diltiazem has been researched along with Acute Liver Injury, Drug-Induced in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akindele, AJ; Amagon, KI; Oludadepo, GO; Osiagwu, DD; Singh, D | 1 |
| Hunt, CA; Kim, SH; Park, S; Roberts, MS; Ropella, GE | 1 |
| Lewin, JJ; Nappi, JM; Taylor, MH | 1 |
| Esteban, A; Graells, ML; Mayol, MJ; Pérez-Mateo, M; Satorres, J | 1 |
| McBride, JW; Swenson, LJ; Traverse, JH | 1 |
| Hamrick, ME; Harris, SR | 1 |
| Farghali, H; Kmonícková, E; Lotková, H; Martínek, J | 1 |
| Byrd, RP; Fields, CL; Kanathur, N; Mathai, MG; Roy, TM | 1 |
| Deakin, CD; Fagan, EA; Gove, CD; Tredger, JM; Williams, R | 1 |
| Gohara, S; Inomata, R; Itoh, S; Matsuyama, Y; Yamagishi, F | 1 |
| Therkelsen, K; Toft, E; Vyberg, M | 1 |
| Colombo, E; Romanò, M; Spinelli, A | 1 |
| Gibbs, DD; Glynn, MJ; Padley, SP; Shallcross, H | 1 |
| Gohara, S; Itoh, S; Matsuo, S; Yamaba, Y | 1 |
| London, RL; Matulewicz, TJ; Sarachek, NS | 1 |
2 review(s) available for diltiazem and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Acute hepatic injury after treatment with diltiazem.
Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Diltiazem; Drug Therapy, Combination; Female; Humans; Renal Dialysis | 1994 |
19 other study(ies) available for diltiazem and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Protective effect of carvedilol alone and coadministered with diltiazem and prednisolone on doxorubicin and 5-fluorouracil-induced hepatotoxicity and nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Antibiotics, Antineoplastic; Carbazoles; Carvedilol; Chemical and Drug Induced Liver Injury; Diltiazem; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kidney; Lipid Peroxidation; Liver; Oxidative Stress; Prednisolone; Propanolamines; Protective Agents; Random Allocation; Rats; Rats, Wistar; Treatment Outcome | 2018 |
Tracing multiscale mechanisms of drug disposition in normal and diseased livers.
Topics: Animals; Chemical and Drug Induced Liver Injury; Diltiazem; Disease Models, Animal; In Vitro Techniques; Liver; Liver Diseases; Liver Diseases, Alcoholic; Male; Models, Biological; Monte Carlo Method; Pharmaceutical Preparations; Rats; Rats, Wistar; Tissue Distribution | 2010 |
Rhabdomyolysis with concurrent atorvastatin and diltiazem.
Topics: Acute Disease; Acute Kidney Injury; Atorvastatin; Cardiovascular Agents; Chemical and Drug Induced Liver Injury; Diltiazem; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Rhabdomyolysis | 2002 |
Protective effect of diltiazem against acetaminophen hepatotoxicity in mice.
Topics: Acetaminophen; Acetylcysteine; Animals; Calcium; Cell Survival; Chemical and Drug Induced Liver Injury; Diltiazem; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Liver; Mice | 1995 |
Antagonism of acetaminophen hepatotoxicity by phospholipase A2 inhibitors.
Topics: Acetaminophen; Animals; Calcium; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlorpromazine; Diltiazem; DNA; Homeostasis; Male; Mice; Mitochondria, Liver; NADP; Oxidation-Reduction; Phospholipases A; Phospholipases A2 | 1993 |
Evaluation of calcium channel blockers as potential hepatoprotective agents in oxidative stress injury of perfused hepatocytes.
Topics: Adenosine Triphosphatases; Animals; Calcium Channel Blockers; Chemical and Drug Induced Liver Injury; Diltiazem; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxides; Liver Diseases; Male; Oxidative Stress; Oxygen Consumption; Perfusion; Rats; Rats, Wistar; tert-Butylhydroperoxide; Verapamil | 2000 |
Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis.
Topics: Calcium Channel Blockers; Chemical and Drug Induced Liver Injury; Diltiazem; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Rhabdomyolysis; Simvastatin | 2001 |
Delayed calcium channel blockade with diltiazem reduces paracetamol hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Diltiazem; Drug Administration Schedule; Liver Diseases; Liver Regeneration; Male; Mice; Nifedipine | 1991 |
Calcium staining by the glyoxal-bis-(2-hydroxyanil)-method in the livers of rats treated with CCl4, diltiazem, and with both agents together.
Topics: Aminophenols; Animals; Calcium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diltiazem; Indicators and Reagents; Liver; Rats; Staining and Labeling | 1990 |
Diltiazem-induced granulomatous hepatitis.
Topics: Aged; Aspirin; Atenolol; Chemical and Drug Induced Liver Injury; Diltiazem; Female; Granuloma; Humans; Liver; Liver Function Tests; Myocardial Infarction | 1991 |
[Changes in liver enzymes during treatment with diltiazem. Description of 2 cases].
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Diltiazem; gamma-Glutamyltransferase; Humans; Liver Diseases; Male; Middle Aged | 1987 |
Fatal renal and hepatic toxicity after treatment with diltiazem.
Topics: Acute Kidney Injury; Aged; Chemical and Drug Induced Liver Injury; Coronary Disease; Diltiazem; Humans; Male | 1987 |
Effects of calcium antagonist diltiazem on liver calcium content and necrosis of hepatocytes in rats following treatment with CCL4.
Topics: Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diltiazem; Female; Liver; Necrosis; Rats; Rats, Inbred Strains | 1988 |
Diltiazem and granulomatous hepatitis.
Topics: Benzazepines; Chemical and Drug Induced Liver Injury; Diltiazem; Granuloma; Humans; Liver; Male; Middle Aged | 1985 |