Page last updated: 2024-08-23

diltiazem and Anoxemia

diltiazem has been researched along with Anoxemia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's12 (36.36)18.2507
2000's4 (12.12)29.6817
2010's4 (12.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aaronson, PI; Becker, S; Kizub, IV; Prieto-Lloret, J; Shaifta, Y; Snetkov, VA; Soloviev, AI; Strielkov, IV; Ward, JP1
Deng, W; Farricielli, L1
Li, J; Li, M; Liu, X; Meng, G1
Amano, A; Kurihara, H; Matsushita, S; Okada, T; Sakai, T; Watanabe, M1
Jernigan, NL; Resta, TC; Walker, BR1
Curtis, TM; de Gooyer, TE; Gardiner, TA; Humphries, P; Simpson, DA; Stevenson, KA; Stitt, AW1
Chesler, E; Lundquist, LJ; Weir, EK; Young, TE1
Henry, PD; Wahl, AM1
Ashraf, M; Rahamathulla, PM1
Ashraf, M; Benedict, J; Rahamathulla, PM; Schwartz, A1
Payne, RS; Rigor, BM; Schurr, A1
Brooks, KJ; Kauppinen, RA1
du Souich, P; Hartemann, D; Saunier, C1
Nagao, T; Vanhoutte, PM1
Clarke, W; Cohen, AH; Fouty, B; Hanson, K; McMurty, IF; Morris, K; Rodman, DM1
Aaronson, PI; Hague, D; Robertson, TP; Ward, JP1
Crenesse, D; Cursio, R; Gugenheim, J; Heurteaux, C; Laurens, M; Schmid-Alliana, A; Tornieri, K1
Gu, LM; Xiao, Y; Yuan, F; Zhou, ZN1
Liang, D; Thurman, RG1
Hashimoto, H; Hirano, M; Konishi, K; Utsunomiya, H1
Briggs-Tung, C; Cartee, GD; Holloszy, JO1
Katsumata, Y; Mori, S; Murakami, K; Yamamoto, C; Yoshino, M1
Abiko, Y; Hara, A; Matsumura, H1
Ishida, Y; Paul, RJ1
Katusic, ZS; Vanhoutte, PM1
Reeves, WC; Schildt, N; Whitesell, L; Wood, MA1
Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS1
Fukao, N; Fukumoto, T; Takeo, S; Tanaka, T; Tanonaka, K; Tazuma, Y; Yoshikawa, C1
Cartheuser, CF1
Escoubet, B; Griffaton, G; Lechat, P; Samuel, JL1
Battistella, P; Breda, JL; Clozel, JP; Delorme, N; Polu, JM1
Packer, M1
Chappell, SP; Henderson, AH; Lewis, MJ1

Reviews

1 review(s) available for diltiazem and Anoxemia

ArticleYear
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Lung Diseases, Obstructive; Nifedipine; Rats; Vasoconstriction; Verapamil

1985

Trials

1 trial(s) available for diltiazem and Anoxemia

ArticleYear
Hemodynamic effects of intravenous diltiazem in hypoxic pulmonary hypertension.
    Chest, 1987, Volume: 91, Issue:2

    Topics: Blood Gas Analysis; Diltiazem; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstructive; Male; Middle Aged; Oxygen; Oxygen Consumption; Random Allocation

1987

Other Studies

31 other study(ies) available for diltiazem and Anoxemia

ArticleYear
Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization.
    Cardiovascular research, 2013, Aug-01, Volume: 99, Issue:3

    Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Gap Junctions; Glycyrrhetinic Acid; Hypoxia; Male; Phosphorylation; Protein Phosphatase 1; Pulmonary Artery; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction

2013
Hypoxic hepatitis and acute liver failure in a patient with newly onset atrial fibrillation and diltiazem infusion.
    BMJ case reports, 2013, Sep-16, Volume: 2013

    Topics: Acute Kidney Injury; Aged; Atrial Fibrillation; Diltiazem; Hepatitis; Humans; Hypotension; Hypoxia; Liver Diseases; Liver Failure, Acute; Male; Thrombocytopenia; Vasodilator Agents

2013
Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.
    Clinical and experimental pharmacology & physiology, 2015, Volume: 42, Issue:4

    Topics: Angiotensin II; Animals; Apoptosis; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytoprotection; Diltiazem; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Hypoxia; Male; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Vascular Diseases

2015
Inhibition of connexin43 dephosphorylation is involved in protective effects of diltiazem on cardiac function during hypoxic injury.
    Histology and histopathology, 2011, Volume: 26, Issue:3

    Topics: Animals; Blotting, Western; Cardiotonic Agents; Connexin 43; Connexins; Diltiazem; Fluorescent Antibody Technique; Heart; Hemodynamics; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; Perfusion; Phosphorylation; Rats; Rats, Wistar

2011
Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4

    Topics: Animals; Diltiazem; Endothelin-1; Hypoxia; Kinetics; Male; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spermine; Vasodilation

2004
Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:12

    Topics: Animals; Apyrase; Cyclic Nucleotide Phosphodiesterases, Type 6; Dark Adaptation; Diltiazem; Enzyme-Linked Immunosorbent Assay; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Light; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitroimidazoles; Oxygen Consumption; Phosphoric Diester Hydrolases; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Rhodopsin; RNA, Messenger; Transcriptional Activation; Vascular Endothelial Growth Factor A

2006
Comparative effects of nifedipine, verapamil, and diltiazem on experimental pulmonary hypertension.
    The American journal of cardiology, 1983, Jan-01, Volume: 51, Issue:1

    Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Prostaglandins F; Pulmonary Wedge Pressure; Pyridines; Vascular Resistance; Verapamil

1983
Diltiazem and nitrendipine suppress hypoxic contracture in quiescent ventricular myocardium.
    European heart journal, 1983, Volume: 4, Issue:11

    Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rabbits

1983
Cardiac injury in short duration anoxia and modification by diltiazem, a calcium channel blocking agent.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:5

    Topics: Animals; Benzazepines; Calcium; Cardiomyopathies; Diltiazem; Hypoxia; Male; Mitochondria, Heart; Myocardium; Rats; Rats, Inbred Strains

1984
Effects of diltiazem on anoxic injury in the isolated rat heart.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:4

    Topics: Aerobiosis; Animals; Benzazepines; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Heart; Hypoxia; Male; Mitochondria, Heart; Myocardium; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains

1983
Synergism between diltiazem and MK-801 but not APV in protecting hippocampal slices against hypoxic damage.
    Brain research, 1995, Jul-03, Volume: 684, Issue:2

    Topics: Animals; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Hypoxia; Kinetics; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley

1995
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels.
    Neurochemistry international, 1993, Volume: 23, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Effect of acute and chronic moderate hypoxia on diltiazem kinetics and metabolism in the dog.
    Pharmacology, 1993, Volume: 47, Issue:6

    Topics: Acute Disease; Animals; Chronic Disease; Diltiazem; Dogs; Hypoxia; Male

1993
Electrical and mechanical changes during anoxic contractions of the isolated canine basilar artery.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:3

    Topics: Animals; Basilar Artery; Calcium; Diltiazem; Dogs; Electrophysiology; Female; Hypoxia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Potassium; Vasoconstriction

1993
Inhibition of cyclic 3'-5'-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats.
    The Journal of clinical investigation, 1996, Jan-01, Volume: 97, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; Perfusion; Phosphodiesterase Inhibitors; Piperidines; Pulmonary Circulation; Purinones; Quinazolines; Rats; Rats, Sprague-Dawley; Vasodilation

1996
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
    The Journal of physiology, 2000, Jun-15, Volume: 525 Pt 3

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; Dinucleoside Phosphates; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Hypoxia; Imidazoles; In Vitro Techniques; Ion Channel Gating; Lanthanum; Male; Membrane Potentials; Nifedipine; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Vasoconstriction; Verapamil

2000
Diltiazem reduces apoptosis in rat hepatocytes subjected to warm hypoxia-reoxygenation.
    Pharmacology, 2002, Volume: 65, Issue:2

    Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Enzyme Activation; Hepatocytes; Hot Temperature; Hypoxia; Liver; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Oxygen; Rats; Rats, Wistar; Reperfusion Injury

2002
[Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia].
    Sheng li xue bao : [Acta physiologica Sinica], 1992, Volume: 44, Issue:3

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Hemodynamics; Hypoxia; Male; Nifedipine; Ventricular Function; Verapamil

1992
Protective effects of the calcium antagonists diltiazem and TA3090 against hepatic injury due to hypoxia.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Hypoxia; Ischemia; L-Lactate Dehydrogenase; Liver; Liver Diseases; Oxygen; Rats; Rats, Sprague-Dawley; Trypan Blue

1992
[The effects of calcium antagonists on ventilation-perfusion mismatching in the canine lung].
    Kokyu to junkan. Respiration & circulation, 1992, Volume: 40, Issue:1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Hypoxia; Models, Biological; Nifedipine; Oxygen; Partial Pressure; Pulmonary Artery; Pulmonary Gas Exchange; Vasoconstriction; Ventilation-Perfusion Ratio; Verapamil

1992
Diverse effects of calcium channel blockers on skeletal muscle glucose transport.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 2

    Topics: 3-O-Methylglucose; Animals; Biological Transport; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Glucose; Hypoxia; Male; Methylglucosides; Muscles; Nifedipine; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil

1992
Effect of Ca2(+)-entry blocker on the stimulation of aerobic metabolism in rats acclimatized to high altitude hypoxia.
    Biochemical pharmacology, 1991, May-15, Volume: 41, Issue:10

    Topics: Adaptation, Physiological; Aerobiosis; Altitude; Animals; Calcium; Diltiazem; Hypoxia; Ketone Bodies; Lactates; Male; Rats; Rats, Inbred Strains; Uric Acid

1991
Effect of diltiazem on the oxymyoglobin level of myocardial cells in the isolated, perfused rat heart during hypoxia.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3

    Topics: Animals; Diltiazem; Heart; Hypoxia; Male; Myocardium; Myoglobin; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Ventricular Function, Left

1990
Effects of hypoxia on high-energy phosphagen content, energy metabolism and isometric force in guinea-pig taenia caeci.
    The Journal of physiology, 1990, Volume: 424

    Topics: Adenine Nucleotides; Aerobiosis; Animals; Calcium; Carbachol; Diltiazem; Energy Metabolism; Guinea Pigs; Histamine; Hypoxia; Isometric Contraction; Lactates; Lactic Acid; Male; Muscle, Smooth; Oxygen Consumption; Phosphocreatine; Potassium

1990
Anoxic contractions in isolated canine cerebral arteries: contribution of endothelium-derived factors, metabolites of arachidonic acid, and calcium entry.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cerebral Arteries; Cyclooxygenase Inhibitors; Diltiazem; Dinoprost; Dogs; Endothelium; Female; Hypoxia; Male; Potassium; Prostaglandins F; Serotonin; Uridine Triphosphate; Vasoconstriction

1986
Effect of diltiazem and ibuprofen on right ventricular hypertrophy in an experimental model of hypoxic pulmonary hypertension.
    The American journal of cardiology, 1985, Sep-01, Volume: 56, Issue:7

    Topics: Animals; Benzazepines; Cardiomegaly; Diltiazem; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Imidazoles; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains

1985
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
    Pharmacology, 1986, Volume: 33, Issue:3

    Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dogs; Female; Hypoxia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Serotonin; Verapamil

1986
Diltiazem and verapamil reduce the loss of adenine nucleotide metabolites from hypoxic hearts.
    Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:5

    Topics: Adenine Nucleotides; Adenosine; Animals; Body Water; Calcium; Creatine Kinase; Diltiazem; Female; Heart; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Kinetics; Male; Myocardial Contraction; Myocardium; Perfusion; Rabbits; Reference Values; Verapamil

1988
Slow channel inhibitor effects on brain function: tolerance to severe hypoxia in the rat.
    British journal of pharmacology, 1988, Volume: 95, Issue:3

    Topics: Animals; Bencyclane; Bepridil; Brain; Calcium Channel Blockers; Cinnarizine; Diltiazem; Electroencephalography; Fendiline; Flunarizine; Gallopamil; Heart Rate; Hypoxia; Nimodipine; Prenylamine; Pyrrolidines; Rats; Rats, Inbred Strains; Respiration; Verapamil

1988
Calcium antagonists stimulate prostaglandin synthesis by cultured rat cardiac myocytes and prevent the effects of hypoxia.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Animals; Bepridil; Calcium Channel Blockers; Cells, Cultured; Cobalt; Diltiazem; Dinoprostone; Epoprostenol; Fibroblasts; Glycogen; Heart; Hypoxia; Myocardium; Prostaglandins E; Pyrrolidines; Rats; Rats, Inbred Strains; Verapamil

1986
Myocardial reoxygenation damage: can it be circumvented?
    Cardiovascular research, 1985, Volume: 19, Issue:5

    Topics: Animals; Calcium; Cats; Diltiazem; Heart; Hypoxia; In Vitro Techniques; Lidoflazine; Myocardial Contraction; Myocardium; Ouabain; Oxygen; Papillary Muscles; Perfusion; Rabbits; Stimulation, Chemical; Verapamil

1985