dihydroxyphenylalanine has been researched along with Skin Neoplasms in 85 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Homovanillic acid (HVA) was determined both in 45 patients with different forms of melanoma and those hospitalized on the suspicion of melanoma and in 15 healthy persons." | 8.75 | Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin. ( Ivanova, VD; Raushenbakh, MO; Trapeznikov, NN; Yavorsky, VV, 1975) |
| "To develop a biochemical diagnosis for malignant melanomas, 5-S-cysteinyldopa in the tissues of malignant melanomas and other pigmented tumors were quantitatively analysed." | 7.67 | [Biochemical diagnoses of malignant melanomas with determinations of 5-S-cysteinyldopa in lesions]. ( Morishima, T; Sameshima, T, 1989) |
| "In case of uncharacteristic patient complaints or slightly pathologic BSR or liver enzyme levels in patients, suffering from melanoma, the determination of 5-S-cysteinyldopa in the 24-h-urine may be of great diagnostic value." | 7.66 | [5-S-cysteinyldopa determination in the urine. Its value for monitoring in melanoma patients]. ( Graef, V; Hellwich, M; Paul, E; Ruppel, R, 1983) |
| "Cysteinyldopas and Dopa in the urine and tissues of Japanese melanoma patients were investigated quantitatively by means of high-performance liquid chromatography." | 7.66 | Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma. ( Fujita, M; Fukada, E; Hanawa, S; Morishima, T; Nagashima, N; Saito, M; Tatsumi, F, 1983) |
| "In a total of 1,828 determinations, urinary excretion of 5-S-Cysteinyldopa was studied over a period of three years in 384 patients treated for melanoma or with metastases of malignant melanoma." | 7.66 | [5-S-cysteinyldopa in the urine - a "tumor test" for malignant melanoma? Comparison with the usual laboratory examinations]. ( Graef, V; Paul, E; Ruppel, R, 1980) |
| "The effect of dopa, cysteine, and glutathione on 5-S-cysteinyldopa (5-S-CD) genesis in melanoma cells cultured in normal and tyrosine- and cysteine-free media has been studied." | 7.66 | Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro. ( Ichihashi, M; Mishima, Y; Mojamdar, M, 1982) |
| "Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas." | 7.66 | Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas. ( Agrup, G; Hansson, C; Rorsman, H; Rosengren, AM; Rosengren, E, 1978) |
| "Determinations of the urinary excretion of 5-S-cysteinyldopa were performed in 571 patients previously treated by surgery for melanoma or melanoma metastasis." | 7.66 | 5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis. ( Agrup, G; Agrup, P; Andersson, T; Hafström, L; Hansson, C; Jacobsson, S; Jönsson, PE; Rorsman, H; Rosengren, AM; Rosengren, E, 1979) |
| "Determination of urine cysteinyldopa excretion is the most sensitive chemical test for the detection of melanoma metastases and has been successfully applied during the Scandinavian winter, when sun irradiation is low." | 7.66 | The urinary melanogen cysteinyldopa in melanoma and in suntanning: Australian experience. ( Nixon, PF, 1978) |
| "With the aid of gas chromatography and mass spectrometry a metabolite of dopa, 3-methoxytyrosine, has been demonstrated in the urine of 2 patients with melanoma metastases, the amounts excreted being 4." | 7.65 | Demonstration of 3-methoxytyrosine in the urine of melanoma patients. ( Agrup, G; Bengtsson, M; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E, 1976) |
| "A newly discovered amino acid, 5-S-cysteinyldopa, present in the urine of healthy subjects is excreted in pathological amounts in many patients suffering from melanoma metastases." | 7.65 | 5-S-cysteinyldopa in the urine of melanoma patients. ( Agrup, G; Agrup, P; Andersson, T; Falck, B; Hansson, JA; Jacobsson, S; Rorsman, H; Rosengren, AM; Rosengren, E, 1977) |
| "Unexpectedly, B16 melanoma cells exposed to IB-MECA increased melanin levels in a dose-dependent manner." | 5.39 | Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants. ( Korenstein, R; Madi, L; Nyska, A; Rosenberg-Haggen, B, 2013) |
| "Homovanillic acid (HVA) was determined both in 45 patients with different forms of melanoma and those hospitalized on the suspicion of melanoma and in 15 healthy persons." | 4.75 | Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin. ( Ivanova, VD; Raushenbakh, MO; Trapeznikov, NN; Yavorsky, VV, 1975) |
| " To address this issue, the levels of CysH and GSH were varied in normal melanocytes and melanoma cells using buthionine sulfoximine (BSO), an inhibitor of GSH biosynthesis." | 3.70 | Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione. ( Benathan, M; Furumura, M; Hearing, VJ; Kobayashi, N; Panizzon, RG; Virador, V, 1999) |
| "To develop a biochemical diagnosis for malignant melanomas, 5-S-cysteinyldopa in the tissues of malignant melanomas and other pigmented tumors were quantitatively analysed." | 3.67 | [Biochemical diagnoses of malignant melanomas with determinations of 5-S-cysteinyldopa in lesions]. ( Morishima, T; Sameshima, T, 1989) |
| " Carbidopa and DOPA together elevated 5SCD markedly in a dose-dependent manner to values higher than seen in some patients with metastatic malignant melanoma." | 3.66 | Urinary 5-S-cysteinyldopa in Parkinsonism after DOPA and carbidopa. ( Gunder, M; Miller, S; Stewart, RM, 1983) |
| "In case of uncharacteristic patient complaints or slightly pathologic BSR or liver enzyme levels in patients, suffering from melanoma, the determination of 5-S-cysteinyldopa in the 24-h-urine may be of great diagnostic value." | 3.66 | [5-S-cysteinyldopa determination in the urine. Its value for monitoring in melanoma patients]. ( Graef, V; Hellwich, M; Paul, E; Ruppel, R, 1983) |
| "Cysteinyldopas and Dopa in the urine and tissues of Japanese melanoma patients were investigated quantitatively by means of high-performance liquid chromatography." | 3.66 | Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma. ( Fujita, M; Fukada, E; Hanawa, S; Morishima, T; Nagashima, N; Saito, M; Tatsumi, F, 1983) |
| "In a total of 1,828 determinations, urinary excretion of 5-S-Cysteinyldopa was studied over a period of three years in 384 patients treated for melanoma or with metastases of malignant melanoma." | 3.66 | [5-S-cysteinyldopa in the urine - a "tumor test" for malignant melanoma? Comparison with the usual laboratory examinations]. ( Graef, V; Paul, E; Ruppel, R, 1980) |
| "The effect of dopa, cysteine, and glutathione on 5-S-cysteinyldopa (5-S-CD) genesis in melanoma cells cultured in normal and tyrosine- and cysteine-free media has been studied." | 3.66 | Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro. ( Ichihashi, M; Mishima, Y; Mojamdar, M, 1982) |
| "Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas." | 3.66 | Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas. ( Agrup, G; Hansson, C; Rorsman, H; Rosengren, AM; Rosengren, E, 1978) |
| "Determinations of the urinary excretion of 5-S-cysteinyldopa were performed in 571 patients previously treated by surgery for melanoma or melanoma metastasis." | 3.66 | 5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis. ( Agrup, G; Agrup, P; Andersson, T; Hafström, L; Hansson, C; Jacobsson, S; Jönsson, PE; Rorsman, H; Rosengren, AM; Rosengren, E, 1979) |
| "Determination of urine cysteinyldopa excretion is the most sensitive chemical test for the detection of melanoma metastases and has been successfully applied during the Scandinavian winter, when sun irradiation is low." | 3.66 | The urinary melanogen cysteinyldopa in melanoma and in suntanning: Australian experience. ( Nixon, PF, 1978) |
| "With the aid of gas chromatography and mass spectrometry a metabolite of dopa, 3-methoxytyrosine, has been demonstrated in the urine of 2 patients with melanoma metastases, the amounts excreted being 4." | 3.65 | Demonstration of 3-methoxytyrosine in the urine of melanoma patients. ( Agrup, G; Bengtsson, M; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E, 1976) |
| "A newly discovered amino acid, 5-S-cysteinyldopa, present in the urine of healthy subjects is excreted in pathological amounts in many patients suffering from melanoma metastases." | 3.65 | 5-S-cysteinyldopa in the urine of melanoma patients. ( Agrup, G; Agrup, P; Andersson, T; Falck, B; Hansson, JA; Jacobsson, S; Rorsman, H; Rosengren, AM; Rosengren, E, 1977) |
| "Unexpectedly, B16 melanoma cells exposed to IB-MECA increased melanin levels in a dose-dependent manner." | 1.39 | Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants. ( Korenstein, R; Madi, L; Nyska, A; Rosenberg-Haggen, B, 2013) |
| "Cells from dermis and epidermis of Ota's nevus lesions were cultured to obtain the pigment producing cells that are specific epidermal and dermal melanocytes of nevus Ota." | 1.30 | Characterization of melanosomes and melanogenesis in cells cultured from Ota's nevus. ( Aihara, K; Hirayama, T; Kishikawa, T; Sasakia, Y; Suzuki, T, 1997) |
| "The production of metastases and the differentiation of tumors in the present experiments appeared to be related to the genetic background of the mice and the epigenetic metabolic environment of tumors and cells." | 1.28 | Differentiation of new metastatic variants of B16 melanoma under different culture conditions. ( Ali-Mehidi, S; Aubert, C; Rouge, F; Voulot, C, 1992) |
| "Pigmented cells cultured from nevi are quite different." | 1.27 | [Differences in the culture of pigment cells from various sources]. ( Castelli, A; Fimiani, M; Flori, ML; Mancianti, ML; Raffaelli, M; Valentino, A, 1984) |
| "In human melanocytes and benign nevi cells the fluorogenic catechols have so far not been characterized, since chemical analyses are difficult to perform on skin, due to the small amounts of catechols present." | 1.26 | On the occurrence of cysteinyldopa and dopa in melanocytes and benign nevi cells. ( Falck, B; Jacobsson, S; Lindvall, O; Nietsche, UB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (82.35) | 18.7374 |
| 1990's | 8 (9.41) | 18.2507 |
| 2000's | 3 (3.53) | 29.6817 |
| 2010's | 4 (4.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, S | 1 |
| Lin, CM | 1 |
| Xu, Z | 1 |
| Miao, L | 1 |
| Wang, Y | 1 |
| Huang, L | 1 |
| Umemura, H | 1 |
| Yamasaki, O | 1 |
| Kaji, T | 1 |
| Otsuka, M | 1 |
| Asagoe, K | 1 |
| Takata, M | 1 |
| Iwatsuki, K | 1 |
| Ichikawa, A | 1 |
| Takagi, H | 1 |
| Suda, K | 1 |
| Yao, T | 1 |
| Konishi, H | 1 |
| Yamanaka, K | 1 |
| Mizutani, H | 1 |
| Madi, L | 1 |
| Rosenberg-Haggen, B | 1 |
| Nyska, A | 1 |
| Korenstein, R | 1 |
| MIKI, Y | 1 |
| ZELICKSON, AS | 2 |
| HIRSCH, HM | 1 |
| HARTMANN, JF | 1 |
| Masamoto, Y | 1 |
| Murata, Y | 1 |
| Baba, K | 1 |
| Shimoishi, Y | 1 |
| Tada, M | 1 |
| Takahata, K | 1 |
| Seshadri, N | 1 |
| Wat, J | 1 |
| Balan, K | 1 |
| Hu, F | 1 |
| Mojamdar, M | 5 |
| Ichihashi, M | 4 |
| Mishima, Y | 6 |
| Stewart, RM | 1 |
| Miller, S | 1 |
| Gunder, M | 1 |
| Castelli, A | 1 |
| Fimiani, M | 1 |
| Mancianti, ML | 1 |
| Raffaelli, M | 1 |
| Flori, ML | 1 |
| Valentino, A | 1 |
| Paul, E | 3 |
| Graef, V | 2 |
| Ruppel, R | 2 |
| Hellwich, M | 1 |
| Morishima, T | 7 |
| Fukada, E | 4 |
| Nagashima, N | 4 |
| Tatsumi, F | 2 |
| Saito, M | 2 |
| Fujita, M | 2 |
| Hanawa, S | 3 |
| Watanabe, M | 1 |
| Jimbow, K | 2 |
| Miura, S | 1 |
| Ito, Y | 1 |
| Kasuga, T | 1 |
| Ito, S | 3 |
| Sakamoto, F | 1 |
| Ito, M | 1 |
| Yamamoto, A | 1 |
| Sato, Y | 2 |
| Washio, M | 1 |
| Pavel, S | 2 |
| Muskiet, FA | 1 |
| Budesínská, A | 1 |
| Duchon, J | 2 |
| Ichihasi, M | 1 |
| Anderson, RR | 1 |
| Parrish, JA | 1 |
| Inoi, T | 1 |
| de Vries, TJ | 1 |
| Fourkour, A | 1 |
| Wobbes, T | 1 |
| Verkroost, G | 1 |
| Ruiter, DJ | 1 |
| van Muijen, GN | 1 |
| Kishikawa, T | 2 |
| Suzuki, T | 2 |
| Sasakia, Y | 1 |
| Aihara, K | 1 |
| Hirayama, T | 2 |
| Sasaki, Y | 1 |
| Wakamatu, K | 1 |
| Tsukamoto, K | 1 |
| Furue, M | 1 |
| Takayama, O | 1 |
| Akasu, R | 1 |
| Ohtake, N | 1 |
| Wakamatsu, K | 1 |
| Tamaki, K | 1 |
| Shimada, S | 1 |
| Bessou-Touya, S | 1 |
| Morichon, F | 1 |
| Surlève-Bazeille, JE | 1 |
| Bioulac-Sage, P | 1 |
| Pain, C | 1 |
| Taïeb, A | 1 |
| Benathan, M | 1 |
| Virador, V | 1 |
| Furumura, M | 1 |
| Kobayashi, N | 1 |
| Panizzon, RG | 1 |
| Hearing, VJ | 2 |
| Agrup, G | 10 |
| Falck, B | 8 |
| Kennedy, BM | 1 |
| Rorsman, H | 12 |
| Rosengren, AM | 8 |
| Rosengren, E | 9 |
| Andersson, T | 4 |
| Persson, K | 2 |
| Gernand, E | 1 |
| Agrup, P | 3 |
| Jacobsson, S | 5 |
| Bengtsson, M | 1 |
| Hansson, JA | 1 |
| Hansson, C | 2 |
| Hafström, L | 2 |
| Jönsson, PE | 2 |
| Drzewiecki, KT | 1 |
| Nixon, PF | 1 |
| Berkelhammer, J | 1 |
| Caines, SM | 1 |
| Dexter, DL | 1 |
| Adelstein, EH | 1 |
| Oxenhandler, RW | 1 |
| Hook, RR | 1 |
| Hunter, JA | 1 |
| Paterson, WD | 1 |
| Fairley, DJ | 1 |
| Matous, B | 1 |
| Ekel, TM | 1 |
| Pullmann, H | 2 |
| Steigleder, GK | 2 |
| Ishikawa, T | 1 |
| Endo, M | 1 |
| Deppe, R | 1 |
| Lindvall, O | 1 |
| Nietsche, UB | 1 |
| Trapeznikov, NN | 1 |
| Raushenbakh, MO | 1 |
| Ivanova, VD | 1 |
| Yavorsky, VV | 1 |
| Fitzpatrick, TB | 1 |
| Szabo, G | 1 |
| Hori, Y | 1 |
| Césarini, JP | 1 |
| Meunier, M | 1 |
| Aubert, C | 1 |
| Ali-Mehidi, S | 1 |
| Rouge, F | 1 |
| Voulot, C | 1 |
| Hamada, M | 1 |
| Itakura, C | 1 |
| Sameshima, T | 1 |
| Kanematsu, S | 1 |
| Marsch, WC | 1 |
| Ernst, TM | 1 |
| Artuc, M | 1 |
| Stüttgen, G | 1 |
| Beyer, C | 1 |
| Fiedler, H | 1 |
| Wohlrab, W | 1 |
| Wozniak, KD | 1 |
| Wong, CK | 1 |
| Thorne, EG | 1 |
| Mottaz, JH | 1 |
| Vogel, CL | 1 |
| Dhru, D | 1 |
| Bomirski, A | 1 |
| Zawrocka-Wrzolkowa, T | 1 |
| Pautsch, F | 1 |
| Gordeladze, AS | 1 |
| Mevorah, B | 1 |
| Frenk, E | 1 |
| Kocsis, M | 1 |
| Blois, MS | 1 |
| Ivanov, II | 1 |
| Vdovenko, VM | 1 |
| Bobrova, VN | 1 |
| Gavrilenko, IS | 1 |
| Rumiantseva, LN | 1 |
| Robinson, E | 1 |
| Wajsbort, J | 1 |
| Hirshowitz, B | 1 |
| Lieberman, AN | 1 |
| Shupack, JL | 1 |
| Shanin, AP | 1 |
| Jacobson, S | 1 |
| Olivecrona, H | 1 |
| Sohn, N | 1 |
| Gang, H | 1 |
| Gumport, SL | 1 |
| Goldstein, M | 1 |
| Deppisch, LM | 1 |
| Rost, FW | 1 |
| Polak, JM | 1 |
| Pearse, AG | 1 |
| Herrmann, WP | 1 |
| Miyazaki, K | 2 |
| Seiji, M | 3 |
| Skibba, JL | 1 |
| Pinckley, J | 1 |
| Gilbert, EF | 1 |
| Johnson, RO | 1 |
| Maul, GG | 1 |
| Romsdahl, MM | 1 |
| Otaki, N | 1 |
2 reviews available for dihydroxyphenylalanine and Skin Neoplasms
| Article | Year |
|---|---|
Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin.
Topics: Animals; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Lymphatic Metastasis; Melanoma; Phenylac | 1975 |
[A review of the literature concerning the etiology, pathogenesis, histogenesis, clinical picture and treatment of skin melanomas during the past 5 years].
Topics: Carbon Isotopes; Dihydroxyphenylalanine; Golgi Apparatus; Humans; Melanoma; Mitochondria; Nevus; Nev | 1971 |
1 trial available for dihydroxyphenylalanine and Skin Neoplasms
| Article | Year |
|---|---|
[Treatment of malignant melanoma with DTIC--therapeutic effects determined by 5-S-cysteinyldopa changes in the urine (proceedings)].
Topics: Clinical Trials as Topic; Cysteinyldopa; Dacarbazine; Dihydroxyphenylalanine; Drug Evaluation; Human | 1978 |
82 other studies available for dihydroxyphenylalanine and Skin Neoplasms
| Article | Year |
|---|---|
Co-delivery of cisplatin and rapamycin for enhanced anticancer therapy through synergistic effects and microenvironment modulation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chromatography, High Pressure Liquid; C | 2014 |
Usefulness of serum 5-S-cysteinyl-dopa as a biomarker for predicting prognosis and detecting relapse in patients with advanced stage malignant melanoma.
Topics: Biomarkers, Tumor; Cysteinyldopa; Dihydroxyphenylalanine; Feasibility Studies; Female; Follow-Up Stu | 2017 |
New methodological approach for the rapid and sensitive detection of melanocytes and melanocytic tumours. The DOPA-GA method.
Topics: Diagnosis, Differential; Dihydroxyphenylalanine; Glyoxylates; Humans; Melanocytes; Melanoma; Microsc | 2009 |
Possible case for false-positive reaction in serum 5-S-cysteinyldopa levels in a patient with malignant melanoma by ingestion of Agaricus blazei Murrill extract.
Topics: Agaricus; Aged; Biomarkers, Tumor; Dihydroxyphenylalanine; False Positive Reactions; Female; Humans; | 2010 |
Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants.
Topics: Adenosine; Androstadienes; Cell Line, Tumor; Cyclic AMP; Dihydroxyphenylalanine; Humans; In Vitro Te | 2013 |
PIGMENTED BASAL CELL EPITHELIOMA. II. HISTOLOGICAL STUDY.
Topics: Carcinoma, Basal Cell; Chromatophores; Connective Tissue; Dihydroxyphenylalanine; Histocytochemistry | 1963 |
MELANOGENESIS: AN AUTORADIOGRAPHIC STUDY AT THE ULTRASTRUCTURAL LEVEL.
Topics: Animals; Autoradiography; Dihydroxyphenylalanine; Electrons; Histocytochemistry; Melanins; Melanoma; | 1964 |
Inhibitory effects of esculetin on melanin biosynthesis.
Topics: Agaricales; Animals; Cell Line, Tumor; Dihydroxyphenylalanine; Epidermal Cells; Guinea Pigs; Melanin | 2004 |
Bilateral adrenal metastases from malignant melanoma: concordant findings on (18)F-FDG and (18)F-FDOPA PET.
Topics: Adrenal Gland Neoplasms; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Humans; Male; Melanoma; Mid | 2006 |
Theophylline and melanocyte-stimulating hormone effects on gamma-glutamyl transpeptidase and DOPA reactions in cultured melanoma cells.
Topics: Animals; Cell Line; Dihydroxyphenylalanine; gamma-Glutamyltransferase; Melanocyte-Stimulating Hormon | 1982 |
Tyrosinase and gamma-glutamyl transpeptidase in 5-s-cysteinyldopa genesis within melanotic and amelanotic melanomas.
Topics: Catechol Oxidase; Cysteinyldopa; Dihydroxyphenylalanine; Ditiocarb; gamma-Glutamyltransferase; Human | 1982 |
Urinary 5-S-cysteinyldopa in Parkinsonism after DOPA and carbidopa.
Topics: Adult; Aged; Carbidopa; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Melanoma; Middle Aged; Parkin | 1983 |
[Differences in the culture of pigment cells from various sources].
Topics: Carcinoma, Basal Cell; Cells, Cultured; Cyclic AMP; Dihydroxyphenylalanine; Humans; Keratosis; Melan | 1984 |
[5-S-cysteinyldopa determination in the urine. Its value for monitoring in melanoma patients].
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Isomerism; Melanoma; Neoplasm Metastasis; Skin Neopla | 1983 |
[Diagnosis of amelanotic malignant melanoma by means of the fluorescence method (Falck & Hillarp) and determination of 5-S-cysteinyldopa in the lesions].
Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Microscopy, Fluo | 1983 |
Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma.
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Isomerism; Japan; Lymphatic Metastasis; Melanoma; Ski | 1983 |
Studies on amelanotic melanoma with the fluorescence method (Falck and Hillarp) and biochemical analysis of 5-S-cysteinyldopa in the tissues.
Topics: Adult; Aged; Carcinoma, Basal Cell; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Male; Melanoma; M | 1983 |
[Utilization of melanin precursors for experimental chemotherapy of malignant melanoma].
Topics: Animals; Catecholamines; Cysteamine; Cysteine; Dihydroxyphenylalanine; Melanins; Melanocytes; Melano | 1984 |
[Ultrastructural study of eruptive cellular nevi, with special reference to spherical melanosomes].
Topics: Adolescent; Dihydroxyphenylalanine; Female; Humans; Melanocytes; Microscopy, Electron; Nevus; Skin N | 1984 |
[5-S-cysteinyldopa in the urine - a "tumor test" for malignant melanoma? Comparison with the usual laboratory examinations].
Topics: BCG Vaccine; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Melphalan; Neopl | 1980 |
A qualitative gas chromatographic analysis of substituted 5,6-dihydroxyindoles from the urine of patients with melanoma.
Topics: Chromatography, Gas; Dihydroxyphenylalanine; Humans; Indoles; Melanins; Melanoma; Skin Neoplasms | 1981 |
[Urinary 5-S-cysteinyldopa in malignant melanoma subjects-with special reference to melanoma stages and dopa loading test (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanom | 1981 |
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro.
Topics: Animals; Cells, Cultured; Cricetinae; Culture Media; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine | 1982 |
[Contents of cysteinyldopa isomers and DOPA in lesions of malignant melanoma (author's transl)].
Topics: Aged; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Isomerism; Male; Melanoma; Skin Neoplasms | 1982 |
Lasers in dermatology provide a model for exploring new applications in surgical oncology.
Topics: Animals; Black People; Dermatologic Surgical Procedures; Dihydroxyphenylalanine; Hemangioma; Humans; | 1982 |
[Correlation of urinary 5-S-cysteinyldopa with repeated remission of melanoma induced by DTIC combination chemotherapy].
Topics: Cysteinyldopa; Dacarbazine; Dihydroxyphenylalanine; Female; Humans; Lymphoma; Melanoma; Middle Aged; | 1982 |
Heterogeneous expression of immunotherapy candidate proteins gp100, MART-1, and tyrosinase in human melanoma cell lines and in human melanocytic lesions.
Topics: Antigens, Neoplasm; Dihydroxyphenylalanine; gp100 Melanoma Antigen; Humans; Immunohistochemistry; MA | 1997 |
Characterization of melanosomes and melanogenesis in cells cultured from Ota's nevus.
Topics: Dihydroxyphenylalanine; Humans; Melanocytes; Microscopy, Electron; Nevus of Ota; Skin Neoplasms; Tum | 1997 |
A role of SH-compounds in maturation of melanosomes in cells cultured from nevus Ota.
Topics: Cell Differentiation; Cysteine; Dihydroxyphenylalanine; Glutathione; Humans; Lysosomes; Melanins; Me | 1998 |
Generalized melanosis in metastatic malignant melanoma: the possible role of DOPAquinone metabolites.
Topics: Aged; Benzoquinones; Dihydroxyphenylalanine; Fatal Outcome; Genital Neoplasms, Male; Humans; Male; M | 1998 |
An ex vivo study of congenital pigmented nevi in epidermal reconstructs.
Topics: Cells, Cultured; Child; Culture Techniques; Dihydroxyphenylalanine; Humans; Immunohistochemistry; Ke | 1999 |
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathion | 1999 |
Formation of cysteinyldopa from glutathionedopa in melanoma.
Topics: Animals; Cysteine; Depression, Chemical; Dihydroxyphenylalanine; Glutathione; Guinea Pigs; Humans; K | 1975 |
5-S-cysteinyldopa in the plasma of melanoma patients and the renal clearance of this amino acid.
Topics: Adult; Breast Neoplasms; Cysteine; Dihydroxyphenylalanine; Humans; Liver Neoplasms; Lung Neoplasms; | 1975 |
Increase of melanocytes around malignant melanoma.
Topics: Adult; Aged; Cell Count; Dihydroxyphenylalanine; Female; Humans; Male; Melanocytes; Melanoma; Middle | 1975 |
Urinary excretion of 5-S-cysteinyldopa in patients with primary melanoma or melanoma metastasis.
Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm | 1975 |
Demonstration of 3-methoxytyrosine in the urine of melanoma patients.
Topics: Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Mass Spectrometry; Mela | 1976 |
5-S-cysteinyldopa in the urine of melanoma patients.
Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Eye Neoplasms; Female; Humans; Male; Melanoma; M | 1977 |
Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas.
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Melanoma; Skin Neoplasms | 1978 |
5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis.
Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Hair Color; Humans; Lymphatic Metastasis | 1979 |
Detection and quantitation of 5-S-cysteinyldopa in melanotic and amelanotic melanoma in comparison with nonpigment cell tumors and it's urinary excretion.
Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Middle Aged; Ski | 1979 |
The epidermal melanocyte system in patients with malignant melanoma. Quantitative and qualitative investigation of dopa positive melanocytes.
Topics: Cell Count; Cell Transformation, Neoplastic; Dihydroxyphenylalanine; Epidermis; Humans; Melanocytes; | 1979 |
The urinary melanogen cysteinyldopa in melanoma and in suntanning: Australian experience.
Topics: Adolescent; Adult; Australia; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Melanoma; Neoplasm Meta | 1978 |
Adaptation of Sinclair swine melanoma cells to long-term growth in vitro.
Topics: Animals; Cell Division; Cell Line; Dihydroxyphenylalanine; Female; Male; Melanoma; Neoplasm Regressi | 1979 |
Human malignant melanoma. Melanosomal polymorphism and the ultrastructural dopa reaction.
Topics: Dihydroxyphenylalanine; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Humans; Melanocy | 1978 |
Simple screening test for estimation of some phenolic and indolic compounds in urine application to melanoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Indoles; M | 1978 |
[Melanoma metabolites (proceedings)].
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1978 |
Involvement of tyrosinase in melanin formation in murine melanoma.
Topics: Animals; Catechol Oxidase; Cell Line; Chelating Agents; Chromatography, DEAE-Cellulose; Dihydroxyphe | 1975 |
Cells with positive Dopa--reaction in the infiltrate of basal cell epithelioma (bce).
Topics: Carcinoma, Basal Cell; Catechol Oxidase; Dihydroxyphenylalanine; Eosinophils; Granulocytes; Mast Cel | 1975 |
Melanin-producing cells seen in neurofibromatous lesions of Recklinghausen's disease -- a study with fluorescence method (Falck and Hillarp).
Topics: Adrenergic Fibers; Adult; Cholinergic Fibers; Dihydroxyphenylalanine; Humans; Male; Melanins; Melano | 1976 |
Dopa-positive cells and melanin in basal cell epithelioma (BCE).
Topics: Carcinoma, Basal Cell; Dihydroxyphenylalanine; Histocytochemistry; Humans; Melanins; Melanocytes; Sk | 1976 |
On the occurrence of cysteinyldopa and dopa in melanocytes and benign nevi cells.
Topics: Adolescent; Child; Child, Preschool; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Me | 1976 |
Congenital circumscribed hypomelanosis: a characterization based on electron microscopic study of tuberous sclerosis, nevus depigmentosus, and piebaldism.
Topics: Adolescent; Adult; Albinism; Black People; Child; Child, Preschool; Dihydroxyphenylalanine; Female; | 1975 |
[Urinary 5-S-cysteinyldopa levels in patients with malignant melanoma. Preliminary results].
Topics: Creatinine; Cysteine; Dihydroxyphenylalanine; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1975 |
[Chemical diagnosis of melanoma].
Topics: Cysteine; Dihydroxyphenylalanine; Humans; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1976 |
Differentiation of new metastatic variants of B16 melanoma under different culture conditions.
Topics: Animals; Cell Transformation, Neoplastic; Dihydroxyphenylalanine; Genetic Variation; Lung Neoplasms; | 1992 |
Ultrastructural morphology of hypomelanosis in equine cutaneous papilloma.
Topics: Animals; Dihydroxyphenylalanine; Horse Diseases; Horses; Melanins; Melanocytes; Microscopy, Electron | 1990 |
[Biochemical diagnoses of malignant melanomas with determinations of 5-S-cysteinyldopa in lesions].
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cysteinyldopa; Dihydroxyphenylalanine; Female; Hu | 1989 |
[Definitive diagnosis of early malignant melanoma lesions by the quantitative analysis of 5-S-cysteinyldopa in the tissue and touch fluorescence method].
Topics: Adolescent; Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Fluorescence; Humans; Male; | 1989 |
[Multiple generalized glomus tumors. Morphologic and biochemical findings].
Topics: Cyclic AMP; Dihydroxyphenylalanine; Female; Glomus Tumor; Hemangioma, Cavernous; Humans; Middle Aged | 1986 |
[Comparative studies between excretion of 5-S-cysteinyldopa and indole melanogens in urine].
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Indoles; Melanoma; Skin Neoplasms | 1986 |
A study of melanocytes in the normal skin surrounding malignant melanomata.
Topics: Adult; Aged; Cell Count; Chromatophores; Dihydroxyphenylalanine; Female; Humans; Male; Melanins; Mel | 1970 |
Tyrosinase activity in dermal nevus cells.
Topics: Catechol Oxidase; Dihydroxyphenylalanine; Endoplasmic Reticulum; Histocytochemistry; Humans; Melanin | 1971 |
Dopa and 5-S-cysteinyldopa in malignant melanoma in Ugandan Africans.
Topics: Adult; Aged; Black People; Cysteine; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Middle | 1974 |
5-S-cysteinyldopa in melanomas of Caucasians.
Topics: Adult; Aged; Chromatography; Cysteine; Dihydroxyphenylalanine; Female; Fluorometry; Hair; Humans; Me | 1974 |
Electron microscopic studies on transplantable melanotic and amelanotic melanomas in hamsters.
Topics: Animals; Catechol Oxidase; Chromatophores; Cricetinae; Cytoplasm; Cytoplasmic Granules; Dihydroxyphe | 1973 |
[The morphogenesis and histological classification of nevocellular nevuses].
Topics: Adult; Catechol Oxidase; Dihydroxyphenylalanine; Histocytochemistry; Humans; Lipid Metabolism; Male; | 1973 |
Cellular response of seborrheic keratosis following croton oil irritation and surgical trauma with special reference to melanoacanthoma.
Topics: Aged; Biopsy; Cell Biology; Croton Oil; Dermatitis, Seborrheic; Dihydroxyphenylalanine; Humans; Kera | 1965 |
[Adhesive tape induced depigmentation. An ultrastructural study and comparison with vitiligo and vitiliginous depigmentation associated with melanoma (author's transl)].
Topics: Adhesiveness; Bandages; Basement Membrane; Biopsy; Diagnosis, Differential; Dihydroxyphenylalanine; | 1974 |
Melanocytic neoplasms.
Topics: Dihydroxyphenylalanine; Epinephrine; Humans; Melanins; Melanocytes; Melanoma; Mustard Compounds; Neo | 1974 |
[The combined action of 2,5,6-H3-DOPA and alkylating agents on Harding-Passy melanoma].
Topics: Animals; Cyclophosphamide; Dihydroxyphenylalanine; Melanoma; Melphalan; Mice; Mice, Inbred BALB C; N | 1972 |
Levodopa and malignant melanoma.
Topics: Dihydroxyphenylalanine; Humans; Male; Melanoma; Middle Aged; Parkinson Disease; Skin Neoplasms | 1973 |
Levodopa and melanoma.
Topics: Aged; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Humans; Male; Melanoma; Middle Aged; | 1974 |
Fluorescent dopa reaction of nevi and melanomas.
Topics: Dihydroxyphenylalanine; Fluorescence; Humans; Lymphatic Metastasis; Melanoma; Microscopy, Fluorescen | 1966 |
Generalized melanosis secondary to malignant melanoma. Report of a case with serum and tissue tyrosinase studies.
Topics: Catechol Oxidase; Dihydroxyphenylalanine; Female; Humans; Lung Neoplasms; Melanins; Melanoma; Melano | 1969 |
The melanocyte: its cytochemical and immunological relationship to cells of the endocrine polypeptide (APUD) series.
Topics: Animals; Cholinesterases; Cricetinae; Dihydroxyphenylalanine; Fluorescent Antibody Technique; Gastri | 1969 |
[Immunologic analysis of tyrosinase in malignant melanoma, nevi and clinically normal skin].
Topics: Adolescent; Adult; Agar; Aged; Catechol Oxidase; Child; Child, Preschool; Dihydroxyphenylalanine; El | 1971 |
Tyrosinase isolated from mouse melanoma melanosome.
Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatogr | 1971 |
Melanization and tyrosinase activity.
Topics: Animals; Binding Sites; Catechol Oxidase; Copper; Dihydroxyphenylalanine; Melanins; Melanocytes; Mel | 1971 |
Multiple primary melanoma following administration of levodopa.
Topics: Administration, Oral; Dihydroxyphenylalanine; Humans; Male; Melanoma; Middle Aged; Neoplasm Recurren | 1972 |
Ultrastructural comparison of two human malignant melanoma cell lines.
Topics: Acid Phosphatase; Back; Cell Line; Chromatophores; Clone Cells; Culture Techniques; Dihydroxyphenyla | 1970 |
Degradation of melanosomes by lysosomes.
Topics: Acid Phosphatase; Amino Acids; Animals; Carbon Isotopes; Cathepsins; Culture Techniques; Dihydroxyph | 1971 |