dihydroxyphenylalanine has been researched along with Myoclonic Jerk in 15 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two subjects presented with action tremor around age 10-12 years and developed tremor-dominant parkinsonism with prominent neuropsychiatric features later in their 20s." | 1.72 | WARS2 mutations cause dopa-responsive early-onset parkinsonism and progressive myoclonus ataxia. ( Berutti, R; Bonifati, V; Boumeester, V; Brunet, T; Gdovinova, Z; Han, V; Havrankova, P; Houlden, H; Jech, R; Kaiyrzhanov, R; Kuipers, DJS; Kulcsarova, K; Lackova, A; Mandemakers, W; Orec, L; Ostrozovicova, M; Pavelekova, P; Plecko, B; Rektorova, I; Rizig, M; Skorvanek, M; Steinfeld, R; Tijssen, MAJ; Wagner, M; Winkelmann, J; Zech, M, 2022) |
| "Children with the opsoclonus-myoclonus syndrome (OMS) usually respond to corticotropin (adrenocorticotrophic hormone, ACTH) treatment but the mechanism of benefit is unknown." | 1.30 | Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus. ( Goldstein, DS; Goldstein, EM; Holmes, CS; Huang, YY; Ketner, K; Kinast, M; Lange, BM; Pranzatelli, MR; Sanz, A; Shevell, MI; Stanford, RE; Taff, IP; Tate, E, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Skorvanek, M | 1 |
| Rektorova, I | 1 |
| Mandemakers, W | 1 |
| Wagner, M | 1 |
| Steinfeld, R | 1 |
| Orec, L | 1 |
| Han, V | 1 |
| Pavelekova, P | 1 |
| Lackova, A | 1 |
| Kulcsarova, K | 1 |
| Ostrozovicova, M | 1 |
| Gdovinova, Z | 1 |
| Plecko, B | 1 |
| Brunet, T | 1 |
| Berutti, R | 1 |
| Kuipers, DJS | 1 |
| Boumeester, V | 1 |
| Havrankova, P | 1 |
| Tijssen, MAJ | 1 |
| Kaiyrzhanov, R | 1 |
| Rizig, M | 1 |
| Houlden, H | 1 |
| Winkelmann, J | 1 |
| Bonifati, V | 1 |
| Zech, M | 1 |
| Jech, R | 1 |
| Gasser, T | 1 |
| Pranzatelli, MR | 1 |
| Huang, YY | 1 |
| Tate, E | 1 |
| Goldstein, DS | 1 |
| Holmes, CS | 1 |
| Goldstein, EM | 1 |
| Ketner, K | 1 |
| Kinast, M | 1 |
| Lange, BM | 1 |
| Sanz, A | 1 |
| Shevell, MI | 1 |
| Stanford, RE | 1 |
| Taff, IP | 1 |
| Sawle, GV | 1 |
| Brooks, DJ | 1 |
| Marsden, CD | 1 |
| Frackowiak, RS | 1 |
| Goetz, CG | 1 |
| Klawans, HL | 1 |
| Minoli, G | 1 |
| Tredici, G | 1 |
| Rohmer, F | 1 |
| Warter, JM | 1 |
| Coquillat, G | 1 |
| Maitrot, D | 1 |
| Kurtz, D | 1 |
| Micheletti, G | 1 |
| Mack, G | 1 |
| Mandel, P | 1 |
| Soyka, D | 1 |
| Crawford, JP | 1 |
| Hartmann-von Monakow, K | 1 |
| Bieger, D | 1 |
| Larochelle, L | 1 |
| Hornykiewicz, O | 1 |
| Lhermitte, F | 1 |
| Marteau, R | 1 |
| Degos, CF | 1 |
| Setiey, A | 1 |
| Moene, Y | 1 |
| Chazot, G | 1 |
| Trillet, M | 1 |
| Courjon, J | 1 |
| Narabayashi, H | 1 |
| Roth, JC | 1 |
| Epstein, CJ | 1 |
1 review available for dihydroxyphenylalanine and Myoclonic Jerk
| Article | Year |
|---|---|
Idiopathic, myoclonic and Dopa-responsive dystonia.
Topics: Dihydroxyphenylalanine; Dystonia; Dystonia Musculorum Deformans; Humans; Myoclonus; Phenotype | 1997 |
1 trial available for dihydroxyphenylalanine and Myoclonic Jerk
| Article | Year |
|---|---|
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Di | 1973 |
13 other studies available for dihydroxyphenylalanine and Myoclonic Jerk
| Article | Year |
|---|---|
WARS2 mutations cause dopa-responsive early-onset parkinsonism and progressive myoclonus ataxia.
Topics: Ataxia; Dihydroxyphenylalanine; Humans; Mutation; Myoclonus; Parkinsonian Disorders; Phenotype; Spin | 2022 |
Monoaminergic effects of high-dose corticotropin in corticotropin-responsive pediatric opsoclonus-myoclonus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Catecholamines; Child, Preschool; Dihyd | 1998 |
Corticobasal degeneration. A unique pattern of regional cortical oxygen hypometabolism and striatal fluorodopa uptake demonstrated by positron emission tomography.
Topics: Aged; Animals; Apraxias; Brain Diseases; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; E | 1991 |
Letter: Myoclonus, methysergide, and serotonin.
Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Drug Antagonism; Guinea Pigs; Humans; Methyser | 1974 |
Letter: Levodopa in treatment of myoclonus.
Topics: Dihydroxyphenylalanine; Drug Evaluation; Humans; Myoclonus | 1974 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |
Side-effects of L-dopa in postencephalitic parkinsonism.
Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Myoclonus; Parkinson Disease, Postencep | 1970 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
A model for the quantitative study of central dopaminergic and serotoninergic activity.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine; | 1972 |
[Pharmacologic analysis of a new case of postanoxic intention and action myoclonus].
Topics: Adult; Anesthesia, General; Butyrophenones; Catecholamines; Coma; Dihydroxyphenylalanine; Endoscopy; | 1972 |
[Unusual clinical and electroencephalographic aspects induced by lithium-dopa association].
Topics: Aged; Brain; Cognition Disorders; Coma; Dihydroxyphenylalanine; Electroencephalography; Female; Huma | 1972 |
[Present status and future problems of stereoencephalotomy].
Topics: Athetosis; Brain; Brain Neoplasms; Chorea; Dihydroxyphenylalanine; Epilepsy; Humans; Myoclonus; Park | 1971 |
Infantile spasms and hypopigmented macules. Early manifestations of tuberous sclerosis.
Topics: Biopsy; Catechol Oxidase; Child; Child, Preschool; Dihydroxyphenylalanine; Female; Histocytochemistr | 1971 |