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dihydroxyphenylalanine and Necrosis

dihydroxyphenylalanine has been researched along with Necrosis in 14 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"We assessed the performance of 6-[(18)F]-fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET for differentiating radionecrosis (RN) from tumour progression (PD) in a population of patients with brain metastases, treated with stereotactic radiosurgery."3.81Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery. ( Bozzao, A; Cicone, F; Maurizi Enrici, R; Minniti, G; Papa, A; Romano, A; Scaringi, C; Scopinaro, F; Tavanti, F, 2015)
"We used dopaminergic human neuroblastoma BE(2)-M17 cell lines stably transfected with WT or A30P mutant alpha-synuclein to characterize the effect of alpha-synuclein on dopamine toxicity."3.76Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells. ( Bisaglia, M; Bubacco, L; Cookson, MR; Greggio, E; Maric, D; Miller, DW, 2010)
"These results suggest that hemidystonia is associated with a disturbance of the dopamine system."1.31Putaminal necrosis presenting with hemidystonia. ( Imahori, Y; Kawano, H; Misawa, A; Sawada, T; Takeuchi, Y, 2000)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Lakehayli, Z1
Phlips, P1
Margoum, A1
Saoudi, A1
Hmaid, L1
Nejjar, I1
Oueslati, H1
Bourgois, N1
Dao, S1
Belkhir, F1
Cicone, F2
Carideo, L1
Scaringi, C2
Romano, A2
Mamede, M1
Papa, A2
Tofani, A1
Cascini, GL1
Bozzao, A2
Scopinaro, F2
Minniti, G2
Tavanti, F1
Maurizi Enrici, R1
Bisaglia, M1
Greggio, E1
Maric, D1
Miller, DW1
Cookson, MR1
Bubacco, L1
Rissanen, E1
Paavilainen, T1
Virta, J1
Marttila, RJ1
Rinne, JO1
Airas, L1
Kawano, H1
Takeuchi, Y1
Misawa, A1
Sawada, T1
Imahori, Y1
Miyauchi, Y1
Wieloch, T1
Lindvall, O1
Black, MM2
Wilson-Jones, E1
Laborit, H1
Williams, R1
GorokhovskiÄ­, BI1
Lukicheva, TI1
Osterholm, JL1
Mathews, GJ1
Irvin, JD1
Calesnick, B1
Epstein, WL1
Fukuyama, K1

Reviews

1 review available for dihydroxyphenylalanine and Necrosis

ArticleYear
Problems of fulminant hepatic failure.
    British medical bulletin, 1972, Volume: 28, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Amylases; Brain Diseases; Brain Stem; Diazepam; Dihydroxyphe

1972

Other Studies

13 other studies available for dihydroxyphenylalanine and Necrosis

ArticleYear
What effective technique to differentiate radiation brain necrosis from a tumor progression in patients treated with radiation: A monocentric retrospective study combining the MRI TRAMs technique and the (
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2023, Volume: 27, Issue:4

    Topics: Brain; Brain Neoplasms; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Necrosis; Neopla

2023
Long-term metabolic evolution of brain metastases with suspected radiation necrosis following stereotactic radiosurgery: longitudinal assessment by F-DOPA PET.
    Neuro-oncology, 2021, 06-01, Volume: 23, Issue:6

    Topics: Brain Neoplasms; Dihydroxyphenylalanine; Humans; Necrosis; Positron Emission Tomography Computed Tom

2021
Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery.
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Diagnosis, Differential; Dihydroxyphenylalanine; Fe

2015
Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells.
    BMC neuroscience, 2010, Mar-25, Volume: 11

    Topics: alpha-Synuclein; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Dihydroxyphenylalanine; Dop

2010
Carbon monoxide poisoning-induced nigrostriatal dopaminergic dysfunction detected using positron emission tomography (PET).
    Neurotoxicology, 2010, Volume: 31, Issue:4

    Topics: Adult; Basal Ganglia Diseases; Carbon Monoxide Poisoning; Corpus Striatum; Dihydroxyphenylalanine; D

2010
Putaminal necrosis presenting with hemidystonia.
    Pediatric neurology, 2000, Volume: 22, Issue:3

    Topics: Antiparkinson Agents; Brain Diseases; Child; Dihydroxyphenylalanine; Dose-Response Relationship, Dru

2000
Noradrenaline metabolism in neocortex and hippocampus following transient forebrain ischemia in rats: relation to development of selective neuronal necrosis.
    Journal of neurochemistry, 1989, Volume: 53, Issue:2

    Topics: Animals; Cerebral Cortex; Diencephalon; Dihydroxyphenylalanine; Hippocampus; Ischemic Attack, Transi

1989
The role of the epidermis in the histopathogenesis of lichen planus. Histochemical correlations.
    Archives of dermatology, 1972, Volume: 105, Issue:1

    Topics: Acid Phosphatase; Acute Disease; Biopsy; Catechol Oxidase; Chronic Disease; Depression, Chemical; Di

1972
[Physiopathology and pharmacology of myocardial necrosis].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1974, Volume: 15, Issue:1

    Topics: Animals; Aspartic Acid; Dihydroxyphenylalanine; Glucose; Heart; Humans; Insulin; Lysosomes; Monoamin

1974
[Catecholamine concentration in different parts of the heart following myocardial infarct complicated by cardiac rupture].
    Kardiologiia, 1972, Volume: 12, Issue:11

    Topics: Aged; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Heart Diseases; Humans; Male; Middle Ag

1972
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
    Clinical neurosurgery, 1973, Volume: 20

    Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan

1973
The role of the epidermis in the histopathogenesis of lichen amyloidosus. Histochemical correlations.
    The British journal of dermatology, 1971, Volume: 85, Issue:6

    Topics: Amyloid; Amyloidosis; Biopsy; Catechol Oxidase; Dihydroxyphenylalanine; Esterases; Histocytochemistr

1971
Light and electron microscopic studies of a transplantable melanoma associated with virus-like particles.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Acid Phosphatase; Animals; Cricetinae; Cytoplasmic Granules; Dihydroxyphenylalanine; Endoplasmic Ret

1970