dihydroxyphenylalanine has been researched along with Multiple Sclerosis in 9 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Lersy, F | 1 |
| Kremer, S | 1 |
| Chibbaro, S | 1 |
| Namer, IJ | 1 |
| Bund, C | 1 |
| STERN, P | 1 |
| ZEC, N | 1 |
| Matthews, WB | 1 |
| Booker, HE | 1 |
| Dahl, DS | 1 |
| Leon, AS | 1 |
| Spiegel, HE | 1 |
| Yahr, MD | 1 |
| Potvin, AR | 1 |
| Albers, JW | 1 |
| Repa, BS | 1 |
| Henderson, WG | 1 |
| Walker, JE | 1 |
| Stribley, RF | 1 |
| Tourtellotte, WW | 1 |
| Ziegler, DK | 1 |
| Schimke, RN | 1 |
| Kepes, J | 1 |
| Rose, D | 1 |
| Klinkerfuss, G | 1 |
| Birkmayer, W | 1 |
3 reviews available for dihydroxyphenylalanine and Multiple Sclerosis
| Article | Year |
|---|---|
Advances in neurology.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Anticonvulsants; Antihypertens | 1972 |
L-dopa in neurological disease: current status.
Topics: Aged; Amyotrophic Lateral Sclerosis; Basal Ganglia Diseases; Cerebellar Diseases; Cerebrovascular Di | 1972 |
Quantitative evaluation of neuropharmacological trials.
Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin | 1974 |
1 trial available for dihydroxyphenylalanine and Multiple Sclerosis
| Article | Year |
|---|---|
Quantitative evaluation of neuropharmacological trials.
Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin | 1974 |
6 other studies available for dihydroxyphenylalanine and Multiple Sclerosis
| Article | Year |
|---|---|
18 F-FDOPA and MRI Findings in a Case of Multiple Sclerosis.
Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Magnetic Res | 2022 |
[The treatment of diseases accompanied by intention tremor symptoms (Preliminary report)].
Topics: Antihypertensive Agents; Dihydroxyphenylalanine; Hepatolenticular Degeneration; Humans; Multiple Scl | 1963 |
Clinical neurology.
Topics: Basal Ganglia; Cerebrovascular Disorders; Coma; Diagnosis, Differential; Dihydroxyphenylalanine; Hum | 1971 |
The effect of antacid administration on the absorption and metabolism of levodopa.
Topics: Administration, Oral; Adult; Antacids; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Female; | 1972 |
A familial neurological disease with symptomatic response to levodopa.
Topics: Adult; Amyotrophic Lateral Sclerosis; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Human | 1971 |
[The measurement of kinetic energy in movement accomplishment].
Topics: Dihydroxyphenylalanine; Humans; Injections, Intravenous; Movement; Movement Disorders; Multiple Scle | 1967 |