Page last updated: 2024-10-26

dilazep and Reperfusion Injury

dilazep has been researched along with Reperfusion Injury in 5 studies

Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Dilazep has been reported to inhibit edema formation in cerebral ischemia model of spontaneously hypertensive rats."1.28Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. ( Abe, K; Igarashi, N; Ikuta, J; Kawagoe, J; Kogure, K; Shimizu, S; Yamauchi, Y, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itoh, T1
Abe, K2
Tokumura, M1
Hirono, S1
Haruna, M1
Ibii, N1
Hoque, AN1
Hoque, N1
Hara, A1
Hashizume, H1
Ichihara, K1
Abiko, Y1
Kawagoe, J1
Ikuta, J2
Igarashi, N1
Shimizu, S2
Yamauchi, Y2
Kogure, K1
Nakamura, M1
Hanaki, Y1
Sugiyama, S1
Ajioka, M1
Kondo, T1
Fukushima, A1
Ozawa, T1

Other Studies

5 other studies available for dilazep and Reperfusion Injury

ArticleYear
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2004, Volume: 26, Issue:6

    Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertensio

2004
Cardioprotective effect of K-7259, a novel dilazep derivative, against ischemia-reperfusion damage in isolated, working rat hearts.
    Japanese journal of pharmacology, 1997, Volume: 73, Issue:4

    Topics: Animals; Dilazep; Disease Models, Animal; Heart; Lipid Peroxidation; Male; Malondialdehyde; Myocardi

1997
Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Dilazep; Evans Blue; Male; Rats; Rats, Inbred S

1992
[Effect of dilazep dihydrochloride on ischemia and reperfusion-induced cerebral injury in spontaneously hypertensive rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 95, Issue:5

    Topics: Animals; Azepines; Body Water; Brain; Brain Ischemia; Dilazep; Infusions, Intravenous; Lipid Peroxid

1990
Acceleration of recovery of mitochondrial function after coronary reperfusion by various coronary dilating drugs in canine hearts.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Dilazep; Diltiazem; Dogs; Female; Heart Rate; Hemodyn

1989