dilazep has been researched along with Blood Pressure, High in 4 studies
Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dilazep, a coronary vasodilating drug with adenosine-mediated activity, was tested (acute double-blind study versus placebo) for its antihypertensive activity in 12 patients who had mild to moderate hypertension." | 5.06 | Intravenous dilazep reduces blood pressure and peripheral vascular resistance in humans. ( Carnovali, M; Masotti, G; Poggesi, L; Serneri, GG, 1988) |
| "Dilazep did not produce any significant changes in heart rate and blood pressure after a single oral dose or during chronic dosing." | 1.28 | Therapeutic tolerance, hemodynamic effects, and oral dose kinetics of dilazep dihydrochloride in hypertensive patients. ( Gudenzi, M; Kannan, R; Ookhtens, M; Sambhi, MP; Thananopavarn, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, T | 1 |
| Abe, K | 1 |
| Tokumura, M | 1 |
| Hirono, S | 1 |
| Haruna, M | 1 |
| Ibii, N | 1 |
| Kuriyama, S | 1 |
| Tomonari, H | 1 |
| Hosoya, T | 1 |
| Sambhi, MP | 1 |
| Kannan, R | 1 |
| Thananopavarn, C | 1 |
| Ookhtens, M | 1 |
| Gudenzi, M | 1 |
| Poggesi, L | 1 |
| Masotti, G | 1 |
| Serneri, GG | 1 |
| Carnovali, M | 1 |
1 trial available for dilazep and Blood Pressure, High
| Article | Year |
|---|---|
Intravenous dilazep reduces blood pressure and peripheral vascular resistance in humans.
Topics: Adult; Azepines; Blood Pressure; Clinical Trials as Topic; Dilazep; Double-Blind Method; Female; Hum | 1988 |
3 other studies available for dilazep and Blood Pressure, High
| Article | Year |
|---|---|
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertensio | 2004 |
Antiplatelet therapy decreases the incidence of erythropoietin-induced hypertension in predialysis patients.
Topics: Adult; Aged; Anemia; Dilazep; Dipyridamole; Erythropoietin; Female; Hematocrit; Humans; Hypertension | 1999 |
Therapeutic tolerance, hemodynamic effects, and oral dose kinetics of dilazep dihydrochloride in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Azepines; Blood Pressure; Dilazep; Drug Tolerance; Heart Rate; Hu | 1989 |