diisopropanolnitrosamine has been researched along with Adenocarcinoma in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (46.77) | 18.7374 |
| 1990's | 7 (11.29) | 18.2507 |
| 2000's | 23 (37.10) | 29.6817 |
| 2010's | 3 (4.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imaida, K; Kinouch, S; Kishi, S; Nakano, Y; Ninomiya, F; Saoo, K; Tanizawa, J; Yamakawa, K; Yokohira, M | 1 |
| Fukushima, N; Furukawa, M; Honoki, K; Hotta, M; Obo, Y; Tsujiuchi, T; Yamada, T; Yamasaki, A | 1 |
| Fujii, M; Honoki, K; Okabe, K; Tajiri, M; Tsujino, M; Tsujiuchi, T; Wakabayashi, N | 1 |
| Blyth, BJ; Doi, K; Iwata, K; Kakinuma, S; Morioka, T; Nakata, A; Nishimura, M; Oghiso, Y; Shimada, Y; Tani, S; Yamada, Y | 1 |
| Konishi, Y; Sasaki, Y; Tsujiuchi, T; Tsutsumi, M | 6 |
| Mimeoka, A; Otani, S; Shiraki, K; Une, K; Watanabe, H; Yano, R | 1 |
| Kuniyasu, H; Oka, Y; Sasaki, Y; Tsujiuchi, T; Tsutsumi, M | 1 |
| Hirose, M; Ikeda, T; Imazawa, T; Kimura, S; Nishikawa, A; Okazaki, K; Son, HY; Umemura, T | 1 |
| Hanaoka, M; Hinotsume, D; Honoki, K; Kato, A; Shigemura, M; Shimizu, K; Shimoichi, Y; Tsujiuchi, T | 1 |
| Fujii, H; Honoki, K; Kato, A; Shimizu, K; Shimoichi, Y; Tsujiuchi, T | 1 |
| Fujii, H; Honoki, K; Kato, A; Shigemura, M; Shimizu, K; Tsujiuchi, T | 1 |
| Fujii, H; Hinotsume, D; Honoki, K; Itsuzaki, Y; Shimizu, K; Shimoichi, Y; Tsujiuchi, T | 1 |
| Hayama, M; Kamiya, K; Kashimoto, N; Watanabe, H | 1 |
| Fujii, H; Honoki, K; Masaoka, T; Onishi, M; Shimizu, K; Sugata, E; Tsujiuchi, T | 1 |
| Crooks, PA; Nakshatri, H; Neelakantan, S; Ralstin, M; Schmidt, CM; Sweeney, CJ; Vegeler, RC; Wu, H; Yip-Schneider, MT | 1 |
| Mori, C; Nishikawa, T; Onishi, M; Saito, M; Shimizu, K; Sokuza, Y; Sugata, E; Tsujiuchi, T | 1 |
| Hirose, M; Ikawa, E; Ito, N; Masuda, A; Shirai, T | 1 |
| Marsh, WH; Parsa, I; Sutton, AL | 1 |
| Nagel, D; Pour, P; Salmasi, S; Wallcave, L | 1 |
| Mohr, U; Reznik, G | 2 |
| Kato, Y; Mukai, R; Satake, K; Shim, K; Umeyama, K | 1 |
| Monno, S | 1 |
| Denda, A; Katsuragi, M; Konishi, Y; Makino, T; Murata, Y; Namiki, M; Obara, T; Ueda, N; Yokose, Y | 1 |
| Pour, PM; Salmasi, SZ | 1 |
| Hamashima, Y; Miyazaki, K; Takasan, H | 1 |
| Flaks, A; Flaks, B; Moore, MA | 3 |
| Hamashima, Y; Miyazaki, K; Takasan, H; Tobe, T | 1 |
| Denda, A; Konishi, Y; Maruyama, H; Matsui, M; Mori, Y; Takahashi, S; Toyoshi, K; Yokose, Y | 1 |
| Fukuda, I; Ishikawa, O; Iwanaga, T; Matsui, Y; Terasawa, T; Wada, A | 1 |
| Klöppel, G; Pracht, B; Rückert, K | 1 |
| Asano, N; Imamura, T; Manabe, T; Ohshio, G; Suwa, H; Yoshimura, T | 1 |
| Fukuda, T; Kitada, H; Konsihi, Y; Narita, N; Takahama, M; Tsujiuchi, T; Tsutsumi, M | 1 |
| Ahn, B; Han, BS; Hasegawa, R; Ito, N; Kim, DJ; Shirai, T; Tsuda, H | 1 |
| Ikematsu, S; Iki, K; Kadomatsu, K; Konishi, Y; Muramatsu, T; Sakaki, T; Sakitani, H; Sakuma, S; Takahama, M; Tsujiuchi, T; Tsutsumi, M | 1 |
| Iki, K; Kido, A; Kitamura, S; Konishi, Y; Sakitani, H; Takahama, M; Taniguchi, S; Tsujiuchi, T; Tsutsumi, M | 1 |
| Kitada, H; Konishi, Y; Murakawa, K; Sakitani, H; Sasaki, Y; Shiraiwa, K; Takahama, M; Tsujiuchi, T; Tsutsumi, M; Yoshimoto, M | 1 |
| Konishi, Y; Murata, N; Sasaki, Y; Tsujiuchi, T; Tsutsumi, M | 1 |
| Konishi, Y; Kusuoka, O; Masutani, M; Nakagama, H; Nozaki, T; Sugimura, T; Suzuki, H; Tsujiuchi, T; Tsutsumi, M | 1 |
| Konishi, Y; Murata, N; Nakae, D; Sasaki, Y; Tsujiuchi, T; Tsutsumi, M | 2 |
| Harris, CC; Kingsbury, E; Levitt, MH; Mollelo, C; Newkirk, C; Springer, S; Squire, R; Thomas, D; Wenk, M | 1 |
| Asai, T; Ichikawa, M; Kajikawa, M; Kimoto, E; Naito, Y; Nakazawa, S; Sano, H; Suzuki, Y; Walton, D | 1 |
| Denda, A; Kondo, H; Konishi, Y; Takahashi, S | 1 |
| Kubota, Y; Moto-o, N; Nishimura, N; Saito, S; Taguchi, K; Tanaka, M; Watanabe, A; Yamazaki, K | 1 |
| Takemoto, K; Yoshimura, H | 1 |
| Kato, Y; Mukai, R; Satake, K; Umeyama, K | 1 |
| Ito, S; Katsuragi, M; Konishi, Y; Matsuzaki, M; Obara, T; Tsutsumi, M; Ura, H | 1 |
| Kokkinakis, DM; Scarpelli, DG | 1 |
| Kitazawa, S; Konishi, Y; Matsuzaki, M; Mizumoto, K; Natori, T; Tsutsumi, M | 1 |
| Bannasch, P; Hacker, HJ; Ito, N; Moore, MA; Sato, K; Tsuda, H | 1 |
| Eimoto, H; Konishi, Y; Nakajima, A; Shiraiwa, K; Tamura, K; Tsutsumi, M; Yamamoto, K; Yokose, Y | 1 |
| Yamamoto, H | 1 |
| Ito, S; Katsuragi, M; Konishi, Y; Makino, T; Obara, T; Ohishi, G; Uchida, H; Ura, H; Yoshiya, K | 1 |
| Ichimiya, H; Ito, S; Kamano, T; Kinugasa, T; Konishi, Y; Makino, T; Tsutsumi, M; Ura, H | 1 |
62 other study(ies) available for diisopropanolnitrosamine and Adenocarcinoma
| Article | Year |
|---|---|
Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenoma; Animals; Aspartic Acid Endopeptidases; Biomarkers, Tumor; Bronchioles; Hyperplasia; Immunohistochemistry; Lung; Lung Neoplasms; Nitrosamines; Prognosis; Pulmonary Alveoli; Rats; Rats, Inbred F344 | 2014 |
Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Mutational Analysis; Lung Neoplasms; Male; Mutation; Nitrosamines; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Receptors, Lysophosphatidic Acid | 2009 |
Alterations of the LKB1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; AMP-Activated Protein Kinase Kinases; Animals; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Male; Mutation; Nitrosamines; Protein Serine-Threonine Kinases; Rats; Rats, Wistar | 2010 |
Co-operative effects of thoracic X-ray irradiation and N-nitrosobis(2-hydroxypropyl) amine administration on lung tumorigenesis in neonatal, juvenile and adult Wistar rats.
Topics: Adenocarcinoma; Adenoma; Aging; Animals; Animals, Newborn; Carcinogens; Cell Transformation, Neoplastic; Female; Lung Neoplasms; Neoplasms, Radiation-Induced; Nitrosamines; Rats; Rats, Wistar; Thorax | 2013 |
Alterations of the retinoblastoma-related gene RB2/p130 in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Blotting, Northern; Blotting, Western; DNA Mutational Analysis; DNA Primers; Genes, Retinoblastoma; Lung Neoplasms; Male; Mutagens; Nitrosamines; Phosphoproteins; Polymorphism, Single-Stranded Conformational; Proteins; Rats; Rats, Wistar; Retinoblastoma Protein; Retinoblastoma-Like Protein p130; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Alterations of the M6p/Igf2 receptor gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogens; DNA Primers; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Inhibition by long-term fermented miso of induction of pulmonary adenocarcinoma by diisopropanolnitrosamine in Wistar rats.
Topics: Adenocarcinoma; Animals; Diet; Fermentation; Glycine max; Lung Neoplasms; Male; Nitrosamines; Organ Size; Rats; Rats, Wistar | 2003 |
Alterations of the Dutt1/Robo1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Carcinogens; Cell Transformation, Neoplastic; Lung Neoplasms; Male; Molecular Sequence Data; Nerve Tissue Proteins; Nitrosamines; Rats; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Roundabout Proteins; Tumor Suppressor Proteins | 2004 |
Pronounced synergistic promotion of N-bis(2-hydroxypropyl)nitrosamine-initiated thyroid tumorigenesis in rats treated with excess soybean and iodine-deficient diets.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Diet; Female; Glycine max; Iodine; Male; Nitrosamines; Rats; Rats, Inbred F344; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triiodothyronine; Tumor Burden | 2005 |
Reduced expressions of Foxp1 and Rassf1a genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Down-Regulation; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar; Repressor Proteins; RNA, Messenger; Tumor Suppressor Proteins | 2006 |
Aberrant DNA methylation of E-cadherin and p16 genes in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Cadherins; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, p16; Lung; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar; Reference Values; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Aberrant methylation patterns of the Rassf1a gene in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Base Sequence; DNA Methylation; Lung; Lung Neoplasms; Male; Molecular Sequence Data; Mutation; Nitrosamines; Rats; Reference Values; Tumor Suppressor Proteins | 2006 |
Reduced expression of the Connexin26 gene and its aberrant DNA methylation in rat lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Connexin 26; Connexins; DNA Methylation; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar | 2006 |
Inhibitory effect of a water-soluble extract from the culture medium of Ganoderma lucidum (Rei-shi) mycelia on the development of pulmonary adenocarcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Wistar rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Culture Media; Diet; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Immunohistochemistry; Lung Neoplasms; Male; Mycelium; Nitrosamines; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Reishi | 2006 |
Hypermethylation of the Dal-1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: 5' Flanking Region; Adenocarcinoma; Animals; DNA Methylation; Lung Neoplasms; Male; Membrane Proteins; Nitrosamines; Rats; Rats, Wistar; RNA, Messenger; Tumor Suppressor Proteins | 2007 |
Effect of celecoxib and novel agent LC-1 in a hamster model of lung cancer.
Topics: Adenocarcinoma; Animals; Carcinogens; Celecoxib; Cricetinae; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Lung; Lung Neoplasms; Mesocricetus; NF-kappa B; Nitrosamines; Pyrazoles; Random Allocation; Sesquiterpenes; Sulfonamides | 2007 |
Numerical changes in the mitochondrial DNA displacement loop in lung lesions induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Adenoma; Animals; DNA, Mitochondrial; Hyperplasia; Lung; Lung Neoplasms; Male; Mutagens; Mutation; Nitrosamines; Rats; Rats, Wistar | 2008 |
Enhancement of N-bis(2-hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane.
Topics: Adenocarcinoma; Animals; Bleomycin; Carcinogens; Drug Synergism; Hyperplasia; Lung; Lung Neoplasms; Male; Nitrosamines; Nitrosomethylurethane; Rats; Rats, Inbred F344; Time Factors; Urethane | 1984 |
An in vitro model of pancreas carcinoma: N-nitroso-bis(2-hydroxypropyl)amine effects.
Topics: Adenocarcinoma; Adenoma; Adenoma, Islet Cell; Animals; Carcinogens; Culture Techniques; Disease Models, Animal; Female; Fetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Placenta; Pregnancy; Rats; Time Factors | 1980 |
Induction of local epidermal papillomas and carcinoma by selected nitrosamines.
Topics: Adenocarcinoma; Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Carcinoma; Cricetinae; Female; Head and Neck Neoplasms; Liver Neoplasms; Mesocricetus; Nitrosamines; Nose Neoplasms; Pancreatic Neoplasms; Papilloma; Skin Neoplasms | 1980 |
Tumours of the pancreas.
Topics: Adenocarcinoma; Adenoma; Adenoma, Islet Cell; Animals; Cricetinae; Mesocricetus; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1982 |
Experimental pancreatic carcinoma as a model of human pancreatic carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenocarcinoma, Papillary; Animals; Cricetinae; Disease Models, Animal; Humans; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Rats; Rats, Inbred Strains | 1984 |
[Histogenesis and implications of the pancreatic pseudoductules in experimental pancreatic carcinogenesis of hamster induced by N-nitrosobis (2-hydroxypropyl) amine].
Topics: Adenocarcinoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Male; Mesocricetus; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms | 1984 |
Enzyme histochemical studies on transplantable pancreatic adenocarcinomas in Syrian golden hamsters.
Topics: Adenocarcinoma; Animals; Cricetinae; Histocytochemistry; Male; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms | 1984 |
Comparative studies of neoplastic response to a single dose of nitroso compounds. The effect of N-nitrosobis (2-hydroxypropyl)amine in Syrian golden hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cricetinae; Female; Gallbladder Neoplasms; Kidney Neoplasms; Liver Neoplasms; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Time Factors | 1982 |
Histochemical elucidation of hamster pancreatic carcinogenesis induced by N-nitroso-bis (2-hydroxypropyl) amine.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Female; Histocytochemistry; Hyperplasia; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1982 |
Ultrastructural analysis of pancreatic carcinogenesis. V. Changes in differentiation of acinar cells during chronic treatment with N-nitrosobis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Endoplasmic Reticulum; Golgi Apparatus; Male; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Time Factors | 1982 |
The histogenesis of hamster pancreatic cancer induced by N-nitroso-bis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Cricetinae; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1982 |
Organotropic effect of N-nitroso-bis-(2-hydroxypropyl)-amine: production of lung adenocarcinoma in rats by a single intraperitoneal injection.
Topics: Adenocarcinoma; Animals; Autoradiography; Carcinogens; Injections, Intraperitoneal; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred Strains | 1982 |
[Histological characteristics of pancreatic carcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Syrian golden hamster].
Topics: Adenocarcinoma; Animals; Cricetinae; Female; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1982 |
Differences in experimental pancreatic carcinogenesis induced by oral or subcutaneous administration of 2,2'-dihydroxydi-n-propylnitrosamine in duct-ligated hamsters.
Topics: Adenocarcinoma; Administration, Oral; Animals; Cricetinae; Female; Injections, Subcutaneous; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Precancerous Conditions | 1981 |
Ultrastructural analysis of pancreatic carcinogenesis: morphological characterization of N-nitroso-bis(2-hydroxypropyl)amine-induced neoplasms in the Syrian hamster.
Topics: Adenocarcinoma; Animals; Carcinogens; Cricetinae; Cystadenoma; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1980 |
Effect of synthetic protease inhibitor on histologic changes and free radical activity in hamsters with pancreatic cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Animals; Carcinogens; Cricetinae; Esters; Free Radical Scavengers; Gabexate; Glutathione Peroxidase; Guanidines; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Superoxide Dismutase; Trypsin Inhibitors | 1993 |
Frequent mutations of Ki-ras but no mutations of Ha-ras and p53 in lung lesions induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA Primers; Genes, p53; Genes, ras; Lung Neoplasms; Male; Molecular Sequence Data; Mutagens; Mutation; Nitrosamines; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Tumor Suppressor Protein p53 | 1996 |
Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Drug Synergism; Indoles; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Sprague-Dawley; Thyroid Neoplasms | 1997 |
Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progression.
Topics: Adenocarcinoma; Animals; Base Sequence; Blotting, Northern; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cytokines; DNA Primers; Female; Immunohistochemistry; Lung Neoplasms; Male; Midkine; Nitrosamines; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Expression of vascular endothelial growth factor and its receptors during lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Blotting, Northern; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Endothelial Growth Factors; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Lung Diseases; Lung Neoplasms; Lymphokines; Male; Neoplasm Proteins; Neovascularization, Pathologic; Nitrosamines; Precancerous Conditions; Proto-Oncogene Proteins; Pulmonary Alveoli; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; RNA, Neoplasm; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 1999 |
Inhibitory effects of combined administration of antibiotics and anti-inflammatory drugs on lung tumor development initiated by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Carcinogens; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Erythromycin; Gene Expression Regulation; Inflammation; Lung Neoplasms; Macrophages; Male; Neutrophils; Nitrosamines; Penicillins; Piroxicam; Plant Extracts; Pneumonia, Bacterial; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Specific Pathogen-Free Organisms | 2000 |
Elevated expression of interleukins in lung adenocarcinomas induced by N-Nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Disease Models, Animal; Disease Progression; Interleukins; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar | 2000 |
Mutations of the Smad2 and Smad4 genes in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; DNA-Binding Proteins; Lung Neoplasms; Male; Mutation; Nitrosamines; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Smad2 Protein; Smad4 Protein; Trans-Activators | 2000 |
Mutations and reduced expression of the transforming growth factor-beta receptor II gene in rat lung adenocarcinomas induced by N-nitrosobis-(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Carcinogens; Gene Expression; Lung Neoplasms; Male; Mutation; Nitrosamines; Polymorphism, Single-Stranded Conformational; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transforming Growth Factor beta | 2000 |
Mutations of adenomatous polyposis coli and beta-catenin genes during progression of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Adenoma; Animals; beta Catenin; Carcinogens; Cytoskeletal Proteins; Disease Progression; DNA Mutational Analysis; Genes, APC; Immunohistochemistry; Lung Neoplasms; Male; Mutagens; Mutation, Missense; Nitrosamines; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Signal Transduction; Trans-Activators; Transcription Factors | 2000 |
Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Lung Neoplasms; Male; Mutation; Nitrosamines; Phosphoric Monoester Hydrolases; Polymorphism, Single-Stranded Conformational; PTEN Phosphohydrolase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2001 |
Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Disease Susceptibility; Hemangioma; Hemangiosarcoma; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Nitrosamines; Poly(ADP-ribose) Polymerases | 2001 |
Ultrastructural analysis of pancreatic carcinogenesis. III. Multifocal cystic lesions induced by N-nitroso-bis(2-hydroxypropyl)amine in the hamster exocrine pancreas.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Differentiation; Cricetinae; Disease Progression; Humans; Male; Mesocricetus; Microscopy, Electron; Nitrosamines; Pancreas; Pancreatic Cyst; Pancreatic Neoplasms; Precancerous Conditions | 1980 |
Elevated expression of transforming growth factor betas and the tumor necrosis factor family in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Disease Models, Animal; Drinking; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Wistar; RNA, Messenger; RNA, Neoplasm; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
FHIT alterations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Topics: Acid Anhydride Hydrolases; Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Carcinogens; Exons; Lung Neoplasms; Male; Molecular Sequence Data; Mutagenesis; Mutagens; Neoplasm Proteins; Nitrosamines; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Carcinogenic effect of di-isopropanolnitrosamine on the rat thyroid gland.
Topics: Adenocarcinoma; Animals; Carcinogens; Female; Lethal Dose 50; Male; Nitrosamines; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyroid Neoplasms | 1977 |
Experimental pancreatic carcinogenesis. I. Morphogenesis of pancreatic adenocarcinoma in the Syrian golden hamster induced by N-nitroso-bis(2-hydroxypropyl)amine.
Topics: Adenocarcinoma; Animals; Cricetinae; Cystadenoma; Epithelial Cells; Epithelium; Islets of Langerhans; Male; Neoplasms, Experimental; Nitrosamines; Pancreatic Ducts; Pancreatic Neoplasms; Time Factors | 1977 |
RNase levels in golden hamster with DHPN induced pancreatic cancer.
Topics: Adenocarcinoma; Animals; Cricetinae; Liver; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreas; Pancreatic Neoplasms; Propylamines; Ribonucleases | 1979 |
Lung carcinomas induced by oral administration of N-bis(2-hydroxypropyl)nitrosamine in rats.
Topics: Adenocarcinoma; Adenoma; Administration, Oral; Animals; Body Weight; Carcinoma, Squamous Cell; Kidney; Liver; Lung; Lung Neoplasms; Male; Nitrosamines; Organ Size; Rats | 1976 |
Cell-kinetic analysis of pancreatic cancers in Syrian golden hamsters.
Topics: Adenocarcinoma; Animals; Bromodeoxyuridine; Cell Cycle; Cricetinae; Female; Immunohistochemistry; Kinetics; Male; Mesocricetus; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Tumor Cells, Cultured | 1991 |
[Effect of cigarette smoking and/or N-bis(2-hydroxypropyl)nitrosamine (DHPN) on the development of lung and pleural tumors in rats induced by administration of asbestos].
Topics: Adenocarcinoma; Animals; Asbestosis; Carcinogens; Cocarcinogenesis; Lung Neoplasms; Male; Mesothelioma; Nitrosamines; Pleural Neoplasms; Rats; Rats, Inbred Strains; Smoking | 1991 |
Effects of cerulein on the normal pancreas and on experimental pancreatic carcinoma in the Syrian golden hamster.
Topics: Adenocarcinoma; Amylases; Animals; Ceruletide; Cricetinae; Disease Models, Animal; DNA; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreas; Pancreatic Neoplasms | 1986 |
Pancreatic tumor antigen in transplantable adenocarcinomas induced by N-bis(2-hydroxypropyl)nitrosamine in hamsters.
Topics: Adenocarcinoma; Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Carcinogens; Chromatography, Affinity; Cricetinae; Electrophoresis, Agar Gel; Immunoenzyme Techniques; Male; Mesocricetus; Molecular Weight; Neoplasm Transplantation; Nitrosamines; Pancreatic Neoplasms; Rabbits; Staining and Labeling | 1987 |
Carcinogenicity of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine, N-nitrosobis(2-hydroxypropyl)amine and cis-N-nitroso-2,6-dimethylmorpholine administered continuously in the Syrian hamster, and the effect of dietary protein on N-nitroso(2-hydroxypropyl)(2
Topics: Adenocarcinoma; Animals; Cricetinae; Dietary Proteins; Disease Models, Animal; Liver Neoplasms; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Rats; Rats, Inbred Strains | 1989 |
Intracellular distribution of pancreatic tumor antigen purified from BHP-induced adenocarcinomas in Syrian hamsters.
Topics: Adenocarcinoma; Amino Acids; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Cricetinae; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1989 |
Altered enzyme expression in propylnitrosamine-induced Syrian hamster lung lesions.
Topics: Adenocarcinoma; Adenoma; Animals; Autoradiography; Carcinogens; Cricetinae; Cystadenoma; Immunoenzyme Techniques; Lung Diseases; Lung Neoplasms; Mesocricetus; Microscopy, Electron; Nitrosamines | 1987 |
Comparative histochemical investigation of the glutathione S-transferase placental form and gamma-glutamyltranspeptidase during N-nitrosobis(2-hydroxypropyl)amine-induced lung carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; gamma-Glutamyltransferase; Glutathione Transferase; Hyperplasia; Immunohistochemistry; Lung; Lung Neoplasms; Male; Metaplasia; Nitrosamines; Placenta; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
Tumorigenesis and cystic lesion of the liver by N-bis(2-hydroxypropyl)nitrosamine in ddY mice.
Topics: Adenocarcinoma; Adenoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Cysts; Hemangioma; Liver Neoplasms; Lung Neoplasms; Male; Mice; Nitrosamines | 1985 |
Vascular changes associated with growth of primary and transplantable pancreatic adenocarcinomas induced in Syrian golden hamsters by N-nitrosobis(2-oxopropyl)amine (BOP) and N-nitrosobis(2-hydroxypropyl)amine (BHP).
Topics: Adenocarcinoma; Angiography; Animals; Blood Vessels; Cricetinae; Injections, Subcutaneous; Male; Mathematics; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms | 1986 |
Combined effects of cholecystectomy and lithocholic acid on pancreatic carcinogenesis of N-nitrosobis(2-hydroxypropyl)amine in Syrian golden hamsters.
Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Carcinoma; Carcinoma in Situ; Cholecystectomy; Cricetinae; Lithocholic Acid; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms | 1986 |