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dilazep and Glomerulonephritis, IGA

dilazep has been researched along with Glomerulonephritis, IGA in 9 studies

Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.

Glomerulonephritis, IGA: A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We collected data for 44 IgA nephropathy children treated with multi-drug combination therapy."1.48Serum IgA/C3 and glomerular C3 staining predict severity of IgA nephropathy. ( Hosoya, M; Kawasaki, Y; Maeda, R; Ohara, S; Suyama, K, 2018)
"Some patients with severe immunoglobulin A nephropathy (IgAN) are resistant to multi-drug combination therapy; however, there have been few reports on the risk factors for non-responsiveness to treatment for severe IgAN."1.40Resistance factors for the treatment of immunoglobulin A nephropathy with diffuse mesangial proliferation. ( Hashimoto, K; Hosoya, M; Kanno, S; Kawasaki, Y; Miyazaki, K; Ono, A; Sato, M; Suyama, K; Suzuki, Y, 2014)
"Immunofluorescence study revealed IgA nephropathy."1.35Behçet's disease complicated by IgA nephropathy with nephrotic syndrome. ( Hashimoto, T; Inayama, Y; Iwatsubo, K; Kihara, M; Kokuho, T; Kuji, T; Oshikawa, J; Tamura, K; Tanaka, K; Toya, Y; Umemura, S; Yabana, M; Yanagi, M; Yoshida, S, 2008)
" Group I (early-treatment group, n = 10) was orally treated with 300 mg/kg body weight of this drug from 12 weeks of age until 60 weeks of age, and group II (late-treatment group, n = 10) was also treated with the same dosage of this drug from 20 weeks of age until 60 weeks of age."1.31Effect of dilazep hydrochlorideon the Im munohistopathology of IgA nephropathy in ddY mice. ( Hayashi, T; Kaneko, S; Shirato, I; Shou, I; Thang, NT; Tomino, Y, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawasaki, Y2
Maeda, R1
Ohara, S1
Suyama, K2
Hosoya, M2
Miyazaki, K1
Kanno, S1
Ono, A1
Suzuki, Y1
Sato, M1
Hashimoto, K1
Moriyama, T1
Iwasaki, C1
Tanaka, K2
Ochi, A1
Shimizu, A1
Shiohira, S1
Itabashi, M1
Takei, T1
Uchida, K1
Tsuchiya, K1
Nitta, K1
Taji, Y1
Kuwahara, T2
Shikata, S1
Morimoto, T1
Hashimoto, T1
Toya, Y1
Kihara, M1
Yabana, M1
Inayama, Y1
Iwatsubo, K1
Yanagi, M1
Oshikawa, J1
Kokuho, T1
Kuji, T1
Yoshida, S1
Tamura, K1
Umemura, S1
Yoshida, H1
Kanatsu, K1
Muso, E1
Sekita, K1
Ono, T1
Konishi, N1
Kanda, C1
Minakata, T1
Morimoto, K1
Ebihara, I1
Nakamura, T1
Suzuki, S1
Ushiyama, C1
Shimada, N1
Suzaki, M1
Koide, H1
Hayashi, T1
Kaneko, S1
Thang, NT1
Shou, I1
Shirato, I1
Tomino, Y1
Haramaki, R1
Tamaki, K1
Fujisawa, M1
Ikedo, H1
Haramaki, N1
Okuda, S1

Reviews

1 review available for dilazep and Glomerulonephritis, IGA

ArticleYear
Meta-analysis of antiplatelet therapy for IgA nephropathy.
    Clinical and experimental nephrology, 2006, Volume: 10, Issue:4

    Topics: Dilazep; Dipyridamole; Glomerulonephritis, IGA; Humans; Kidney Function Tests; Platelet Aggregation

2006

Trials

1 trial available for dilazep and Glomerulonephritis, IGA

ArticleYear
Steroid therapy and urinary transforming growth factor-beta1 in IgA nephropathy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Dilazep; Female; Glomerulonephritis; Glomerulonephritis, IGA; Humans; Immunohisto

2001

Other Studies

7 other studies available for dilazep and Glomerulonephritis, IGA

ArticleYear
Serum IgA/C3 and glomerular C3 staining predict severity of IgA nephropathy.
    Pediatrics international : official journal of the Japan Pediatric Society, 2018, Volume: 60, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Biopsy; Child; Complement C3; D

2018
Resistance factors for the treatment of immunoglobulin A nephropathy with diffuse mesangial proliferation.
    Nephrology (Carlton, Vic.), 2014, Volume: 19, Issue:7

    Topics: Age of Onset; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biopsy; Calgranulin A; Calgra

2014
Effects of combination therapy with renin-angiotensin system inhibitors and eicosapentaenoic acid on IgA nephropathy.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cohort Studies; Dilazep; Drug Therapy, Combination; Eicosap

2013
Behçet's disease complicated by IgA nephropathy with nephrotic syndrome.
    Clinical and experimental nephrology, 2008, Volume: 12, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Behcet Syndrome; Benzimidazoles; Biphen

2008
Effects of an anti-platelet drug (dilazep) in IgA nephropathy: comparison of clinical effects with renal biopsy findings.
    Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:4

    Topics: Adult; Biopsy; Dilazep; Female; Glomerulonephritis, IGA; Humans; Immunoglobulins; Kidney; Male; Prot

1994
Effect of dilazep dihydrochloride on plasma P-selectin concentrations in patients with IgA nephropathy.
    Nephron, 2000, Volume: 85, Issue:3

    Topics: Adult; Case-Control Studies; Dilazep; Glomerulonephritis, IGA; Humans; Middle Aged; P-Selectin; Plat

2000
Effect of dilazep hydrochlorideon the Im munohistopathology of IgA nephropathy in ddY mice.
    Nephron, 2000, Volume: 86, Issue:3

    Topics: Animals; Collagen; Dilazep; Female; Fibronectins; Fluorescent Antibody Technique; Glomerular Mesangi

2000