dihydroxyphenylalanine has been researched along with Muscle Contraction in 35 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves for acetylcholine with and without dopamine, isoprenaline, phenylephrine and noradrenaline were obtained." | 1.25 | The depressor effect of dopamine on the electrical and mechanical activities of cat small intestine. ( Okawa, H; Wantanabe, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (94.29) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katai, R | 1 |
| Tsuneyoshi, I | 1 |
| Hamasaki, J | 1 |
| Onomoto, M | 1 |
| Suehiro, S | 1 |
| Sakata, R | 1 |
| Kanmura, Y | 1 |
| Yamada, K | 1 |
| Demarest, KT | 1 |
| Moore, KE | 1 |
| Barrow, CJ | 1 |
| Doleman, MS | 1 |
| Bobko, MA | 1 |
| Cooper, R | 1 |
| Sjöström, A | 1 |
| Zangger, P | 1 |
| Okawa, H | 1 |
| Wantanabe, M | 1 |
| Mori, S | 1 |
| Russell, DF | 1 |
| Zajac, FE | 1 |
| Clineschmidt, BV | 1 |
| Pettibone, DJ | 1 |
| Lotti, VJ | 1 |
| Hucker, HB | 1 |
| Sweeney, BM | 1 |
| Reiss, DR | 1 |
| Lis, EV | 1 |
| Huff, JR | 1 |
| Vacca, J | 1 |
| Roby-Brami, A | 1 |
| Bussel, B | 1 |
| Fukuda, H | 1 |
| Maeyama, K | 1 |
| Ito, Y | 1 |
| Watanabe, T | 1 |
| Wada, H | 1 |
| Higgins, DC | 1 |
| Haidri, NH | 1 |
| Wilbourn, AJ | 1 |
| McLellan, DL | 2 |
| Phillips, SJ | 1 |
| Richens, A | 1 |
| Shand, DG | 1 |
| Bennett, JM | 1 |
| Blum, K | 1 |
| Pendleton, RG | 1 |
| Kaiser, C | 1 |
| Gessner, G | 1 |
| Finlay, E | 1 |
| Green, H | 1 |
| Dietrichson, P | 2 |
| Pedersen, E | 1 |
| Gormsen, J | 1 |
| Arlien-Soborg, P | 1 |
| Goldberg, LI | 1 |
| Bieger, D | 2 |
| Larochelle, L | 1 |
| Hornykiewicz, O | 1 |
| Molina-Negro, P | 1 |
| Illingworth, RA | 1 |
| Andrews, CJ | 2 |
| Burke, D | 1 |
| Fromm, C | 1 |
| Noth, J | 1 |
| Delwaide, PJ | 1 |
| Schwab, RS | 1 |
| Young, RR | 1 |
| Caccia, MR | 1 |
| Avanzini, G | 1 |
| Negri, S | 1 |
| Ferko, AP | 1 |
| Calesnick, B | 1 |
| Grillner, S | 1 |
| Clementi, F | 1 |
| Naimzada, KM | 1 |
| Mantegazza, P | 1 |
| Buckley, NM | 1 |
| Gorokhov, AL | 1 |
| Osborne, MW | 1 |
| Wenger, JJ | 1 |
| Willems, W | 1 |
| Kastl, L | 1 |
| de Ropp, RS | 1 |
| Furst, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury[NCT04807764] | 45 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dihydroxyphenylalanine and Muscle Contraction
| Article | Year |
|---|---|
[The mechanism of locomotion (author's transl)].
Topics: Animals; Cats; Central Nervous System; Cerebellum; Diencephalon; Dihydroxyphenylalanine; Locomotion; | 1978 |
Cardiovascular and renal actions of dopamine: potential clinical applications.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Cats; Coronary Circulation; Dihydroxyphenylalanine; Do | 1972 |
33 other studies available for dihydroxyphenylalanine and Muscle Contraction
| Article | Year |
|---|---|
The variable effects of dopamine among human isolated arteries commonly used for coronary bypass grafts.
Topics: Adrenergic alpha-Antagonists; Arteries; Benzazepines; Cardiotonic Agents; Coronary Artery Bypass; Di | 2004 |
Effects of behaviorally active doses of thyrotropin-releasing hormone and its analog MK-771 on dopaminergic neuronal systems in the brain of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Corpus Striatum; Dihydroxyphenylal | 1984 |
Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-beta-hydroxytyrosine, isolated from Aspergillus flavipes.
Topics: Amino Acid Sequence; Animals; Aspergillus; Binding, Competitive; Dihydroxyphenylalanine; Guinea Pigs | 1994 |
Muscle spindle control during locomotor movements generated by the deafferented spinal cord.
Topics: Animals; Cats; Dihydroxyphenylalanine; Electric Stimulation; Hindlimb; Motor Neurons, Gamma; Movemen | 1976 |
The depressor effect of dopamine on the electrical and mechanical activities of cat small intestine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cats; | 1975 |
Effects of stimulating Deiters' nucleus and medial longitudinal fasciculus on the timing of the fictive locomotor rhythm induced in cats by DOPA.
Topics: Aminopyridines; Animals; Cats; Dihydroxyphenylalanine; Dominance, Cerebral; Electric Stimulation; Hi | 1979 |
A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood-Brain Barrier; Callitrichinae; Cl | 1988 |
Long-latency spinal reflex in man after flexor reflex afferent stimulation.
Topics: Adolescent; Adult; Animals; Cats; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Fe | 1987 |
Long-term depletion of histamine in guinea-pigs by administration of alpha-fluoromethylhistidine, a specific inhibitor of histidine decarboxylase; effect on the sensitivity of histamine receptors.
Topics: Adenylyl Cyclases; Animals; Carboxy-Lyases; Dihydroxyphenylalanine; Guinea Pigs; Histamine; Histidin | 1988 |
Muscle silent period in Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Electromyography; Female; Humans; Male; Middle Aged; Muscle Contractio | 1971 |
Dynamic spindle reflexes and the rigidity of Parkinsonism.
Topics: Adult; Aged; Dihydroxyphenylalanine; Electric Stimulation; Female; Humans; Male; Middle Aged; Muscle | 1973 |
Adrenergic control of tendon jerk reflexes in man.
Topics: Blood Pressure; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Humans; Methamphetam | 1973 |
Relation of dopa and 5-HTP to convulsions induced by strychnine and leptazol.
Topics: 5-Hydroxytryptophan; Animals; Anura; Dihydroxyphenylalanine; Injections, Subcutaneous; Muscle Contra | 1970 |
The effect of dopamine and other catecholamines on neuromuscular transmission.
Topics: Animals; Anura; Blood Pressure; Carotid Arteries; Cats; Depression, Chemical; Dihydroxyphenylalanine | 1969 |
Studies on SK and F 7698; an inhibitor of phenylethanolamine N-methyltransferase (PNMT).
Topics: Adrenal Glands; Animals; Aorta, Thoracic; Blood Pressure; Brain Chemistry; Carbon Radioisotopes; Dih | 1974 |
Treatment of Parkinsonism with L-dopa and decarboxylase inhibitors. An electrophysiological study.
Topics: Ankle Joint; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Combinations | 1972 |
Measurement of phasic and tonic stretch reflexes in antispastic and antiparkinsonian therapy.
Topics: Achilles Tendon; Action Potentials; Aminobutyrates; Computers, Analog; Cryosurgery; Depression, Chem | 1974 |
A model for the quantitative study of central dopaminergic and serotoninergic activity.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine; | 1972 |
Influence of striatal dopamine receptor blockade on a bulbar motor reaction.
Topics: Animals; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Electric Stimul | 1974 |
[Preliminary report on the action of cyclobenzaprine (MK-130) in Parkinson's disease].
Topics: Activities of Daily Living; Aged; Dibenzocycloheptenes; Dihydroxyphenylalanine; Electromyography; Fe | 1973 |
Quantitative study of the effect of L-dopa and phenoxybenzamine on the rigidity of Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Electromyography; Female; Humans; Male; Middle Aged; Muscle Contractio | 1973 |
Influence of dystonia on the response to long-term L-dopa therapy in Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Electromyography; Evaluation Studies as | 1973 |
Autogenetic inhibition of gamma-motoneurons in the spinal cat uncovered by Dopa injection.
Topics: Achilles Tendon; Animals; Axons; Cats; Decerebrate State; Dihydroxyphenylalanine; Electric Stimulati | 1974 |
Polysynaptic spinal reflexes in Parkinson's disease.
Topics: Aged; Amantadine; Dihydroxyphenylalanine; Drug Combinations; Electromyography; Female; Humans; Male; | 1974 |
Levodopa in Parkinsonism: reduction in the electromyographic silent period and its relationship with tremor.
Topics: Adult; Aged; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Female; Humans; Male; M | 1972 |
An electrophysiological study of some trigeminofacial reflexes in Parkinson's disease before and after L-dopam administration.
Topics: Analysis of Variance; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Evaluation Stu | 1972 |
L-DOPA and dopamine on skeletal muscle.
Topics: Animals; Blood Pressure; Cats; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Edrophonium; | 1971 |
The influence of DOPA on the static and the dynamic fusimotor activity to the triceps surae of the spinal cat.
Topics: Action Potentials; Animals; Cattle; Cordotomy; Dihydroxyphenylalanine; Electric Stimulation; Electro | 1969 |
Study of the nerve endings in the vas deferens and seminal vesicle of the guinea pig.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dihydroxyphenylalanine; Electric Stimulation; Guanethi | 1969 |
Role of endogenous norepinephrine in cardiac inotropic effects of nucleosides.
Topics: Animals; Coronary Vessels; Dihydroxyphenylalanine; Heart; Heart Rate; In Vitro Techniques; Muscle Co | 1970 |
[The relationship between the activity of the sympatho-adrenal system during muscular activity and adaptation to it].
Topics: Adaptation, Physiological; Adrenal Glands; Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine | 1970 |
The cardiovascular pharmacology of L(--)-dopa: peripheral and central effects.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Body Surface Area; Cardiac Ou | 1971 |
Substituted catechols as convulsant and relaxant agents.
Topics: Animals; Benzoates; Cinnamates; Cornea; Dihydroxyphenylalanine; Drug Antagonism; Male; Mice; Motor A | 1969 |