dilazep has been researched along with Coronary Heart Disease in 22 studies
Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess whether dilazep reduces myocardial necrosis we assigned 72 rats that survived coronary artery occlusion to 3 groups." | 7.66 | Dilazep-induced reduction of ischemic necrosis in rats with coronary artery occlusion. ( Ambrosio, G; Brevetti, G; Cataffo, A; Chiariello, M; Condorelli, M; Genovese, A, 1983) |
| "To assess whether dilazep reduces myocardial necrosis we assigned 72 rats that survived coronary artery occlusion to 3 groups." | 3.66 | Dilazep-induced reduction of ischemic necrosis in rats with coronary artery occlusion. ( Ambrosio, G; Brevetti, G; Cataffo, A; Chiariello, M; Condorelli, M; Genovese, A, 1983) |
| "Systolic intervals, heart rate (HR) and blood pressure (BP) were monitored before and after oral administration of dilazep in 28 patients with chronic coronary disease." | 3.66 | [Cardiodynamic changes induced with dilazep in chronic coronary insufficiency]. ( Fogari, R, 1980) |
| "Dilazep (10(-5) M) was administered in the perfusate either 20 minutes before ischaemia or only during post-ischaemic reperfusion." | 1.27 | Mechanism of myocardial protective action of dilazep during ischaemia and reperfusion. ( Albertini, A; Cargnoni, A; Ceconi, C; Condorelli, E; Curello, S; Ferrari, R, 1987) |
| "Dilazep was injected i." | 1.27 | Effect of dilazep on decrease in myocardial pH during ischemia in dogs. ( Abiko, Y; Fujisawa, Y; Fukushi, Y; Haga, N; Miura, I, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shida, H | 2 |
| Kobayashi, M | 2 |
| Chiba, S | 2 |
| Padeletti, L | 1 |
| Michelucci, A | 1 |
| Giomi, A | 1 |
| Fradella, GA | 1 |
| Monizzi, D | 1 |
| Fantini, F | 1 |
| Chiariello, M | 1 |
| Brevetti, G | 1 |
| Genovese, A | 1 |
| Cataffo, A | 1 |
| Ambrosio, G | 1 |
| Condorelli, M | 1 |
| Pasotti, C | 1 |
| Gandolfi, P | 1 |
| Ottolenghi, L | 1 |
| Pirani, R | 1 |
| Gruppillo, P | 1 |
| Fogari, R | 1 |
| Sone, T | 1 |
| Kobayashi, T | 1 |
| Mizutani, K | 1 |
| Yamamoto, M | 2 |
| Watanabe, T | 1 |
| Parenti, B | 1 |
| Selvaggi, R | 1 |
| Kuzuya, F | 1 |
| Pollter, J | 5 |
| Schnitker, J | 4 |
| Baldrighi, V | 1 |
| Barbaresi, F | 1 |
| Plancher, AC | 1 |
| Portioli, I | 1 |
| Gillner, H | 1 |
| Sievers, HG | 1 |
| Zylmann, G | 1 |
| Bremer, P | 1 |
| Dölle, P | 1 |
| Schumacher, KM | 1 |
| Morishita, T | 1 |
| Arai, C | 1 |
| Abe, N | 1 |
| Takeuchi, K | 1 |
| Hasegawa, M | 1 |
| Takayama, Y | 1 |
| Emori, I | 1 |
| Yoshinori, K | 1 |
| Cargnoni, A | 1 |
| Condorelli, E | 1 |
| Ceconi, C | 1 |
| Curello, S | 1 |
| Albertini, A | 1 |
| Ferrari, R | 1 |
| Ibba, GV | 1 |
| Terrosu, P | 1 |
| Franceschino, V | 1 |
| Contini, GM | 1 |
| Haga, N | 1 |
| Miura, I | 1 |
| Fujisawa, Y | 1 |
| Fukushi, Y | 1 |
| Abiko, Y | 1 |
| Kawamura, H | 1 |
| Kodama, H | 1 |
| Takeuchi, G | 1 |
| Kohsaka, K | 1 |
| Suzuki, S | 1 |
| Nitta, M | 1 |
| Takada, K | 1 |
| Mitomo, Y | 1 |
| Koshu, M | 1 |
| Sugimoto, T | 1 |
| Terada, Y | 1 |
| Uraoka, T | 1 |
1 review available for dilazep and Coronary Heart Disease
| Article | Year |
|---|---|
[Dilazep].
Topics: Animals; Azepines; Cardiovascular System; Coronary Circulation; Coronary Disease; Dilazep; Dogs; Hea | 1980 |
5 trials available for dilazep and Coronary Heart Disease
| Article | Year |
|---|---|
[Therapy of coronary heart disease using Cormelian-Digotab: influence of the duration of therapy. 2. Field study by 107 physicians].
Topics: Azepines; Clinical Trials as Topic; Coronary Disease; Digoxin; Dilazep; Drug Combinations; Heart Fai | 1976 |
[Polycentric and hemodynamic experimentation with a new coronary active drug: dilazep].
Topics: Adult; Aged; Azepines; Clinical Trials as Topic; Coronary Disease; Dilazep; Drug Evaluation; Female; | 1976 |
[Efficiency of Cormelian in coronary insufficiency. Results of a double-blind study].
Topics: Adult; Aged; Angina Pectoris; Azepines; Clinical Trials as Topic; Coronary Disease; Dilazep; Female; | 1975 |
[Administration of cormelian in coronary insufficiency. Results of a double blind study].
Topics: Azepines; Clinical Trials as Topic; Coronary Disease; Dilazep; Humans | 1975 |
[Results of the clinical testing of a new coronary drug, Cormelian].
Topics: Adult; Azepines; Cardiac Volume; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; D | 1972 |
16 other studies available for dilazep and Coronary Heart Disease
| Article | Year |
|---|---|
Effect of dilazep on myocardial contractility following acute ischemia and reperfusion in isolated blood-perfused canine left ventricular muscle.
Topics: Animals; Azepines; Calcium; Cardiomegaly; Coronary Disease; Dilazep; Dogs; Female; Hypothermia, Indu | 1981 |
Intracardiac electrophysiologic study of dilazep in man.
Topics: Adult; Aged; Azepines; Coronary Disease; Dilazep; Electrophysiology; Female; Heart; Humans; Male; Mi | 1984 |
Dilazep-induced reduction of ischemic necrosis in rats with coronary artery occlusion.
Topics: Animals; Azepines; Coronary Circulation; Coronary Disease; Dilazep; Male; Myocardial Infarction; Nec | 1983 |
Contemporaneous administration of digitalis and dilazep to subjects with heart failure of ischemic etiology.
Topics: Aged; Azepines; Blood Pressure; Coronary Disease; Digitalis Glycosides; Dilazep; Drug Interactions; | 1983 |
[Myocardial protection by dilazep in myocardial ischemia and reperfusion].
Topics: Animals; Azepines; Body Temperature; Calcium; Coronary Disease; Dilazep; Dogs; Heart; Heart Arrest; | 1981 |
[Cardiodynamic changes induced with dilazep in chronic coronary insufficiency].
Topics: Adult; Aged; Azepines; Chronic Disease; Coronary Disease; Dilazep; Heart; Heart Rate; Humans; Male; | 1980 |
A study on the noninvasive evaluation of coronary vasodilating drugs with Thallium-201 myocardial imagings.
Topics: Adult; Angina Pectoris; Cardiac Output; Coronary Circulation; Coronary Disease; Coronary Vessels; Di | 1981 |
[Polygraphic and electrocardiographic study of a new coronary therapeutic agent: dilazep].
Topics: Adult; Aged; Azepines; Coronary Disease; Dilazep; Electrocardiography; Exercise Test; Female; Heart | 1980 |
Effects of dilazep (AS-05) on human blood platelet aggregation.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Azepines; Coronary Disease; Dilazep; Female; Humans; | 1979 |
[Therapy of coronary heart disease using Cormelian-Digotab. First communication on a field experiment of 107 residential physicians].
Topics: Adult; Aged; Azepines; Coronary Disease; Digoxin; Dilazep; Drug Combinations; Drug Evaluation; Femal | 1975 |
[Noninvasive quantitative evaluation of cardiac reverse--effects of dilazep (adenosine like agent)].
Topics: Administration, Oral; Azepines; Coronary Disease; Dilazep; Drug Evaluation; Exercise Test; Heart; He | 1988 |
Mechanism of myocardial protective action of dilazep during ischaemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Azepines; Calcium; Coronary Circulation; Coronary Disease; Dilazep; | 1987 |
Cardiovascular effects of a single high dose of dilazep by oral route.
Topics: Administration, Oral; Adult; Angina Pectoris; Angina, Unstable; Azepines; Cardiac Catheterization; C | 1986 |
Effect of dilazep on decrease in myocardial pH during ischemia in dogs.
Topics: Animals; Azepines; Coronary Disease; Dilazep; Dogs; Female; Hydrogen-Ion Concentration; Male; Myocar | 1986 |
[Antiplatelet therapy and platelet function studies in elderly patients with ischemic heart disease--evaluation of whole blood platelet aggregation].
Topics: Aged; Aged, 80 and over; Azepines; Coronary Disease; Dilazep; Female; Humans; Male; Platelet Adhesiv | 1986 |
Effect of dilazep on hemoglobin-oxygen affinity in patients with ischemic heart disease.
Topics: 2,3-Diphosphoglycerate; Administration, Oral; Adult; Aged; Aldosterone; Angina Pectoris; Azepines; C | 1985 |