dihydroxyphenylalanine has been researched along with Syndrome in 39 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Unaffected, mutation-positive relatives of index patients with hereditary paraganglioma syndromes were offered PET imaging with [(18)F]fluorodihydroxyphenylalanine and the incidence of pathological findings was retrospectively analysed in relation to mutations of the succinate dehydrogenase enzyme complex." | 7.79 | High incidence of extraadrenal paraganglioma in families with SDHx syndromes detected by functional imaging with [18F]fluorodihydroxyphenylalanine PET. ( Bartsch, O; Fottner, C; Helisch, A; Lackner, KJ; Mann, WJ; Miederer, M; Musholt, TJ; Papaspyrou, K; Rossmann, H; Schreckenberger, M; Weber, MM, 2013) |
| "Unaffected, mutation-positive relatives of index patients with hereditary paraganglioma syndromes were offered PET imaging with [(18)F]fluorodihydroxyphenylalanine and the incidence of pathological findings was retrospectively analysed in relation to mutations of the succinate dehydrogenase enzyme complex." | 3.79 | High incidence of extraadrenal paraganglioma in families with SDHx syndromes detected by functional imaging with [18F]fluorodihydroxyphenylalanine PET. ( Bartsch, O; Fottner, C; Helisch, A; Lackner, KJ; Mann, WJ; Miederer, M; Musholt, TJ; Papaspyrou, K; Rossmann, H; Schreckenberger, M; Weber, MM, 2013) |
| "We estimated regional and global metabolic rates for glucose using 18F-fluorodeoxyglucose (FDG) and PET in six patients with hemiparkinsonism-hemiatrophy syndrome (HPHA; mean age, 41." | 3.69 | Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome. ( Chaly, T; Dhawan, V; Eidelberg, D; Fahn, S; Giladi, N; Ishikawa, T; Przedborski, S; Spetsieris, P; Takikawa, S, 1994) |
| "Transient exposure to the toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces a syndrome resembling idiopathic parkinsonism (IP)." | 3.69 | Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions. ( Calne, DB; Langston, JW; Schulzer, M; Snow, BJ; Tetrud, JW; Vingerhoets, FJ, 1994) |
| "The Segawa syndrome is an autosomal dominant form of guanosine triphosphate cyclohydrolase deficiency, resulting in decreased dopamine and serotonin levels, typically presenting as a dopa-responsive dystonia." | 1.35 | Uneventful electroconvulsive therapy in a patient with dopa-responsive dystonia (Segawa syndrome). ( Peuskens, J; Rooseleer, J; Sienaert, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (69.23) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 3 (7.69) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Béreau, M | 1 |
| Van Waes, V | 1 |
| Servant, M | 1 |
| Magnin, E | 1 |
| Tatu, L | 1 |
| Anheim, M | 1 |
| Sienaert, P | 1 |
| Rooseleer, J | 1 |
| Peuskens, J | 1 |
| Levine, DS | 1 |
| Metzger, DL | 1 |
| Nadel, HR | 1 |
| Oviedo, A | 1 |
| Adam, MJ | 1 |
| Skarsgard, E | 1 |
| Dill, P | 1 |
| Schneider, J | 1 |
| Weber, P | 1 |
| Trachsel, D | 1 |
| Tekin, M | 1 |
| Jakobs, C | 1 |
| Thöny, B | 1 |
| Blau, N | 1 |
| Miederer, M | 1 |
| Fottner, C | 1 |
| Rossmann, H | 1 |
| Helisch, A | 1 |
| Papaspyrou, K | 1 |
| Bartsch, O | 1 |
| Mann, WJ | 1 |
| Musholt, TJ | 1 |
| Weber, MM | 1 |
| Lackner, KJ | 1 |
| Schreckenberger, M | 1 |
| Goldstein, DS | 1 |
| Holmes, C | 1 |
| Frank, SM | 1 |
| Dendi, R | 1 |
| Cannon, RO | 1 |
| Sharabi, Y | 1 |
| Esler, MD | 1 |
| Eisenhofer, G | 1 |
| Brink, I | 1 |
| Schaefer, O | 1 |
| Walz, M | 1 |
| Neumann, HP | 1 |
| Krupenina, LB | 1 |
| Vinogradov, MV | 1 |
| Badalian, LO | 1 |
| Temin, PA | 1 |
| Dzhabarov, BD | 1 |
| Bespalova, VA | 1 |
| Kret, LA | 1 |
| Magalov, ShI | 1 |
| Dadali, EL | 1 |
| Arushanian, EB | 1 |
| Dutov, AA | 1 |
| Anokhina, IP | 1 |
| Kogan, BM | 1 |
| Przedborski, S | 1 |
| Giladi, N | 1 |
| Takikawa, S | 1 |
| Ishikawa, T | 1 |
| Dhawan, V | 1 |
| Spetsieris, P | 1 |
| Chaly, T | 1 |
| Fahn, S | 1 |
| Eidelberg, D | 1 |
| Vingerhoets, FJ | 1 |
| Snow, BJ | 1 |
| Tetrud, JW | 1 |
| Langston, JW | 1 |
| Schulzer, M | 1 |
| Calne, DB | 1 |
| Turjanski, N | 1 |
| Lees, AJ | 1 |
| Brooks, DJ | 2 |
| Popkova, EV | 1 |
| Krupina, NA | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Orlova, IN | 1 |
| Iordanskaia, TE | 1 |
| Mishima, Y | 1 |
| Barkatova, VP | 1 |
| Strelkova, NI | 1 |
| Shchepina, TP | 1 |
| Lupandin, VM | 1 |
| Lando, LI | 1 |
| Gromova, EA | 1 |
| Kamenskaia, VM | 1 |
| Zykov, MB | 1 |
| Mosunova, TG | 1 |
| Sawle, GV | 1 |
| Marsden, CD | 1 |
| Frackowiak, RS | 1 |
| Patton, MA | 1 |
| Baraitser, M | 1 |
| Heagerty, AH | 1 |
| Eady, RA | 1 |
| Piasetskaia, MV | 1 |
| Bragina, NN | 1 |
| Il'icheva, RF | 1 |
| Potapov, AA | 1 |
| Leonardi, G | 1 |
| Soyka, D | 1 |
| Jaffe, RB | 1 |
| Yuen, BH | 1 |
| Keye, WR | 1 |
| Midgley, AR | 1 |
| Lance, JW | 1 |
| Andrews, C | 1 |
| Donaldson, IM | 1 |
| Zárate, A | 2 |
| Jacobs, LS | 1 |
| Canales, ES | 2 |
| Schally, AV | 1 |
| De la Cruz, A | 1 |
| Soria, J | 2 |
| Daughaday, WH | 1 |
| Varga, L | 1 |
| Wenner, R | 1 |
| Del Pozo, E | 1 |
| Schneider, KW | 1 |
| Vaisrub, S | 1 |
| Mastaglia, FL | 1 |
| Grainger, K | 1 |
| Kee, F | 1 |
| Sadka, M | 1 |
| Lefroy, R | 1 |
| Lhermitte, F | 1 |
| Chain, F | 1 |
| Escourolle, R | 1 |
| Chedru, F | 1 |
| Guilleminault, C | 1 |
| Francoual, M | 1 |
| Maneiro, PJ | 1 |
| MacGregor, C | 1 |
| Strauss, RG | 1 |
| Sharpe, J | 1 |
| Marquez-Julio, A | 1 |
| Ashby, P | 1 |
| Edmonds, M | 1 |
| Friesen, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Laboratory Evaluation of Chronic Orthostatic Intolerance[NCT00069693] | 200 participants | Observational | 2003-09-26 | Completed | |||
| Propranolol for Syncope With Sympathoadrenal Imbalance[NCT00060866] | Phase 4 | 24 participants | Interventional | 2003-05-31 | Completed | ||
| Propranolol for Syncope With Sympathoadrenal Imbalance in Children[NCT00093860] | Phase 2 | 50 participants | Interventional | 2004-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dihydroxyphenylalanine and Syndrome
| Article | Year |
|---|---|
Apathy in Parkinson's Disease: Clinical Patterns and Neurobiological Basis.
Topics: Apathy; Depression; Dihydroxyphenylalanine; Humans; Limbic System; Parkinson Disease; Syndrome | 2023 |
[Nigrostriatal system as a source of torsion extrapyramidal disorders (review)].
Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Basal Ganglia Diseases; Cats; Caudate Nucleus; Corpus S | 1980 |
1 trial available for dihydroxyphenylalanine and Syndrome
| Article | Year |
|---|---|
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Autonomic Nervous System Diseases; Chronic Disease; | 2002 |
36 other studies available for dihydroxyphenylalanine and Syndrome
| Article | Year |
|---|---|
Uneventful electroconvulsive therapy in a patient with dopa-responsive dystonia (Segawa syndrome).
Topics: Affective Disorders, Psychotic; Delusions; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Electr | 2009 |
Novel use of F-DOPA PET/CT imaging in a child with paraganglioma/pheochromocytoma syndrome.
Topics: Adolescent; Adrenal Gland Neoplasms; Dihydroxyphenylalanine; Female; Humans; Kidney Neoplasms; Multi | 2011 |
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM).
Topics: Base Sequence; Child; Codon, Nonsense; Congenital Abnormalities; Congenital Microtia; Dihydroxypheny | 2011 |
High incidence of extraadrenal paraganglioma in families with SDHx syndromes detected by functional imaging with [18F]fluorodihydroxyphenylalanine PET.
Topics: Adolescent; Adult; Child; Dihydroxyphenylalanine; False Negative Reactions; Female; Germ-Line Mutati | 2013 |
Fluorine-18 DOPA PET imaging of paraganglioma syndrome.
Topics: Abdominal Neoplasms; Child; Dihydroxyphenylalanine; Head and Neck Neoplasms; Humans; Male; Paragangl | 2006 |
[State of the adrenergic and cholinergic systems of schizophrenic patients during the process of psychopharmacotherapy].
Topics: Acetylcholine; Acetylcholinesterase; Adult; Antipsychotic Agents; Catecholamines; Dihydroxyphenylala | 1980 |
[Catecholamine concentration in the blood and excretion in the urine in different forms of progressive muscular dystrophy].
Topics: Adolescent; Adult; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Middle Age | 1984 |
[Catecholamine metabolism in Huntington's chorea (in patients and their phenotypically healthy relatives)].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Dopamine; Epinephrine; Femal | 1980 |
[Various features of dopamine metabolism in schizophrenia].
Topics: Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Humans; Norepinephrine; Schizophre | 1981 |
Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome.
Topics: Adult; Atrophy; Brain; Deoxyglucose; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Glucose | 1994 |
Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihyd | 1994 |
Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies.
Topics: Aged; Carbon Radioisotopes; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Humans; Kinet | 1999 |
[Monoamine level in the rat brain with MPTP-induced depressive syndrome].
Topics: Animals; Biogenic Monoamines; Brain; Depressive Disorder; Dihydroxyphenylalanine; Dopamine; Dopamine | 1999 |
Histopathology of functional pigmentary disorders.
Topics: Albinism; Animals; Cricetinae; Dihydroxyphenylalanine; Female; Humans; Infant; Melanocytes; Melanosi | 1978 |
[Catecholamine excretion in torsion dystonia].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Dopamine; Dystonia Musculoru | 1978 |
[Humeroscapular periarthritis in patients with cervical osteochondrosis].
Topics: Autonomic Nervous System; Brachial Plexus Neuritis; Cervical Vertebrae; Contracture; Dihydroxyphenyl | 1978 |
[Role of biogenic amines in the pathogenesis of intellectual disorders in children with minimal psychoorganic syndromes].
Topics: Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Dihydroxyphenylalanine; Electr | 1978 |
[Catecholamines metabolism in extrapyramidal disorders in children].
Topics: Adolescent; Ataxia Telangiectasia; Basal Ganglia Diseases; Catecholamines; Child; Child, Preschool; | 1977 |
Corticobasal degeneration. A unique pattern of regional cortical oxygen hypometabolism and striatal fluorodopa uptake demonstrated by positron emission tomography.
Topics: Aged; Animals; Apraxias; Brain Diseases; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; E | 1991 |
An oculocerebral hypopigmentation syndrome: a case report with clinical, histochemical, and ultrastructural findings.
Topics: Cerebellar Ataxia; Child, Preschool; Dihydroxyphenylalanine; Humans; Intellectual Disability; Male; | 1987 |
[Use of L-DOPA in the complex treatment of severe craniocerebral injuries].
Topics: Adolescent; Adult; Brain Injuries; Child; Combined Modality Therapy; Dihydroxyphenylalanine; Dopamin | 1987 |
Letter: Acetylcholine poisoning and sympathetic overactivity in tetanus.
Topics: Acetylcholine; Cholinesterase Inhibitors; Curare; Dihydroxyphenylalanine; Humans; Sympathetic Nervou | 1974 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |
Physiologic and pathologic profiles of circulating human prolactin.
Topics: Adenoma, Chromophobe; Adult; Amenorrhea; Chorionic Gonadotropin; Dihydroxyphenylalanine; Ethinyl Est | 1973 |
Dysaesthesia-dyskinesia: a syndrome of painful legs and moving toes.
Topics: Aged; Amantadine; Amitriptyline; Chlorpromazine; Dihydroxyphenylalanine; Female; Humans; Leg; Moveme | 1973 |
The treatment of progressive supranuclear palsy with L-dopa.
Topics: Aged; Bulbar Palsy, Progressive; Demyelinating Diseases; Dihydroxyphenylalanine; Female; Humans; Mid | 1973 |
Functional evaluation of pituitary reserve in patients with the amenorrhea-galactorrhea syndrome utilizing luteinizing hormone-releasing hormone (LH-RH), L-dopa and chlorpromazine.
Topics: Adult; Amenorrhea; Chlorpromazine; Dihydroxyphenylalanine; Female; Follicle Stimulating Hormone; Gon | 1973 |
Treatment of galactorrhea-amenorrhea syndrome with Br-ergocryptine (CB 154): restoration of ovulatory function and fertility.
Topics: Adult; Amenorrhea; Bromine; Clomiphene; Dihydroxyphenylalanine; Ergot Alkaloids; Estrogens; Female; | 1973 |
[Etiology and therapy of the parotid gland syndrome].
Topics: Antihypertensive Agents; Chewing Gum; Clonidine; Dihydroxyphenylalanine; Eating; Humans; Neostigmine | 1973 |
Dementia dialytica.
Topics: Autopsy; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Electroenceph | 1973 |
Progressive supranuclear palsy (the Steele-Richardson-Olszewski syndrome) clinical and electrophysiological observations in eleven cases.
Topics: Aged; Basal Ganglia Diseases; Bulbar Palsy, Progressive; Demyelinating Diseases; Dihydroxyphenylalan | 1973 |
[A further case of tetanus-like contracture distinct from the stiff man syndrome. Pharmacological and neuropathological study of a case of predominantly spinal encephalomyelitis].
Topics: Aged; Carbamazepine; Contracture; Diazepam; Dihydroxyphenylalanine; Electromyography; Encephalomyeli | 1973 |
Effect of acute administration of L-dopa on serum concentrations of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in patients with the amenorrhea-galactorrhea syndrome.
Topics: Administration, Oral; Adult; Amenorrhea; Dihydroxyphenylalanine; Female; Follicle Stimulating Hormon | 1973 |
Failure of methyldopa therapy in Bartter's syndrome.
Topics: Child; Depression, Chemical; Dihydroxyphenylalanine; Humans; Hyperaldosteronism; Hypokalemia; Juxtag | 1974 |
Idiopathic orthostatic hypotension treated with levodopa and MAO inhibitor: a preliminary report.
Topics: Basal Ganglia Diseases; Brain Stem; Catecholamines; Dihydroxyphenylalanine; Drug Synergism; Fecal In | 1972 |
The effect of levodopa on galactorrhea in the Forbes-Albright syndrome.
Topics: Adenoma, Chromophobe; Adult; Dihydroxyphenylalanine; Female; Growth Hormone; Humans; Hysterectomy; L | 1972 |