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dilazep and Brain Ischemia

dilazep has been researched along with Brain Ischemia in 4 studies

Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"r-CBF was reduced by 40% during cerebral ischemia."5.26[Effects of dilazep on cerebral blood flow under normal conditions and recirculation impairment after cerebral ischemia (author's transl)]. ( Kawada, M; Kondo, S; Sano, N, 1981)
"Dilazep has been reported to inhibit edema formation in cerebral ischemia model of spontaneously hypertensive rats."1.28Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. ( Abe, K; Igarashi, N; Ikuta, J; Kawagoe, J; Kogure, K; Shimizu, S; Yamauchi, Y, 1992)
"r-CBF was reduced by 40% during cerebral ischemia."1.26[Effects of dilazep on cerebral blood flow under normal conditions and recirculation impairment after cerebral ischemia (author's transl)]. ( Kawada, M; Kondo, S; Sano, N, 1981)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, T1
Liu, B1
Li, P1
Kondo, S1
Kawada, M1
Sano, N1
Kawagoe, J1
Abe, K1
Ikuta, J2
Igarashi, N1
Shimizu, S2
Yamauchi, Y2
Kogure, K1
Nakamura, M1

Other Studies

4 other studies available for dilazep and Brain Ischemia

ArticleYear
Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Oct-08, Volume: 21

    Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Caspase 3; Cell Su

2015
[Effects of dilazep on cerebral blood flow under normal conditions and recirculation impairment after cerebral ischemia (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:2

    Topics: Animals; Azepines; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Dis

1981
Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Dilazep; Evans Blue; Male; Rats; Rats, Inbred S

1992
[Effect of dilazep dihydrochloride on ischemia and reperfusion-induced cerebral injury in spontaneously hypertensive rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 95, Issue:5

    Topics: Animals; Azepines; Body Water; Brain; Brain Ischemia; Dilazep; Infusions, Intravenous; Lipid Peroxid

1990