dihydroxyphenylalanine has been researched along with Schizophrenia in 80 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to investigate possible disturbances of the blood-brain transport mechanisms of monoamine precursors in manic-depressive illness and schizophrenia, we have measured the brain arterio-venous difference of DOPA, or 5-HTP, or tyrosine and tryptophan in 36 patients, during the infusion of either L-DOPA or L-5-HTP." | 7.66 | Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia. ( Gaillard, JM; Tissot, R, 1979) |
| "Clozapine is an atypical neuroleptic medication with superior efficacy to conventional antipsychotic agents for patients with chronic, symptomatic schizophrenia." | 5.07 | The effect of clozapine on plasma norepinephrine: relationship to clinical efficacy. ( Breier, A; Buchanan, RW; Goldstein, DS; Holmes, C; Listwak, S; Waltrip, RW, 1994) |
| "In order to investigate possible disturbances of the blood-brain transport mechanisms of monoamine precursors in manic-depressive illness and schizophrenia, we have measured the brain arterio-venous difference of DOPA, or 5-HTP, or tyrosine and tryptophan in 36 patients, during the infusion of either L-DOPA or L-5-HTP." | 3.66 | Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia. ( Gaillard, JM; Tissot, R, 1979) |
| "Twelve patients with treatment-resistant schizophrenia, twelve patients with schizophrenia who had responded to antipsychotics, and twelve healthy volunteers matched for gender, age, ethnicity, weight, and cigarette smoking underwent [(18)F]-DOPA PET scanning." | 1.38 | Dopamine synthesis capacity in patients with treatment-resistant schizophrenia. ( Demjaha, A; Howes, OD; Kapur, S; McGuire, PK; Murray, RM, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (70.00) | 18.7374 |
| 1990's | 5 (6.25) | 18.2507 |
| 2000's | 7 (8.75) | 29.6817 |
| 2010's | 10 (12.50) | 24.3611 |
| 2020's | 2 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Sabaroedin, K | 1 |
| Razi, A | 1 |
| Chopra, S | 1 |
| Tran, N | 2 |
| Pozaruk, A | 1 |
| Chen, Z | 1 |
| Finlay, A | 1 |
| Nelson, B | 1 |
| Allott, K | 1 |
| Alvarez-Jimenez, M | 1 |
| Graham, J | 1 |
| Yuen, HP | 1 |
| Harrigan, S | 1 |
| Cropley, V | 1 |
| Sharma, S | 1 |
| Saluja, B | 1 |
| Williams, R | 1 |
| Pantelis, C | 1 |
| Wood, SJ | 1 |
| O'Donoghue, B | 1 |
| Francey, S | 1 |
| McGorry, P | 1 |
| Aquino, K | 1 |
| Fornito, A | 1 |
| Avram, M | 1 |
| Brandl, F | 1 |
| Knolle, F | 1 |
| Cabello, J | 1 |
| Leucht, C | 1 |
| Scherr, M | 1 |
| Mustafa, M | 1 |
| Koutsouleris, N | 1 |
| Leucht, S | 1 |
| Ziegler, S | 1 |
| Sorg, C | 1 |
| Eisenberg, DP | 1 |
| Yankowitz, L | 1 |
| Ianni, AM | 1 |
| Rubinstein, DY | 1 |
| Kohn, PD | 2 |
| Hegarty, CE | 1 |
| Gregory, MD | 1 |
| Apud, JA | 1 |
| Berman, KF | 2 |
| Jauhar, S | 3 |
| Nour, MM | 1 |
| Veronese, M | 4 |
| Rogdaki, M | 2 |
| Bonoldi, I | 3 |
| Azis, M | 1 |
| Turkheimer, F | 2 |
| McGuire, P | 1 |
| Young, AH | 1 |
| Howes, OD | 9 |
| Dahoun, T | 2 |
| Pardiñas, AF | 2 |
| Bloomfield, MAP | 2 |
| Froudist-Walsh, S | 2 |
| Nosarti, C | 1 |
| Korth, C | 1 |
| Hennah, W | 1 |
| Walters, J | 1 |
| Prata, D | 1 |
| D'Ambrosio, E | 1 |
| Walters, JTR | 1 |
| Demjaha, A | 2 |
| Egerton, A | 2 |
| Murray, RM | 3 |
| Kapur, S | 2 |
| Stone, JM | 1 |
| McGuire, PK | 5 |
| Williams, M | 1 |
| Ibrahim, K | 1 |
| Leung, G | 1 |
| Kim, E | 1 |
| Beck, K | 1 |
| Seo, S | 1 |
| Park, JW | 1 |
| Lee, JS | 1 |
| Lee, YS | 1 |
| Kwon, JS | 1 |
| Montgomery, AJ | 1 |
| Asselin, MC | 2 |
| Valli, I | 2 |
| Tabraham, P | 1 |
| Bramon-Bosch, E | 1 |
| Valmaggia, L | 1 |
| Johns, L | 1 |
| Broome, M | 2 |
| Grasby, PM | 2 |
| Fusar-Poli, P | 1 |
| Allen, P | 1 |
| Booij, J | 1 |
| van Amelsvoort, T | 1 |
| TAKESADA, M | 1 |
| KAKIMOTO, Y | 1 |
| SANO, I | 1 |
| KANEKO, Z | 1 |
| SAINTJEAN, A | 1 |
| DONALD, MW | 1 |
| BAN, TA | 1 |
| KUEHL, FA | 2 |
| HICHENS, M | 1 |
| ORMOND, RE | 2 |
| MEISINGER, MA | 2 |
| GALE, PH | 1 |
| CIRILLO, VJ | 2 |
| BRINK, NG | 2 |
| TURNER, WJ | 1 |
| MERLIS, S | 5 |
| LENZ, H | 1 |
| Schönfeldt-Lecuona, C | 1 |
| Juengling, FD | 1 |
| Connemann, BJ | 1 |
| Reske, SN | 1 |
| Spitzer, M | 1 |
| Kassubek, J | 1 |
| McGowan, S | 1 |
| Lawrence, AD | 1 |
| Sales, T | 1 |
| Quested, D | 1 |
| Grasby, P | 1 |
| Kumakura, Y | 1 |
| Cumming, P | 2 |
| Vernaleken, I | 1 |
| Buchholz, HG | 1 |
| Siessmeier, T | 1 |
| Heinz, A | 1 |
| Kienast, T | 1 |
| Bartenstein, P | 1 |
| Gründer, G | 1 |
| Huttunen, J | 1 |
| Heinimaa, M | 1 |
| Svirskis, T | 1 |
| Nyman, M | 1 |
| Kajander, J | 1 |
| Forsback, S | 1 |
| Solin, O | 3 |
| Ilonen, T | 1 |
| Korkeila, J | 1 |
| Ristkari, T | 1 |
| McGlashan, T | 1 |
| Salokangas, RK | 2 |
| Hietala, J | 3 |
| Krupenina, LB | 1 |
| Vinogradov, MV | 1 |
| Tegeler, J | 1 |
| Wöller, W | 1 |
| Misionzhnik, EIu | 1 |
| Vertogradova, OP | 1 |
| Krasnov, VN | 1 |
| Salenko, BB | 1 |
| Anokhina, IP | 1 |
| Kogan, BM | 1 |
| Young, SN | 1 |
| Gauthier, S | 1 |
| Chouinard, G | 2 |
| Anderson, GM | 1 |
| Purdy, WC | 1 |
| Syvälahti, E | 2 |
| Vuorio, K | 2 |
| Räkköläinen, V | 2 |
| Bergman, J | 2 |
| Haaparanta, M | 2 |
| Kuoppamäki, M | 2 |
| Kirvelä, O | 1 |
| Ruotsalainen, U | 2 |
| Reith, J | 1 |
| Benkelfat, C | 1 |
| Sherwin, A | 1 |
| Yasuhara, Y | 1 |
| Kuwabara, H | 1 |
| Andermann, F | 1 |
| Bachneff, S | 1 |
| Diksic, M | 1 |
| Dyve, SE | 1 |
| Etienne, P | 1 |
| Evans, AC | 1 |
| Lal, S | 1 |
| Shevell, M | 1 |
| Savard, G | 1 |
| Wong, DF | 1 |
| Gjedde, A | 1 |
| Breier, A | 2 |
| Buchanan, RW | 1 |
| Waltrip, RW | 1 |
| Listwak, S | 1 |
| Holmes, C | 1 |
| Goldstein, DS | 2 |
| Elman, I | 1 |
| Eisenhofer, G | 1 |
| Folio, J | 1 |
| Malhotra, AK | 1 |
| Adler, CM | 1 |
| Pickar, D | 1 |
| Vilkman, H | 1 |
| Eronen, E | 1 |
| Elkashef, AM | 1 |
| Doudet, D | 1 |
| Bryant, T | 1 |
| Cohen, RM | 1 |
| Li, SH | 1 |
| Wyatt, RJ | 1 |
| Meyer-Lindenberg, A | 1 |
| Miletich, RS | 1 |
| Esposito, G | 1 |
| Carson, RE | 1 |
| Quarantelli, M | 1 |
| Weinberger, DR | 1 |
| Carlsson, A | 2 |
| Mileikovskii, IuA | 1 |
| Gaillard, JM | 1 |
| Tissot, R | 2 |
| Mato, M | 1 |
| Uchiyama, Y | 1 |
| Kurihara, K | 1 |
| Karasawa, T | 1 |
| Levin, SL | 1 |
| Beaton, JM | 1 |
| Fleming, P | 1 |
| Makar, H | 1 |
| Hunter, KR | 1 |
| Hegedus, ZL | 1 |
| Altschule, MD | 1 |
| Nayak, U | 1 |
| Roberts, E | 1 |
| Keegan, DL | 1 |
| Rajput, AH | 1 |
| Lipton, MA | 1 |
| Matthysse, S | 1 |
| Stevens, J | 1 |
| Wilson, K | 1 |
| Foote, W | 1 |
| Barchas, JD | 1 |
| Ciaranello, RD | 1 |
| Dominic, JA | 1 |
| Deguchi, T | 1 |
| Orenberg, EK | 1 |
| Renson, J | 1 |
| Kessler, S | 1 |
| Crawford, JP | 1 |
| Kanig, K | 1 |
| Oesterle, W | 1 |
| Klawans, HL | 1 |
| Goetz, C | 1 |
| Westheimer, R | 1 |
| Bryson, G | 1 |
| Snyder, SH | 1 |
| Angrist, B | 2 |
| Sathananthan, G | 3 |
| Wilk, S | 1 |
| Gershon, S | 3 |
| Horvath, TB | 1 |
| Meares, RA | 1 |
| Israelstam, DM | 1 |
| Yaryura-Tobias, JA | 3 |
| Diamond, B | 2 |
| Stancer, HC | 1 |
| Angrist, BM | 1 |
| Mathieu, P | 1 |
| Charvet, JC | 1 |
| Chazot, G | 1 |
| Trouillas, P | 1 |
| Inanaga, K | 2 |
| Inoue, K | 1 |
| Tachibana, H | 2 |
| Oshima, M | 2 |
| Kotorii, T | 1 |
| Hökfelt, T | 1 |
| Ljungdahl, A | 1 |
| Fuxe, K | 1 |
| Johansson, O | 1 |
| Rysánek, K | 1 |
| Matussek, N | 1 |
| Tran-Manh, N | 1 |
| Laplante, M | 2 |
| Saint-Laurent, J | 1 |
| LeBel, E | 2 |
| Kimura, N | 1 |
| Tsukue, I | 1 |
| Nakamura, K | 1 |
| Koketsu, K | 1 |
| Persson, T | 1 |
| Roos, BE | 1 |
| Bruno, A | 2 |
| Bruno, SC | 1 |
| Wolpert, A | 1 |
| Dana, L | 1 |
| Bunney, WE | 1 |
| Tobias, JA | 1 |
| Allegranza, A | 1 |
| Wagner, AF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Controlled Double Blind Crossover Study of the Effect of a Single Dose of N-acetylcysteine Versus Placebo on Brain Glutamate in Patients With Psychotic Disorders[NCT02483130] | 20 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis[NCT05282277] | Phase 4 | 103 participants (Anticipated) | Interventional | 2022-04-20 | Recruiting | ||
| Inpatient Evaluation of Neuropsychiatric Patients[NCT00001247] | 700 participants (Anticipated) | Observational | 1989-09-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for dihydroxyphenylalanine and Schizophrenia
| Article | Year |
|---|---|
Imaging as tool to investigate psychoses and antipsychotics.
Topics: Antipsychotic Agents; Diagnostic Imaging; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane | 2012 |
The common pathophysiology of monaminergic psychoses: a new hypothesis.
Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrie | 1975 |
Methylation & schizophrenia.
Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihyd | 1975 |
Implications of catecholamine systems of the brain in schizophrenia.
Topics: Amphetamine; Brain; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Histamine H1 A | 1974 |
[Biochemical treatment possibilities in psychoses].
Topics: Amino Acids; Ascorbic Acid; Dihydroxyphenylalanine; Humans; Methionine; Niacinamide; Nicotinic Acids | 1969 |
Pathophysiology of schizophrenia and the striatum.
Topics: Adult; Amphetamine; Animals; Basal Ganglia; Catalepsy; Caudate Nucleus; Dihydroxyphenylalanine; Dopa | 1972 |
Catecholamines in the brain as mediators of amphetamine psychosis.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain Chemistry; Bromides; Catecholamines; Cats; Cocain | 1972 |
Psychopharmacology. Yesterday, today and tomorrow: a point of view.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Canada; Carbonates; Depression; Dihydroxyp | 1973 |
[Relation of monoamines to mental disorders].
Topics: Amines; Animals; Bipolar Disorder; Catecholamines; Central Nervous System; Depression; Dihydroxyphen | 1970 |
9 trials available for dihydroxyphenylalanine and Schizophrenia
| Article | Year |
|---|---|
The effect of clozapine on plasma norepinephrine: relationship to clinical efficacy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Adult; Analysis of Variance; Clozapine; | 1994 |
Mechanism of peripheral noradrenergic stimulation by clozapine.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Catechols; Clozapine; Dihydroxyphenylalanine; Fem | 1999 |
Levodopa in drug-induced extrapyramidal disorders.
Topics: Dihydroxyphenylalanine; Extrapyramidal Tracts; Fluphenazine; Humans; Movement Disorders; Orphenadrin | 1970 |
Psychiatric manifestations of levodopa.
Topics: Adult; Affect; Clinical Trials as Topic; Depression; Dihydroxyphenylalanine; Evaluation Studies as T | 1972 |
Behavioral effects of L-dopa in schizophrenic patients.
Topics: Adult; Analysis of Variance; Behavior; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Hum | 1973 |
Response threshold to levodopa in psychiatric patients.
Topics: Adult; Brain Chemistry; Clinical Trials as Topic; Cognition Disorders; Dihydroxyphenylalanine; Dopam | 1973 |
Clinical and animal experiments concerning the function of brain catecholamines.
Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Ca | 1971 |
The action of L-dopa on schizophrenic patients (a preliminary report).
Topics: Adult; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Male; Middle Aged; Placebos; Schizo | 1970 |
Effects of L-DOPA on pharmacological parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Haloper | 1966 |
62 other studies available for dihydroxyphenylalanine and Schizophrenia
| Article | Year |
|---|---|
Frontostriatothalamic effective connectivity and dopaminergic function in the psychosis continuum.
Topics: Dihydroxyphenylalanine; Dopamine; Humans; Magnetic Resonance Imaging; Neural Pathways; Psychotic Dis | 2023 |
Aberrant striatal dopamine links topographically with cortico-thalamic dysconnectivity in schizophrenia.
Topics: Adult; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Humans; Magnetic | 2020 |
Presynaptic Dopamine Synthesis Capacity in Schizophrenia and Striatal Blood Flow Change During Antipsychotic Treatment and Medication-Free Conditions.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Do | 2017 |
A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Dihydroxyphenylalanine; Dopa | 2017 |
The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study.
Topics: Adult; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Genetic Predisposition to Disease; | 2018 |
The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study.
Topics: Adult; Chromosomes, Human, Pair 10; Corpus Striatum; Cytoskeletal Proteins; Dihydroxyphenylalanine; | 2019 |
Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function.
Topics: Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Dihydroxyphenylalanine; Dopamine; Female; | 2014 |
Midbrain dopamine function in schizophrenia and depression: a post-mortem and positron emission tomographic imaging study.
Topics: Adult; Depressive Disorder, Major; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Humans | 2013 |
Presynaptic Dopamine Capacity in Patients with Treatment-Resistant Schizophrenia Taking Clozapine: An [
Topics: Antipsychotic Agents; Biomarkers; Clozapine; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; | 2017 |
Elevated striatal dopamine function linked to prodromal signs of schizophrenia.
Topics: Adult; Brain Mapping; Cognition Disorders; Corpus Striatum; Diagnostic and Statistical Manual of Men | 2009 |
Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study.
Topics: Adult; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Functional Laterality; Human | 2010 |
Dopamine synthesis capacity in patients with treatment-resistant schizophrenia.
Topics: Adult; Antipsychotic Agents; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Drug Resistance; Fem | 2012 |
3,4-DIMETHOXYPHENYLETHYLAMINE AND OTHER AMINES IN THE URINE OF SCHIZOPHRENIC PATIENTS.
Topics: Amines; Chlorpromazine; Chromatography; Dihydroxyphenylalanine; Dimethoxyphenylethylamine; Dopamine; | 1963 |
[THE PSYCHOPHYSIOLOGICAL EFFECTS OF METHYLDOPA].
Topics: Blood Pressure; Blood Pressure Determination; Depression; Depressive Disorder; Dihydroxyphenylalanin | 1963 |
PARA-O-METHYLATION OF DOPAMINE IN SCHIZOPHRENIC AND NORMAL INDIVIDUALS.
Topics: Chromatography; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Metabolism; Methylation; Nore | 1964 |
A CLINICAL TRIAL OF PARGYLINE AND DOPA IN PSYCHOTIC SUBJECTS.
Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Depression; Depressive Disorder, Majo | 1964 |
[Paper chromatographic studies on the urine of schizophrenics and healthy subjects before and after DOPA administration].
Topics: Chromatography; Chromatography, Paper; Dihydroxyphenylalanine; Healthy Volunteers; Humans; Schizophr | 1962 |
Complete dopamine D2 receptor occupancy without extrapyramidal side effects under benperidol.
Topics: Adult; Basal Ganglia; Benperidol; Carbon Radioisotopes; Clozapine; Dihydroxyphenylalanine; Dyskinesi | 2004 |
Presynaptic dopaminergic dysfunction in schizophrenia: a positron emission tomographic [18F]fluorodopa study.
Topics: Adult; Case-Control Studies; Cognition; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; M | 2004 |
Elevated [18F]fluorodopamine turnover in brain of patients with schizophrenia: an [18F]fluorodopa/positron emission tomography study.
Topics: Adult; Brain; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Male; Positron-Emission Tomogr | 2007 |
Striatal dopamine synthesis in first-degree relatives of patients with schizophrenia.
Topics: Adult; Analysis of Variance; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Rad | 2008 |
[State of the adrenergic and cholinergic systems of schizophrenic patients during the process of psychopharmacotherapy].
Topics: Acetylcholine; Acetylcholinesterase; Adult; Antipsychotic Agents; Catecholamines; Dihydroxyphenylala | 1980 |
[Therapeutic measures in tardive dyskinesia].
Topics: Age Factors; Amantadine; Antipsychotic Agents; Baclofen; Benzodiazepines; Bromocriptine; Deanol; Dih | 1983 |
[Changes in the levels of adrenergic and serotoninergic indices in patients with depressive states].
Topics: Adolescent; Adult; Biogenic Amines; Depression; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homov | 1981 |
[Various features of dopamine metabolism in schizophrenia].
Topics: Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Humans; Norepinephrine; Schizophre | 1981 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; | 1982 |
Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients.
Topics: Adult; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Ma | 1995 |
Elevated dopa decarboxylase activity in living brain of patients with psychosis.
Topics: Adult; Animals; Brain; Dihydroxyphenylalanine; Dopa Decarboxylase; Epilepsy, Complex Partial; Female | 1994 |
Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia.
Topics: Adolescent; Adult; Corpus Striatum; Depressive Disorder; Dihydroxyphenylalanine; Dopamine; Female; F | 1999 |
6-(18)F-DOPA PET study in patients with schizophrenia. Positron emission tomography.
Topics: Adult; Antipsychotic Agents; Aromatic-L-Amino-Acid Decarboxylases; Brain; Case-Control Studies; Chro | 2000 |
Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia.
Topics: Cerebrovascular Circulation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotop | 2002 |
[Cerebral amines].
Topics: Amines; Animals; Brain; Dihydroxyphenylalanine; Haplorhini; Humans; Mental Disorders; Mice; Neurons; | 1976 |
Does dopamine play a role in schizophrenia?
Topics: 5-Hydroxytryptophan; Acetylcholine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Brain; | 1977 |
[Excretion of catecholamines and tryptophan derivatives in schizophrenia].
Topics: Adolescent; Adult; Biogenic Amines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Humans; H | 1976 |
Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia.
Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Humans; Middle Aged; Sc | 1979 |
Fluorescent substance in leukocytes and platelets of psychiatric patients.
Topics: Bipolar Disorder; Blood Platelets; Depression; Dihydroxyphenylalanine; Dopamine; Histocytochemistry; | 1977 |
[Stein and Wise's neurochemical model of schizophrenia].
Topics: Biogenic Amines; Brain; Brain Mapping; Catechol O-Methyltransferase; Chemical Phenomena; Chemistry; | 1977 |
Studies on rheomelanins. 3. Excessive hemolysis associated with the production of rheomelanins from L-norepinephrine, from dopamine and from L-dopa in the blood of chronic schizophrenic patients.
Topics: Chromatography, Paper; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Erythrocytes; Hemolysis; H | 1971 |
Contributions of neurochemistry to neurology and psychiatry. Introduction.
Topics: Aminobutyrates; Basal Ganglia; Brain; Dihydroxyphenylalanine; Humans; Neural Inhibition; Neurotransm | 1973 |
Drug induced dystonia tarda: treatment with L-dopa.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Diazepam; Dihydroxyphenylalanine; Dystonia Mu | 1973 |
Neuropsychopharmacology of monoamines and their regulatory enzymes.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Biogenic Amines; Brain; Cocaine; Dextroamphe | 1974 |
GABA blockade, dopamine and schizophrenia: experimental studies in the cat.
Topics: Alkaloids; Aminobutyrates; Amitriptyline; Animals; Atropine; Behavior, Animal; Cats; Dextroamphetami | 1974 |
Genetic differences in mechanisms involving neuroregulators.
Topics: Adrenal Medulla; Animals; Brain; Catecholamines; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Dopam | 1974 |
Antipsychotic drugs and catecholamine synapses.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Catecholamines; Chlorprom | 1974 |
Dopa in parkinson's disease.
Topics: Chorea; Dihydroxyphenylalanine; Humans; Parkinson Disease; Schizophrenia | 1969 |
Biogenic amines in normal and abnormal behavioral states.
Topics: Acetylcholine; Aggression; Aminobutyrates; Arousal; Blood-Brain Barrier; Brain; Brain Stem; Catechol | 1971 |
Amphetamine psychosis: behavioral and biochemical aspects.
Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio | 1974 |
The relevance of the neurophysiological concepts of excitation and inhibition to clinical psychiatry.
Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Alcohol Amnestic Disorder; Anxiety; Arousal; Dihydrox | 1973 |
From medical physicist to psychopharmacologist: a neo-renaissance interdisciplinary evolution of.
Topics: Dihydroxyphenylalanine; Disulfiram; Electroconvulsive Therapy; Enzyme Induction; History, 20th Centu | 1972 |
[4-O-Methylated catecholamines: 3-hydroxy, 4-methoxyphenylacetic acid (homo-isovanillic acid, iso-HVA) in biological media: urine, cerebrospinal fluid, and brain tissue].
Topics: Animals; Azo Compounds; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; Chromatography, Paper; Di | 1972 |
Effect of L-dopa in schizophrenia.
Topics: Adult; Affective Symptoms; Behavior; Cognition Disorders; Communication; Delusions; Depersonalizatio | 1972 |
Dopamine nerve terminals in the rat limbic cortex: aspects of the dopamine hypothesis of schizophrenia.
Topics: Animals; Carbidopa; Dihydroxyphenylalanine; Disulfides; Dopamine; Dopamine beta-Hydroxylase; Humans; | 1974 |
Abnormalities in 14 CO 2 production from DL-3,4-dihydroxyphenylalanine-carboxyl- 14 C in schizophrenia and parkinsonism: a preliminary report.
Topics: Carbon Dioxide; Carbon Isotopes; Cells, Cultured; Cognition Disorders; Decarboxylation; Dihydroxyphe | 1972 |
L-DOPA therapy in drug-induced parkinsonism evaluated by the method measuring the facial expression.
Topics: Adult; Dihydroxyphenylalanine; Facial Expression; Female; Humans; Male; Movement; Parkinson Disease; | 1971 |
Three cases of schizophrenia treated with L-dopa.
Topics: Adult; Autistic Disorder; Delusions; Dihydroxyphenylalanine; Drug Synergism; Female; Hallucinations; | 1971 |
Clinical and pharmacological effects of monoamine precursors or haloperidol in chronic schizophrenia.
Topics: 5-Hydroxytryptophan; Dihydroxyphenylalanine; Haloperidol; Humans; Hydroxyindoleacetic Acid; Phenylac | 1968 |
Action of L-Dopa in drug induced extrapyramidalism.
Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human | 1970 |
Present status of psychological reactions to L-DOPA.
Topics: Behavior; Depression; Dihydroxyphenylalanine; Humans; Parkinson Disease; Schizophrenia | 1970 |
Levodopa and schizophrenia.
Topics: Brain; Dihydroxyphenylalanine; Humans; Parkinson Disease; Psychoses, Substance-Induced; Schizophreni | 1970 |
Decarboxylation of radioactive DOPA by erythrocytes in schizophrenia.
Topics: Carbon Dioxide; Carbon Isotopes; Chemistry, Organic; Decarboxylation; Dihydroxyphenylalanine; Erythr | 1971 |
The effect of haloperidol on the urinary excretion of dopamine, homovanillic and vanilmandelic acids in schizophrenics.
Topics: Adolescent; Adult; Dihydroxyphenylalanine; Dopamine; Haloperidol; Humans; Male; Mandelic Acids; Phen | 1965 |
A further study of catecholamine omicron-methylation in schizophrenia.
Topics: Adult; Aged; Brain Chemistry; Catecholamines; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Fe | 1966 |