Page last updated: 2024-10-26

dilazep and Antiphospholipid Syndrome

dilazep has been researched along with Antiphospholipid Syndrome in 2 studies

Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.

Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

Research Excerpts

ExcerptRelevanceReference
"To investigate whether antiplatelet agents, dilazep and dipyridamole, inhibit tissue factor (TF) expression on monocytes induced by IgG from patients with antiphospholipid syndrome (APS)."7.72Dilazep and dipyridamole inhibit tissue factor expression on monocytes induced by IgG from patients with antiphospholipid syndrome. ( Zhou, H, 2004)
"To investigate whether antiplatelet agents, dilazep and dipyridamole, inhibit tissue factor (TF) expression on monocytes induced by IgG from patients with antiphospholipid syndrome (APS)."3.72Dilazep and dipyridamole inhibit tissue factor expression on monocytes induced by IgG from patients with antiphospholipid syndrome. ( Zhou, H, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, H2
Wolberg, AS1
Roubey, RA1

Other Studies

2 other studies available for dilazep and Antiphospholipid Syndrome

ArticleYear
Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep.
    Blood, 2004, Oct-15, Volume: 104, Issue:8

    Topics: Antibodies, Antiphospholipid; Antibodies, Monoclonal; Antiphospholipid Syndrome; beta 2-Glycoprotein

2004
Dilazep and dipyridamole inhibit tissue factor expression on monocytes induced by IgG from patients with antiphospholipid syndrome.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:10

    Topics: Adrenergic Antagonists; Antiphospholipid Syndrome; Cell Separation; Dilazep; Dipyridamole; Gene Expr

2004