Page last updated: 2024-08-23

diltiazem and Heart Disease, Ischemic

diltiazem has been researched along with Heart Disease, Ischemic in 147 studies

Research

Studies (147)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's108 (73.47)18.2507
2000's35 (23.81)29.6817
2010's3 (2.04)24.3611
2020's1 (0.68)2.80

Authors

AuthorsStudies
Damman, P; de Vos, A; Dimitriu-Leen, A; Elias-Smale, SE; Jansen, TPJ; Konst, RE; Maas, AHEM; Paradies, V; Smits, PC; Teerenstra, S; van den Oord, SCH; van Royen, N1
Meng, T; Sun, C; Wei, Y1
Kawasaki, T; Sugihara, H1
Kane, SA; Lynch, JJ; Regan, CP; Stump, GL1
Barrios, V1
Gadzhiev, AN1
LaRocca, GM; White, WB1
Beckerman, B; Brennan, C; Bultas, J; Deanfield, JE; Detry, JM; Lichtlen, PR; Sellier, P; Thaulow, E; Young, ST1
Mazerkina, IA; Pavlova, LI; Svetyĭ, LI1
Branzi, A; Paoli, G; Rapezzi, C; Vassallo, PL1
Hirata, Y; Hiroi, Y; Maemura, K; Nagai, R; Nakamura, F; Nakao, T; Ohno, M; Takeda, N; Tsuchiya, N1
Calabrò, R; Cice, G; D'Andrea, A; D'Isa, S; Di Benedetto, A; Ferrara, L; Iacono, A; Russo, PE1
Safonova, EV; Samoĭlenko, LE; Sergienko, VB; Zharova, EA1
Chen, G; Wang, GL; Zhang, P; Zheng, K1
Chicherina, EN; Malykh, SV1
Chaitman, BR; Chumakova, G; Kuch, J; Parker, JO; Pepine, CJ; Skettino, SL; Skopal, J; Wang, W; Wolff, AA1
Hidelaratchi, MD; Pathirana, KD1
Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V1
Izumi, T; Kitano, Y; Niwano, S; Sasaki, T1
Głuszek, J; Kara-Perz, H; Kosicka, T; Perz, S1
Fu, JH; Li, XZ; Liu, JX; Ma, YL; Shang, XH; Shi, Y; Yan, AG; Yu, Z1
Li, L; Li, Y; Qiao, H; Wu, L1
Fiszer, M; Kołaciński, Z; Rechciński, T1
Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T1
Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A1
Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L1
Buluran, J; Cartier, R; Dagenais, F; Hollmann, C1
Bullon, P; Lacalle, JR; Machuca, G; Martinez Sahuquillo, A; Rios, JV; Rojas, J; Velasco, E1
Latour, JG; Provost, P; Rousseau, G1
Behne, M; Dieterich, HA; Lischke, V; Probst, S1
Aotsuka, T; Asakura, R; Ashizawa, N; Kobayashi, F; Matsuura, A; Okumura, H1
Christoph, M; Fasol, R; Hannes, W; Holubarsch, C; Keilich, M; Kulinna, C; Seitelberger, R1
Campelo, M; Cardoso, J; Coutinho, J; Maciel, MJ; Ramalhao, C; Silva, JC; Simoes, L1
Hikita, Y; Hori, S; Morita, M; Nakagaki, I; Sasaki, S; Sawada, Y; Takeuchi, A1
Chen, JG; Fu, WJ; Hou, GX; Xia, JH; Yuan, WJ; Zhao, X; Zhu, HN1
Daxini, BV; Freedman, SB; Kelly, DT; Noyce, D1
Biscione, F; Lanza, GA; Manzoli, A; Natale, A; Santarelli, P1
Ichikawa, H; Yamamoto, F; Yamamoto, H1
Blaise, G; Dumont, L; Garceau, D; Lepage, G; Tanguay, M1
Lambert, CR; Pepine, CJ; Raymenants, E1
Adachi, H; Chang, TH; Mori, N; Okuyama, T; Saito, I1
Graham, DF; Stewart-Wynne, EG1
Bourassa, MG; Chaitman, BR; Davies, RF; Day, P; Deanfield, JE; Geller, NL; Goldberg, AD; Knatterud, GL; McMahon, RP; Pepine, CJ1
Bourassa, MG; Chaitman, BR; Davies, RF; Geller, NL; Knatterud, GL; Pepine, CJ; Pratt, C; Rogers, WJ; Sopko, G; Stone, PH1
Cunningham, D; Fox, K; Hendry, G; Holdright, D; Hubbard, W; Patel, D; Sutton, G; Thomas, R1
Hosoki, K; Karasawa, T; Kikuta, C; Yamamoto, T1
Barrish, JC; Gougoutas, JZ; Grover, G; Hedberg, SA; Malley, MF; Moreland, S; Pudzianowski, AT; Spergel, SH1
Arsie, P; Branca, D; Roberti, MS; Scutari, G; Simonato, B; Venudo, A1
Aupetit, JF; Chevrel, G; Faucon, G; Loufoua-Moundanga, J; Omar, S; Timour, Q1
Christoph, M; Fasol, R; Gleichauf, M; Hannes, W; Keilich, M; Seitelberger, R1
Abdelmeguid, AE; Feher, JJ1
Atarashi, K; Furuya, Y; Kobayashi, N; Ohe, Y; Satoh, K; Tachibana, C1
Buser, GA; Gold, MR; Kim, HJ; Peters, RW1
Cunningham, D; Fox, KM; Mulcahy, D; Purcell, H; Sparrow, J; Wright, C1
Ahuja, RC; Kumar, RR; Saran, RK; Sinha, N1
Davies, GJ; Nadazdin, A1
Bing, OH; Brooks, WW; Cicogna, AC; Conrad, CH; Gaasch, WH; Padovani, CR; Robinson, KG; Schine, L1
Diedericks, J; Foëx, P; Goldberg, AH; Hopwood, MB; Sear, JW1
Taylor, SH1
Bonnefous, JL; Boulieu, R; du Grès, B; Durand, PG; Estanove, S; Ferry, S; Flamens, C; Hercule, C; Lehot, JJ; Villard, J1
Andrews, TC; Fenton, T; Gibson, RS; Glasser, SP; MacCallum, G; Shook, TL; Stone, PH; Toyosaki, N; Young, PM1
Centanni, M; Dessì-Fulgheri, P; Ferretti, GF; Mazzara, D; Pupita, G; Rappelli, A; Rimatori, C; Russo, P1
Saida, K; Umeda, M1
Auriemma, F; Ceriello, A; Macciocchi, B; Papa, A; Scaletta Romeo di Santillo, M; Simonelli, P; Vetrano, A1
Ionov, VA; Siurin, AA1
Billingham, ME; Bristow, MR; Deisher, TA; Fowler, MB; Ginsburg, R; Hoffman, BB; Narita, H; Zera, P1
Borzak, S; Fenton, T; Glasser, SP; MacCallum, G; Shook, TL; Stone, PH; Young, PM1
Antunes, E; Catarino, C; da Silva, N; de Oliveira, M; Ferreira, R; Gracias, R; Prates, AS; Quininha, J; Rato, JA; Serra, J1
Fasol, R; Hannes, W; Holubarsch, CH; Schindler, M; Schlosser, V; Schumacher, B; Seitelberger, R; Zajonc, H1
Billman, GE; Hamlin, RL1
Andrews, TC; Conti, CR; Dyrda, I; Frishman, WH; Geller, NL; Goldstein, S; Hill, JA; Knatterud, GL; McMahon, RP; Morgan, NA; Pepine, CJ; Pratt, CM; Sopko, G; Stone, PH1
Fukuhiro, Y1
Hutter, JJ; Nearing, BD; Verrier, RL1
Dzwonczyk, S; Grover, GJ; Monticello, TM1
Fujita, M; Konishi, J; Nohara, R; Ogino, M; Okuda, K; Sasayama, S; Tamaki, N1
Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K1
Bullon, P; Lacalle, JR; Machuca, G; Martinez-Sahuquillo, A; Rios, JV; Rojas, J; Velasco, E1
Barclay, KD; Buckley, SJ; Farmer, PS; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK1
Conti, CR2
Abiko, Y; Hara, A; Hashizume, H1
Behling, RW; Dzwonczyk, S; Grover, GJ; Malone, HJ; Sleph, PG1
Gurbel, PA; Herzog, WR; Serebruany, VL1
Curry, P; Dens, J; Hagel, H; Melcher, A1
Killip, T1
Conti, CR; Davies, RF; Deanfield, J; Forman, S; Geller, N; Goldberg, AD; Knatterud, GL; Pepine, CJ; Pratt, C; Sopko, G1
Kuraoka, F; Kuroiwa, A; Murasato, Y; Nagamoto, Y; Nakashima, Y; Urabe, T2
Boulet, AP; Chockalingam, A; Fodor, JG; Langer, A; Nadeau, C; Rakusan, K; Savard, D1
Barclay, KD; Buckley, SJ; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK1
Dan, K; Horie, T; Katori, K; Kubo, N; Ohara, G1
Belousov, IuB; Egorova, NA; Karasev, AV; Sokolov, AV; Tishchenkova, NF; Upnitskiĭ, AA1
Deedwania, PC; Eff, J; Pool, PE; Thadani, U1
Kler, TS; Kohli, VM; Malhotra, R; Mehta, Y; Mishra, M; Trehan, N1
Nagao, T; Sakamoto, K; Yamazaki, J1
Ciaburri, F; De Rosa, ML; Della Guardia, D; Giordano, A; Melfi, M; Rengo, F1
Bieska, G; Charlon, V; Kobrin, I; Lindberg, E; Pordy, R1
Adachi, Y; Akima, M; Fukazawa, M; Kato, T; Koga, T; Kuromaru, O; Suzuki, Y; Tamura, K1
Matsui, S; Shigenobu, K; Tanaka, H1
Diab, A; Kirsh, MM; Young, EW1
Angelini, GD; Ascione, R; Cox, C; Lloyd, CT1
Corretti, MC; Koretsune, Y; Kusuoka, H; Marban, E1
Edenbaum, LR; Gurbel, PA; Herzog, WR; Schlossberg, ML; Serebruany, VL1
Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K1
Dakik, HA; Farmer, JA; He, ZX; Kleiman, NS; Mahmarian, JJ; Pratt, CM; Verani, MS; Wendt, JA1
Belovol, AN; Kniaz'kova, II; Tsygankov, AI1
Campbell, CM; Sykes, J; Thompson, RT; Wisenberg, G1
Costa, A; García-Guasch, R; Llubià, C; Preciado, MJ; Sust, M; Vidal, F1
Azuma, A; Ito, K; Kinoshita, N; Maeda, T; Matsumoto, K; Nakagawa, M; Sugihara, H; Taniguchi, Y; Terada, K; Ushijima, Y1
Brieger, DB; Freedman, SB; Hawkins, R; Rajaratnam, R1
Koshlia, EV1
Nagao, T; Sato, R; Yamazaki, J1
Cleophas, TJ; Daniëls, MC; Hendriks, MG; Holwerda, NJ; Schelling, A; van der Vring, JA; Withagen, PJ1
Antunes, E; de Luca, IM; de Nucci, G; de Oliveira, CF; Metze, K; Moreno, H; Nathan, LP; Sucupira, M; Zappellini, A; Zatz, R1
Goto, T; Maeda, K; Ohara, F; Ohkubo, K; Ozaki, T; Seki, J; Sugimoto, T; Yamamoto, N1
Nagao, T; Nishida, M; Sakamoto, K; Urushidani, T1
Becker, BF; Möbert, J1
Ballarotto, C; Meloni, C; Stazi, F1
Carrier, M; Daly, P; Davies, R; Gudas, V; Kostuk, W; Latter, D; Rivard, M; Sullivan, J; Teo, K; White, M1
Ikegaki, I; Sasaki, Y; Uchida, T; Yamamoto, Y1
Adachi, Y; Azuma, A; Hikosaka, T; Ito, K; Katoh, S; Sugihara, H; Yoneyama, S; Zen, K1
Higuchi, H; Katsumata1, N; Ma, X1
Ishikawa, M; Koga, K; Nagao, T; Sakamoto, K; Urushidani, T1
Inagaki, K; Izumi, T; Kihara, Y; Sasayama, S1
Dwivedi, SK; Gupta, R; Mittal, S; Narain, VS; Puri, VK; Saran, RK1
de Paula, RS; Gebara, O; Gruppi, C; Moffa, P; Nussbacher, A; Pereira-Barreto, AC; Pierri, H; Pinto, L; Serro-Azul, JB; Wajngarten, M1
Hamada, K; Nagao, T; Yamazaki, J1
Chevtchik, O; Grubhofer, G; Hiesmayr, M; Lassnigg, A; Podesser, B; Seitelberger, R; Simon-Kupilik, N; Wild, T; Wutte, M1
Adachi, Y; Akima, M; Fukazawa, M; Imagawa , JI; Kuromaru, O; Suzuki, Y; Tamura, K1
Dairaku, Y; Ikeda, Y; Iwamoto, H; Iwatate, M; Kawamura, S; Kimura, M; Maekawa, T; Matsuzaki, M; Mikami, S; Miura, T; Okamura, T; Tatsuno, H1
Armas, JR; Bullón, P; Jiménez, G; Machuca, G; Rojas, JL1
Nagao, T; Sakamoto, K; Sato, R; Yamazaki, J1
Bernecker, O; Hallström, S; Kröner, A; Mallinger, R; Ploner, M; Podesser, BK; Schirnhofer, J; Seitelberger, R1
Adachi, Y; Fukazawa, M; Hatanaka, T; Suzuki, Y; Tamura, K1
Abdulatif, AS; El-Medany, AH; Mahgoub, AA1
Thadani, U1
Dean, DM; Gervais, PB; Goodman, S; Langer, A; Lee, DS; Lenis, J; Ma, P1
Krumenacker, M; Roland, E1
Meluzín, J; Simek, P; Stĕtka, F; Zeman, K1
Fukamachi, K; Fukumura, F; Kinoshita, K; Kurisu, K; Mitani, A; Nakashima, A; Sakamoto, M; Tokunaga, K; Tsuruhara, Y1
Das, DK; Engelman, RM; Flack, J; Iyengar, J; Kimura, Y; Rousou, J1
Chibana, T; Higuchi, M; Itomine, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M; Uezu, K1
Diedericks, J; Foëx, P; Goldberg, AH; Hopwood, MB1
Arakawa, K; Handa, K; Ikeda, K; Kawasaki, K; Saeki, Y; Sasaki, J; Umeno, M1
Kodaira, T; Kurita, A; Maruyama, T; Mizuno, K; Nagayoshi, H; Nakamura, H; Nisioka, T; Sugahara, H; Takase, B; Uehata, A1
Chesi, G; Reverzani, A1
Billman, GE1

Reviews

12 review(s) available for diltiazem and Heart Disease, Ischemic

ArticleYear
Subendocardial ischemia in hypertrophic cardiomyopathy.
    Journal of cardiology, 2014, Volume: 63, Issue:2

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Cardiomyopathy, Hypertrophic; Diagnostic Imaging; Diltiazem; Echocardiography; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Ischemia; Positron-Emission Tomography; Prognosis; Prospective Studies; Pyrimidinones; Tomography, Emission-Computed, Single-Photon; Verapamil

2014
Chronopharmacology of cardiovascular therapy.
    Blood pressure monitoring, 2002, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cardiovascular Agents; Catecholamines; Chronotherapy; Circadian Rhythm; Clinical Trials as Topic; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Hemodynamics; Humans; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Sleep; Stroke; Verapamil

2002
[Rationale of the cardioprotective effect of diltiazem].
    Cardiologia (Rome, Italy), 1999, Volume: 44 Suppl 1, Issue:Pt 1

    Topics: Calcium Channel Blockers; Cardiotonic Agents; Diltiazem; Heart Rate; Humans; Life Expectancy; Myocardial Ischemia; Prognosis

1999
[Indications for calcium channel antagonist therapy according to the latest large clinical trials].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Female; Humans; Hypertension; Male; Meta-Analysis as Topic; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Treatment Outcome; Verapamil

2005
Clentiazem and diltiazem preserve endothelium-dependent relaxation following global rat heart ischemia.
    The Canadian journal of cardiology, 1995, Volume: 11, Issue:9

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium; Male; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide; Rats; Rats, Sprague-Dawley

1995
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994
Re-examining the clinical safety and roles of calcium antagonists in cardiovascular medicine.
    The American journal of cardiology, 1996, Nov-07, Volume: 78, Issue:9A

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Vessels; Diltiazem; Humans; Myocardial Infarction; Myocardial Ischemia; Ventricular Dysfunction; Verapamil

1996
[A new approach to the understanding of the mechanism of ischemia/reperfusion damage in the heart and the effects of anti-ischemic drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1996, Volume: 108, Issue:4

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Dilazep; Diltiazem; Energy Metabolism; Humans; Lysophosphatidylcholines; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Palmitoylcarnitine; Propranolol; Vasodilator Agents

1996
Nisoldipine CC: clinical experience in ischaemic heart disease.
    Cardiology, 1997, Volume: 88 Suppl 1

    Topics: Amlodipine; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Myocardial Ischemia; Nisoldipine; Randomized Controlled Trials as Topic

1997
The role of diltiazem in treating hypertension and coronary artery disease: new approaches to preventing first events.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:5

    Topics: Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Diltiazem; Humans; Hypertension; Myocardial Ischemia

1997
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
    Cardiology, 1998, Volume: 89 Suppl 1

    Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes

1998
Clinical profile of nicorandil: an overview of its hemodynamic properties and therapeutic efficacy.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Diltiazem; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents

1992

Trials

50 trial(s) available for diltiazem and Heart Disease, Ischemic

ArticleYear
Efficacy of Diltiazem to Improve Coronary Vasomotor Dysfunction in ANOCA: The EDIT-CMD Randomized Clinical Trial.
    JACC. Cardiovascular imaging, 2022, Volume: 15, Issue:8

    Topics: Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Coronary Vessels; Diltiazem; Humans; Myocardial Ischemia; Predictive Value of Tests; Quality of Life

2022
[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Male; Myocardial Ischemia; Treatment Outcome

2002
Medical treatment of myocardial ischemia in coronary artery disease: effect of drug regime and irregular dosing in the CAPE II trial.
    Journal of the American College of Cardiology, 2002, Sep-04, Volume: 40, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Coronary Disease; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide; Male; Middle Aged; Myocardial Ischemia

2002
[Efficiency and safety of a long-lasting form of diltiazem in the treatment of hypertensive patients with ischemic heart disease].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:8

    Topics: Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Electrocardiography; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Severity of Illness Index

2002
Sustained-release diltiazem reduces myocardial ischemic episodes in end-stage renal disease: a double-blind, randomized, crossover, placebo-controlled trial.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:4

    Topics: Aged; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Ischemia; Renal Dialysis; Treatment Outcome

2003
[Cardioprotective effects of diltiazem infusion in the perioperative period in patients undergoing coronary artery bypass grafting with extracorporeal circulation].
    Zhonghua yi xue za zhi, 2003, Aug-25, Volume: 83, Issue:16

    Topics: Arrhythmias, Cardiac; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Diltiazem; Hemodynamics; Humans; Isoenzymes; Myocardial Ischemia; Protective Agents; Troponin T

2003
[Drug correction of myocardial ischemia in patients with chronic obstructive bronchitis].
    Problemy tuberkuleza i boleznei legkikh, 2003, Issue:11

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bronchitis, Chronic; Calcium Channel Blockers; Cardiovascular Agents; Diltiazem; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Enalapril; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Time Factors; Treatment Outcome

2003
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial.
    JAMA, 2004, Jan-21, Volume: 291, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Physical Exertion; Piperazines; Ranolazine; Survival Analysis

2004
Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 1

    Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome

1991
Clinical assessment of gingival size among patients treated with diltiazem.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1995, Volume: 79, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Dental Plaque Index; Diltiazem; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Myocardial Ischemia; Periodontal Index; Regression Analysis

1995
[Prevention of myocardial ischemia. Study following aortocoronary bypass operation with the calcium antagonist diltiazem].
    Der Anaesthesist, 1995, Volume: 44, Issue:2

    Topics: Adult; Aged; Coronary Artery Bypass; Diltiazem; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Postoperative Complications

1995
Effect of peri-operative diltiazem on myocardial ischaemia and function in patients receiving mammary artery grafts.
    European heart journal, 1995, Volume: 16, Issue:1

    Topics: Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Heart; Hemodynamics; Humans; Internal Mammary-Coronary Artery Anastomosis; Middle Aged; Myocardial Ischemia; Prospective Studies

1995
Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period.
    Journal of the American College of Cardiology, 1995, Volume: 25, Issue:2

    Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Nitroglycerin

1995
Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:4

    Topics: Adult; Aged; Amlodipine; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electrophysiology; Female; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia

1994
Time-series analysis of long-term ambulatory myocardial ischemia: effects of beta-adrenergic and calcium channel blockade.
    American heart journal, 1995, Volume: 129, Issue:4

    Topics: Atenolol; Circadian Rhythm; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Fourier Analysis; Heart Rate; Humans; Male; Myocardial Ischemia; Signal Processing, Computer-Assisted; Time Factors

1995
The Asymptomatic Cardiac Ischemia Pilot (ACIP) study: design of a randomized clinical trial, baseline data and implications for a long-term outcome trial.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:1

    Topics: Aged; Angina Pectoris; Atenolol; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Research Design; Time Factors; Treatment Outcome; United States

1994
Effects of treatment strategies to suppress ischemia in patients with coronary artery disease: 12-week results of the Asymptomatic Cardiac Ischemia Pilot (ACIP) study.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:1

    Topics: Aged; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Time Factors; Treatment Outcome; United States

1994
Comparison of the effect of heparin and aspirin versus aspirin alone on transient myocardial ischemia and in-hospital prognosis in patients with unstable angina.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:1

    Topics: Adult; Aged; Angina, Unstable; Aspirin; Chi-Square Distribution; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Nitrates; Prognosis; Single-Blind Method; United Kingdom

1994
Effects of diltiazem on perioperative ischemia, arrhythmias, and myocardial function in patients undergoing elective coronary bypass grafting.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 107, Issue:3

    Topics: Arrhythmias, Cardiac; Biomarkers; Coronary Artery Bypass; Creatine Kinase; Diltiazem; Echocardiography, Transesophageal; Electrocardiography, Ambulatory; Female; Hemodynamics; Humans; Isoenzymes; Male; Middle Aged; Monitoring, Intraoperative; Myocardial Ischemia; Nitroglycerin; Postoperative Complications; Troponin; Troponin T

1994
Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial.
    International journal of cardiology, 1993, Oct-01, Volume: 41, Issue:3

    Topics: Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia

1993
Investigation of therapeutic mechanisms of atenolol and diltiazem in patients with variable-threshold angina.
    American heart journal, 1994, Volume: 127, Issue:2

    Topics: Aged; Angina Pectoris, Variant; Atenolol; Blood Pressure; Coronary Angiography; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Nitrates; Nitroglycerin; Oxygen Consumption

1994
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994
Subsets of ambulatory myocardial ischemia based on heart rate activity. Circadian distribution and response to anti-ischemic medication. The Angina and Silent Ischemia Study Group (ASIS)
    Circulation, 1993, Volume: 88, Issue:1

    Topics: Circadian Rhythm; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Nifedipine; Propranolol

1993
Ischemia in collateral-dependent myocardium: effects of nifedipine and diltiazem in man.
    American heart journal, 1993, Volume: 126, Issue:1

    Topics: Aged; Blood Pressure; Collateral Circulation; Coronary Disease; Diltiazem; Electrocardiography; Exercise Test; Exercise Tolerance; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardium; Nifedipine; Nitroglycerin; Oxygen Consumption

1993
[Treatment of ischemic heart disease in the elderly. Comparison of diltiazem, verapamil and gallopamil].
    Minerva cardioangiologica, 1993, Volume: 41, Issue:5

    Topics: Age Factors; Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Diltiazem; Drug Evaluation; Exercise Test; Female; Gallopamil; Humans; Male; Middle Aged; Myocardial Ischemia; Verapamil

1993
Discordance between effects of anti-ischemic therapy on ambulatory ischemia, exercise performance and anginal symptoms in patients with stable angina pectoris. The Angina and Silent Ischemia Study Group (ASIS).
    Journal of the American College of Cardiology, 1993, Volume: 21, Issue:7

    Topics: Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Predictive Value of Tests; Propranolol; Treatment Outcome; Vasodilator Agents

1993
Effects of diltiazem on myocardial ischemia in patients with coronary artery disease.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1993, Volume: 12, Issue:3

    Topics: Aged; Coronary Disease; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Ultrasonography

1993
Diltiazem provides anti-ischemic and anti-arrhythmic protection in patients undergoing coronary bypass grafting.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1993, Volume: 7, Issue:5

    Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase; Diltiazem; Electrocardiography, Ambulatory; Female; Humans; Isoenzymes; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Prospective Studies

1993
Comparison of subgroups assigned to medical regimens used to suppress cardiac ischemia (the Asymptomatic Cardiac Ischemia Pilot [ACIP] Study).
    The American journal of cardiology, 1996, Jun-15, Volume: 77, Issue:15

    Topics: Angina Pectoris; Atenolol; Case-Control Studies; Delayed-Action Preparations; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Exercise Tolerance; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Pilot Projects; Prospective Studies; Time Factors

1996
Steady-state plasma concentrations of diltiazem and its metabolites in patients and healthy volunteers.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:1

    Topics: Aged; Biotransformation; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Spectrophotometry, Ultraviolet

1996
Asymptomatic Cardiac Ischemia Pilot (ACIP) study two-year follow-up: outcomes of patients randomized to initial strategies of medical therapy versus revascularization.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Atenolol; Calcium Channel Blockers; Cardiopulmonary Bypass; Cardiovascular Diseases; Comorbidity; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Humans; Isosorbide Dinitrate; Life Tables; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome; Vasodilator Agents

1997
Effect of morning versus evening dosing of diltiazem on myocardial ischemia detected by ambulatory electrocardiographic monitoring in chronic stable angina pectoris. Dilacor XR Ambulatory Ischemia Study Group.
    The American journal of cardiology, 1997, Aug-15, Volume: 80, Issue:4

    Topics: Analysis of Variance; Angina Pectoris; Chronic Disease; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Humans; Myocardial Ischemia; Vasodilator Agents

1997
Cardioprotective effects of diltiazem infusion in the perioperative period.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1997, Volume: 12, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; Cardiovascular Agents; Coronary Artery Bypass; Diltiazem; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Intraoperative Care; Male; Middle Aged; Monitoring, Intraoperative; Myocardial Ischemia; Nitroglycerin; Vasodilator Agents

1997
Antianginal efficacy over 24 hours and exercise hemodynamic effects of once daily sustained-release 300 mg diltiazem and 240 mg verapamil in stable angina pectoris.
    International journal of cardiology, 1998, Jan-05, Volume: 63, Issue:1

    Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Safety; Treatment Outcome; Vasodilator Agents; Verapamil

1998
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
    Cardiology, 1998, Volume: 89 Suppl 1

    Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes

1998
Troponin I release and myocardial protection with diltiazem in coronary artery bypass surgery.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1998, Volume: 13, Issue:6

    Topics: Biomarkers; Cardiovascular Agents; Diltiazem; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Perioperative Care; Troponin I

1998
Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study.
    Circulation, 1998, Nov-10, Volume: 98, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Diltiazem; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Pilot Projects; Prospective Studies; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

1998
[Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery].
    Revista espanola de anestesiologia y reanimacion, 1998, Volume: 45, Issue:10

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Calcium Channel Blockers; Diabetes Complications; Diltiazem; Double-Blind Method; Elective Surgical Procedures; Etomidate; Female; Fentanyl; Halothane; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Premedication; Treatment Outcome

1998
Attenuation of anti-ischemic efficacy during chronic therapy with nicorandil in patients with stable angina pectoris.
    The American journal of cardiology, 1999, Apr-01, Volume: 83, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Nicorandil; Time Factors; Verapamil

1999
[The effect of diltiazem on the systemic hemodynamics of patients with heart failure due to ischemic heart disease].
    Likars'ka sprava, 1998, Issue:8

    Topics: Adult; Cardiovascular Agents; Diltiazem; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia

1998
Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Resear
    Angiology, 1999, Volume: 50, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dizziness; Double-Blind Method; Drug Combinations; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Time Factors

1999
Silent ischemic interval on exercise test is a predictor of response to drug therapy: a randomized crossover trial of metoprolol versus diltiazem in stable angina.
    Clinical cardiology, 2001, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Electrocardiography; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Random Allocation

2001
Effects of chlorthalidone and diltiazem on myocardial ischemia in elderly patients with hypertension and coronary artery disease.
    Arquivos brasileiros de cardiologia, 2001, Volume: 76, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Disease; Diltiazem; Diuretics; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Myocardial Ischemia

2001
Diltiazem versus nitroglycerin for myocardial protection following coronary artery bypass grafting as assessed by dobutamine stress echocardiography.
    Wiener klinische Wochenschrift, 2001, Jun-15, Volume: 113, Issue:11-12

    Topics: Adrenergic beta-Agonists; Aged; Coronary Artery Bypass; Diltiazem; Dobutamine; Echocardiography; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Perioperative Care; Prospective Studies; Treatment Outcome; Vasodilator Agents

2001
A comparison between the effects of diltiazem and isosorbide dinitrate on digoxin pharmacodynamics and kinetics in the treatment of patients with chronic ischemic heart failure.
    Saudi medical journal, 2002, Volume: 23, Issue:6

    Topics: Analysis of Variance; Digoxin; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Electrolytes; Enzyme Inhibitors; Female; Half-Life; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Vasodilator Agents

2002
Randomized comparison of T-type versus L-type calcium-channel blockade on exercise duration in stable angina: results of the Posicor Reduction of Ischemia During Exercise (PRIDE) trial.
    American heart journal, 2002, Volume: 144, Issue:1

    Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Double-Blind Method; Female; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia

2002
Effects of nifedipine and diltiazem on myocardial ischemia in patients with severe stable angina pectoris treated with nitrates and beta-blockers.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Electrocardiography; Exercise; Exercise Test; Humans; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Nitrates

1992
A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:5

    Topics: Aged; Apolipoproteins; Diltiazem; Female; Humans; Lipids; Lipoproteins; Male; Middle Aged; Myocardial Ischemia; Niacinamide; Nicorandil; Vasodilator Agents

1992
Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism.
    International journal of cardiology, 1992, Volume: 37, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angina Pectoris; Bradykinin; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Single-Blind Method; Thromboxane B2

1992
Clinical investigation of asymptomatic cardiac ischemia.
    Clinical cardiology, 1991, Volume: 14, Issue:12

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Atenolol; Coronary Artery Bypass; Coronary Disease; Diltiazem; Electrocardiography; Humans; Isosorbide Dinitrate; Myocardial Ischemia; Nifedipine; Pilot Projects; Prognosis

1991

Other Studies

87 other study(ies) available for diltiazem and Heart Disease, Ischemic

ArticleYear
Protective effect of diltiazem on myocardial ischemic rats induced by isoproterenol.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Animals; Calcium; Cardiotonic Agents; Connexin 43; Diltiazem; Disease Models, Animal; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1

2018
Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Stenosis; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Female; Heart Atria; Hemodynamics; Male; Myocardial Ischemia; Serotonin

2009
Diltiazem in the treatment of hypertension and ischemic heart disease.
    Expert review of cardiovascular therapy, 2011, Volume: 9, Issue:11

    Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Myocardial Ischemia; Risk Factors

2011
Exacerbation of Lambert-Eaton myasthenic syndrome caused by an L-type Ca2+ channel antagonist.
    Japanese heart journal, 2003, Volume: 44, Issue:1

    Topics: Aged; Atherectomy, Coronary; Calcium Channel Blockers; Coronary Stenosis; Diltiazem; Disease Progression; Female; Humans; Lambert-Eaton Myasthenic Syndrome; Muscle, Skeletal; Myocardial Ischemia

2003
[Preliminary data on combined assessment of tolerance to exercise, left ventricular contractile function in ischemic heart disease patients taking bradycardic agents].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:4

    Topics: Atenolol; Bradycardia; Diltiazem; Electrocardiography; Exercise; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Regional Blood Flow

2003
Exacerbation of symptoms due to diltiazem in a patient with Lambert-Eaton myasthenic myopathic syndrome.
    The Ceylon medical journal, 2004, Volume: 49, Issue:4

    Topics: Aged; Diltiazem; Disease Progression; Electromyography; Follow-Up Studies; Humans; Lambert-Eaton Myasthenic Syndrome; Male; Myocardial Ischemia; Neurologic Examination; Risk Assessment; Severity of Illness Index; Sri Lanka

2004
Two cases of Brugada syndrome associated with spontaneous clinical episodes of coronary vasospasm.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2

    Topics: Acetylcholine; Amlodipine; Calcium Channel Blockers; Cardiovascular Agents; Coronary Vasospasm; Defibrillators, Implantable; Diltiazem; Electric Countershock; Electrocardiography; Fatal Outcome; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Ischemia; Syncope; Ventricular Fibrillation

2006
Cardioprotective effects of diltiazem reevaluated by a novel myocardial ischemic model in Chinese miniature swine.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:1

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Coronary Angiography; Diltiazem; Disease Models, Animal; Electrocardiography; Female; Heart; Hemodynamics; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Random Allocation; Superoxide Dismutase; Swine; Swine, Miniature

2007
Cardioprotective effects of the combined use of puerarin and Danshensu on acute ischemic myocardial injury in rats.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:8

    Topics: Animals; Cardiotonic Agents; Diltiazem; Dose-Response Relationship, Drug; Drug Combinations; Isoflavones; Lactates; Molecular Conformation; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Time Factors; Vasodilator Agents

2007
[The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].
    Przeglad lekarski, 2007, Volume: 64, Issue:4-5

    Topics: 4-Aminopyridine; Acute Disease; Adrenergic beta-Antagonists; Adult; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Overdose; Drug Therapy, Combination; Epinephrine; Female; Heart Rate; Humans; Hypotension; Myocardial Ischemia; Poisoning; Potassium Channel Blockers; Suicide, Attempted; Tachycardia, Supraventricular; Treatment Outcome; Vasoconstrictor Agents; Verapamil

2007
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:3

    Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Diltiazem; Dogs; Female; Glyburide; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents

1994
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart.
    Cardiovascular research, 1995, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea

1995
Protective effect of some calcium antagonists against mitochondrial calcium injury.
    International journal of tissue reactions, 1994, Volume: 16, Issue:5-6

    Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil

1994
Sustained myocardial protection by clentiazem (TA-3090) after a 90-minute coronary occlusion and 72 hours of reperfusion in dogs with collateral flow.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Collateral Circulation; Coronary Vessels; Diltiazem; Dogs; Evans Blue; Female; Male; Microspheres; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium

1993
Possible involvement of different mechanisms in sudden death induced by endothelin-1 and big endothelin-1.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:1

    Topics: Anesthesia; Animals; Death, Sudden, Cardiac; Diltiazem; Electrocardiography; Endothelin-1; Endothelins; Glycopeptides; Kidney; Lung; Male; Mice; Mice, Inbred ICR; Myocardial Ischemia; Myocardium; Potassium; Protease Inhibitors; Protein Precursors

1995
Diltiazem effects on left ventricular function preliminary results of 12 patients evaluated by calibrated apexcardiogram.
    Acta cardiologica, 1995, Volume: 50, Issue:1

    Topics: Depression, Chemical; Diastole; Diltiazem; Female; Humans; Kinetocardiography; Male; Middle Aged; Myocardial Ischemia; Systole; Ventricular Function, Left

1995
Effects of a benzothiazepine calcium blocker on electrolyte alteration in human ischemic and reperfused myocardium.
    Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:8

    Topics: Adult; Aged; Calcium; Cardioplegic Solutions; Cardiopulmonary Bypass; Cations; Chlorides; Diltiazem; Electron Probe Microanalysis; Female; Heart; Heart Atria; Humans; Male; Microscopy, Electron, Scanning Transmission; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Organ Size; Potassium; Sodium

1994
[Influence of endothelin-1 on ventricular fibrillation threshold in acute myocardial ischemic rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:4

    Topics: Animals; Diltiazem; Endothelins; Male; Myocardial Ischemia; Rats; Ventricular Fibrillation

1994
[Diltiazem abolishes the effect of ryanodine in St. Thomas' Hospital cardioplegic solution on the post-ischemic functional recovery].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1995, Volume: 43, Issue:1

    Topics: Animals; Bicarbonates; Calcium; Calcium Channels; Calcium Chloride; Diltiazem; Heart Arrest, Induced; Magnesium; Male; Models, Cardiovascular; Myocardial Ischemia; Potassium Chloride; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sodium Chloride

1995
Clentiazem, diltiazem, and cold cardioplegia in isolated ischemic rabbit hearts: relation between additive cardioprotection, physicochemical properties, and preservation of myocardial lipid components.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:6

    Topics: Animals; Antihypertensive Agents; Cardioplegic Solutions; Cold Temperature; Coronary Circulation; Diltiazem; Lipid Metabolism; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rabbits

1994
Effects of a pyranocoumarin compound isolated from a Chinese medicinal plant on ischemic myocardial dysfunction in anesthetized dogs.
    European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coumarins; Diltiazem; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Hemodynamics; Injections, Intravenous; Male; Myocardial Ischemia; Vascular Resistance

1994
Diltiazem-induced acute parkinsonism.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:1

    Topics: Aged; Diltiazem; Humans; Male; Myocardial Ischemia; Parkinson Disease, Secondary

1994
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Calcium Channel Blockers; Dibenzothiepins; Diltiazem; Electrocardiography; Heart Rate; Male; Myocardial Ischemia; Myocardium; Oxygen Consumption; Piperazines; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents

1994
Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.
    Bioorganic & medicinal chemistry, 1993, Volume: 1, Issue:4

    Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Drug Design; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993
Effects of diltiazem on the calcium accumulation and ATP synthesis simultaneously sustained by isolated rat heart mitochondria.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1993, Volume: 105, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Culture Media; Cytoplasm; Diltiazem; Egtazic Acid; Homeostasis; Mitochondria, Heart; Myocardial Ischemia; Rats; Rats, Wistar; Sodium

1993
Attenuation of the ischaemia-induced fall of electrical ventricular fibrillation threshold by a calcium antagonist, diltiazem.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:5

    Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Electric Stimulation; Female; Male; Myocardial Ischemia; Swine; Ventricular Fibrillation

1993
Effect of low perfusate [Ca2+] and diltiazem on cardiac sarcoplasmic reticulum in myocardial stunning.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Animals; Calcium; Diltiazem; Heart; Kinetics; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Time Factors

1994
[Comparison between diltiazem and nicardipine used during anesthesia for coronary revascularization].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Depression, Chemical; Diltiazem; Female; Fentanyl; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nicardipine

1994
Ischemically mediated sustained monomorphic ventricular tachycardia. Resolution with anti-ischemic therapy.
    Chest, 1993, Volume: 104, Issue:5

    Topics: Coronary Angiography; Diltiazem; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Procainamide; Tachycardia, Ventricular

1993
Effects of amlodipine versus diltiazem on morning peak in myocardial ischemic activity in angina pectoris.
    The American journal of cardiology, 1993, Nov-15, Volume: 72, Issue:15

    Topics: Aged; Amlodipine; Angina Pectoris; Circadian Rhythm; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Ischemia

1993
Protective effects of diltiazem on the mechanical performance of the hypoxic myocardium.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1993, Volume: 26, Issue:8

    Topics: Animals; Cell Hypoxia; Diltiazem; Electric Stimulation; Male; Myocardial Contraction; Myocardial Ischemia; Papillary Muscles; Rats; Time Factors; Ventricular Function, Left

1993
Diltiazem and regional left ventricular function during graded coronary constriction and propofol anesthesia in the dog.
    Journal of cardiothoracic and vascular anesthesia, 1993, Volume: 7, Issue:6

    Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Diltiazem; Dogs; Heart Rate; Myocardial Contraction; Myocardial Ischemia; Propofol; Stroke Volume; Vascular Resistance; Ventricular Function, Left; Ventricular Pressure

1993
[Plasma concentrations of diltiazem and its metabolites in coronary surgery: relation with preoperative treatment].
    Annales francaises d'anesthesie et de reanimation, 1993, Volume: 12, Issue:5

    Topics: Aged; Blood Pressure; Diltiazem; Extracorporeal Circulation; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Preanesthetic Medication

1993
Improvement of ischemic myocardial dysfunction by nisoldipine in relation to its coronary vasodilating action.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Diltiazem; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Nifedipine; Nisoldipine; Perfusion; Rabbits; Vasodilator Agents

1993
[The clinical efficacy of diltiazem and the means for enhancing it in treating patients with ischemic heart disease combined with chronic bronchitis].
    Kardiologiia, 1993, Volume: 33, Issue:3

    Topics: Adult; Angina Pectoris; Bronchitis; Chronic Disease; Diltiazem; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Hemodynamics; Humans; Middle Aged; Myocardial Ischemia; Phosphatidylcholines; Respiration

1993
Protective effect of clentiazem against epinephrine-induced cardiac injury in rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1

    Topics: Animals; Body Weight; Calcium Channel Blockers; Calcium Channels; Cardiomyopathies; Diltiazem; Endomyocardial Fibrosis; Epinephrine; Heart; Heart Ventricles; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1993
The effects of mibefradil, a novel calcium channel antagonist on ventricular arrhythmias induced by myocardial ischemia and programmed electrical stimulation.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Heart Ventricles; Mibefradil; Myocardial Ischemia; Tetrahydronaphthalenes; Verapamil

1996
[The experimental study of myocardial protection for warm myocardial ischemia in an isolated rat heart: the effect of a calcium antagonist].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1996, Volume: 44, Issue:2

    Topics: Animals; Bicarbonates; Calcium Channel Blockers; Calcium Chloride; Cardioplegic Solutions; Diltiazem; Glucose; Heart Arrest, Induced; In Vitro Techniques; Magnesium; Male; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Potassium Chloride; Rats; Rats, Wistar; Sodium Chloride; Tromethamine

1996
Potent antifibrillatory effect of combined blockade of calcium channels and 5-HT2 receptors with nexopamil during myocardial ischemia and reperfusion in dogs: comparison to diltiazem.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Electrocardiography; Female; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Serotonin Antagonists; Verapamil

1996
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left

1996
Limitation of infarct size with preconditioning and calcium antagonist (diltiazem): difference in 99mTc-PYP uptake in the myocardium.
    Annals of nuclear medicine, 1996, Volume: 10, Issue:2

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Myocardial Infarction; Myocardial Ischemia; Radionuclide Imaging; Technetium Tc 99m Pyrophosphate

1996
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine

1996
Evaluation of gingival and periodontal conditions following causal periodontal treatment in patients treated with nifedipine and diltiazem.
    Journal of clinical periodontology, 1996, Volume: 23, Issue:7

    Topics: Analysis of Variance; Calcium Channel Blockers; Chi-Square Distribution; Dental Care for Chronically Ill; Dental Plaque Index; Diltiazem; Female; Follow-Up Studies; Gingival Overgrowth; Humans; Male; Myocardial Ischemia; Nifedipine; Outcome Assessment, Health Care; Periodontal Diseases; Periodontal Index; Statistics, Nonparametric

1996
Glyburide-reversible cardioprotective effects of BMS-180448: functional and energetic considerations.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:1

    Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium Channel Blockers; Cardiotonic Agents; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Guanidines; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Phosphocreatine; Potassium Channels; Rats; Rats, Sprague-Dawley

1997
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diltiazem; Enzyme-Linked Immunosorbent Assay; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardial Stunning; Prostaglandins; Swine; Thromboxane B2

1997
Silent myocardial ischemia: some good news.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adrenergic beta-Antagonists; Atenolol; Calcium Channel Blockers; Combined Modality Therapy; Coronary Disease; Death, Sudden, Cardiac; Diltiazem; Electrocardiography; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Nifedipine; Pilot Projects; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Vasodilator Agents

1997
Effects of lidocaine and diltiazem on recovery of electrophysiologic activity during partial reperfusion following severe myocardial ischemia in canine hearts.
    Journal of electrocardiology, 1997, Volume: 30, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Coronary Vessels; Diltiazem; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Infusions, Intravenous; Lidocaine; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Tachycardia, Ventricular; Treatment Outcome; Vasodilator Agents

1997
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:3

    Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines

1997
[The effect of prophylactic intravenous diltiazem drip infusion on myocardial ischemia during noncardiac surgery].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:6

    Topics: Aged; Aged, 80 and over; Anesthesia, General; Calcium Channel Blockers; Coronary Disease; Diltiazem; Elective Surgical Procedures; Female; Humans; Hypertension; Infusions, Intravenous; Intraoperative Care; Intraoperative Complications; Male; Middle Aged; Myocardial Ischemia; Premedication; Risk Factors

1997
[A clinico-pharmacological study of the antianginal and anti-ischemic efficacy of a new drug form of diltiazem with delayed release].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:3

    Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Physical Exertion; Time Factors

1997
Diltiazem inhibits the late increase in extracellular potassium by maintaining glycolytic ATP synthesis during myocardial ischemia.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Diltiazem; Extracellular Space; Glycolysis; Guinea Pigs; Heart Function Tests; Hydrogen-Ion Concentration; Male; Myocardial Ischemia; Potassium

1997
Effects of lidocaine and diltiazem on ventricular tachyarrhythmia and dispersion of conduction during severe myocardial ischemia in canine hearts.
    Journal of UOEH, 1997, Dec-01, Volume: 19, Issue:4

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Heart Conduction System; Lidocaine; Myocardial Ischemia; Sodium Channel Blockers; Tachycardia, Ventricular

1997
The protective effects of CP-060S on ischaemia- and reperfusion- induced arrhythmias in anaesthetized rats.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiazoles; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion; Piperidines; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines

1998
Cardioprotective effects of beraprost sodium against experimental ischemia and reperfusion as compared with propranolol and diltiazem.
    Research communications in molecular pathology and pharmacology, 1998, Volume: 99, Issue:3

    Topics: Animals; Diltiazem; Epoprostenol; Guinea Pigs; Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Propranolol; Vasodilator Agents

1998
Intravenous diltiazem and acute renal failure after cardiac operations.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:5

    Topics: Acute Kidney Injury; Age Factors; Arrhythmias, Cardiac; Calcium Channel Blockers; Cerebrovascular Disorders; Chi-Square Distribution; Coronary Artery Bypass; Coronary Disease; Creatinine; Diltiazem; Female; Humans; Incidence; Infusions, Intravenous; Intraoperative Care; Logistic Models; Male; Middle Aged; Myocardial Ischemia; Odds Ratio; Prevalence; Renal Dialysis; Retrospective Studies; Risk Factors; Stroke Volume; Vasodilator Agents

1998
Mechanism for the cardioprotective effects of the calcium channel blocker clentiazem during ischemia and reperfusion.
    Japanese circulation journal, 1998, Volume: 62, Issue:8

    Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Ferrets; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury

1998
Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.
    Pharmacological research, 1998, Volume: 38, Issue:3

    Topics: Animals; Diltiazem; Endothelin-1; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Swine

1998
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride.
    Basic research in cardiology, 1998, Volume: 93, Issue:4

    Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea

1998
[The effect of diltiazem on neurohumoral regulatory mechanisms in stenocardia patients].
    Likars'ka sprava, 1998, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Atrial Natriuretic Factor; Calcium Channel Blockers; Diltiazem; Exercise Tolerance; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Neurotransmitter Agents; Renin-Angiotensin System

1998
Noninvasive assessment of pharmaceutical intervention during myocardial ischemia-reperfusion in a canine model using two-dimensional 31P chemical shift imaging.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1998, Volume: 76, Issue:2-3

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Drug Evaluation; Energy Metabolism; Female; Gadolinium DTPA; Heart; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardium; Phosphocreatine; Phosphorus Isotopes; Propranolol

1998
Effects of diltiazem on myocardial perfusion abnormalities during exercise in patients with hypertrophic cardiomyopathy.
    Annals of nuclear medicine, 1998, Volume: 12, Issue:6

    Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Hypertrophic; Data Interpretation, Statistical; Diltiazem; Female; Heart; Heart Rate; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Myocardial Ischemia; Perfusion; Physical Exertion; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon

1998
Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Acidosis; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Extracellular Space; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Nifedipine; Phosphocreatine; Potassium; Time Factors; Verapamil

1999
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
    European journal of pharmacology, 1999, Jun-04, Volume: 373, Issue:2-3

    Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Heart Ventricles; Hypertension; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Rats; Rats, Wistar; Survival Analysis

1999
Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:4

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzyl Alcohol; Benzyl Alcohols; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Hemodynamics; In Vitro Techniques; Ion Transport; Lidocaine; Lymphocytes; Male; Myocardial Infarction; Myocardial Ischemia; Propionates; Propranolol; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; Time Factors; Ventricular Fibrillation

1999
Treatment with l-cis diltiazem before reperfusion reduces infarct size in the ischemic rabbit heart in vivo.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:4

    Topics: Anesthesia; Animals; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Heart; Hemodynamics; Isomerism; Male; Myocardial Infarction; Myocardial Ischemia; Rabbits; Reperfusion Injury; Time Factors

1999
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates

1999
An uncommon case of variant angina.
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:10

    Topics: Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Angiography; Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Ergonovine; Female; Hemodynamics; Humans; Infusions, Intravenous; Middle Aged; Myocardial Ischemia; Nitrates; Prognosis; Shock, Cardiogenic; Tissue Plasminogen Activator; Vasodilator Agents

1999
The Canadian Study of Cardiac Transplantation. Atherosclerosis. Investigators of the CASCADE Study.
    The Canadian journal of cardiology, 1999, Volume: 15, Issue:12

    Topics: Adult; Antihypertensive Agents; Arteriosclerosis; Aspirin; Cardiovascular Agents; Cyclosporine; Cytomegalovirus Infections; Diltiazem; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Middle Aged; Myocardial Ischemia; Postoperative Care; Postoperative Complications

1999
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiography; Endothelin-1; Enzyme Inhibitors; Heart Ventricles; Macrophages; Male; Microscopy; Myocardial Ischemia; Necrosis; Neutrophils; Nicorandil; Nifedipine; Papillary Muscles; Rabbits; Random Allocation; Vasodilator Agents

2000
[Two cases of microvascular vasospastic angina usefulness of 99mTc-tetrofosmin myocardial SPECT in clinical diagnosis].
    Kaku igaku. The Japanese journal of nuclear medicine, 2000, Volume: 37, Issue:1

    Topics: Calcium Channel Blockers; Diltiazem; Female; Heart; Humans; Male; Microvascular Angina; Middle Aged; Myocardial Ischemia; Nicorandil; Organophosphorus Compounds; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vasodilator Agents

2000
Protective effect of diltiazem against ischemia-induced decreases in regional myocardial flow in rat heart.
    European journal of pharmacology, 2000, Jun-09, Volume: 398, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Coronary Circulation; Diltiazem; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections; Male; Microspheres; Myocardial Ischemia; Nifedipine; Rats; Rats, Wistar; Regional Blood Flow; Time Factors

2000
Energy preserving effect of l-cis diltiazem in isolated ischemic and reperfused guinea pig hearts: a 31P-NMR study.
    Japanese journal of pharmacology, 2000, Volume: 83, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Nifedipine; Phosphocreatine; Phosphorus Isotopes

2000
The cardioprotective effects of a new 1,4-benzothiazepine derivative, JTV519, on ischemia/reperfusion-induced Ca2+ overload in isolated rat hearts.
    Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:5

    Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fluorometry; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazepines

2000
Diltiazem ameliorates contractile dysfunction without shortening of action potential duration in ischemic heart of anesthetized dogs.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:2

    Topics: Action Potentials; Anesthesia; Animals; Cardiovascular Agents; Diltiazem; Dogs; Female; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion

2001
Effects of CP-060S, a novel cardioprotective drug, in the methacholine-induced ECG change model in rats.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Choline; Coronary Vessels; Diltiazem; Electrocardiography; Heart Rate; Infusions, Parenteral; Injections, Intravenous; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasodilator Agents

2001
Ischemic preconditioning attenuates cardiac sympathetic nerve injury via ATP-sensitive potassium channels during myocardial ischemia.
    Circulation, 2001, Aug-28, Volume: 104, Issue:9

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Desipramine; Dialysis Solutions; Diltiazem; Dogs; Glyburide; Heart; Hemodynamics; Ischemic Preconditioning; Myocardial Ischemia; Nicorandil; Norepinephrine; Potassium Channels; Sympathetic Nervous System; Time Factors

2001
The gingival inflammatory infiltrate in cardiac patients treated with calcium antagonists.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:10

    Topics: Analysis of Variance; Calcium Channel Blockers; Case-Control Studies; Chi-Square Distribution; Diltiazem; Female; Gingival Hyperplasia; Gingivitis; Histiocytes; Humans; Immunoenzyme Techniques; Lymphocytes; Male; Myocardial Ischemia; Neutrophil Infiltration; Neutrophils; Nifedipine; Plasma Cells; Statistics, Nonparametric

2001
Differences in protective profiles of diltiazem isomers in ischemic and reperfused guinea pig hearts.
    European journal of pharmacology, 2002, Jan-11, Volume: 434, Issue:3

    Topics: Animals; Atrial Function, Left; Cardiovascular Agents; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; Isomerism; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Up-Regulation

2002
Diltiazem during reperfusion preserves high energy phosphates by protection of mitochondrial integrity.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2002, Volume: 21, Issue:2

    Topics: Adenine Nucleotides; Analysis of Variance; Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Diltiazem; Disease Models, Animal; Female; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Phosphocreatine; Probability; Rabbits; Random Allocation; Reference Values; Reperfusion Injury; Sensitivity and Specificity

2002
The long-lasting anti-anginal effects of CP-060S in a rat model of arginine vasopressin-induced myocardial ischaemia.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:3

    Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasoconstrictor Agents

2002
Selective L-type, T-type, and nonspecific calcium-channel blockers for stable angina pectoris.
    American heart journal, 2002, Volume: 144, Issue:1

    Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Humans; Mibefradil; Myocardial Ischemia

2002
Effects of diltiazem and noradrenaline on extracellular potassium changes in the globally ischaemic rat heart.
    Cardiovascular research, 1992, Volume: 26, Issue:11

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Diltiazem; Electrophysiology; Myocardial Ischemia; Norepinephrine; Potassium; Rats; Rats, Wistar; Ventricular Function

1992
Moderation of myocardial ischemia reperfusion injury by calcium channel and calmodulin receptor inhibition.
    Heart and vessels, 1992, Volume: 7, Issue:4

    Topics: Animals; Calcium Channels; Calmodulin-Binding Proteins; Coronary Circulation; Creatine Kinase; Diltiazem; Female; Male; Malondialdehyde; Models, Cardiovascular; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Oxygen Consumption; Reperfusion Injury; Swine; Trifluoperazine

1992
Effects of denopamine with or without diltiazem on the ischemic heart of anesthetized dogs.
    Japanese heart journal, 1992, Volume: 33, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Aorta; Diltiazem; Dogs; Ethanolamines; Female; Heart; Hemodynamics; Infusions, Intravenous; Male; Myocardial Ischemia; Regional Blood Flow; Stroke Volume

1992
Canine end-systolic pressure-length relationships: depressed by diltiazem, invalidated by ischemia.
    Journal of cardiothoracic and vascular anesthesia, 1992, Volume: 6, Issue:5

    Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Diltiazem; Dogs; Heart Rate; Myocardial Contraction; Myocardial Ischemia; Stroke Volume; Systole; Vascular Resistance; Ventricular Function, Left; Ventricular Outflow Obstruction

1992
[Silent myocardial ischemia with raised ST tract in 2 octogenarian patients without ischemic cardiopathy].
    La Clinica terapeutica, 1992, Volume: 141, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Angina Pectoris; Diltiazem; Electrocardiography; Electrocardiography, Ambulatory; Humans; Male; Myocardial Ischemia

1992
Ro 40-5967, a novel calcium channel antagonist, protects against ventricular fibrillation.
    European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3

    Topics: Animals; Benzimidazoles; Binding Sites; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Disease Susceptibility; Dogs; Dose-Response Relationship, Drug; Heart Rate; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Ventricular Fibrillation; Verapamil

1992