[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR].
Topics: Aldosterone; Animals; Aorta; Aortic Diseases; Benzazepines; Cardiomegaly; Diltiazem; Hindlimb; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin | 1985 |
Diltiazem prevents hypertrophy progression, preserves systolic function, and normalises myocardial oxygen utilisation in the spontaneously hypertensive rat.
Topics: Animals; Cardiomegaly; Coronary Circulation; Diltiazem; Heart; Hypertension; In Vitro Techniques; Methyldopa; Myocardium; Myosins; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 1987 |
Effect of long-term treatment with diltiazem on atrial natriuretic peptides in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Diltiazem; Heart Atria; Heart Ventricles; Hypertension; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1988 |
Long-lasting hypotensive and antihypertensive effects of a new 1,5-benzothiazepine calcium antagonist in hypertensive rats and renal hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Diltiazem; Dogs; Electrocardiography; Electrolytes; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Thiazepines | 1988 |
[Significance of brain renin in pathogenesis of hypertension: effect of diltiazem on active and inactive renins in the brain of spontaneously hypertensive rat].
Topics: Animals; Brain Chemistry; Diltiazem; Enzyme Precursors; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin | 1988 |
Immediate and prolonged hemodynamic effects of TA-3090 on spontaneously hypertensive (SHR) and normal Wistar-Kyoto (WKY) rats.
Topics: Animals; Antihypertensive Agents; Diltiazem; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiazepines | 1988 |
Hemodynamic comparison of diltiazem and TA-3090 in spontaneously hypertensive and normal Wistar-Kyoto rats.
Topics: Animals; Cerebrovascular Circulation; Coronary Circulation; Diltiazem; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Thiazepines; Vascular Resistance | 1988 |
[Calcium inhibitors and treatment of arterial hypertension].
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Hypertension; Verapamil | 1988 |
Comparison of the cardiovascular effects of trans-diclofurime with different types of calcium antagonists in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Hemodynamics; Hypertension; Male; Nifedipine; Oximes; Rats; Rats, Inbred SHR; Time Factors; Verapamil | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
Once-daily dosing of sustained-release diltiazem capsules in mild-to-moderate hypertension.
Topics: Adult; Delayed-Action Preparations; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged | 1988 |
Efferent glomerular arteriolar constriction: a possible intrarenal hemodynamic defect in hypertension.
Topics: Animals; Arterioles; Blood Flow Velocity; Blood Pressure; Diltiazem; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction | 1988 |
Effects of low-dose chronic diltiazem treatment on hemodynamic changes in spontaneously hypertensive rats.
Topics: Animals; Cardiac Output; Diltiazem; Hemodynamics; Hypertension; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1988 |
Surveillance study of diltiazem use in black and nonblack angina patients.
Topics: Aged; Angina Pectoris; Black People; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; United States; White People | 1988 |
Comparative diltiazem plasma clearance in normotensive and hypertensive rats.
Topics: Animals; Diltiazem; Hypertension; Infusions, Intravenous; Injections, Intravenous; Liver; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1987 |
Kinetics of pharmacological effect of diltiazem in spontaneous hypertensive rats.
Topics: Animals; Blood Pressure; Diltiazem; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Rats; Rats, Inbred SHR | 1987 |
Calcium channel antagonists--cardiovascular therapy for the eighties?
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1986 |
Augmented vasodepressor and sympathetic responses to intracerebroventricular injections of diltiazem, a calcium channel blocker, in DOCA-salt hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebral Ventricles; Desoxycorticosterone; Diltiazem; Hypertension; Injections, Intravenous; Injections, Intraventricular; Rats; Rats, Inbred Strains; Sodium Chloride; Sympathetic Nervous System | 1986 |
Comparative effects of bepridil and diltiazem on systemic blood pressure and isolated peripheral arteries in spontaneously hypertensive rats.
Topics: Animals; Arteries; Benzazepines; Bepridil; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrrolidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Pyrrolidines; Sinoatrial Node; Verapamil | 1987 |
Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension.
Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Dopamine; Epinephrine; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Norepinephrine; Plasma Volume; Renal Circulation; Renin; Stroke Volume; Time Factors; Vascular Resistance | 1986 |
Effects of diltiazem hydrochloride on cardiovascular response, platelet aggregation and coagulating activity during exercise testing in systemic hypertension.
Topics: Adenosine Diphosphate; Adult; Antithrombin III; Benzazepines; Blood Coagulation; Cardiovascular System; Diltiazem; Exercise Test; Female; Fibrinogen; Heart Rate; Humans; Hypertension; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Renin | 1986 |
[Carbohydrate tolerance and glucose-stimulated insulin secretion in patients treated with diltiazem].
Topics: Adult; Aged; Benzazepines; Blood Glucose; Coronary Disease; Diltiazem; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Secretion; Male; Middle Aged | 1986 |
Decreased intracellular free magnesium in erythrocytes of spontaneously hypertensive rats.
Topics: Animals; Diltiazem; Erythrocytes; Hypertension; Magnesium; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension.
Topics: Administration, Oral; Adult; Age Factors; Aged; Diltiazem; Female; Half-Life; Heart Rate; Humans; Hypertension; Injections, Intravenous; Kinetics; Male; Time Factors | 1987 |
High-performance liquid chromatographic determination of diltiazem and its major metabolites, N-monodemethyldiltiazem and desacetyldiltiazem, in plasma.
Topics: Aged; Biotransformation; Chromatography, High Pressure Liquid; Diltiazem; Humans; Hypertension; Kinetics; Male; Spectrophotometry, Ultraviolet | 1987 |
Long-term treatment of hypertension with the calcium channel blocker diltiazem.
Topics: Diltiazem; Humans; Hypertension; Longitudinal Studies | 1987 |
Long-term renal effects of diltiazem in essential hypertension.
Topics: Blood Pressure; Body Fluids; Body Weight; Diltiazem; Follow-Up Studies; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Male; Sodium | 1987 |
N-monodesmethyldiltiazem is the predominant metabolite of diltiazem in the plasma of young and elderly hypertensives.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biotransformation; Diltiazem; Female; Half-Life; Humans; Hypertension; Kinetics; Male | 1987 |
Effects of diltiazem hydrochloride on the reduction of blood pressure, and cardiac and renal functions in essential hypertensive patients with renal dysfunction.
Topics: Adult; Blood Pressure; Cardiac Volume; Diltiazem; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Renal Circulation; Renin-Angiotensin System; Stroke Volume | 1987 |
Effects of diltiazem alone and combined with mefruside on cardiovascular response at rest and during exercise, carbohydrate metabolism and serum lipoproteins in patients with systemic hypertension.
Topics: Adult; Blood Pressure; Carbohydrate Metabolism; Diltiazem; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Lipoproteins; Male; Mefruside; Middle Aged; Nifedipine; Renin-Angiotensin System | 1987 |
Acute and chronic studies of diltiazem in elderly versus young hypertensive patients.
Topics: Administration, Oral; Adult; Age Factors; Aged; Blood Pressure; Diltiazem; Female; Half-Life; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged | 1987 |
Effect of sodium balance and calcium channel-blocking drugs on plasma aldosterone responses to infusion of angiotensin II in normal subjects and patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Diltiazem; Female; Humans; Hypertension; Infusions, Intravenous; Middle Aged; Nifedipine; Sodium | 1986 |
Enhanced calcium-sensitivity of erythrocytes in hypertension--calcium-induced changes of erythrocyte osmotic fragility in essential hypertension.
Topics: Adult; Calcium; Calmodulin; Diltiazem; Erythrocytes; Female; Humans; Hypertension; Male; Osmotic Fragility; Trifluoperazine; Verapamil | 1986 |
Comparative effects on blood pressure of different calcium-blocking agents.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Verapamil | 1986 |
[Diltiazem in the therapy of arterial hypertension: polygraphic evaluation of left ventricular performance].
Topics: Aged; Benzazepines; Diltiazem; Female; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Systole | 1985 |
[Effect of calcium antagonist (diltiazem) on left ventricular diastolic properties in essential hypertension: a pulsed Doppler echocardiographic study].
Topics: Adult; Aged; Benzazepines; Blood Pressure; Diltiazem; Echocardiography; Female; Heart; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Ultrasonics | 1985 |
Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension.
Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Forearm; Heart Rate; Hemodynamics; Humans; Hypertension; Lower Body Negative Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Posture; Renin; Renin-Angiotensin System; Vascular Resistance | 1985 |
Electrolyte imbalance of cultured vascular smooth muscle cells from SHR, its cause and effect.
Topics: Animals; Aorta; Cells, Cultured; Diltiazem; Electrolytes; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1985 |
Effects of nifedipine and diltiazem on hemodynamic responses at rest and during exercise in hypertensive patients.
Topics: Adult; Aged; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Diltiazem; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nifedipine; Physical Exertion; Rest; Stroke Volume; Vasodilation | 1985 |
[Arrhythmias in the elderly patients: atrial fibrillation].
Topics: Aged; Aging; Atrial Fibrillation; Coronary Disease; Diltiazem; Humans; Hypertension; Mitral Valve Insufficiency; Verapamil | 1985 |
Hemodynamic effects of prolonged treatment with diltiazem in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Benzazepines; Blood Pressure; Diltiazem; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance | 1985 |