dilazep has been researched along with Angina Pectoris in 7 studies
Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both nifedipine alone (15-60 mg) and in combination with dilazep (50 mg) three times a day produced a significant reduction in angina attacks, consumption of nitroglycerin tablets and increased exercise tolerance." | 6.67 | Controlled clinical trial of nifedipine alone and in combination with dilazep in patients with angina pectoris. ( Biswas, NR; Pandhi, P; Sharma, PL; Wahi, PL, 1991) |
| " Both propranolol alone (20-80 mg) and in combination with dilazep (50 mg) three times a day produced a significant reduction in anginal attacks, consumption of nitroglycerin tablets and increased exercise tolerance." | 6.67 | Controlled clinical trial of propranolol alone and in combination with dilazep in patients with angina pectoris. ( Biswas, NR; Pandhi, P; Sharma, PL; Wahi, PL, 1990) |
| " Both nifedipine alone (15-60 mg) and in combination with dilazep (50 mg) three times a day produced a significant reduction in angina attacks, consumption of nitroglycerin tablets and increased exercise tolerance." | 2.67 | Controlled clinical trial of nifedipine alone and in combination with dilazep in patients with angina pectoris. ( Biswas, NR; Pandhi, P; Sharma, PL; Wahi, PL, 1991) |
| " Both propranolol alone (20-80 mg) and in combination with dilazep (50 mg) three times a day produced a significant reduction in anginal attacks, consumption of nitroglycerin tablets and increased exercise tolerance." | 2.67 | Controlled clinical trial of propranolol alone and in combination with dilazep in patients with angina pectoris. ( Biswas, NR; Pandhi, P; Sharma, PL; Wahi, PL, 1990) |
| "nifedipine (N) was evaluated in 50 outpatients with effort angina; 26 were treated with dilazep 300 mg/die and 24 with nifedipine 30 mg/die." | 2.65 | [Dilazep vs. nifedipine in patients with stable effort angina. A double blind randomized study (author's transl)]. ( Giusti, C; Regoli, F, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Regoli, F | 1 |
| Giusti, C | 1 |
| Sone, T | 1 |
| Kobayashi, T | 1 |
| Mizutani, K | 1 |
| Yamamoto, M | 1 |
| Watanabe, T | 1 |
| Gillner, H | 1 |
| Pollter, J | 1 |
| Schnitker, J | 1 |
| Sievers, HG | 1 |
| Zylmann, G | 1 |
| Pandhi, P | 2 |
| Biswas, NR | 2 |
| Wahi, PL | 2 |
| Sharma, PL | 2 |
| Ibba, GV | 1 |
| Terrosu, P | 1 |
| Franceschino, V | 1 |
| Contini, GM | 1 |
| Koshu, M | 1 |
| Sugimoto, T | 1 |
| Terada, Y | 1 |
| Uraoka, T | 1 |
4 trials available for dilazep and Angina Pectoris
| Article | Year |
|---|---|
[Dilazep vs. nifedipine in patients with stable effort angina. A double blind randomized study (author's transl)].
Topics: Aged; Angina Pectoris; Azepines; Blood Pressure; Clinical Trials as Topic; Dilazep; Double-Blind Met | 1981 |
[Efficiency of Cormelian in coronary insufficiency. Results of a double-blind study].
Topics: Adult; Aged; Angina Pectoris; Azepines; Clinical Trials as Topic; Coronary Disease; Dilazep; Female; | 1975 |
Controlled clinical trial of nifedipine alone and in combination with dilazep in patients with angina pectoris.
Topics: Angina Pectoris; Dilazep; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Midd | 1991 |
Controlled clinical trial of propranolol alone and in combination with dilazep in patients with angina pectoris.
Topics: Angina Pectoris; Azepines; Clinical Trials as Topic; Coronary Circulation; Dilazep; Drug Therapy, Co | 1990 |
3 other studies available for dilazep and Angina Pectoris
| Article | Year |
|---|---|
A study on the noninvasive evaluation of coronary vasodilating drugs with Thallium-201 myocardial imagings.
Topics: Adult; Angina Pectoris; Cardiac Output; Coronary Circulation; Coronary Disease; Coronary Vessels; Di | 1981 |
Cardiovascular effects of a single high dose of dilazep by oral route.
Topics: Administration, Oral; Adult; Angina Pectoris; Angina, Unstable; Azepines; Cardiac Catheterization; C | 1986 |
Effect of dilazep on hemoglobin-oxygen affinity in patients with ischemic heart disease.
Topics: 2,3-Diphosphoglycerate; Administration, Oral; Adult; Aged; Aldosterone; Angina Pectoris; Azepines; C | 1985 |