dihydroxyphenylalanine has been researched along with Syncope in 4 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "One problem with DOPA therapy for Parkinson's disease is its cardiovascular side effects including hypotension and syncope, the underlying mechanisms of which are largely unknown." | 2.50 | Cardiovascular actions of DOPA mediated by the gene product of ocular albinism 1. ( Chen, S; Goshima, Y; Koga, M; Masukawa, D; Nakamura, F, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goshima, Y | 1 |
| Nakamura, F | 1 |
| Masukawa, D | 1 |
| Chen, S | 1 |
| Koga, M | 1 |
| Lu, CC | 1 |
| Diedrich, A | 1 |
| Tung, CS | 1 |
| Paranjape, SY | 1 |
| Harris, PA | 1 |
| Byrne, DW | 1 |
| Jordan, J | 1 |
| Robertson, D | 1 |
| Nifontova, LA | 1 |
| O'Doherty, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Drinking Water on the Pressor Response to Pseudoephedrine in Patients With Autonomic Failure[NCT02149901] | Early Phase 1 | 35 participants (Anticipated) | Interventional | 2014-10-31 | Terminated (stopped due to funding terminated) | ||
| The Effect of Water Carbonation on Orthostatic Tolerance[NCT05621460] | 25 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dihydroxyphenylalanine and Syncope
| Article | Year |
|---|---|
Cardiovascular actions of DOPA mediated by the gene product of ocular albinism 1.
Topics: Animals; Baroreflex; Dihydroxyphenylalanine; Eye Proteins; Humans; Hypotension; Membrane Glycoprotei | 2014 |
1 trial available for dihydroxyphenylalanine and Syncope
| Article | Year |
|---|---|
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
Water ingestion as prophylaxis against syncope.
Topics: Adolescent; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Female; Heart Rate; Humans; Hypotensi | 2003 |
2 other studies available for dihydroxyphenylalanine and Syncope
| Article | Year |
|---|---|
[Increased predisposition to syncope in vasovagal syncope].
Topics: Adult; Anxiety; Blood Vessels; Cardiovascular Diseases; Corticosterone; Dihydroxyphenylalanine; Epin | 1980 |
Levodopa in treating Parkinsonism.
Topics: Adult; Aged; Athetosis; Dihydroxyphenylalanine; Female; Humans; Hypotension; Male; Middle Aged; Naus | 1971 |