diltiazem has been researched along with Heart Disease, Ischemic in 147 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 108 (73.47) | 18.2507 |
2000's | 35 (23.81) | 29.6817 |
2010's | 3 (2.04) | 24.3611 |
2020's | 1 (0.68) | 2.80 |
Authors | Studies |
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Damman, P; de Vos, A; Dimitriu-Leen, A; Elias-Smale, SE; Jansen, TPJ; Konst, RE; Maas, AHEM; Paradies, V; Smits, PC; Teerenstra, S; van den Oord, SCH; van Royen, N | 1 |
Meng, T; Sun, C; Wei, Y | 1 |
Kawasaki, T; Sugihara, H | 1 |
Kane, SA; Lynch, JJ; Regan, CP; Stump, GL | 1 |
Barrios, V | 1 |
Gadzhiev, AN | 1 |
LaRocca, GM; White, WB | 1 |
Beckerman, B; Brennan, C; Bultas, J; Deanfield, JE; Detry, JM; Lichtlen, PR; Sellier, P; Thaulow, E; Young, ST | 1 |
Mazerkina, IA; Pavlova, LI; Svetyĭ, LI | 1 |
Branzi, A; Paoli, G; Rapezzi, C; Vassallo, PL | 1 |
Hirata, Y; Hiroi, Y; Maemura, K; Nagai, R; Nakamura, F; Nakao, T; Ohno, M; Takeda, N; Tsuchiya, N | 1 |
Calabrò, R; Cice, G; D'Andrea, A; D'Isa, S; Di Benedetto, A; Ferrara, L; Iacono, A; Russo, PE | 1 |
Safonova, EV; Samoĭlenko, LE; Sergienko, VB; Zharova, EA | 1 |
Chen, G; Wang, GL; Zhang, P; Zheng, K | 1 |
Chicherina, EN; Malykh, SV | 1 |
Chaitman, BR; Chumakova, G; Kuch, J; Parker, JO; Pepine, CJ; Skettino, SL; Skopal, J; Wang, W; Wolff, AA | 1 |
Hidelaratchi, MD; Pathirana, KD | 1 |
Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V | 1 |
Izumi, T; Kitano, Y; Niwano, S; Sasaki, T | 1 |
Głuszek, J; Kara-Perz, H; Kosicka, T; Perz, S | 1 |
Fu, JH; Li, XZ; Liu, JX; Ma, YL; Shang, XH; Shi, Y; Yan, AG; Yu, Z | 1 |
Li, L; Li, Y; Qiao, H; Wu, L | 1 |
Fiszer, M; Kołaciński, Z; Rechciński, T | 1 |
Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T | 1 |
Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A | 1 |
Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L | 1 |
Buluran, J; Cartier, R; Dagenais, F; Hollmann, C | 1 |
Bullon, P; Lacalle, JR; Machuca, G; Martinez Sahuquillo, A; Rios, JV; Rojas, J; Velasco, E | 1 |
Latour, JG; Provost, P; Rousseau, G | 1 |
Behne, M; Dieterich, HA; Lischke, V; Probst, S | 1 |
Aotsuka, T; Asakura, R; Ashizawa, N; Kobayashi, F; Matsuura, A; Okumura, H | 1 |
Christoph, M; Fasol, R; Hannes, W; Holubarsch, C; Keilich, M; Kulinna, C; Seitelberger, R | 1 |
Campelo, M; Cardoso, J; Coutinho, J; Maciel, MJ; Ramalhao, C; Silva, JC; Simoes, L | 1 |
Hikita, Y; Hori, S; Morita, M; Nakagaki, I; Sasaki, S; Sawada, Y; Takeuchi, A | 1 |
Chen, JG; Fu, WJ; Hou, GX; Xia, JH; Yuan, WJ; Zhao, X; Zhu, HN | 1 |
Daxini, BV; Freedman, SB; Kelly, DT; Noyce, D | 1 |
Biscione, F; Lanza, GA; Manzoli, A; Natale, A; Santarelli, P | 1 |
Ichikawa, H; Yamamoto, F; Yamamoto, H | 1 |
Blaise, G; Dumont, L; Garceau, D; Lepage, G; Tanguay, M | 1 |
Lambert, CR; Pepine, CJ; Raymenants, E | 1 |
Adachi, H; Chang, TH; Mori, N; Okuyama, T; Saito, I | 1 |
Graham, DF; Stewart-Wynne, EG | 1 |
Bourassa, MG; Chaitman, BR; Davies, RF; Day, P; Deanfield, JE; Geller, NL; Goldberg, AD; Knatterud, GL; McMahon, RP; Pepine, CJ | 1 |
Bourassa, MG; Chaitman, BR; Davies, RF; Geller, NL; Knatterud, GL; Pepine, CJ; Pratt, C; Rogers, WJ; Sopko, G; Stone, PH | 1 |
Cunningham, D; Fox, K; Hendry, G; Holdright, D; Hubbard, W; Patel, D; Sutton, G; Thomas, R | 1 |
Hosoki, K; Karasawa, T; Kikuta, C; Yamamoto, T | 1 |
Barrish, JC; Gougoutas, JZ; Grover, G; Hedberg, SA; Malley, MF; Moreland, S; Pudzianowski, AT; Spergel, SH | 1 |
Arsie, P; Branca, D; Roberti, MS; Scutari, G; Simonato, B; Venudo, A | 1 |
Aupetit, JF; Chevrel, G; Faucon, G; Loufoua-Moundanga, J; Omar, S; Timour, Q | 1 |
Christoph, M; Fasol, R; Gleichauf, M; Hannes, W; Keilich, M; Seitelberger, R | 1 |
Abdelmeguid, AE; Feher, JJ | 1 |
Atarashi, K; Furuya, Y; Kobayashi, N; Ohe, Y; Satoh, K; Tachibana, C | 1 |
Buser, GA; Gold, MR; Kim, HJ; Peters, RW | 1 |
Cunningham, D; Fox, KM; Mulcahy, D; Purcell, H; Sparrow, J; Wright, C | 1 |
Ahuja, RC; Kumar, RR; Saran, RK; Sinha, N | 1 |
Davies, GJ; Nadazdin, A | 1 |
Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Gaasch, WH; Padovani, CR; Robinson, KG; Schine, L | 1 |
Diedericks, J; Foëx, P; Goldberg, AH; Hopwood, MB; Sear, JW | 1 |
Taylor, SH | 1 |
Bonnefous, JL; Boulieu, R; du Grès, B; Durand, PG; Estanove, S; Ferry, S; Flamens, C; Hercule, C; Lehot, JJ; Villard, J | 1 |
Andrews, TC; Fenton, T; Gibson, RS; Glasser, SP; MacCallum, G; Shook, TL; Stone, PH; Toyosaki, N; Young, PM | 1 |
Centanni, M; Dessì-Fulgheri, P; Ferretti, GF; Mazzara, D; Pupita, G; Rappelli, A; Rimatori, C; Russo, P | 1 |
Saida, K; Umeda, M | 1 |
Auriemma, F; Ceriello, A; Macciocchi, B; Papa, A; Scaletta Romeo di Santillo, M; Simonelli, P; Vetrano, A | 1 |
Ionov, VA; Siurin, AA | 1 |
Billingham, ME; Bristow, MR; Deisher, TA; Fowler, MB; Ginsburg, R; Hoffman, BB; Narita, H; Zera, P | 1 |
Borzak, S; Fenton, T; Glasser, SP; MacCallum, G; Shook, TL; Stone, PH; Young, PM | 1 |
Antunes, E; Catarino, C; da Silva, N; de Oliveira, M; Ferreira, R; Gracias, R; Prates, AS; Quininha, J; Rato, JA; Serra, J | 1 |
Fasol, R; Hannes, W; Holubarsch, CH; Schindler, M; Schlosser, V; Schumacher, B; Seitelberger, R; Zajonc, H | 1 |
Billman, GE; Hamlin, RL | 1 |
Andrews, TC; Conti, CR; Dyrda, I; Frishman, WH; Geller, NL; Goldstein, S; Hill, JA; Knatterud, GL; McMahon, RP; Morgan, NA; Pepine, CJ; Pratt, CM; Sopko, G; Stone, PH | 1 |
Fukuhiro, Y | 1 |
Hutter, JJ; Nearing, BD; Verrier, RL | 1 |
Dzwonczyk, S; Grover, GJ; Monticello, TM | 1 |
Fujita, M; Konishi, J; Nohara, R; Ogino, M; Okuda, K; Sasayama, S; Tamaki, N | 1 |
Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K | 1 |
Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J; Velasco, E | 1 |
Barclay, KD; Buckley, SJ; Farmer, PS; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK | 1 |
Conti, CR | 2 |
Abiko, Y; Hara, A; Hashizume, H | 1 |
Behling, RW; Dzwonczyk, S; Grover, GJ; Malone, HJ; Sleph, PG | 1 |
Gurbel, PA; Herzog, WR; Serebruany, VL | 1 |
Curry, P; Dens, J; Hagel, H; Melcher, A | 1 |
Killip, T | 1 |
Conti, CR; Davies, RF; Deanfield, J; Forman, S; Geller, N; Goldberg, AD; Knatterud, GL; Pepine, CJ; Pratt, C; Sopko, G | 1 |
Kuraoka, F; Kuroiwa, A; Murasato, Y; Nagamoto, Y; Nakashima, Y; Urabe, T | 2 |
Boulet, AP; Chockalingam, A; Fodor, JG; Langer, A; Nadeau, C; Rakusan, K; Savard, D | 1 |
Barclay, KD; Buckley, SJ; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK | 1 |
Dan, K; Horie, T; Katori, K; Kubo, N; Ohara, G | 1 |
Belousov, IuB; Egorova, NA; Karasev, AV; Sokolov, AV; Tishchenkova, NF; Upnitskiĭ, AA | 1 |
Deedwania, PC; Eff, J; Pool, PE; Thadani, U | 1 |
Kler, TS; Kohli, VM; Malhotra, R; Mehta, Y; Mishra, M; Trehan, N | 1 |
Nagao, T; Sakamoto, K; Yamazaki, J | 1 |
Ciaburri, F; De Rosa, ML; Della Guardia, D; Giordano, A; Melfi, M; Rengo, F | 1 |
Bieska, G; Charlon, V; Kobrin, I; Lindberg, E; Pordy, R | 1 |
Adachi, Y; Akima, M; Fukazawa, M; Kato, T; Koga, T; Kuromaru, O; Suzuki, Y; Tamura, K | 1 |
Matsui, S; Shigenobu, K; Tanaka, H | 1 |
Diab, A; Kirsh, MM; Young, EW | 1 |
Angelini, GD; Ascione, R; Cox, C; Lloyd, CT | 1 |
Corretti, MC; Koretsune, Y; Kusuoka, H; Marban, E | 1 |
Edenbaum, LR; Gurbel, PA; Herzog, WR; Schlossberg, ML; Serebruany, VL | 1 |
Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K | 1 |
Dakik, HA; Farmer, JA; He, ZX; Kleiman, NS; Mahmarian, JJ; Pratt, CM; Verani, MS; Wendt, JA | 1 |
Belovol, AN; Kniaz'kova, II; Tsygankov, AI | 1 |
Campbell, CM; Sykes, J; Thompson, RT; Wisenberg, G | 1 |
Costa, A; García-Guasch, R; Llubià, C; Preciado, MJ; Sust, M; Vidal, F | 1 |
Azuma, A; Ito, K; Kinoshita, N; Maeda, T; Matsumoto, K; Nakagawa, M; Sugihara, H; Taniguchi, Y; Terada, K; Ushijima, Y | 1 |
Brieger, DB; Freedman, SB; Hawkins, R; Rajaratnam, R | 1 |
Koshlia, EV | 1 |
Nagao, T; Sato, R; Yamazaki, J | 1 |
Cleophas, TJ; Daniëls, MC; Hendriks, MG; Holwerda, NJ; Schelling, A; van der Vring, JA; Withagen, PJ | 1 |
Antunes, E; de Luca, IM; de Nucci, G; de Oliveira, CF; Metze, K; Moreno, H; Nathan, LP; Sucupira, M; Zappellini, A; Zatz, R | 1 |
Goto, T; Maeda, K; Ohara, F; Ohkubo, K; Ozaki, T; Seki, J; Sugimoto, T; Yamamoto, N | 1 |
Nagao, T; Nishida, M; Sakamoto, K; Urushidani, T | 1 |
Becker, BF; Möbert, J | 1 |
Ballarotto, C; Meloni, C; Stazi, F | 1 |
Carrier, M; Daly, P; Davies, R; Gudas, V; Kostuk, W; Latter, D; Rivard, M; Sullivan, J; Teo, K; White, M | 1 |
Ikegaki, I; Sasaki, Y; Uchida, T; Yamamoto, Y | 1 |
Adachi, Y; Azuma, A; Hikosaka, T; Ito, K; Katoh, S; Sugihara, H; Yoneyama, S; Zen, K | 1 |
Higuchi, H; Katsumata1, N; Ma, X | 1 |
Ishikawa, M; Koga, K; Nagao, T; Sakamoto, K; Urushidani, T | 1 |
Inagaki, K; Izumi, T; Kihara, Y; Sasayama, S | 1 |
Dwivedi, SK; Gupta, R; Mittal, S; Narain, VS; Puri, VK; Saran, RK | 1 |
de Paula, RS; Gebara, O; Gruppi, C; Moffa, P; Nussbacher, A; Pereira-Barreto, AC; Pierri, H; Pinto, L; Serro-Azul, JB; Wajngarten, M | 1 |
Hamada, K; Nagao, T; Yamazaki, J | 1 |
Chevtchik, O; Grubhofer, G; Hiesmayr, M; Lassnigg, A; Podesser, B; Seitelberger, R; Simon-Kupilik, N; Wild, T; Wutte, M | 1 |
Adachi, Y; Akima, M; Fukazawa, M; Imagawa , JI; Kuromaru, O; Suzuki, Y; Tamura, K | 1 |
Dairaku, Y; Ikeda, Y; Iwamoto, H; Iwatate, M; Kawamura, S; Kimura, M; Maekawa, T; Matsuzaki, M; Mikami, S; Miura, T; Okamura, T; Tatsuno, H | 1 |
Armas, JR; Bullón, P; Jiménez, G; Machuca, G; Rojas, JL | 1 |
Nagao, T; Sakamoto, K; Sato, R; Yamazaki, J | 1 |
Bernecker, O; Hallström, S; Kröner, A; Mallinger, R; Ploner, M; Podesser, BK; Schirnhofer, J; Seitelberger, R | 1 |
Adachi, Y; Fukazawa, M; Hatanaka, T; Suzuki, Y; Tamura, K | 1 |
Abdulatif, AS; El-Medany, AH; Mahgoub, AA | 1 |
Thadani, U | 1 |
Dean, DM; Gervais, PB; Goodman, S; Langer, A; Lee, DS; Lenis, J; Ma, P | 1 |
Krumenacker, M; Roland, E | 1 |
Meluzín, J; Simek, P; Stĕtka, F; Zeman, K | 1 |
Fukamachi, K; Fukumura, F; Kinoshita, K; Kurisu, K; Mitani, A; Nakashima, A; Sakamoto, M; Tokunaga, K; Tsuruhara, Y | 1 |
Das, DK; Engelman, RM; Flack, J; Iyengar, J; Kimura, Y; Rousou, J | 1 |
Chibana, T; Higuchi, M; Itomine, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M; Uezu, K | 1 |
Diedericks, J; Foëx, P; Goldberg, AH; Hopwood, MB | 1 |
Arakawa, K; Handa, K; Ikeda, K; Kawasaki, K; Saeki, Y; Sasaki, J; Umeno, M | 1 |
Kodaira, T; Kurita, A; Maruyama, T; Mizuno, K; Nagayoshi, H; Nakamura, H; Nisioka, T; Sugahara, H; Takase, B; Uehata, A | 1 |
Chesi, G; Reverzani, A | 1 |
Billman, GE | 1 |
12 review(s) available for diltiazem and Heart Disease, Ischemic
Article | Year |
---|---|
Subendocardial ischemia in hypertrophic cardiomyopathy.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cardiomyopathy, Hypertrophic; Diagnostic Imaging; Diltiazem; Echocardiography; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Ischemia; Positron-Emission Tomography; Prognosis; Prospective Studies; Pyrimidinones; Tomography, Emission-Computed, Single-Photon; Verapamil | 2014 |
Chronopharmacology of cardiovascular therapy.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cardiovascular Agents; Catecholamines; Chronotherapy; Circadian Rhythm; Clinical Trials as Topic; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Hemodynamics; Humans; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Sleep; Stroke; Verapamil | 2002 |
[Rationale of the cardioprotective effect of diltiazem].
Topics: Calcium Channel Blockers; Cardiotonic Agents; Diltiazem; Heart Rate; Humans; Life Expectancy; Myocardial Ischemia; Prognosis | 1999 |
[Indications for calcium channel antagonist therapy according to the latest large clinical trials].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Female; Humans; Hypertension; Male; Meta-Analysis as Topic; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Treatment Outcome; Verapamil | 2005 |
Clentiazem and diltiazem preserve endothelium-dependent relaxation following global rat heart ischemia.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium; Male; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1995 |
Usefulness of amlodipine for angina pectoris.
Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic | 1994 |
Re-examining the clinical safety and roles of calcium antagonists in cardiovascular medicine.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Vessels; Diltiazem; Humans; Myocardial Infarction; Myocardial Ischemia; Ventricular Dysfunction; Verapamil | 1996 |
[A new approach to the understanding of the mechanism of ischemia/reperfusion damage in the heart and the effects of anti-ischemic drugs].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Dilazep; Diltiazem; Energy Metabolism; Humans; Lysophosphatidylcholines; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Palmitoylcarnitine; Propranolol; Vasodilator Agents | 1996 |
Nisoldipine CC: clinical experience in ischaemic heart disease.
Topics: Amlodipine; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Myocardial Ischemia; Nisoldipine; Randomized Controlled Trials as Topic | 1997 |
The role of diltiazem in treating hypertension and coronary artery disease: new approaches to preventing first events.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Diltiazem; Humans; Hypertension; Myocardial Ischemia | 1997 |
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes | 1998 |
Clinical profile of nicorandil: an overview of its hemodynamic properties and therapeutic efficacy.
Topics: Diltiazem; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1992 |
50 trial(s) available for diltiazem and Heart Disease, Ischemic
Article | Year |
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Efficacy of Diltiazem to Improve Coronary Vasomotor Dysfunction in ANOCA: The EDIT-CMD Randomized Clinical Trial.
Topics: Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Diltiazem; Humans; Myocardial Ischemia; Predictive Value of Tests; Quality of Life | 2022 |
[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Male; Myocardial Ischemia; Treatment Outcome | 2002 |
Medical treatment of myocardial ischemia in coronary artery disease: effect of drug regime and irregular dosing in the CAPE II trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Coronary Disease; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide; Male; Middle Aged; Myocardial Ischemia | 2002 |
[Efficiency and safety of a long-lasting form of diltiazem in the treatment of hypertensive patients with ischemic heart disease].
Topics: Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Electrocardiography; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Severity of Illness Index | 2002 |
Sustained-release diltiazem reduces myocardial ischemic episodes in end-stage renal disease: a double-blind, randomized, crossover, placebo-controlled trial.
Topics: Aged; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Ischemia; Renal Dialysis; Treatment Outcome | 2003 |
[Cardioprotective effects of diltiazem infusion in the perioperative period in patients undergoing coronary artery bypass grafting with extracorporeal circulation].
Topics: Arrhythmias, Cardiac; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Diltiazem; Hemodynamics; Humans; Isoenzymes; Myocardial Ischemia; Protective Agents; Troponin T | 2003 |
[Drug correction of myocardial ischemia in patients with chronic obstructive bronchitis].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bronchitis, Chronic; Calcium Channel Blockers; Cardiovascular Agents; Diltiazem; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Enalapril; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Time Factors; Treatment Outcome | 2003 |
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial.
Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Physical Exertion; Piperazines; Ranolazine; Survival Analysis | 2004 |
Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome | 1991 |
Clinical assessment of gingival size among patients treated with diltiazem.
Topics: Adult; Aged; Analysis of Variance; Dental Plaque Index; Diltiazem; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Myocardial Ischemia; Periodontal Index; Regression Analysis | 1995 |
[Prevention of myocardial ischemia. Study following aortocoronary bypass operation with the calcium antagonist diltiazem].
Topics: Adult; Aged; Coronary Artery Bypass; Diltiazem; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Postoperative Complications | 1995 |
Effect of peri-operative diltiazem on myocardial ischaemia and function in patients receiving mammary artery grafts.
Topics: Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Heart; Hemodynamics; Humans; Internal Mammary-Coronary Artery Anastomosis; Middle Aged; Myocardial Ischemia; Prospective Studies | 1995 |
Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Nitroglycerin | 1995 |
Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.
Topics: Adult; Aged; Amlodipine; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electrophysiology; Female; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia | 1994 |
Time-series analysis of long-term ambulatory myocardial ischemia: effects of beta-adrenergic and calcium channel blockade.
Topics: Atenolol; Circadian Rhythm; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Fourier Analysis; Heart Rate; Humans; Male; Myocardial Ischemia; Signal Processing, Computer-Assisted; Time Factors | 1995 |
The Asymptomatic Cardiac Ischemia Pilot (ACIP) study: design of a randomized clinical trial, baseline data and implications for a long-term outcome trial.
Topics: Aged; Angina Pectoris; Atenolol; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Research Design; Time Factors; Treatment Outcome; United States | 1994 |
Effects of treatment strategies to suppress ischemia in patients with coronary artery disease: 12-week results of the Asymptomatic Cardiac Ischemia Pilot (ACIP) study.
Topics: Aged; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Time Factors; Treatment Outcome; United States | 1994 |
Comparison of the effect of heparin and aspirin versus aspirin alone on transient myocardial ischemia and in-hospital prognosis in patients with unstable angina.
Topics: Adult; Aged; Angina, Unstable; Aspirin; Chi-Square Distribution; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Nitrates; Prognosis; Single-Blind Method; United Kingdom | 1994 |
Effects of diltiazem on perioperative ischemia, arrhythmias, and myocardial function in patients undergoing elective coronary bypass grafting.
Topics: Arrhythmias, Cardiac; Biomarkers; Coronary Artery Bypass; Creatine Kinase; Diltiazem; Echocardiography, Transesophageal; Electrocardiography, Ambulatory; Female; Hemodynamics; Humans; Isoenzymes; Male; Middle Aged; Monitoring, Intraoperative; Myocardial Ischemia; Nitroglycerin; Postoperative Complications; Troponin; Troponin T | 1994 |
Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial.
Topics: Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia | 1993 |
Investigation of therapeutic mechanisms of atenolol and diltiazem in patients with variable-threshold angina.
Topics: Aged; Angina Pectoris, Variant; Atenolol; Blood Pressure; Coronary Angiography; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitroglycerin; Oxygen Consumption | 1994 |
Usefulness of amlodipine for angina pectoris.
Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic | 1994 |
Subsets of ambulatory myocardial ischemia based on heart rate activity. Circadian distribution and response to anti-ischemic medication. The Angina and Silent Ischemia Study Group (ASIS)
Topics: Circadian Rhythm; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Nifedipine; Propranolol | 1993 |
Ischemia in collateral-dependent myocardium: effects of nifedipine and diltiazem in man.
Topics: Aged; Blood Pressure; Collateral Circulation; Coronary Disease; Diltiazem; Electrocardiography; Exercise Test; Exercise Tolerance; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardium; Nifedipine; Nitroglycerin; Oxygen Consumption | 1993 |
[Treatment of ischemic heart disease in the elderly. Comparison of diltiazem, verapamil and gallopamil].
Topics: Age Factors; Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Diltiazem; Drug Evaluation; Exercise Test; Female; Gallopamil; Humans; Male; Middle Aged; Myocardial Ischemia; Verapamil | 1993 |
Discordance between effects of anti-ischemic therapy on ambulatory ischemia, exercise performance and anginal symptoms in patients with stable angina pectoris. The Angina and Silent Ischemia Study Group (ASIS).
Topics: Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Predictive Value of Tests; Propranolol; Treatment Outcome; Vasodilator Agents | 1993 |
Effects of diltiazem on myocardial ischemia in patients with coronary artery disease.
Topics: Aged; Coronary Disease; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Ultrasonography | 1993 |
Diltiazem provides anti-ischemic and anti-arrhythmic protection in patients undergoing coronary bypass grafting.
Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase; Diltiazem; Electrocardiography, Ambulatory; Female; Humans; Isoenzymes; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Prospective Studies | 1993 |
Comparison of subgroups assigned to medical regimens used to suppress cardiac ischemia (the Asymptomatic Cardiac Ischemia Pilot [ACIP] Study).
Topics: Angina Pectoris; Atenolol; Case-Control Studies; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Exercise Tolerance; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Pilot Projects; Prospective Studies; Time Factors | 1996 |
Steady-state plasma concentrations of diltiazem and its metabolites in patients and healthy volunteers.
Topics: Aged; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Spectrophotometry, Ultraviolet | 1996 |
Asymptomatic Cardiac Ischemia Pilot (ACIP) study two-year follow-up: outcomes of patients randomized to initial strategies of medical therapy versus revascularization.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Atenolol; Calcium Channel Blockers; Cardiopulmonary Bypass; Cardiovascular Diseases; Comorbidity; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Humans; Isosorbide Dinitrate; Life Tables; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome; Vasodilator Agents | 1997 |
Effect of morning versus evening dosing of diltiazem on myocardial ischemia detected by ambulatory electrocardiographic monitoring in chronic stable angina pectoris. Dilacor XR Ambulatory Ischemia Study Group.
Topics: Analysis of Variance; Angina Pectoris; Chronic Disease; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Humans; Myocardial Ischemia; Vasodilator Agents | 1997 |
Cardioprotective effects of diltiazem infusion in the perioperative period.
Topics: Aged; Arrhythmias, Cardiac; Cardiovascular Agents; Coronary Artery Bypass; Diltiazem; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Intraoperative Care; Male; Middle Aged; Monitoring, Intraoperative; Myocardial Ischemia; Nitroglycerin; Vasodilator Agents | 1997 |
Antianginal efficacy over 24 hours and exercise hemodynamic effects of once daily sustained-release 300 mg diltiazem and 240 mg verapamil in stable angina pectoris.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Safety; Treatment Outcome; Vasodilator Agents; Verapamil | 1998 |
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes | 1998 |
Troponin I release and myocardial protection with diltiazem in coronary artery bypass surgery.
Topics: Biomarkers; Cardiovascular Agents; Diltiazem; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Perioperative Care; Troponin I | 1998 |
Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study.
Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Diltiazem; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Pilot Projects; Prospective Studies; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents | 1998 |
[Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery].
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Calcium Channel Blockers; Diabetes Complications; Diltiazem; Double-Blind Method; Elective Surgical Procedures; Etomidate; Female; Fentanyl; Halothane; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Premedication; Treatment Outcome | 1998 |
Attenuation of anti-ischemic efficacy during chronic therapy with nicorandil in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Nicorandil; Time Factors; Verapamil | 1999 |
[The effect of diltiazem on the systemic hemodynamics of patients with heart failure due to ischemic heart disease].
Topics: Adult; Cardiovascular Agents; Diltiazem; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia | 1998 |
Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Resear
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dizziness; Double-Blind Method; Drug Combinations; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Time Factors | 1999 |
Silent ischemic interval on exercise test is a predictor of response to drug therapy: a randomized crossover trial of metoprolol versus diltiazem in stable angina.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Electrocardiography; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Random Allocation | 2001 |
Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Disease; Diltiazem; Diuretics; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Myocardial Ischemia | 2001 |
Diltiazem versus nitroglycerin for myocardial protection following coronary artery bypass grafting as assessed by dobutamine stress echocardiography.
Topics: Adrenergic beta-Agonists; Aged; Coronary Artery Bypass; Diltiazem; Dobutamine; Echocardiography; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Perioperative Care; Prospective Studies; Treatment Outcome; Vasodilator Agents | 2001 |
A comparison between the effects of diltiazem and isosorbide dinitrate on digoxin pharmacodynamics and kinetics in the treatment of patients with chronic ischemic heart failure.
Topics: Analysis of Variance; Digoxin; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Electrolytes; Enzyme Inhibitors; Female; Half-Life; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Vasodilator Agents | 2002 |
Randomized comparison of T-type versus L-type calcium-channel blockade on exercise duration in stable angina: results of the Posicor Reduction of Ischemia During Exercise (PRIDE) trial.
Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Double-Blind Method; Female; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia | 2002 |
Effects of nifedipine and diltiazem on myocardial ischemia in patients with severe stable angina pectoris treated with nitrates and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electrocardiography; Exercise; Exercise Test; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Nitrates | 1992 |
A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease.
Topics: Aged; Apolipoproteins; Diltiazem; Female; Humans; Lipids; Lipoproteins; Male; Middle Aged; Myocardial Ischemia; Niacinamide; Nicorandil; Vasodilator Agents | 1992 |
Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angina Pectoris; Bradykinin; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Single-Blind Method; Thromboxane B2 | 1992 |
Clinical investigation of asymptomatic cardiac ischemia.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Atenolol; Coronary Artery Bypass; Coronary Disease; Diltiazem; Electrocardiography; Humans; Isosorbide Dinitrate; Myocardial Ischemia; Nifedipine; Pilot Projects; Prognosis | 1991 |
87 other study(ies) available for diltiazem and Heart Disease, Ischemic
Article | Year |
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Protective effect of diltiazem on myocardial ischemic rats induced by isoproterenol.
Topics: Animals; Calcium; Cardiotonic Agents; Connexin 43; Diltiazem; Disease Models, Animal; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2018 |
Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Stenosis; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Female; Heart Atria; Hemodynamics; Male; Myocardial Ischemia; Serotonin | 2009 |
Diltiazem in the treatment of hypertension and ischemic heart disease.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Myocardial Ischemia; Risk Factors | 2011 |
Exacerbation of Lambert-Eaton myasthenic syndrome caused by an L-type Ca2+ channel antagonist.
Topics: Aged; Atherectomy, Coronary; Calcium Channel Blockers; Coronary Stenosis; Diltiazem; Disease Progression; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Muscle, Skeletal; Myocardial Ischemia | 2003 |
[Preliminary data on combined assessment of tolerance to exercise, left ventricular contractile function in ischemic heart disease patients taking bradycardic agents].
Topics: Atenolol; Bradycardia; Diltiazem; Electrocardiography; Exercise; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Regional Blood Flow | 2003 |
Exacerbation of symptoms due to diltiazem in a patient with Lambert-Eaton myasthenic myopathic syndrome.
Topics: Aged; Diltiazem; Disease Progression; Electromyography; Follow-Up Studies; Humans; Lambert-Eaton Myasthenic Syndrome; Male; Myocardial Ischemia; Neurologic Examination; Risk Assessment; Severity of Illness Index; Sri Lanka | 2004 |
Two cases of Brugada syndrome associated with spontaneous clinical episodes of coronary vasospasm.
Topics: Acetylcholine; Amlodipine; Calcium Channel Blockers; Cardiovascular Agents; Coronary Vasospasm; Defibrillators, Implantable; Diltiazem; Electric Countershock; Electrocardiography; Fatal Outcome; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Ischemia; Syncope; Ventricular Fibrillation | 2006 |
Cardioprotective effects of diltiazem reevaluated by a novel myocardial ischemic model in Chinese miniature swine.
Topics: Administration, Oral; Animals; Cardiotonic Agents; Coronary Angiography; Diltiazem; Disease Models, Animal; Electrocardiography; Female; Heart; Hemodynamics; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Random Allocation; Superoxide Dismutase; Swine; Swine, Miniature | 2007 |
Cardioprotective effects of the combined use of puerarin and Danshensu on acute ischemic myocardial injury in rats.
Topics: Animals; Cardiotonic Agents; Diltiazem; Dose-Response Relationship, Drug; Drug Combinations; Isoflavones; Lactates; Molecular Conformation; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents | 2007 |
[The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].
Topics: 4-Aminopyridine; Acute Disease; Adrenergic beta-Antagonists; Adult; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Overdose; Drug Therapy, Combination; Epinephrine; Female; Heart Rate; Humans; Hypotension; Myocardial Ischemia; Poisoning; Potassium Channel Blockers; Suicide, Attempted; Tachycardia, Supraventricular; Treatment Outcome; Vasoconstrictor Agents; Verapamil | 2007 |
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Diltiazem; Dogs; Female; Glyburide; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1994 |
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart.
Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea | 1995 |
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil | 1994 |
Sustained myocardial protection by clentiazem (TA-3090) after a 90-minute coronary occlusion and 72 hours of reperfusion in dogs with collateral flow.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Collateral Circulation; Coronary Vessels; Diltiazem; Dogs; Evans Blue; Female; Male; Microspheres; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium | 1993 |
Possible involvement of different mechanisms in sudden death induced by endothelin-1 and big endothelin-1.
Topics: Anesthesia; Animals; Death, Sudden, Cardiac; Diltiazem; Electrocardiography; Endothelin-1; Endothelins; Glycopeptides; Kidney; Lung; Male; Mice; Mice, Inbred ICR; Myocardial Ischemia; Myocardium; Potassium; Protease Inhibitors; Protein Precursors | 1995 |
Diltiazem effects on left ventricular function preliminary results of 12 patients evaluated by calibrated apexcardiogram.
Topics: Depression, Chemical; Diastole; Diltiazem; Female; Humans; Kinetocardiography; Male; Middle Aged; Myocardial Ischemia; Systole; Ventricular Function, Left | 1995 |
Effects of a benzothiazepine calcium blocker on electrolyte alteration in human ischemic and reperfused myocardium.
Topics: Adult; Aged; Calcium; Cardioplegic Solutions; Cardiopulmonary Bypass; Cations; Chlorides; Diltiazem; Electron Probe Microanalysis; Female; Heart; Heart Atria; Humans; Male; Microscopy, Electron, Scanning Transmission; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Organ Size; Potassium; Sodium | 1994 |
[Influence of endothelin-1 on ventricular fibrillation threshold in acute myocardial ischemic rats].
Topics: Animals; Diltiazem; Endothelins; Male; Myocardial Ischemia; Rats; Ventricular Fibrillation | 1994 |
[Diltiazem abolishes the effect of ryanodine in St. Thomas' Hospital cardioplegic solution on the post-ischemic functional recovery].
Topics: Animals; Bicarbonates; Calcium; Calcium Channels; Calcium Chloride; Diltiazem; Heart Arrest, Induced; Magnesium; Male; Models, Cardiovascular; Myocardial Ischemia; Potassium Chloride; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sodium Chloride | 1995 |
Clentiazem, diltiazem, and cold cardioplegia in isolated ischemic rabbit hearts: relation between additive cardioprotection, physicochemical properties, and preservation of myocardial lipid components.
Topics: Animals; Antihypertensive Agents; Cardioplegic Solutions; Cold Temperature; Coronary Circulation; Diltiazem; Lipid Metabolism; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rabbits | 1994 |
Effects of a pyranocoumarin compound isolated from a Chinese medicinal plant on ischemic myocardial dysfunction in anesthetized dogs.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coumarins; Diltiazem; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Hemodynamics; Injections, Intravenous; Male; Myocardial Ischemia; Vascular Resistance | 1994 |
Diltiazem-induced acute parkinsonism.
Topics: Aged; Diltiazem; Humans; Male; Myocardial Ischemia; Parkinson Disease, Secondary | 1994 |
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Calcium Channel Blockers; Dibenzothiepins; Diltiazem; Electrocardiography; Heart Rate; Male; Myocardial Ischemia; Myocardium; Oxygen Consumption; Piperazines; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Drug Design; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1993 |
Effects of diltiazem on the calcium accumulation and ATP synthesis simultaneously sustained by isolated rat heart mitochondria.
Topics: Adenosine Triphosphate; Animals; Calcium; Culture Media; Cytoplasm; Diltiazem; Egtazic Acid; Homeostasis; Mitochondria, Heart; Myocardial Ischemia; Rats; Rats, Wistar; Sodium | 1993 |
Attenuation of the ischaemia-induced fall of electrical ventricular fibrillation threshold by a calcium antagonist, diltiazem.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Electric Stimulation; Female; Male; Myocardial Ischemia; Swine; Ventricular Fibrillation | 1993 |
Effect of low perfusate [Ca2+] and diltiazem on cardiac sarcoplasmic reticulum in myocardial stunning.
Topics: Animals; Calcium; Diltiazem; Heart; Kinetics; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Time Factors | 1994 |
[Comparison between diltiazem and nicardipine used during anesthesia for coronary revascularization].
Topics: Aged; Anesthesia, Inhalation; Depression, Chemical; Diltiazem; Female; Fentanyl; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nicardipine | 1994 |
Ischemically mediated sustained monomorphic ventricular tachycardia. Resolution with anti-ischemic therapy.
Topics: Coronary Angiography; Diltiazem; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Procainamide; Tachycardia, Ventricular | 1993 |
Effects of amlodipine versus diltiazem on morning peak in myocardial ischemic activity in angina pectoris.
Topics: Aged; Amlodipine; Angina Pectoris; Circadian Rhythm; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Ischemia | 1993 |
Protective effects of diltiazem on the mechanical performance of the hypoxic myocardium.
Topics: Animals; Cell Hypoxia; Diltiazem; Electric Stimulation; Male; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Rats; Time Factors; Ventricular Function, Left | 1993 |
Diltiazem and regional left ventricular function during graded coronary constriction and propofol anesthesia in the dog.
Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Diltiazem; Dogs; Heart Rate; Myocardial Contraction; Myocardial Ischemia; Propofol; Stroke Volume; Vascular Resistance; Ventricular Function, Left; Ventricular Pressure | 1993 |
[Plasma concentrations of diltiazem and its metabolites in coronary surgery: relation with preoperative treatment].
Topics: Aged; Blood Pressure; Diltiazem; Extracorporeal Circulation; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Preanesthetic Medication | 1993 |
Improvement of ischemic myocardial dysfunction by nisoldipine in relation to its coronary vasodilating action.
Topics: Animals; Blood Pressure; Coronary Circulation; Diltiazem; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Nifedipine; Nisoldipine; Perfusion; Rabbits; Vasodilator Agents | 1993 |
[The clinical efficacy of diltiazem and the means for enhancing it in treating patients with ischemic heart disease combined with chronic bronchitis].
Topics: Adult; Angina Pectoris; Bronchitis; Chronic Disease; Diltiazem; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Hemodynamics; Humans; Middle Aged; Myocardial Ischemia; Phosphatidylcholines; Respiration | 1993 |
Protective effect of clentiazem against epinephrine-induced cardiac injury in rats.
Topics: Animals; Body Weight; Calcium Channel Blockers; Calcium Channels; Cardiomyopathies; Diltiazem; Endomyocardial Fibrosis; Epinephrine; Heart; Heart Ventricles; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1993 |
The effects of mibefradil, a novel calcium channel antagonist on ventricular arrhythmias induced by myocardial ischemia and programmed electrical stimulation.
Topics: Animals; Arrhythmias, Cardiac; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Heart Ventricles; Mibefradil; Myocardial Ischemia; Tetrahydronaphthalenes; Verapamil | 1996 |
[The experimental study of myocardial protection for warm myocardial ischemia in an isolated rat heart: the effect of a calcium antagonist].
Topics: Animals; Bicarbonates; Calcium Channel Blockers; Calcium Chloride; Cardioplegic Solutions; Diltiazem; Glucose; Heart Arrest, Induced; In Vitro Techniques; Magnesium; Male; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Potassium Chloride; Rats; Rats, Wistar; Sodium Chloride; Tromethamine | 1996 |
Potent antifibrillatory effect of combined blockade of calcium channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to diltiazem.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Electrocardiography; Female; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Serotonin Antagonists; Verapamil | 1996 |
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts.
Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left | 1996 |
Limitation of infarct size with preconditioning and calcium antagonist (diltiazem): difference in 99mTc-PYP uptake in the myocardium.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Myocardial Infarction; Myocardial Ischemia; Radionuclide Imaging; Technetium Tc 99m Pyrophosphate | 1996 |
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine | 1996 |
Evaluation of gingival and periodontal conditions following causal periodontal treatment in patients treated with nifedipine and diltiazem.
Topics: Analysis of Variance; Calcium Channel Blockers; Chi-Square Distribution; Dental Care for Chronically Ill; Dental Plaque Index; Diltiazem; Female; Follow-Up Studies; Gingival Overgrowth; Humans; Male; Myocardial Ischemia; Nifedipine; Outcome Assessment, Health Care; Periodontal Diseases; Periodontal Index; Statistics, Nonparametric | 1996 |
Glyburide-reversible cardioprotective effects of BMS-180448: functional and energetic considerations.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium Channel Blockers; Cardiotonic Agents; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Guanidines; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Phosphocreatine; Potassium Channels; Rats; Rats, Sprague-Dawley | 1997 |
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diltiazem; Enzyme-Linked Immunosorbent Assay; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Prostaglandins; Swine; Thromboxane B2 | 1997 |
Silent myocardial ischemia: some good news.
Topics: Adrenergic beta-Antagonists; Atenolol; Calcium Channel Blockers; Combined Modality Therapy; Coronary Disease; Death, Sudden, Cardiac; Diltiazem; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Vasodilator Agents | 1997 |
Effects of lidocaine and diltiazem on recovery of electrophysiologic activity during partial reperfusion following severe myocardial ischemia in canine hearts.
Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Infusions, Intravenous; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Tachycardia, Ventricular; Treatment Outcome; Vasodilator Agents | 1997 |
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines | 1997 |
[The effect of prophylactic intravenous diltiazem drip infusion on myocardial ischemia during noncardiac surgery].
Topics: Aged; Aged, 80 and over; Anesthesia, General; Calcium Channel Blockers; Coronary Disease; Diltiazem; Elective Surgical Procedures; Female; Humans; Hypertension; Infusions, Intravenous; Intraoperative Care; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Premedication; Risk Factors | 1997 |
[A clinico-pharmacological study of the antianginal and anti-ischemic efficacy of a new drug form of diltiazem with delayed release].
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Physical Exertion; Time Factors | 1997 |
Diltiazem inhibits the late increase in extracellular potassium by maintaining glycolytic ATP synthesis during myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Diltiazem; Extracellular Space; Glycolysis; Guinea Pigs; Heart Function Tests; Hydrogen-Ion Concentration; Male; Myocardial Ischemia; Potassium | 1997 |
Effects of lidocaine and diltiazem on ventricular tachyarrhythmia and dispersion of conduction during severe myocardial ischemia in canine hearts.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Heart Conduction System; Lidocaine; Myocardial Ischemia; Sodium Channel Blockers; Tachycardia, Ventricular | 1997 |
The protective effects of CP-060S on ischaemia- and reperfusion- induced arrhythmias in anaesthetized rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiazoles; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion; Piperidines; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1998 |
Cardioprotective effects of beraprost sodium against experimental ischemia and reperfusion as compared with propranolol and diltiazem.
Topics: Animals; Diltiazem; Epoprostenol; Guinea Pigs; Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Propranolol; Vasodilator Agents | 1998 |
Intravenous diltiazem and acute renal failure after cardiac operations.
Topics: Acute Kidney Injury; Age Factors; Arrhythmias, Cardiac; Calcium Channel Blockers; Cerebrovascular Disorders; Chi-Square Distribution; Coronary Artery Bypass; Coronary Disease; Creatinine; Diltiazem; Female; Humans; Incidence; Infusions, Intravenous; Intraoperative Care; Logistic Models; Male; Middle Aged; Myocardial Ischemia; Odds Ratio; Prevalence; Renal Dialysis; Retrospective Studies; Risk Factors; Stroke Volume; Vasodilator Agents | 1998 |
Mechanism for the cardioprotective effects of the calcium channel blocker clentiazem during ischemia and reperfusion.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Ferrets; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury | 1998 |
Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.
Topics: Animals; Diltiazem; Endothelin-1; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Swine | 1998 |
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea | 1998 |
[The effect of diltiazem on neurohumoral regulatory mechanisms in stenocardia patients].
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Atrial Natriuretic Factor; Calcium Channel Blockers; Diltiazem; Exercise Tolerance; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Neurotransmitter Agents; Renin-Angiotensin System | 1998 |
Noninvasive assessment of pharmaceutical intervention during myocardial ischemia-reperfusion in a canine model using two-dimensional 31P chemical shift imaging.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Drug Evaluation; Energy Metabolism; Female; Gadolinium DTPA; Heart; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardium; Phosphocreatine; Phosphorus Isotopes; Propranolol | 1998 |
Effects of diltiazem on myocardial perfusion abnormalities during exercise in patients with hypertrophic cardiomyopathy.
Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Hypertrophic; Data Interpretation, Statistical; Diltiazem; Female; Heart; Heart Rate; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Myocardial Ischemia; Perfusion; Physical Exertion; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon | 1998 |
Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts.
Topics: Acidosis; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Extracellular Space; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Nifedipine; Phosphocreatine; Potassium; Time Factors; Verapamil | 1999 |
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Heart Ventricles; Hypertension; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Rats; Rats, Wistar; Survival Analysis | 1999 |
Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzyl Alcohol; Benzyl Alcohols; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Hemodynamics; In Vitro Techniques; Ion Transport; Lidocaine; Lymphocytes; Male; Myocardial Infarction; Myocardial Ischemia; Propionates; Propranolol; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; Time Factors; Ventricular Fibrillation | 1999 |
Treatment with l-cis diltiazem before reperfusion reduces infarct size in the ischemic rabbit heart in vivo.
Topics: Anesthesia; Animals; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Heart; Hemodynamics; Isomerism; Male; Myocardial Infarction; Myocardial Ischemia; Rabbits; Reperfusion Injury; Time Factors | 1999 |
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates | 1999 |
An uncommon case of variant angina.
Topics: Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Angiography; Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Ergonovine; Female; Hemodynamics; Humans; Infusions, Intravenous; Middle Aged; Myocardial Ischemia; Nitrates; Prognosis; Shock, Cardiogenic; Tissue Plasminogen Activator; Vasodilator Agents | 1999 |
The Canadian Study of Cardiac Transplantation. Atherosclerosis. Investigators of the CASCADE Study.
Topics: Adult; Antihypertensive Agents; Arteriosclerosis; Aspirin; Cardiovascular Agents; Cyclosporine; Cytomegalovirus Infections; Diltiazem; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Middle Aged; Myocardial Ischemia; Postoperative Care; Postoperative Complications | 1999 |
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiography; Endothelin-1; Enzyme Inhibitors; Heart Ventricles; Macrophages; Male; Microscopy; Myocardial Ischemia; Necrosis; Neutrophils; Nicorandil; Nifedipine; Papillary Muscles; Rabbits; Random Allocation; Vasodilator Agents | 2000 |
[Two cases of microvascular vasospastic angina usefulness of 99mTc-tetrofosmin myocardial SPECT in clinical diagnosis].
Topics: Calcium Channel Blockers; Diltiazem; Female; Heart; Humans; Male; Microvascular Angina; Middle Aged; Myocardial Ischemia; Nicorandil; Organophosphorus Compounds; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vasodilator Agents | 2000 |
Protective effect of diltiazem against ischemia-induced decreases in regional myocardial flow in rat heart.
Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Coronary Circulation; Diltiazem; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections; Male; Microspheres; Myocardial Ischemia; Nifedipine; Rats; Rats, Wistar; Regional Blood Flow; Time Factors | 2000 |
Energy preserving effect of l-cis diltiazem in isolated ischemic and reperfused guinea pig hearts: a 31P-NMR study.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Nifedipine; Phosphocreatine; Phosphorus Isotopes | 2000 |
The cardioprotective effects of a new 1,4-benzothiazepine derivative, JTV519, on ischemia/reperfusion-induced Ca2+ overload in isolated rat hearts.
Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fluorometry; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazepines | 2000 |
Diltiazem ameliorates contractile dysfunction without shortening of action potential duration in ischemic heart of anesthetized dogs.
Topics: Action Potentials; Anesthesia; Animals; Cardiovascular Agents; Diltiazem; Dogs; Female; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion | 2001 |
Effects of CP-060S, a novel cardioprotective drug, in the methacholine-induced ECG change model in rats.
Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Choline; Coronary Vessels; Diltiazem; Electrocardiography; Heart Rate; Infusions, Parenteral; Injections, Intravenous; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasodilator Agents | 2001 |
Ischemic preconditioning attenuates cardiac sympathetic nerve injury via ATP-sensitive potassium channels during myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Desipramine; Dialysis Solutions; Diltiazem; Dogs; Glyburide; Heart; Hemodynamics; Ischemic Preconditioning; Myocardial Ischemia; Nicorandil; Norepinephrine; Potassium Channels; Sympathetic Nervous System; Time Factors | 2001 |
The gingival inflammatory infiltrate in cardiac patients treated with calcium antagonists.
Topics: Analysis of Variance; Calcium Channel Blockers; Case-Control Studies; Chi-Square Distribution; Diltiazem; Female; Gingival Hyperplasia; Gingivitis; Histiocytes; Humans; Immunoenzyme Techniques; Lymphocytes; Male; Myocardial Ischemia; Neutrophil Infiltration; Neutrophils; Nifedipine; Plasma Cells; Statistics, Nonparametric | 2001 |
Differences in protective profiles of diltiazem isomers in ischemic and reperfused guinea pig hearts.
Topics: Animals; Atrial Function, Left; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; Isomerism; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Up-Regulation | 2002 |
Diltiazem during reperfusion preserves high energy phosphates by protection of mitochondrial integrity.
Topics: Adenine Nucleotides; Analysis of Variance; Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Diltiazem; Disease Models, Animal; Female; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Phosphocreatine; Probability; Rabbits; Random Allocation; Reference Values; Reperfusion Injury; Sensitivity and Specificity | 2002 |
The long-lasting anti-anginal effects of CP-060S in a rat model of arginine vasopressin-induced myocardial ischaemia.
Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasoconstrictor Agents | 2002 |
Selective L-type, T-type, and nonspecific calcium-channel blockers for stable angina pectoris.
Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Humans; Mibefradil; Myocardial Ischemia | 2002 |
Effects of diltiazem and noradrenaline on extracellular potassium changes in the globally ischaemic rat heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Diltiazem; Electrophysiology; Myocardial Ischemia; Norepinephrine; Potassium; Rats; Rats, Wistar; Ventricular Function | 1992 |
Moderation of myocardial ischemia reperfusion injury by calcium channel and calmodulin receptor inhibition.
Topics: Animals; Calcium Channels; Calmodulin-Binding Proteins; Coronary Circulation; Creatine Kinase; Diltiazem; Female; Male; Malondialdehyde; Models, Cardiovascular; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Oxygen Consumption; Reperfusion Injury; Swine; Trifluoperazine | 1992 |
Effects of denopamine with or without diltiazem on the ischemic heart of anesthetized dogs.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Diltiazem; Dogs; Ethanolamines; Female; Heart; Hemodynamics; Infusions, Intravenous; Male; Myocardial Ischemia; Regional Blood Flow; Stroke Volume | 1992 |
Canine end-systolic pressure-length relationships: depressed by diltiazem, invalidated by ischemia.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Diltiazem; Dogs; Heart Rate; Myocardial Contraction; Myocardial Ischemia; Stroke Volume; Systole; Vascular Resistance; Ventricular Function, Left; Ventricular Outflow Obstruction | 1992 |
[Silent myocardial ischemia with raised ST tract in 2 octogenarian patients without ischemic cardiopathy].
Topics: Age Factors; Aged; Aged, 80 and over; Angina Pectoris; Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Humans; Male; Myocardial Ischemia | 1992 |
Ro 40-5967, a novel calcium channel antagonist, protects against ventricular fibrillation.
Topics: Animals; Benzimidazoles; Binding Sites; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Disease Susceptibility; Dogs; Dose-Response Relationship, Drug; Heart Rate; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Ventricular Fibrillation; Verapamil | 1992 |