dihydroxyphenylalanine has been researched along with Pain in 25 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dopamine-deficient mice have a rightward shift in the dose-response curve to morphine on the tail-flick test (a pain sensitivity assay), suggesting either a decreased sensitivity to the analgesic effects of morphine and/or basal hyperalgesia." | 1.33 | Morphine reward in dopamine-deficient mice. ( Hnasko, TS; Palmiter, RD; Sotak, BN, 2005) |
| "Reserpine pretreatment antagonized the antinociceptive effect of morphine; this effect was reversed by intraventricular injection of 5-HT." | 1.25 | Antinociceptive activity of morphine after injection of biogenic amines in the cerebral ventricles of the conscious rat. ( Sparkes, CG; Spencer, PS, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (84.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TSOU, K | 1 |
| TU, ZH | 1 |
| KAWAMURA, T | 1 |
| NISHIYAMA, S | 1 |
| IKEDA, S | 1 |
| TAJIMA, K | 1 |
| Prieto, M | 1 |
| Gómez, FM | 1 |
| Teresa Giralt, M | 1 |
| Hnasko, TS | 1 |
| Sotak, BN | 1 |
| Palmiter, RD | 1 |
| Kvetnanský, R | 1 |
| Pacák, K | 1 |
| Sabban, EL | 1 |
| Kopin, IJ | 1 |
| Goldstein, DS | 1 |
| Jääskeläinen, SK | 1 |
| Rinne, JO | 1 |
| Forssell, H | 1 |
| Tenovuo, O | 1 |
| Kaasinen, V | 1 |
| Sonninen, P | 1 |
| Bergman, J | 1 |
| Harvey, JA | 1 |
| Schlosberg, AJ | 1 |
| Yunger, LM | 1 |
| Strelkova, NI | 1 |
| Shchepina, TP | 1 |
| Tsai, CF | 1 |
| Lin, MT | 1 |
| Minton, JP | 3 |
| Dickey, RP | 2 |
| Solov'ev, GM | 1 |
| Matlina, ESh | 1 |
| Contreras, E | 1 |
| Quijada, L | 1 |
| Tamayo, L | 1 |
| Guilleminault, C | 2 |
| Sigwald, J | 1 |
| Castaigne, P | 1 |
| Battista, AF | 1 |
| Wolff, BB | 1 |
| Schneider, KW | 1 |
| Lhermitte, F | 1 |
| Chain, F | 1 |
| Escourolle, R | 1 |
| Chedru, F | 1 |
| Francoual, M | 1 |
| Delwaide, PJ | 1 |
| Schwab, RS | 1 |
| Young, RR | 1 |
| Atarashi, J | 1 |
| Terashi, A | 1 |
| Guggenheim, MA | 1 |
| Couch, JR | 1 |
| Weinberg, W | 1 |
| Sparkes, CG | 1 |
| Spencer, PS | 1 |
| Satoyashi, E | 1 |
| Narabayashi, H | 1 |
| Tsubaki, T | 1 |
| Mozai, T | 1 |
| Sobue, I | 1 |
| Klawans, HL | 1 |
| Garvin, JS | 1 |
| Okinaka, S | 1 |
| Toyokura, Y | 1 |
| Yokoi, S | 1 |
| Shimizu, T | 1 |
| Kono, R | 1 |
3 reviews available for dihydroxyphenylalanine and Pain
| Article | Year |
|---|---|
Behavioral correlates of serotonin depletion.
Topics: 5-Hydroxytryptophan; Acetylcholine; Amygdala; Animals; Behavior, Animal; Brain; Dihydroxyphenylalani | 1975 |
[Cardiac catecholamines in stress situations].
Topics: Adrenal Glands; Animals; Brain Injuries; Burns; Catecholamines; Cold Temperature; Dihydroxyphenylala | 1973 |
[Recent progress in neurology].
Topics: Abdomen; Brain Death; Cerebrovascular Disorders; Demyelinating Diseases; Diffuse Cerebral Sclerosis | 1971 |
22 other studies available for dihydroxyphenylalanine and Pain
| Article | Year |
|---|---|
[EFFECTS OF RESERPINE, ALPHA-METHYL-DOPA AND THEIR INTERACTIONS ON MORPHINE ANALGESIA].
Topics: Analgesia; Animals; Antihypertensive Agents; Catecholamines; Dihydroxyphenylalanine; Electricity; Ho | 1963 |
THE HUMAN HAARSCHEIBE, ITS STRUCTURE AND FUNCTION.
Topics: Alkaline Phosphatase; Capillaries; Cholinesterases; Coloring Agents; Dihydroxyphenylalanine; Hair; H | 1964 |
Effects of acute, repeated and chronic variable stress on in vivo tyrosine hydroxylase activity and on alpha(2)-adrenoceptor sensitivity in the rat brain.
Topics: Acute Disease; Adrenergic alpha-Agonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Bra | 2003 |
Morphine reward in dopamine-deficient mice.
Topics: Analgesics, Opioid; Animals; Brain; Caffeine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relati | 2005 |
Stressor specificity of peripheral catecholaminergic activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Cold Temperature; Dihydroxyphenylalanine; E | 1998 |
Role of the dopaminergic system in chronic pain -- a fluorodopa-PET study.
Topics: Adult; Aged; Burning Mouth Syndrome; Chronic Disease; Dihydroxyphenylalanine; Female; Humans; Middle | 2001 |
[Humeroscapular periarthritis in patients with cervical osteochondrosis].
Topics: Autonomic Nervous System; Brachial Plexus Neuritis; Cervical Vertebrae; Contracture; Dihydroxyphenyl | 1978 |
Pain sensitivity, thermal capability, and brain monoamine turnover in hypertensive rats.
Topics: 5-Hydroxytryptophan; Amines; Animals; Body Temperature Regulation; Brain; Dihydroxyphenylalanine; Hy | 1987 |
Prolactin, F.S.H., and L.H. in breast cancer: effect of levodopa and oophorectomy.
Topics: Adult; Bone Neoplasms; Breast Neoplasms; Dihydroxyphenylalanine; Female; Follicle Stimulating Hormon | 1972 |
Prolactin and human breast cancer.
Topics: Antipsychotic Agents; Bone Neoplasms; Breast Neoplasms; Castration; Dihydroxyphenylalanine; Estrogen | 1974 |
A comparative study of the effects of reserpine and p-chlorophenylalanine on morphine analgesia in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Dihydroxyphenylalanine; Drug Synergism; Fenclonine; Male; M | 1973 |
Sleep studies and therepeutic trial with L-dopa in a case of Stiffman syndrome.
Topics: Benzodiazepinones; Chlorobenzenes; Diazepam; Dihydroxyphenylalanine; Electrocardiography; Electromyo | 1973 |
Levodopa and induced-pain response. A study of patients with Parkinsonian and pain syndromes.
Topics: Aged; Cold Temperature; Dihydroxyphenylalanine; Electric Stimulation; Female; Hot Temperature; Human | 1973 |
[Etiology and therapy of the parotid gland syndrome].
Topics: Antihypertensive Agents; Chewing Gum; Clonidine; Dihydroxyphenylalanine; Eating; Humans; Neostigmine | 1973 |
[A further case of tetanus-like contracture distinct from the stiff man syndrome. Pharmacological and neuropathological study of a case of predominantly spinal encephalomyelitis].
Topics: Aged; Carbamazepine; Contracture; Diazepam; Dihydroxyphenylalanine; Electromyography; Encephalomyeli | 1973 |
Polysynaptic spinal reflexes in Parkinson's disease.
Topics: Aged; Amantadine; Dihydroxyphenylalanine; Drug Combinations; Electromyography; Female; Humans; Male; | 1974 |
Levodopa relief of bone pain from breast cancer.
Topics: Adult; Bone Neoplasms; Breast Neoplasms; Dihydroxyphenylalanine; Female; Humans; Neoplasm Metastasis | 1972 |
Motor dysfunction as a permanent complication of methanol ingestion. Presentation of a case with a beneficial response to levodopa treatment.
Topics: Adolescent; Dihydroxyphenylalanine; Female; Humans; Methanol; Motor Cortex; Movement Disorders; Opti | 1971 |
Antinociceptive activity of morphine after injection of biogenic amines in the cerebral ventricles of the conscious rat.
Topics: Animals; Cerebral Ventricles; Consciousness; Dihydroxyphenylalanine; Dopamine; Injections; Injection | 1971 |
[Round table discussion: topics on neuromuscular disease].
Topics: Abdomen; Dihydroxyphenylalanine; Humans; Myelitis; Myositis; Neuritis; Neuromuscular Diseases; Neuro | 1971 |
Treatment of parkinsonism with L-dopa (study of 105 patients).
Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Anorexia Nervosa; Aspartate Aminotransfe | 1969 |
[Round table conference: current problems of nervos system diseases].
Topics: Abdomen; Behcet Syndrome; Dihydroxyphenylalanine; Encephalitis; Humans; Metabolic Diseases; Myelitis | 1970 |