Page last updated: 2024-08-23

diltiazem and Anal Fissure

diltiazem has been researched along with Anal Fissure in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	29 (51.79)	29.6817
2010's	20 (35.71)	24.3611
2020's	7 (12.50)	2.80

Authors

Authors	Studies
Connolly, A; Hardy, MO; Hill, AG; Jin, JZ; Mauiliu-Wallis, M; Singh, PP; Unasa, H; Weston, M	1
Almela, P; Espi, A; Ferriols, FL; Granero, EG; Hernandez, V; Herreros, B; Mínguez, M; Montón Rodriguez, C; Mora, F; Sanchiz, V	1
Buckley, DA; Phillips, PF; Soriano, LF	1
Hagen, KB; Hougaard, HT; Krarup, PM; Nordholm-Carstensen, A; Perregaard, H; Wahlstrøm, KL	1
Alayed, M; Albanyan, S; Albassam, A; Alhayyan, R; Aljazaeri, A; Alshehri, A; Alsubaie, H; Altokhais, T; Alzahem, A; Barghouthi, R	1
Acar, N; Acar, T; Atahan, K; Dilek, ON; Genç, H; Güngör, F; Hacıyanlı, M; Kamer, E	1
Azab, R; Doughan, S; El Charif, MH; Kassas, S; Kredly, R; Sbaity, E	1
Ala, S; Alvandipour, M; Khalvati, M; Koulaeinejad, N; Yazdanicharati, J	1
Coutinho, I; Gonçalo, M; Moura, AL; Santiago, L	1
Baltzer, AB; Buhl, T; Forkel, S; Geier, J	1
Bratoeva, KZ; Corbo, F; Franchini, C; Franco, CD; Ivanova, NA; Kolev, IN; Mandracchia, D; Stoyanov, GS; Trapani, A; Trapani, G; Tripodo, G	1
Ala, S; Ghorbanian, A; Hadianamrei, R; Saeedi, M	1
Raghavan, L; Rai, V; Sandler, L; Shah, M; Sharma, C	1
Bulus, H; Coskun, A; Tas, A; Varol, N	1
Schaus, V	1
Azami, R; Mazahir, S; Murtaza, G; Pardhan, A	1
Amoli, HA; Gandomkar, H; Heidari, R; Zeinoddini, A	1
Berasategui, J; Bernal, JC; Canelles, E; de-Tursi, L; Landete, FJ; Puche, J	1
Bussen, D; Herold, A; Joos, A; Klotz, J; Vershenya, S	1
Ala, S; Alvandipour, M; Enayatifard, R; Qobadighadikolaei, R	1
Hashemi, P; Motie, MR	1
Kaman, L; Medhi, B; Pandhi, P; Prakash, A; Prakash, O; Rao, RS	1
Bernal Sprekelsen, JC; Landete Molina, FJ; Lorente Fernández, L; Morera Ocón, F	1
Arthur, JD; El-Sayed, TY; Makin, CA; Walsh, CJ	1
Rose, RF; Wilkinson, SM	1
Jawaid, M; Masood, Z; Salim, M	1
Hashmi, F; Siddiqui, FG	1
Herzig, DO; Lu, KC	1
Abd Elhady, HM; Aboryia, MH; Hablus, MA; Ismail, TA; Othman, IH; Selim, MF	1
Leinonen, PT; Oikarinen, A; Riekki, R	1
Boeker, EB; Kruijer, MJ; Verbeek, PC	1
Pronk, A; Samim, M; Stoker, L; Twigt, B	1
Aydinoglu, A; Balcioglu, ME; Boleken, ME; Cevik, M; Karadag, CA; Koruk, I; Ocal, S	1
Baig, MK; Sains, P; Sajid, MS; Whitehouse, PA	1
Acheson, AG; Griffin, N; Scholefield, JH	1
Briel, JW; Schouten, WR; Zimmerman, DD	1
Jonas, M; Scholefield, JH; Speake, W	1
Ahmad, M; Balaji, NS	1
Aitola, P; Hiltunen, KM	1
Bielecki, K; Kolodziejczak, M	1
Cunningham, C; Jones, OM; Lindsey, I; Mortensen, NJ	1
Siproudhis, L; Slim, K	1
Jonas, M; Scholefield, J	2
Baten, MA; Chowdhury, RA; Haq, Z; Khatun, M; Rahman, M	1
Acheson, AG; Scholefield, JH	1
Dawson, PM; Kapoor, K; Kunanadam, T; Nash, GF; Saeb-Parsy, K	1
Jain, BK; Kumar, P; Saifee, Y; Shrivastava, UK	1
Chopra, S; Dhawan, S	1
Elósegui, JL; Enríquez Navascués, JM; Goena, I; Irureta, I; Mujika, JA; Placer, C	1
Bhardwaj, R; Parker, MC	1
Baig, MK; Cheek, E; Rimple, J; Sajid, MS	1
Carapeti, EA; Kamm, MA; Phillips, RK	1
Birks, M; Farouk, R; Knight, JS	1
Abercrombie, JF; Jonas, M; Neal, KR; Scholefield, JH	1
Cullen, PT; Kocher, HM; Leather, AJ; Steward, M	1

Reviews

14 review(s) available for diltiazem and Anal Fissure

Article	Year
A systematic review and meta-analysis of the efficacy of topical sphincterotomy treatments for anal fissure. International journal of colorectal disease, 2022, Volume: 37, Issue:1 Topics: Administration, Topical; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Nitroglycerin; Sphincterotomy; Treatment Outcome; Vasodilator Agents	2022
Recent advances in the pharmacotherapy of chronic anal fissure: an update. Asian journal of surgery, 2008, Volume: 31, Issue:3 Topics: Administration, Topical; Adrenergic alpha-Antagonists; Anal Canal; Botulinum Toxins; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Diltiazem; Fissure in Ano; Headache; Humans; Indoramin; Injections, Intralesional; Lidocaine; Nifedipine; Nitroglycerin; Ointments	2008
Anal fissure. The Surgical clinics of North America, 2010, Volume: 90, Issue:1 Topics: Acute Disease; Anal Canal; Botulinum Toxins, Type A; Calcium Channel Blockers; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Neuromuscular Agents; Nifedipine; Nitroglycerin; Vasodilator Agents	2010
Systematic review of the use of topical diltiazem compared with glyceryltrinitrate for the nonoperative management of chronic anal fissure. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:1 Topics: Administration, Topical; Chronic Disease; Diltiazem; Fissure in Ano; Headache; Humans; Nitroglycerin; Randomized Controlled Trials as Topic; Recurrence; Vasodilator Agents	2013
[Treatment of anal fissure]. Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:5 Topics: Anal Canal; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Fissure in Ano; Humans; Nitroglycerin; Ointments; Proctoscopy; Time Factors; Vasodilator Agents	2003
Chronic anal fissure. The British journal of surgery, 2004, Volume: 91, Issue:3 Topics: Anal Canal; Botulinum Toxins, Type A; Calcium Channel Blockers; Diltiazem; Fecal Incontinence; Fissure in Ano; Humans; Nitric Oxide Donors; Nitroglycerin; Postoperative Complications; Retreatment; Treatment Failure	2004
[Anal fissure. Which first line treatment?]. Annales de chirurgie, 2004, Volume: 129, Issue:5 Topics: Botulinum Toxins, Type A; Dilatation; Diltiazem; Evidence-Based Medicine; Fecal Incontinence; Fissure in Ano; Humans; Neuromuscular Agents; Nifedipine; Nitroglycerin; Patient Selection; Recurrence; Risk Factors; Treatment Outcome; Vasodilator Agents; Wound Healing	2004
Anal fissure. Clinical evidence, 2004, Issue:11 Topics: Anal Canal; Botulinum Toxins, Type A; Diltiazem; Female; Fissure in Ano; Humans; Male; Nitroglycerin	2004
Chemical sphincterotomy--first line of treatment for chronic anal fissure. Mymensingh medical journal : MMJ, 2005, Volume: 14, Issue:1 Topics: Botulinum Toxins; Calcium Channel Blockers; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Isosorbide Dinitrate; Nifedipine; Nitroglycerin; Vasodilator Agents	2005
Anal fissure (chronic). Clinical evidence, 2004, Issue:12 Topics: Anal Canal; Botulinum Toxins, Type A; Diltiazem; Female; Fissure in Ano; Humans; Male; Nitroglycerin	2004
Pharmacological advancements in the treatment of chronic anal fissure. Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:14 Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Albuterol; Botulinum Toxins; Calcium Channel Blockers; Carbachol; Central Nervous System Agents; Cholinergic Agonists; Chronic Disease; Complementary Therapies; Diltiazem; Drug Administration Schedule; Fissure in Ano; Humans; Indoramin; Nitrates; Nitroglycerin; Randomized Controlled Trials as Topic	2005
Nonsurgical approaches for the treatment of anal fissures. The American journal of gastroenterology, 2007, Volume: 102, Issue:6 Topics: Anal Canal; Botulinum Toxins; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Muscle Relaxation; Nitroglycerin; Vasodilator Agents	2007
Modern perspectives in the treatment of chronic anal fissures. Annals of the Royal College of Surgeons of England, 2007, Volume: 89, Issue:5 Topics: Botulinum Toxins; Chronic Disease; Diltiazem; Fissure in Ano; Humans; Nitric Oxide Donors; Nitroglycerin	2007
The efficacy of diltiazem and glyceryltrinitrate for the medical management of chronic anal fissure: a meta-analysis. International journal of colorectal disease, 2008, Volume: 23, Issue:1 Topics: Chronic Disease; Diltiazem; Fissure in Ano; Headache; Humans; Nitroglycerin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Treatment Outcome	2008

Trials

22 trial(s) available for diltiazem and Anal Fissure

Article	Year
Botulinum Toxin Injection Plus Topical Diltiazem for Chronic Anal Fissure: A Randomized Double-Blind Clinical Trial and Long-term Outcome. Diseases of the colon and rectum, 2021, 12-01, Volume: 64, Issue:12 Topics: Administration, Topical; Adult; Anal Canal; Botulinum Toxins; Case-Control Studies; Chronic Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Fissure in Ano; Humans; Injections; Male; Manometry; Middle Aged; Neurotoxins; Placebos; Recurrence; Spain; Tertiary Care Centers; Treatment Outcome; Vasodilator Agents; Wound Healing	2021
Treatment of chronic anal fissure: a feasibility study on Levorag® Emulgel versus Diltiazem gel 2. International journal of colorectal disease, 2020, Volume: 35, Issue:4 Topics: Adult; beta-Glucans; Chronic Disease; Diltiazem; Drug Combinations; Feasibility Studies; Female; Fissure in Ano; Humans; Male; Pain; Plant Extracts; Wound Healing; Young Adult	2020
A prospective, double-blind, randomized, placebo-controlled trial comparing the efficacy of polyethylene glycol versus polyethylene glycol combined with topical diltiazem for treating anal fissure in children. Journal of pediatric surgery, 2020, Volume: 55, Issue:10 Topics: Adolescent; Child; Constipation; Diltiazem; Double-Blind Method; Fissure in Ano; Humans; Laxatives; Polyethylene Glycols; Prospective Studies; Vasodilator Agents	2020
Comparative efficacy of medical treatment versus surgical sphincterotomy in the treatment of chronic anal fissure. Nigerian journal of clinical practice, 2020, Volume: 23, Issue:4 Topics: Chronic Disease; Diltiazem; Fissure in Ano; Humans; Nitroglycerin; Pain Management; Quality of Life; Sphincterotomy; Treatment Outcome; Vasodilator Agents	2020
MEBO versus topical Diltiazem versus a combination of both ointments in the treatment of acute anal fissure: a randomized clinical trial protocol. BMC complementary medicine and therapies, 2021, Feb-24, Volume: 21, Issue:1 Topics: Adult; Calcium Channel Blockers; Clinical Protocols; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Sitosterols; Wound Healing; Young Adult	2021
Topical Minoxidil Versus Topical Diltiazem for Chemical Sphincterotomy of Chronic Anal Fissure: A Prospective, Randomized, Double-Blind, Clinical Trial. World journal of surgery, 2018, Volume: 42, Issue:7 Topics: Administration, Topical; Adolescent; Adult; Blood Pressure; Chronic Disease; Diltiazem; Double-Blind Method; Drug Hypersensitivity; Female; Fissure in Ano; Headache; Hemorrhage; Humans; Male; Middle Aged; Minoxidil; Pain; Prospective Studies; Pruritus; Wound Healing; Young Adult	2018
Topical diltiazem vs. topical glyceril trinitrate in the treatment of chronic anal fissure: a prospective, randomized, double-blind trial. Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:4 Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Diltiazem; Double-Blind Method; Female; Fissure in Ano; Gels; Headache; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Pain Measurement; Patient Preference; Treatment Outcome; Vasodilator Agents; Wound Healing	2012
Comparison of topical isosorbide mononitrate, topical diltiazem, and their combination in the treatment of chronic anal fissure. Asian journal of surgery, 2013, Volume: 36, Issue:4 Topics: Administration, Topical; Adult; Calcium Channel Blockers; Chronic Disease; Diltiazem; Drug Therapy, Combination; Female; Fissure in Ano; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Pain Measurement; Treatment Outcome	2013
Diltiazem vs. glyceryl tri-nitrate for symptomatic relief in anal fissure: a randomised clnical study. JPMA. The Journal of the Pakistan Medical Association, 2014, Volume: 64, Issue:5 Topics: Adult; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Vasodilator Agents	2014
Partial lateral internal sphincterotomy versus combined botulinum toxin A injection and topical diltiazem in the treatment of chronic anal fissure: a randomized clinical trial. Diseases of the colon and rectum, 2015, Volume: 58, Issue:2 Topics: Administration, Topical; Adult; Anal Canal; Botulinum Toxins, Type A; Chronic Disease; Digestive System Surgical Procedures; Diltiazem; Fecal Incontinence; Female; Fissure in Ano; Humans; Injections, Intramuscular; Male; Neuromuscular Agents; Treatment Outcome; Vasodilator Agents	2015
Comparison of captopril (0.5%) cream with diltiazem (2%) cream for chronic anal fissure: a prospective randomized double-blind two-centre clinical trial. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2016, Volume: 18, Issue:5 Topics: Administration, Topical; Adolescent; Adult; Aged; Anal Canal; Captopril; Chronic Disease; Defecation; Diltiazem; Double-Blind Method; Female; Fissure in Ano; Humans; Male; Middle Aged; Pain Measurement; Prospective Studies; Pruritus Ani; Treatment Outcome; Vasodilator Agents; Young Adult	2016
Chronic Anal Fissure: A Comparative Study of Medical Treatment Versus Surgical Sphincterotomy. Acta medica Iranica, 2016, Volume: 54, Issue:7 Topics: Administration, Topical; Adult; Aged; Anal Canal; Chronic Disease; Digestive System Surgical Procedures; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Pain Management; Retrospective Studies; Treatment Outcome; Vasodilator Agents; Young Adult	2016
Topical diltiazem hydrochloride and glyceryl trinitrate in the treatment of chronic anal fissure. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009, Volume: 19, Issue:10 Topics: Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Nitroglycerin; Vasodilator Agents	2009
Long-term prospective randomised clinical and manometric comparison between surgical and chemical sphincterotomy for treatment of chronic anal fissure. South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2009, Volume: 47, Issue:4 Topics: Adolescent; Adult; Aged; Anal Canal; Botulinum Toxins; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Manometry; Middle Aged; Nitroglycerin; Time Factors; Vasodilator Agents; Young Adult	2009
Topical diltiazem cream versus botulinum toxin a for the treatment of chronic anal fissure: a double-blind randomized clinical trial. Annals of surgery, 2012, Volume: 255, Issue:1 Topics: Administration, Topical; Adult; Botulinum Toxins, Type A; Chronic Disease; Diltiazem; Double-Blind Method; Female; Fissure in Ano; Follow-Up Studies; Humans; Injections, Intramuscular; Male; Middle Aged; Neuromuscular Agents; Pain Measurement; Prospective Studies; Vasodilator Agents; Wound Healing	2012
A prospective, randomized, double-blind study comparing the efficacy of diltiazem, glyceryl trinitrate, and lidocaine for the treatment of anal fissure in children. Pediatric surgery international, 2012, Volume: 28, Issue:4 Topics: Anesthetics, Local; Child; Child, Preschool; Diltiazem; Double-Blind Method; Female; Fissure in Ano; Humans; Infant; Lidocaine; Male; Nitroglycerin; Prospective Studies; Vasodilator Agents	2012
A prospective randomized trial of diltiazem and glyceryltrinitrate ointment in the treatment of chronic anal fissure. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5, Issue:3 Topics: Administration, Topical; Adult; Aged; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Prospective Studies; Time Factors; Vasodilator Agents; Wound Healing	2003
A comparison of the effects of diltiazem and glyceryl trinitrate ointment in the treatment of chronic anal fissure: a randomized clinical trial. Surgery today, 2007, Volume: 37, Issue:6 Topics: Administration, Topical; Adolescent; Adult; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Prospective Studies; Treatment Outcome; Vasodilator Agents	2007
[Initial response to topical diltiazem can predict outcome of chronic anal fissure]. Cirugia espanola, 2007, Volume: 82, Issue:1 Topics: Administration, Topical; Adult; Aged; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Prognosis	2007
Topical diltiazem and bethanechol decrease anal sphincter pressure and heal anal fissures without side effects. Diseases of the colon and rectum, 2000, Volume: 43, Issue:10 Topics: Administration, Topical; Adult; Aged; Anal Canal; Bethanechol; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Female; Fissure in Ano; Humans; Male; Manometry; Middle Aged; Pain; Parasympathomimetics; Pilot Projects; Pressure	2000
A randomized trial of oral vs. topical diltiazem for chronic anal fissures. Diseases of the colon and rectum, 2001, Volume: 44, Issue:8 Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Chronic Disease; Diltiazem; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fissure in Ano; Humans; Male; Manometry; Middle Aged; Pain Measurement; Wound Healing	2001
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure. The British journal of surgery, 2002, Volume: 89, Issue:4 Topics: Adult; Aged; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Female; Fissure in Ano; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Pain Measurement; Prospective Studies; Treatment Outcome; Vasodilator Agents	2002

Other Studies

20 other study(ies) available for diltiazem and Anal Fissure

Article	Year
Contact allergy to topical diltiazem with co-sensitization to glyceryl trinitrate. Contact dermatitis, 2022, Volume: 86, Issue:5 Topics: Administration, Topical; Dermatitis, Allergic Contact; Diltiazem; Fissure in Ano; Humans; Nitroglycerin	2022
Systemic allergic contact dermatitis associated with topical diltiazem and/or cinchocaine. Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:7 Topics: Anesthetics, Local; Calcium Channel Blockers; Dermatitis, Allergic Contact; Dibucaine; Diltiazem; Female; Fissure in Ano; Humans; Middle Aged; Patch Tests	2018
Contact dermatitis caused by diltiazem cream and cross-reactivity with other calcium channel blockers. Contact dermatitis, 2018, Volume: 79, Issue:4 Topics: Calcium Channel Blockers; Cross Reactions; Dermatitis, Allergic Contact; Diltiazem; Fissure in Ano; Humans; Male; Middle Aged; Nifedipine; Skin Cream; Verapamil	2018
In vitro and ex vivo studies on diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment. International journal of pharmaceutics, 2019, Feb-25, Volume: 557 Topics: Acrylic Resins; Administration, Rectal; Animals; Chronic Disease; Diltiazem; Drug Delivery Systems; Drug Liberation; Fissure in Ano; Gels; Methylcellulose; Mucous Membrane; Poloxamer; Swine	2019
Quality of compounded topical 2% diltiazem hydrochloride formulations for anal fissure. World journal of gastroenterology, 2013, Sep-14, Volume: 19, Issue:34 Topics: Administration, Topical; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Drug Compounding; Fissure in Ano; Humans; Pharmacy	2013
[Topical diltiazem preparations for the treatment of anal fissures]. Journal de pharmacie de Belgique, 2013, Issue:4 Topics: Administration, Topical; Calcium Channel Blockers; Chemistry, Pharmaceutical; Diltiazem; Fissure in Ano; Humans; Ointments; Patient Education as Topic; Pharmacists	2013
Long-term follow-up of chronic anal fissure (CAF) on diltiazem 2% using a telephone questionnaire. Do results change? Revista espanola de enfermedades digestivas, 2015, Volume: 107, Issue:4 Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Chronic Disease; Diltiazem; Drug Administration Schedule; Female; Fissure in Ano; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Surveys and Questionnaires; Telephone; Treatment Outcome; Young Adult	2015
Combined approach in the treatment of chronic anal fissures. Updates in surgery, 2015, Volume: 67, Issue:1 Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Digestive System Surgical Procedures; Diltiazem; Drug Therapy, Combination; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Treatment Outcome; Vasodilator Agents; Young Adult	2015
[2% diltiazem as initial treatment of chronic anal fissures]. Cirugia espanola, 2008, Volume: 84, Issue:3 Topics: Calcium Channel Blockers; Chronic Disease; Diltiazem; Drug Administration Schedule; Fissure in Ano; Humans	2008
A pilot comparative study of fissurectomy/diltiazem and fissurectomy/botulinum toxin in the treatment of chronic anal fissure. Techniques in coloproctology, 2008, Volume: 12, Issue:4 Topics: Adult; Botulinum Toxins, Type A; Calcium Channel Blockers; Chi-Square Distribution; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Neuromuscular Agents; Pilot Projects; Retrospective Studies; Statistics, Nonparametric; Treatment Outcome	2008
Contact sensitization to topical diltiazem. Contact dermatitis, 2009, Volume: 60, Issue:6 Topics: Administration, Topical; Adult; Calcium Channel Blockers; Dermatitis, Allergic Contact; Diltiazem; Fissure in Ano; Humans; Male; Ointments	2009
Diltiazem (2%) versus glyceryl trinitrate cream (0.2%) in the management of chronic anal fissure. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009, Volume: 19, Issue:12 Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Nitroglycerin; Vasodilator Agents; Wound Healing; Young Adult	2009
Contact allergy to diltiazem cream. Contact dermatitis, 2010, Volume: 63, Issue:4 Topics: Administration, Topical; Calcium Channel Blockers; Dermatitis, Allergic Contact; Diltiazem; Drug Eruptions; Female; Fissure in Ano; Humans; Middle Aged	2010
[Treatment of chronic anal fissures: diltiazem or isosorbide dinitrate as first choice?]. Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155 Topics: Cost-Benefit Analysis; Diltiazem; Fissure in Ano; Humans; Isosorbide Dinitrate; Ointments; Patient Compliance; Treatment Outcome	2011
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17). The British journal of surgery, 2002, Volume: 89, Issue:9 Topics: Chronic Disease; Diltiazem; Fissure in Ano; Humans; Nitroglycerin; Randomized Controlled Trials as Topic; Vasodilator Agents	2002
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17). The British journal of surgery, 2002, Volume: 89, Issue:9 Topics: Chronic Disease; Diltiazem; Fissure in Ano; Humans; Isosorbide Dinitrate; Nitric Oxide Donors; Nitroglycerin; Randomized Controlled Trials as Topic; Vasodilator Agents	2002
Diltiazem heals glyceryl trinitrate-resistant chronic anal fissures: a prospective study. Diseases of the colon and rectum, 2002, Volume: 45, Issue:8 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Fissure in Ano; Gels; Humans; Male; Middle Aged; Nitroglycerin; Ointments; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; Vasodilator Agents; Wound Healing	2002
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17). The British journal of surgery, 2002, Volume: 89, Issue:10 Topics: Chronic Disease; Diltiazem; Fissure in Ano; Humans; Nitroglycerin; Randomized Controlled Trials as Topic; Vasodilator Agents	2002
The long-term results of diltiazem treatment for anal fissure. International journal of clinical practice, 2006, Volume: 60, Issue:11 Topics: Adult; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Time Factors; Treatment Outcome; Vasodilator Agents	2006
Topical diltiazem ointment in the treatment of chronic anal fissure. The British journal of surgery, 2001, Volume: 88, Issue:4 Topics: Administration, Topical; Adolescent; Adult; Aged; Calcium Channel Blockers; Child; Chronic Disease; Diltiazem; Female; Fissure in Ano; Humans; Male; Middle Aged; Ointments; Prospective Studies; Treatment Outcome; Wound Healing	2001