Page last updated: 2024-08-23

diltiazem and Cardiac Hypertrophy

diltiazem has been researched along with Cardiac Hypertrophy in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's9 (33.33)18.2507
2000's2 (7.41)29.6817
2010's0 (0.00)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Fakhar, M; Rashid, S; Zahid, S1
Abe, K; Haruna, M; Hirono, S; Ibii, N; Itoh, T; Tokumura, M1
Hirsch, AT; Inouye, IK; Massie, BM; Tubau, JF1
Abe, H; Fukushima, M; Hamanaka, Y; Inoue, M; Maeda, T; Matsumoto, M; Matsuyama, T; Nakajima, S; Shimazu, T; Yasui, K1
Ewy, GA1
Hope, RR; Lazzara, R1
Bhattacharya, SK; Johnson, PL1
Dzwonczyk, S; Grover, GJ; Monticello, TM1
Geshi, E; Katagiri, T; Konno, N; Watanabe, T; Yanagishita, T1
Aydin, S; Harper, JC; Noordzij, LA; Ruwhof, C; van der Laarse, A; van Wamel, JT1
Abe, M; Fujiwara, Y; Hamada, M; Hiwada, K; Matsuoka, H; Ohtani, T; Sekiya, M; Sumimoto, T; Suzuki, M1
Braunwald, E; Hamm, P; Lamas, GA; Pfeffer, MA; Rouleau, JL; Wertheimer, J1
Kimura, M; Koshiyama, H; Nogita, T; Senda, Y; Shida, Y; Shimaji, Y; Tanaka, T; Tohkai, H; Tutumi, S1
Bühler, FR1
Haneda, T; Obata, H; Tanaka, H1
Haywood, LJ1
Weiss, RJ1
Reeves, WC; Schildt, N; Whitesell, L; Wood, MA1
Besse, P; Colle, JP; Ohayon, J1
Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H1
Bent, B; Weiss, RJ1
Henderson, S; Massie, BM; Parmley, WW; Sievers, R; Szlachcic, J; Tubau, JF; Wikman-Coffelt, J1
Besse, PJ; Bonoron-Adèle, SM; Grellet, JP; Tariosse, LJ1
Boden, WE; Capone, RJ; Gibson, RS; Kleiger, RE; Schechtman, KB; Schwartz, DJ1
Abe, T; Harada, H; Inoue, N; Kazui, T; Komatsu, S; Okamoto, F; Sasaki, A; Sugimoto, S; Takagi, N; Yokoyama, H1
Agaccio, G; De Paulis, R; Di Summa, M; Donegani, E; Matani, A; Pignatelli, MG; Poletti, GA1
Brinkman, CJ; Huysmans, HA; Kappetein, AP; Los, GJ; van der Laarse, A; Weening, JJ1

Reviews

2 review(s) available for diltiazem and Cardiac Hypertrophy

ArticleYear
Calcium channel blockers as antihypertensive agents.
    The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A

    Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Humans; Hypertension; Ion Channels; Nifedipine; Time Factors; Vascular Resistance; Vasodilation; Verapamil

1984
The clinical uses of calcium antagonists.
    Advances in internal medicine, 1982, Volume: 27

    Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiomegaly; Diltiazem; Dogs; Humans; Myocardial Contraction; Nifedipine; Tachycardia; Verapamil

1982

Trials

6 trial(s) available for diltiazem and Cardiac Hypertrophy

ArticleYear
Calcium channel blockers as antihypertensive agents.
    The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A

    Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Humans; Hypertension; Ion Channels; Nifedipine; Time Factors; Vascular Resistance; Vasodilation; Verapamil

1984
Calcium channel blocking agents.
    Medical times, 1981, Volume: 109, Issue:8

    Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Diltiazem; Hemodynamics; Humans; Hypertension; Ion Channels; Nifedipine; Pyridines; Systole; Verapamil

1981
Do the results of randomized clinical trials of cardiovascular drugs influence medical practice? The SAVE Investigators.
    The New England journal of medicine, 1992, Jul-23, Volume: 327, Issue:4

    Topics: Adult; Aged; Aspirin; Calcium Channel Blockers; Captopril; Cardiomegaly; Cardiovascular Agents; Diltiazem; Drug Utilization; Female; Humans; Male; Middle Aged; Myocardial Infarction; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Survival Rate; Time Factors; United States

1992
Diltiazem and left ventricular mass regression.
    The American journal of cardiology, 1989, Oct-01, Volume: 64, Issue:12

    Topics: Cardiomegaly; Diltiazem; Humans; Hypertension; Randomized Controlled Trials as Topic

1989
Diltiazem-induced left ventricular mass regression in hypertensive patients.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:2

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Delayed-Action Preparations; Diltiazem; Humans; Hypertension; Middle Aged; Propranolol

1987
Clinical significance and prognostic importance of left ventricular hypertrophy in non-Q-wave acute myocardial infarction.
    The American journal of cardiology, 1988, Nov-15, Volume: 62, Issue:16

    Topics: Age Factors; Cardiomegaly; Clinical Trials as Topic; Creatine Kinase; Diltiazem; Electrocardiography; Humans; Isoenzymes; Myocardial Infarction; Prognosis; Random Allocation; Regression Analysis; Retrospective Studies; Risk Factors

1988

Other Studies

20 other study(ies) available for diltiazem and Cardiac Hypertrophy

ArticleYear
Structural basis of Klotho binding to VEGFR2 and TRPC1 and repurposing calcium channel blockers as TRPC1 antagonists for the treatment of age-related cardiac hypertrophy.
    Archives of biochemistry and biophysics, 2022, 04-15, Volume: 719

    Topics: Aged; Calcium; Calcium Channel Blockers; Calcium Signaling; Cardiomegaly; Diltiazem; Humans; TRPC Cation Channels; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2022
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2004, Volume: 26, Issue:6

    Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertension; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Stroke; Vasodilator Agents; Ventricular Pressure

2004
[Effect of diltiazem on diastolic performance of the hypertrophied left ventricle in patients with systemic hypertension and hypertrophic cardiomyopathy].
    Journal of cardiography, 1983, Volume: 13, Issue:4

    Topics: Administration, Oral; Adult; Benzazepines; Cardiomegaly; Cardiomyopathy, Hypertrophic; Diastole; Diltiazem; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction

1983
Regulation of membrane-mediated chronic muscle degeneration in dystrophic hamsters by calcium-channel blockers: diltiazem, nifedipine and verapamil.
    Journal of the neurological sciences, 1993, Volume: 115, Issue:1

    Topics: Animals; Body Weight; Calcium; Calcium Channel Blockers; Cardiomegaly; Creatine Kinase; Cricetinae; Diltiazem; Fructose-Bisphosphate Aldolase; Hypertrophy; L-Lactate Dehydrogenase; Magnesium; Male; Membranes; Muscles; Muscular Dystrophy, Animal; Nifedipine; Organ Size; Verapamil

1993
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left

1996
Reversal of early metabolic dysfunction in hypertensive rat left-ventricular myocytes by angiotensin-converting enzyme inhibition.
    Japanese heart journal, 1997, Volume: 38, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Cardiomegaly; Diltiazem; Hypertension; Imidazoles; Imidazolidines; Male; Mitochondria, Heart; Myocardium; Organelles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase

1997
Mechanical stress stimulates phospholipase C activity and intracellular calcium ion levels in neonatal rat cardiomyocytes.
    Cell calcium, 2001, Volume: 29, Issue:2

    Topics: Anesthetics, Local; Animals; Animals, Newborn; Anti-Inflammatory Agents; Calcium; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Culture Media, Serum-Free; Diltiazem; Fluorescent Dyes; Gadolinium; Hydrogen-Ion Concentration; Indicators and Reagents; Myocardium; Phospholipase D; Procaine; Rats; Rats, Wistar; Ruthenium Red; Stress, Mechanical; Type C Phospholipases

2001
Effect of disopyramide on left ventricular diastolic function in patients with hypertrophic cardiomyopathy: comparison with diltiazem.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:4

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Cardiomyopathies; Diltiazem; Disopyramide; Echocardiography, Doppler; Female; Heart Rate; Humans; Male; Middle Aged; Ventricular Function, Left

1992
ECG-gated cardiac scan and echocardiographic assessments of left ventricular hypertrophy: reversal by 6-month treatment with diltiazem.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Aged; Blood Pressure; Cardiomegaly; Diltiazem; Echocardiography; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Tomography, X-Ray Computed

1990
End-organ protection and antihypertensive therapy. Introduction.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 6

    Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Cardiomegaly; Diltiazem; Humans

1990
Response of isolated perfused heart to ischemia after long-term treatment of spontaneously hypertensive rats with diltiazem.
    Japanese circulation journal, 1990, Volume: 54, Issue:1

    Topics: Adenine Nucleotides; Animals; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Disease; Diltiazem; Energy Metabolism; Heart; Hypertension; In Vitro Techniques; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1990
Exercise, hypertension, and left ventricular mass.
    JAMA, 1990, Nov-14, Volume: 264, Issue:18

    Topics: Cardiomegaly; Diltiazem; Exercise; Humans; Hypertension; Propranolol

1990
Effect of diltiazem and ibuprofen on right ventricular hypertrophy in an experimental model of hypoxic pulmonary hypertension.
    The American journal of cardiology, 1985, Sep-01, Volume: 56, Issue:7

    Topics: Animals; Benzazepines; Cardiomegaly; Diltiazem; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Imidazoles; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains

1985
[Effects of injectable calcium blockers on cardiac function and relaxation in left ventricular hypertrophy].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78, Issue:12

    Topics: Adult; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomegaly; Coronary Vessels; Diltiazem; Hemodynamics; Humans; Injections, Intra-Arterial; Injections, Intravenous; Middle Aged; Myocardial Contraction; Verapamil

1985
[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:3

    Topics: Aldosterone; Animals; Aorta; Aortic Diseases; Benzazepines; Cardiomegaly; Diltiazem; Hindlimb; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin

1985
Diltiazem prevents hypertrophy progression, preserves systolic function, and normalises myocardial oxygen utilisation in the spontaneously hypertensive rat.
    Cardiovascular research, 1987, Volume: 21, Issue:8

    Topics: Animals; Cardiomegaly; Coronary Circulation; Diltiazem; Heart; Hypertension; In Vitro Techniques; Methyldopa; Myocardium; Myosins; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole

1987
Diltiazem and left ventricular hypertrophy in renovascular hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 1

    Topics: Administration, Oral; Animals; Blood Pressure; Cardiac Output; Cardiomegaly; Coronary Circulation; Diltiazem; Drug Administration Schedule; Drug Evaluation, Preclinical; Hypertension, Renovascular; Isometric Contraction; Male; Microspheres; Myocardial Contraction; Rats; Rats, Inbred SHR; Time Factors; Vascular Resistance

1988
[A comparative study of diltiazem blood cardioplegia in 49 patients undergoing aortic valve replacement with left ventricular hypertrophy].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1988, Volume: 36, Issue:10

    Topics: Adult; Aortic Valve; Blood; Cardiomegaly; Cardioplegic Solutions; Diltiazem; Drug Evaluation; Female; Heart Arrest, Induced; Heart Valve Prosthesis; Humans; Male; Middle Aged

1988
Improved tolerance to ischemia in hypertrophied myocardium pre and post cardiopulmonary bypass use of a calcium-channel blocker (diltiazem).
    Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1987, Volume: 9, Issue:1

    Topics: Cardiomegaly; Cardiopulmonary Bypass; Coronary Disease; Diltiazem; Female; Humans; Male; Middle Aged

1987
Assessment of hemodynamic function and tolerance to ischemia in the absence or presence of calcium antagonists in hearts of isoproterenol-treated, exercise-trained, and sedentary rats.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1988, Volume: 2, Issue:6

    Topics: Animals; Cardiomegaly; Cardioplegic Solutions; Creatine Kinase; Diltiazem; Fibrosis; Heart Arrest, Induced; Hemodynamics; Isoproterenol; Myocardium; Organ Size; Physical Education and Training; Rats; Verapamil

1988