dihydroxyphenylalanine has been researched along with Nervous System Disorders in 27 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with neurogenic orthostatic hypotension can have deficits in sympathetic neural function at any of several levels of the sympathetic neuraxis." | 1.28 | Patterns of plasma levels of catechols in neurogenic orthostatic hypotension. ( Biaggioni, I; Brown, RT; Garty, M; Goldstein, DS; Kopin, IJ; Polinsky, RJ; Robertson, D; Stull, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (92.59) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GERSTENBRAND, G | 1 |
| PATEISKY, K | 1 |
| Beck, B | 1 |
| Brandt, NJ | 1 |
| Christensen, E | 1 |
| Niederwieser, A | 1 |
| Pedersen, PS | 1 |
| Neu, I | 1 |
| Witt, TN | 1 |
| Autenrieth, W | 1 |
| Snow, BJ | 1 |
| Tooyama, I | 1 |
| McGeer, EG | 1 |
| Yamada, T | 1 |
| Calne, DB | 1 |
| Takahashi, H | 1 |
| Kimura, H | 1 |
| Cumming, P | 1 |
| Gjedde, A | 1 |
| Gehlen, W | 1 |
| Goldstein, DS | 1 |
| Polinsky, RJ | 1 |
| Garty, M | 1 |
| Robertson, D | 1 |
| Brown, RT | 1 |
| Biaggioni, I | 1 |
| Stull, R | 1 |
| Kopin, IJ | 1 |
| Weinmann, RL | 1 |
| Araki, S | 1 |
| Stellar, S | 1 |
| Cooper, IS | 1 |
| Kameyama, M | 1 |
| Matthews, WB | 1 |
| Tsukada, Y | 1 |
| Kuzuya, F | 1 |
| Uono, M | 1 |
| Toyokura, Y | 2 |
| Togi, H | 1 |
| DeQuattro, V | 1 |
| Miura, Y | 1 |
| Booker, HE | 1 |
| Dahl, DS | 1 |
| Kytomaki, O | 1 |
| Nousiainen, R | 1 |
| Pekkarinen, A | 1 |
| Rinne, U | 1 |
| Siirtola, T | 1 |
| Sonninen, V | 1 |
| Viljanen, M | 1 |
| Yahr, MD | 1 |
| Atadzhanov, M | 1 |
| Potvin, AR | 1 |
| Albers, JW | 1 |
| Repa, BS | 1 |
| Henderson, WG | 1 |
| Walker, JE | 1 |
| Stribley, RF | 1 |
| Tourtellotte, WW | 1 |
| Kaliuzhnaia, RA | 1 |
| Käser, H | 1 |
| Mrochek, JE | 1 |
| Dinsmore, SR | 1 |
| Ohrt, DW | 1 |
| Atarashi, J | 1 |
| Terashi, A | 1 |
| Wurtman, RJ | 1 |
| Okinaka, S | 1 |
| Yokoi, S | 1 |
| Shimizu, T | 1 |
| Kono, R | 1 |
| Appenzeller, O | 1 |
| Goss, J | 1 |
| Poskanzer, DC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Quantification of Dopamine Active Transporter (DAT) in Humans: Validation of a New Radiophamaceutical, the [18F] LBT-999[NCT02393027] | Early Phase 1 | 16 participants (Actual) | Interventional | 2015-03-31 | Terminated (stopped due to Enough inclusions for interpretation) | ||
| Norepinephrine Transporter Blockade as a Pathophysiological Biomarker in Neurogenic Orthostatic Hypotension[NCT01316666] | 50 participants (Actual) | Observational | 2011-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for dihydroxyphenylalanine and Nervous System Disorders
| Article | Year |
|---|---|
Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms.
Topics: Animals; Brain; Catechol O-Methyltransferase; Decarboxylation; Dihydroxyphenylalanine; Dopa Decarbox | 1998 |
[Iatrogenic damage possibilities in the drug therapy of neurologic and psychiatric diseases].
Topics: Amantadine; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Central Nervous System Di | 1977 |
[Recent trend in neurology].
Topics: Cerebrovascular Disorders; Demyelinating Diseases; Diet Therapy; Dihydroxyphenylalanine; Epilepsy; H | 1970 |
[Neurology].
Topics: Autonomic Nervous System; Brain Diseases; Cerebrovascular Disorders; Demyelinating Diseases; Dihydro | 1972 |
Advances in neurology.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Anticonvulsants; Antihypertens | 1972 |
L-dopa in neurological disease: current status.
Topics: Aged; Amyotrophic Lateral Sclerosis; Basal Ganglia Diseases; Cerebellar Diseases; Cerebrovascular Di | 1972 |
[Hereditary aspects of Parkinson's disease (review of the literature)].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Diseases in Twins; Female; G | 1973 |
Quantitative evaluation of neuropharmacological trials.
Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin | 1974 |
[Recent progress in neurology].
Topics: Abdomen; Brain Death; Cerebrovascular Disorders; Demyelinating Diseases; Diffuse Cerebral Sclerosis | 1971 |
1 trial available for dihydroxyphenylalanine and Nervous System Disorders
| Article | Year |
|---|---|
Quantitative evaluation of neuropharmacological trials.
Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin | 1974 |
18 other studies available for dihydroxyphenylalanine and Nervous System Disorders
| Article | Year |
|---|---|
[On the effects of I-DOPA on motor disorders in Parkinson's syndrome. An electromyographic study].
Topics: Dihydroxyphenylalanine; Electrocardiography; Humans; Nervous System Diseases; Parkinson Disease | 1962 |
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylala | 1983 |
[Side effects of long-term drug therapy in neurology (author's transl)].
Topics: Adrenal Cortex Hormones; Anticoagulants; Anticonvulsants; Ataxia; Cerebral Hemorrhage; Dihydroxyphen | 1980 |
Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels.
Topics: Adult; Aged; Aged, 80 and over; Autopsy; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioiso | 1993 |
Patterns of plasma levels of catechols in neurogenic orthostatic hypotension.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Catecholamines; Dihydroxyphenylalanine; Humans; Hypotension, | 1989 |
Levodopa therapy in striatonigral degeneration.
Topics: Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Nervous System Diseases; Parkinson Disease | 1972 |
Recent advances in neurosurgical treatment for the elderly.
Topics: Aged; Animals; Brain Neoplasms; Cats; Central Nervous System Diseases; Cerebral Angiography; Cryosur | 1970 |
[Nervous system diseases and metabolism].
Topics: Dihydroxyphenylalanine; Humans; Nervous System Diseases; Parkinson Disease; Peripheral Nervous Syste | 1972 |
Neurogenic factors in human hypertension: mechanism or myth?
Topics: Angiotensin II; Blood Pressure; Catecholamines; Chemical Phenomena; Chemistry; Dihydroxyphenylalanin | 1973 |
Clinical neurology.
Topics: Basal Ganglia; Cerebrovascular Disorders; Coma; Diagnosis, Differential; Dihydroxyphenylalanine; Hum | 1971 |
Effects of L-dopa on plasma growth hormones and insulin.
Topics: Administration, Oral; Amantadine; Blood Glucose; Dihydroxyphenylalanine; Growth Hormone; Humans; Inj | 1972 |
[The syndrome of autonomic vascular dystonia in adolescents and young men with toxic-infectious processes].
Topics: Adolescent; Adult; Autonomic Nervous System; Blood Pressure; Cardiovascular Diseases; Catecholamines | 1972 |
[Biochemical diagnosis of pheochromocytoma, neuroblastoma and other neuro-ectodermal neoplasms].
Topics: Adolescent; Adult; Catecholamines; Child; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Electr | 1972 |
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chroma | 1973 |
Catecholamines and neurologic diseases.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Humans; Nervous System Diseases; Parkinson Disease | 1970 |
[Round table conference: current problems of nervos system diseases].
Topics: Abdomen; Behcet Syndrome; Dihydroxyphenylalanine; Encephalitis; Humans; Metabolic Diseases; Myelitis | 1970 |
Autonomic dysfunction in Parkinson's syndrome.
Topics: Autonomic Nervous System; Body Temperature Regulation; Dihydroxyphenylalanine; Humans; Nervous Syste | 1970 |
L-dopa in Parkinson's syndrome.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Humans; Melanins; Nervous System Diseases; Parkinson | 1969 |