dihydroxyphenylalanine has been researched along with Subarachnoid Hemorrhage in 6 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Seven months later he developed a left rest tremor associated with mild bilateral extrapyramidal symptoms and responsive to levodopa treatment." | 3.69 | Rest tremor and extrapyramidal symptoms after midbrain haemorrhage: clinical and 18F-dopa PET evaluation. ( Defer, GL; Degos, JD; Malapert, D; Remy, P; Ricolfi, F; Samson, Y, 1994) |
| "Patients with Parkinson's disease have a decrement in homovanillic acid that is reversed by treatment with L-3,4-dihydroxyphenylalanine." | 1.27 | Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method. ( Aguado, EG; de Yebenes, JG; Mena, MA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moussouttas, M | 2 |
| Lai, EW | 2 |
| Dombrowski, K | 2 |
| Huynh, TT | 2 |
| Khoury, J | 2 |
| Carmona, G | 1 |
| DeCaro, M | 1 |
| Pacak, K | 2 |
| Lambert, G | 2 |
| Naredi, S | 1 |
| Edén, E | 1 |
| Rydenhag, B | 1 |
| Friberg, P | 1 |
| Mena, MA | 1 |
| Aguado, EG | 1 |
| de Yebenes, JG | 1 |
| Defer, GL | 1 |
| Remy, P | 1 |
| Malapert, D | 1 |
| Ricolfi, F | 1 |
| Samson, Y | 1 |
| Degos, JD | 1 |
| Lambert, E | 1 |
| Hastings, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Myocardial Dysfunction at Early Phase of Traumatic Brain Injury : Evaluation by Two Dimensional and Speckle Tracking Transthoracic Echocardiography[NCT02380482] | 40 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for dihydroxyphenylalanine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
CSF catecholamine profile in subarachnoid hemorrhage patients with neurogenic cardiomyopathy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Cardiomyopathies; Catecholamines; Dihydroxyphenylalanine; Dopa | 2011 |
Determinants of central sympathetic activation in spontaneous primary subarachnoid hemorrhage.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Critical Illness; Dihydroxyphenylala | 2012 |
Monoamine metabolism and sympathetic nervous activation following subarachnoid haemorrhage: influence of gender and hydrocephalus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Biogenic Monoamines; Craniocerebral Trauma; Dihydroxyph | 2002 |
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; | 1984 |
Rest tremor and extrapyramidal symptoms after midbrain haemorrhage: clinical and 18F-dopa PET evaluation.
Topics: Adult; Basal Ganglia Diseases; Dihydroxyphenylalanine; Electromyography; Fluorine Radioisotopes; Hum | 1994 |
Noradrenaline synthesis, release and vesicular transport in the rat brain following subarachnoid haemorrhage.
Topics: Animals; Dihydroxyphenylalanine; Hypothalamus; Male; Medulla Oblongata; Methoxyhydroxyphenylglycol; | 2001 |