dihydroxyphenylalanine has been researched along with Movement Disorders in 233 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
Excerpt | Relevance | Reference |
---|---|---|
" All patients entering the trial were taking anticholinergic drugs in stable dosage and these were continued throughout." | 2.64 | L-dopa in Parkinsonism and the influence of previous thalamotomy. ( Hughes, RC; Polgar, JG; Walton, JN; Weightman, D, 1971) |
" Improvement was sustained during this period even though the average daily dosage of L-dopa was reduced." | 2.63 | Treatment of Parkinsonism with Laevo-dopa. ( Mawdsley, C, 1970) |
"Among the motor tetrad of Parkinson's disease, akinesia is not easy to define and controversies still exist on the nature of akinesia." | 2.39 | Clinicophysiological features of akinesia. ( Imai, H, 1996) |
"Strategies in treatment of movement disorders are discussed with the illustration of three patients with dystonia." | 1.33 | Treatment strategies in movement disorders. ( Speelman, JD, 2005) |
"We characterized the clinical dose-response curves for relief of parkinsonism and production of dyskinesias as a function of plasma levodopa and 3-O-methyldopa levels in six patients with advanced Parkinson's disease (PD) and fluctuating responses to oral levodopa/carbidopa." | 1.29 | Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease. ( Bennett, JP; Schuh, LA, 1993) |
"Five patients with Parkinson's disease, unilaterally transplanted with foetal mesencephalic cells into putamen (n=1) or putamen and caudate (n=4), were followed throughout a period of 15-36 months after surgery, according to the recommendations of the core assessment programme for intracerebral transplantations (CAPIT)." | 1.29 | Long-term outcome of unilaterally transplanted parkinsonian patients. I. Clinical approach. ( Cesaro, P; Defer, GL; Degos, JD; Fenelon, G; Gaston, A; Geny, C; Jeny, R; Keravel, Y; Monfort, JC; Nguyen, JP; Peschanski, M; Remy, P; Ricolfi, F; Samson, Y; Villafane, G, 1996) |
"While the Parkinson's disease patients had a decreased uptake of [18F]fluorodopa in the striatum but no abnormality in the glucose metabolism." | 1.28 | Positron emission tomography (PET) in "pure akinesia". ( Fujii, N; Goto, I; Hasuo, K; Hosokawa, S; Ichiya, Y; Kato, M; Kuwabara, Y; Otsuka, M; Taniwaki, T, 1992) |
"A series of 203 patients with primary Parkinson's disease treated with L-DOPA, with adequate neurological documentation of mental status at serial intervals during their illness, constitutes the study population." | 1.27 | Dementia in idiopathic Parkinson's disease. Variables associated with its occurrence in 203 patients. ( Elizan, TS; Maker, H; Smith, H; Sroka, H; Yahr, MD, 1986) |
"Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects." | 1.26 | CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977) |
"Haloperidol was used in 12 patients in an attempt to improve l-dopa induced dyskinesias." | 1.25 | Attempted use of haloperidol in the treatment of L-dopa induced dyskinesias. ( Klawans, HL; Weiner, WJ, 1974) |
"In monkeys with resting tremor, the administration of DL-5-HTP (5-hydroxytryptophan) or of DL-DOPA (3,4-dihydroxyphenylalanine) relieves the tremor, but the simultaneous administration of DL-5-HTP or DL-DOPA and atropine results in a much more pronounced relief." | 1.25 | The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions. ( Anagnoste, B; Battista, AF; Goldstein, M; Nakatani, S, 1969) |
"Nausea and cardiac arrhythmias are lessened, as are the incidence and severity of hypotension." | 1.25 | Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease. ( Barbeau, A; Botez, MI; Joubert, M; Mars, H, 1972) |
" Patients with postencephalitic Parkinsonism may respond as well as patients with Parkinson's disease to levodopa but they develop both favourable responses and side-effects at a lower dosage and require careful dosage adjustments and close surveillance." | 1.25 | Response of patients with postencephalitic Parkinsonism to levodopa. ( Duvoisin, RC; Lobo-Antunes, J; Yahr, MD, 1972) |
" Some of the common side effects of l-dopa administration can be averted or controlled by a cautious and slow build-up to the optimal dosage level." | 1.25 | Treatment of Parkinson's disease with L-dopa: a current appraisal. ( Kofman, O, 1971) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 213 (91.42) | 18.7374 |
1990's | 11 (4.72) | 18.2507 |
2000's | 7 (3.00) | 29.6817 |
2010's | 2 (0.86) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Pretze, M | 1 |
Wängler, C | 1 |
Wängler, B | 1 |
Poewe, W | 1 |
Scherfler, C | 1 |
Tolosa, E | 1 |
Marek, K | 1 |
Kuriakose, R | 1 |
Stoessl, AJ | 2 |
Seibyl, JP | 2 |
ERNST, AM | 1 |
ROOS, BE | 1 |
STEG, G | 3 |
HIRSCHMANN, J | 2 |
MAYER, K | 2 |
Speelman, JD | 1 |
Gorman, JM | 1 |
Chen, W | 1 |
Silverman, DH | 1 |
Scheel-Krüger, J | 1 |
Randrup, A | 2 |
Wöller, W | 1 |
Tegeler, J | 1 |
Di Capua, M | 1 |
Bertini, E | 1 |
Schuh, LA | 1 |
Bennett, JP | 1 |
Narabayashi, H | 1 |
Defer, GL | 1 |
Geny, C | 1 |
Ricolfi, F | 1 |
Fenelon, G | 1 |
Monfort, JC | 1 |
Remy, P | 1 |
Villafane, G | 1 |
Jeny, R | 1 |
Samson, Y | 1 |
Keravel, Y | 1 |
Gaston, A | 1 |
Degos, JD | 1 |
Peschanski, M | 1 |
Cesaro, P | 1 |
Nguyen, JP | 1 |
Pahwa, R | 1 |
Lyons, K | 1 |
McGuire, D | 1 |
Dubinsky, R | 1 |
Hubble, JP | 1 |
Koller, WC | 1 |
Imai, H | 1 |
Otsuka, M | 2 |
Ichiya, Y | 2 |
Kuwabara, Y | 2 |
Hosokawa, S | 2 |
Sasaki, M | 1 |
Yoshida, T | 1 |
Fukumura, T | 1 |
Masuda, K | 1 |
Kato, M | 2 |
Katayama, Y | 1 |
Ilgin, N | 1 |
Ruottinen, HM | 1 |
Partinen, M | 1 |
Hublin, C | 1 |
Bergman, J | 1 |
Haaparanta, M | 1 |
Solin, O | 1 |
Rinne, JO | 1 |
de la Fuente-Fernández, R | 1 |
Pal, PK | 1 |
Vingerhoets, FJ | 1 |
Kishore, A | 1 |
Schulzer, M | 1 |
Mak, EK | 1 |
Ruth, TJ | 1 |
Snow, BJ | 1 |
Calne, DB | 6 |
Davidson, DL | 1 |
Yates, CM | 1 |
Mawdsley, C | 2 |
Pullar, IA | 2 |
Wilson, H | 1 |
Gonce, M | 1 |
Barbeau, A | 10 |
Shoulson, I | 1 |
Glaubiger, GA | 1 |
Chase, TN | 8 |
Janzik, HH | 1 |
Papavasiliou, PS | 2 |
Miller, ST | 2 |
Cotzias, GC | 4 |
Kraner, HW | 1 |
Hsieh, RS | 1 |
Wilimowski, M | 1 |
Witkowska, M | 1 |
Barczyńska, J | 1 |
Kedzierska, L | 1 |
Orzechowska-Juzwenko, K | 1 |
Wojewódzki, W | 1 |
Felsztyńska, J | 1 |
Taniwaki, T | 1 |
Goto, I | 1 |
Fujii, N | 1 |
Hasuo, K | 1 |
Barker, R | 1 |
Elizan, TS | 4 |
Sroka, H | 1 |
Maker, H | 1 |
Smith, H | 1 |
Yahr, MD | 3 |
Martin, WR | 1 |
Lieberman, AN | 2 |
Pedersen, B | 1 |
Critchley, EM | 1 |
Klawans, HC | 1 |
Paulson, GW | 3 |
Fleming, P | 1 |
Makar, H | 1 |
Hunter, KR | 3 |
Stern, GM | 4 |
Sharkey, J | 1 |
Weiss, JL | 2 |
Ng, LK | 2 |
Parkes, JD | 3 |
Baxter, RC | 2 |
Curzon, G | 3 |
Knill-Jones, RP | 1 |
Knott, PJ | 1 |
Marsden, CD | 5 |
Tattersall, R | 1 |
Vollum, D | 1 |
Birkmayer, W | 6 |
Neumayer, E | 1 |
Eckstein, B | 1 |
Shaw, K | 1 |
Stern, G | 1 |
Fehling, C | 1 |
Woods, AC | 1 |
Shaw, KM | 1 |
Laurence, DR | 2 |
McCaul, JA | 1 |
Bulandra, R | 1 |
Serbanesco, A | 1 |
Gellene, R | 1 |
Wagshul, A | 1 |
Daroff, RB | 1 |
Spiers, AS | 1 |
Harner, RN | 1 |
Dorman, RM | 1 |
Villeneuve, A | 1 |
Böszörményi, Z | 1 |
Van Woert, MH | 3 |
Heninger, G | 1 |
Rathey, U | 1 |
Bowers, MB | 1 |
Schmitt, FO | 1 |
Cook, DG | 1 |
Fahn, S | 2 |
Brait, KA | 1 |
Mones, RJ | 7 |
Pasik, P | 1 |
Pasik, T | 1 |
Wilk, S | 1 |
Jurna, I | 2 |
Lanzer, G | 1 |
Theres, C | 1 |
Bachmann, T | 1 |
Schnur, JA | 1 |
Brody, JA | 2 |
Hartmann-von Monakow, K | 3 |
Papeschi, R | 1 |
Molina-Negro, P | 1 |
Sourkes, TL | 2 |
Erba, G | 1 |
Klawans, HL | 7 |
Constantinidis, J | 1 |
Rondot, P | 4 |
Dumas, RJ | 1 |
Korczyn, AD | 1 |
Linauer, W | 1 |
Mentasti, M | 1 |
Riederer, P | 1 |
Re', O | 1 |
Klawans, H | 1 |
Ilahi, MM | 1 |
Shenker, D | 1 |
Bird, MT | 1 |
Sigwald, J | 3 |
Chomette, G | 1 |
Raymondeaud, C | 2 |
Ziegler, DK | 1 |
Schimke, RN | 1 |
Kepes, JJ | 1 |
Rose, DL | 1 |
Klinkerfuss, G | 1 |
Brogden, RN | 1 |
Speight, TM | 1 |
Avery, GS | 1 |
Lance, JW | 1 |
Andrews, C | 1 |
Cramer, H | 1 |
Cooper, IS | 2 |
Larochelle, L | 2 |
Bédard, P | 2 |
Poirier, LJ | 2 |
Gordon, N | 1 |
Saïd, G | 2 |
McKenzie, GM | 1 |
Gordon, RJ | 1 |
Viik, K | 1 |
Reid, JL | 3 |
Sweet, RD | 1 |
McDowell, FH | 1 |
Dupont, E | 2 |
Hansen, E | 2 |
Melsens, S | 1 |
Parkenberg, H | 1 |
Holm, P | 1 |
Boudin, G | 2 |
Pépin, B | 2 |
Guillard, A | 2 |
Fabiani, JM | 1 |
Haguenau, M | 1 |
Völler, GW | 2 |
Muschard, F | 2 |
Ngai, SH | 1 |
Vakil, SD | 1 |
Allen, JG | 2 |
Davies, CA | 2 |
Nittner, K | 2 |
Deze, J | 1 |
Gundlach, U | 1 |
Franken, L | 1 |
Noel, G | 1 |
Lhoas, JP | 1 |
Meyers, C | 1 |
Noel, P | 1 |
Ectors, M | 1 |
Rinne, UK | 2 |
Boshes, B | 1 |
Sathananthan, G | 1 |
Angrist, BM | 1 |
Gershon, S | 1 |
Gerlach, J | 1 |
Reisby, N | 1 |
Velasco, F | 1 |
Velasco, M | 1 |
Andrews, CJ | 1 |
Somerville, B | 1 |
Rosati, G | 1 |
Agnetti, V | 1 |
Mura, F | 1 |
Granieri, E | 1 |
Lombard, M | 1 |
Tardieu, G | 1 |
Haleem, MA | 1 |
Lyons, JB | 1 |
Kastin, AJ | 1 |
Groneberg, P | 1 |
Struppler, A | 1 |
Castaigne, P | 3 |
Rascol, A | 1 |
Ribadeau-Dumas, JL | 2 |
Géraud, J | 1 |
David, J | 1 |
Mahoudeau, D | 1 |
Singer, B | 1 |
Gilbert, JC | 1 |
Goulon, M | 1 |
Gajdos, P | 1 |
Sacks, OW | 2 |
Kohl, MS | 1 |
Messeloff, CR | 2 |
Schwartz, WF | 2 |
Proctor, P | 1 |
Reveno, WS | 1 |
Bauer, RB | 1 |
Rosenbaum, H | 1 |
Tissot, R | 2 |
de Ajuriaguerra, J | 2 |
Schneider, E | 1 |
Fischer, PA | 1 |
Jacobi, P | 1 |
Maxion, H | 1 |
Ambani, LM | 1 |
Selby, G | 1 |
Mano, T | 2 |
Holden, EM | 1 |
Hildick-Smith, M | 1 |
Harik, SI | 1 |
Morris, PL | 1 |
Lhermitte, F | 2 |
Rosa, A | 1 |
Comoy, E | 1 |
Bohuon, C | 1 |
Stoliarova, LG | 1 |
Kistenev, BA | 1 |
Duvoisin, RC | 4 |
Rees, JE | 2 |
Kantamaneni, BD | 1 |
Knill-Jones, R | 1 |
Akbar, A | 1 |
Das, S | 1 |
Kataria, M | 1 |
Weiner, WJ | 1 |
Gauthier, G | 2 |
Juge, O | 1 |
Birchler, A | 1 |
Dolphin, A | 1 |
Jenner, P | 1 |
Tarsy, D | 1 |
Sutcliffe, RL | 1 |
Miller, E | 1 |
Siegfried, J | 2 |
Klaiber, R | 1 |
Perret, E | 1 |
Ziegler, WH | 1 |
Sandler, M | 1 |
Sugita, K | 1 |
Mutsuga, N | 1 |
Takaoka, Y | 1 |
Takeda, A | 1 |
Timberlake, WH | 2 |
Muenter, MD | 1 |
Hughes, RC | 1 |
Polgar, JG | 1 |
Weightman, D | 1 |
Walton, JN | 1 |
Ahmad, R | 1 |
Gillingham, FJ | 1 |
Hanieh, A | 1 |
Weddell, J | 1 |
Ashcroft, G | 1 |
Velasco Suárez, MM | 1 |
Escobedo, FR | 1 |
Lipman, IJ | 1 |
Beck, H | 1 |
Marteau, R | 1 |
Raphy, B | 1 |
Sonninen, V | 1 |
Siirtola, T | 1 |
Fujita, S | 1 |
Mann, DC | 1 |
Pearce, LA | 1 |
Waterbury, LD | 1 |
Godwin-Austen, RB | 1 |
Bergmann, S | 1 |
Frears, CC | 1 |
Giuffrè, R | 2 |
Gambacorta, D | 1 |
Pakkenberg, H | 1 |
Garde, B | 1 |
Melsen, S | 1 |
Vestberg, F | 1 |
Goldstein, M | 2 |
Battista, AF | 2 |
Nakatani, S | 1 |
Anagnoste, B | 1 |
Ogawa, M | 1 |
Altrocchi, PH | 1 |
Garron, DC | 1 |
Narin, F | 1 |
Critchley, E | 2 |
Degkwitz, R | 1 |
Mars, H | 3 |
Botez, MI | 1 |
Joubert, M | 1 |
Libman, I | 1 |
Schwartz, AM | 1 |
Gillo-Joffroy, L | 2 |
Silfverskiöld, BP | 1 |
Lobo-Antunes, J | 1 |
Ikeda, H | 1 |
Baba, O | 1 |
Ishino, H | 1 |
Guggenheim, MA | 2 |
Couch, JR | 1 |
Weinberg, W | 1 |
North, RR | 1 |
McKendall, RR | 1 |
Ericsson, AD | 3 |
Guidetti, B | 1 |
Jenkins, AC | 1 |
Schwieger, AC | 1 |
Ringel, SP | 1 |
Boggan, WO | 1 |
Seiden, LS | 1 |
Newkirk, TA | 1 |
Magee, KR | 1 |
Greenburg, J | 1 |
Longo, V | 1 |
Kemali, D | 1 |
Pacini, A | 1 |
Bertolino, A | 1 |
Lamura, G | 1 |
Siegel, GJ | 2 |
Greenhouse, AH | 1 |
Wertman, BG | 2 |
Duffy, KM | 1 |
Mena, I | 1 |
Court, J | 1 |
Gutmann, L | 1 |
Martin, JD | 1 |
Gutrecht, JA | 1 |
Martin, WE | 1 |
Umbach, W | 3 |
Tzavellas, O | 1 |
Garvin, JS | 1 |
Kaufmann, W | 1 |
Butz, P | 1 |
Wiesendanger, M | 1 |
Yaryura-Tobias, JA | 1 |
Wolpert, A | 1 |
Dana, L | 1 |
Merlis, S | 1 |
Celesia, GG | 1 |
Barr, AN | 1 |
Dodge, PR | 1 |
Siegel, G | 1 |
Radouco-Thomas, S | 1 |
Bergamini, L | 1 |
Bonzanino, O | 1 |
Brignolio, F | 1 |
Fabiani, A | 1 |
Fariello, R | 1 |
Mombelli, AM | 1 |
Mutani, R | 1 |
Pisani, W | 1 |
Postir, A | 1 |
Quattroccolo, G | 1 |
Riccio, A | 1 |
Sabbatini, F | 1 |
Sandigliano, G | 1 |
Schiffer, D | 1 |
Mandell, S | 1 |
Weintraub, MI | 1 |
Kofman, O | 1 |
Tang, LC | 1 |
Ginos, JZ | 1 |
Bioulac, B | 1 |
Richer, E | 1 |
Metzel, A | 1 |
Holldorf, A | 1 |
Bischoff, A | 1 |
Spiegel, EA | 1 |
Szekely, EG | 1 |
Zivanovic, D | 1 |
Gaillard, JM | 1 |
Guggisberg, M | 1 |
Schear, MJ | 1 |
Barrett, RE | 1 |
Hoehn, MM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Evaluation of 5-[123I]-A-85380 and SPECT Imaging as a Marker of Nicotinic Receptor Density in the Brain of Parkinson Disease Subjects[NCT00397696] | Phase 2 | 9 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
STEM-PD Trial: A Multicentre, Single Arm, First in Human, Dose-escalation Trial, Investigating the Safety and Tolerability of Intraputamenal Transplantation of Human Embryonic Stem Cell Derived Dopaminergic Cells for Parkinson's Disease (STEM-PD Product)[NCT05635409] | Phase 1 | 8 participants (Anticipated) | Interventional | 2022-11-30 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
30 reviews available for dihydroxyphenylalanine and Movement Disorders
Article | Year |
---|---|
6-[18F]fluoro-L-DOPA: a well-established neurotracer with expanding application spectrum and strongly improved radiosyntheses.
Topics: Brain Neoplasms; Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Disorders; Radioactive T | 2014 |
Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications.
Topics: Animals; Biomarkers; Cerebrovascular Circulation; Corpus Striatum; Dihydroxyphenylalanine; Disease P | 2010 |
Imaging studies in movement disorders.
Topics: Brain; Cocaine; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disorders; Parkinson Disease; Pre | 2003 |
3,4-dihydroxy-6-[18f]-fluoro-L-phenylalanine positron emission tomography in patients with central motor disorders and in evaluation of brain and other tumors.
Topics: Adrenal Gland Neoplasms; Amino Acids; Brain Neoplasms; Caudate Nucleus; Dihydroxyphenylalanine; Fluo | 2007 |
The neural mechanisms and progressive nature of symptoms of Parkinson's disease--based on clinical, neurophysiological and morphological studies.
Topics: Dihydroxyphenylalanine; Disease Progression; Dyskinesia, Drug-Induced; Humans; Levodopa; Movement Di | 1995 |
Clinicophysiological features of akinesia.
Topics: Dihydroxyphenylalanine; Dopamine Agents; Humans; Movement Disorders; Parkinson Disease; Treatment Ou | 1996 |
[Functional neurosurgery with an implantable and programmable pulse-generator: control of involuntary movement disorders].
Topics: Brain; Dihydroxyphenylalanine; Electric Stimulation; Electrodes, Implanted; Humans; Movement Disorde | 1997 |
Functional imaging of neurotransmitter systems in movement disorders.
Topics: Brain; Carrier Proteins; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Protei | 1998 |
[The current treatment of Parkinson's disease].
Topics: Amantadine; Antidepressive Agents, Tricyclic; Dihydroxyphenylalanine; Drug Combinations; Histamine A | 1976 |
Positron emission tomography in movement disorders.
Topics: Brain; Cerebrovascular Circulation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dystonia; Glu | 1985 |
[Modern treatment of parkinsonism].
Topics: Antiparkinson Agents; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Gastroin | 1972 |
Promising trends in neuroscience.
Topics: Animal Communication; Animals; Axonal Transport; Brain; Cerebellar Cortex; Crowding; Culture Techniq | 1970 |
The biochemistry of dyskinesias.
Topics: Acetylcholine; Animals; Catecholamines; Cats; Copper; Dihydroxyphenylalanine; Dogs; Hepatolenticular | 1967 |
Pathological aspects on Parkinson's syndrome.
Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System; Chlorpromazine; Corpus Stria | 1972 |
The pharmacology of extrapyramidal movement disorders.
Topics: Basal Ganglia Diseases; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Hep | 1973 |
Pathophysiology of drug-induced dyskinesias.
Topics: Brain; Brain Chemistry; Butyrophenones; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Do | 1972 |
2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action.
Topics: Acetylcholine; Blood-Brain Barrier; Brain Chemistry; Carbon Radioisotopes; Child; Choline; Deanol; D | 1974 |
Theoretical implications of the use of L-dopa in parkinsonism. A review.
Topics: Acetylcholine; Amantadine; Animals; Cats; Dihydroxyphenylalanine; Dopamine; Female; Haplorhini; Huma | 1970 |
Levodopa: a review of its pharmacological properties and therapeutic use with particular reference to Parkinsonism.
Topics: Amantadine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia Diseases; Brain Che | 1971 |
Drug-induced extrapyramidal disorders.
Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopa | 1972 |
Antiparkinsonian drugs: pharmacological and therapeutic aspects.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Amantadine; Amphetamine; Antiparkinson Agents; Apomorphi | 1972 |
Parkinsonism, levodopa, and anesthesia.
Topics: Amantadine; Anesthesia; Animals; Apomorphine; Benperidol; Blood-Brain Barrier; Brain; Cardiovascular | 1972 |
Recent advances in the treatment of Parkinsonism with drugs.
Topics: Amantadine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Blood-Brain | 1972 |
Therapeutic uses and side effects of L-dopa.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Barbiturates; Dihydroxyphenylalanine; Drug Synergism; | 1972 |
[Biochemical and clinical correlations in Parkinson's disease].
Topics: Brain; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Movement Disorders; Norepinephri | 1972 |
L-Dopa and Parkinsonism.
Topics: Basal Ganglia; Blood-Brain Barrier; Clinical Trials as Topic; Delusions; Dihydroxyphenylalanine; Dop | 1970 |
Parkinson's disease. II.
Topics: Basal Ganglia; Catecholamines; Dihydroxyphenylalanine; Gait; Humans; Mental Processes; Movement Diso | 1970 |
L-dopa therapy in Parkinson's disease.
Topics: Delirium; Depression; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Hallucinations; Humans; H | 1971 |
Observations on the range of efficacy of L-dopa.
Topics: Brain Diseases; Brain Stem; Cerebellar Diseases; Dementia; Dihydroxyphenylalanine; Dopamine; Extrapy | 1971 |
Levodopa in Parkinsonism.
Topics: Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Humans; Hypotension; Movem | 1971 |
31 trials available for dihydroxyphenylalanine and Movement Disorders
Article | Year |
---|---|
Early morning akinesia in Parkinson's disease: effect of standard carbidopa/levodopa and sustained-release carbidopa/levodopa.
Topics: Aged; Carbidopa; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Dihydroxyphenyla | 1996 |
Levodopa in drug-induced extrapyramidal disorders.
Topics: Dihydroxyphenylalanine; Extrapyramidal Tracts; Fluphenazine; Humans; Movement Disorders; Orphenadrin | 1970 |
Sustained-release levodopa in parkinsonism.
Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Dihydroxyphenylalanine; Humans; Middle | 1973 |
Letter: Lithium in Parkinson's disease.
Topics: Carbonates; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Antagonism; Drug Evaluation; Drug | 1974 |
Modification of Parkinsonism--chronic treatment with L-dopa.
Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blo | 1969 |
L-dopa in idiopathic parkinsonism.
Topics: Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Hypotension, Orthostatic; Mental Disorders | 1969 |
Treatment of drug-induced dyskinesias.
Topics: Aged; Dihydroxyphenylalanine; Humans; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease | 1970 |
[10 years of L-DOPA therapy of Parkinson's syndrome].
Topics: Administration, Oral; Amphetamine; Animals; Brain Chemistry; Catecholamines; Clinical Trials as Topi | 1971 |
[2-year experiences with a combination treatment of Parkinsonism with L-dopa and a decarboxylase inhibitor (Benserazid, Ro 4-4602)].
Topics: Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Dermatitis, Seborrheic; Dihydroxyphenylalanin | 1974 |
Plasma concentration of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase.
Topics: Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Hydrazines; Male; Methyldo | 1972 |
[Clinical study of L-dopa in Parkinson's disease].
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Clinical Trials as Topic; Dihydroxyph | 1972 |
Response threshold to levodopa in psychiatric patients.
Topics: Adult; Brain Chemistry; Clinical Trials as Topic; Cognition Disorders; Dihydroxyphenylalanine; Dopam | 1973 |
Dopaminergic hypersensitivity and cholinergic hypofunction in the pathophysiology of tardive dyskinesia.
Topics: Adult; Age Factors; Aged; Biperiden; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Fem | 1974 |
A quantitative evaluation of the effects of L-dopa on Parkinson's disease.
Topics: Arm; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Movement; Movement Disorders; Muscle | 1973 |
Levodopa combined with MK 486 (L-alpha methyldopahydrazine)--a peripheral decarboxylase inhibitor in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Thera | 1974 |
[Treatment of Parkinsonic syndrome with levo-Dopa. Case reports].
Topics: Arteriosclerosis; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Female; Humans; | 1974 |
[Therapeutic trial of rigidity-akinesia in children using L-Dopa].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Dihydroxyphenylalanine; | 1973 |
[Treatment of Parkinson's disease with L-dopa combined with a decarboxylase inhibitor].
Topics: Animals; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Enzyme Re | 1969 |
Treatment of Parkinsonism with Laevo-dopa.
Topics: Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; | 1970 |
L-Dopa and Parkinsonism.
Topics: Basal Ganglia; Blood-Brain Barrier; Clinical Trials as Topic; Delusions; Dihydroxyphenylalanine; Dop | 1970 |
[Effects of L-dopa and stereotaxic surgery in Parkinsonism].
Topics: Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Mo | 1970 |
Double-blind comparison of levodopa and procyclidine in parkinsonism, with illustrations of levodopa-induced movement disorders.
Topics: 1-Propanol; Adult; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Middle Ag | 1970 |
Double-blind, placebo-controlled study of levodopa therapy in Parkinson's disease.
Topics: Clinical Trials as Topic; Dihydroxyphenylalanine; Disability Evaluation; Humans; Male; Mental Proces | 1970 |
L-dopa in Parkinsonism and the influence of previous thalamotomy.
Topics: Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypertension; Hypotension; M | 1971 |
Double-blind comparison of levodopa and procyclidine in parkinsonism, with illustrations of levodopa-induced movement disorders.
Topics: 1-Propanol; Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Mid | 1970 |
[Treatment of Parkinson's disease with L-dopa. 77 cases].
Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Dihydroxyphenylalanine; | 1970 |
L-Dopa treatment in Parkinson's Disease.
Topics: Age Factors; Anorexia Nervosa; Cardiovascular Diseases; Clinical Trials as Topic; Dihydroxyphenylala | 1970 |
Effects of L-dopa on the H-reflex in parkinsonism.
Topics: Adult; Aged; Chronaxy; Clinical Trials as Topic; Dihydroxyphenylalanine; Electric Stimulation; Femal | 1971 |
Amantadine for Parkinson's disease.
Topics: Aged; Amantadine; Amines; Brain; Clinical Trials as Topic; Dihydroxyphenylalanine; Disability Evalua | 1971 |
Effect of age and arteriosclerosis on the response of Parkinsonian patients to levodopa.
Topics: Age Factors; Aged; Antiemetics; Arteriosclerosis; Clinical Trials as Topic; Dihydroxyphenylalanine; | 1971 |
[Levodopa and Parkinsonism. A double-blind study].
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Dihydroxyphenylalanine; | 1971 |
173 other studies available for dihydroxyphenylalanine and Movement Disorders
Article | Year |
---|---|
Supplement neuroimaging movement disorders.
Topics: Diagnostic Imaging; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Movement Disorders; | 2009 |
Phenomena of the hypokinetic rigid type caused by o-methylation of dopamine in the para-position.
Topics: Dihydroxyphenylalanine; Dopamine; Humans; Methylation; Movement Disorders | 1962 |
THE EFFECT OF L-3, 4-DIHYDROXYPHENYLALANINE AND DL-5-HYDROXYTRYPTOPHAN ON RIGIDITY AND TREMOR INDUCED BY RESERPINE, CHLORPROMAZINE AND PHENOXYBENZAMINE.
Topics: 5-Hydroxytryptophan; Amino Acids; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Inulin; Movement | 1964 |
[ON THE CONTROL OF AKINESIA AND OTHER EXTRAPYRAMIDAL MOTOR DISORDERS WITH L-DOPA (L-DIHYDROXYPHENYLALANINE)].
Topics: Chorea; Dihydroxyphenylalanine; Electromyography; Extrapyramidal Tracts; Humans; Levodopa; Monoamine | 1964 |
[NEW MEANS OF CONTROLLING EXTRAPYRAMIDAL MOTOR DISORDERS].
Topics: Central Nervous System Diseases; Dihydroxyphenylalanine; Drug Therapy; Electroencephalography; Extra | 1964 |
Treatment strategies in movement disorders.
Topics: Adult; Botulinum Toxins; Cerebral Palsy; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; | 2005 |
More to movement disorders than motion.
Topics: Basal Ganglia; Deep Brain Stimulation; Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Di | 2006 |
Stereotype hyperactive behaviour produced by dopamine in the absence of noradrenaline.
Topics: Animals; Behavior, Animal; Brain Chemistry; Carbamates; Catecholamines; Dihydroxyphenylalanine; Dopa | 1967 |
[Tardive dyskinesia: clinical picture, prevalence, and pathophysiology].
Topics: Age Factors; Antipsychotic Agents; Diagnosis, Differential; Dihydroxyphenylalanine; Dyskinesia, Drug | 1983 |
Remission in dihydroxyphenylalanine-responsive dystonia.
Topics: Child; Dihydroxyphenylalanine; Dystonia; Humans; Levodopa; Male; Movement Disorders; Treatment Outco | 1995 |
Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Carbidopa; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Dru | 1993 |
Long-term outcome of unilaterally transplanted parkinsonian patients. I. Clinical approach.
Topics: Aged; Antiparkinson Agents; Brain; Brain Tissue Transplantation; Dihydroxyphenylalanine; Female; Fet | 1996 |
Differences in the reduced 18F-Dopa uptakes of the caudate and the putamen in Parkinson's disease: correlations with the three main symptoms.
Topics: Adult; Aged; Caudate Nucleus; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; | 1996 |
An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome.
Topics: Adult; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; | 2000 |
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations.
Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Levo | 2000 |
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; | 1977 |
On-off response. Clinical and biochemical correlations during oral and intravenous levodopa administration in parkinsonian patients.
Topics: Administration, Oral; Aged; Blood Pressure; Dihydroxyphenylalanine; Dose-Response Relationship, Drug | 1975 |
[Drug-induced extrapyramidal symptoms].
Topics: Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Basal Ganglia Diseases; Contracepti | 1975 |
Sequential analysis: manganese, catecholamines and L-dopa induced dyskinesia.
Topics: Animals; Brain Chemistry; Cats; Caudate Nucleus; Cerebral Cortex; Corpus Callosum; Dihydroxyphenylal | 1975 |
Central action of 2-amino- and 2-amino-5-aryltetrahydropyrimidinediones-4,6.
Topics: Amphetamine; Analgesia; Animals; Central Nervous System; Dihydroxyphenylalanine; Drug Synergism; Fem | 1975 |
Positron emission tomography (PET) in "pure akinesia".
Topics: Adult; Aged; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Female; Glucose; Humans; Magnetic Re | 1992 |
Neuropathological features of Alzheimer's disease in non-demented parkinsonian patients.
Topics: Alzheimer Disease; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders; Parkinson Disea | 1992 |
Dementia in idiopathic Parkinson's disease. Variables associated with its occurrence in 203 patients.
Topics: Age Factors; Aged; Dementia; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Dis | 1986 |
Levodopa and adventitious movements.
Topics: Amyotrophic Lateral Sclerosis; Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease | 1970 |
Naturally occurring dyskinesias.
Topics: Dihydroxyphenylalanine; Female; Humans; Intellectual Disability; Male; Movement Disorders; Tranquili | 1970 |
Predictive test for Huntington's chorea.
Topics: Dihydroxyphenylalanine; Humans; Huntington Disease; Movement Disorders; Neurologic Examination; Neur | 1970 |
Levodopa in postencephalitic parkinsonism.
Topics: Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Disorders; Parkinson Disease, Postencepha | 1970 |
L-dopa. II.
Topics: Anorexia Nervosa; Cardiac Complexes, Premature; Dihydroxyphenylalanine; Drug Synergism; Humans; Hypo | 1970 |
Long-lasting dyskinesia induced by levodopa.
Topics: Adult; Dihydroxyphenylalanine; Female; Humans; Injections; Injections, Intramuscular; Movement Disor | 1971 |
Treatment of Parkinson's disease with amantadine and levodopa. A one-year study.
Topics: Aged; Amantadine; Blood Vessels; Dihydroxyphenylalanine; Edema; Female; Gastrointestinal Diseases; H | 1971 |
Treatment of Parkinson's syndrome with L-DOPA on an out-patient basis.
Topics: Age Factors; Aged; Ambulatory Care; Dihydroxyphenylalanine; Female; Humans; Hypotension, Orthostatic | 1972 |
M.I.F.: effect on levodopa dyskinesias in man.
Topics: Antiparkinson Agents; Carbidopa; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Dose-Respo | 1973 |
Sustained levodopa therapy in parkinsonism.
Topics: Activities of Daily Living; Aged; Cognition Disorders; Dihydroxyphenylalanine; Drug Evaluation; Faci | 1973 |
Letter: Pyridoxine in parkinsonism.
Topics: Dihydroxyphenylalanine; Drug Antagonism; Drug Interactions; Humans; Metoclopramide; Movement Disorde | 1973 |
[Dopamine and the parkinsonism-chorea antagonism].
Topics: Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disorders; Parkinson Disease; Phenothiazi | 1972 |
L-dopa for progressive supranuclear palsy.
Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders | 1969 |
Mechanisms of electroencephalographic and behavioral changes produced by parenteral L-DOPA.
Topics: Animals; Bradycardia; Cats; Cerebral Cortex; Defecation; Dihydroxyphenylalanine; Electroencephalogra | 1969 |
L-dopa in senile dementia.
Topics: Aged; Aphrodisiacs; Brain; Dementia; Dihydroxyphenylalanine; Female; Humans; Movement Disorders; Par | 1970 |
Chronic manganese intoxication.
Topics: Adult; Diagnosis, Differential; Dihydroxyphenylalanine; Edetic Acid; Environmental Exposure; Evaluat | 1974 |
The modification of L-dopa induced dyskinesias in the monkey by unilateral nigral lesions.
Topics: Animals; Caudate Nucleus; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Haplorhini; Hydr | 1973 |
Alpha-rigidity in reserpinized rats.
Topics: Animals; Dihydroxyphenylalanine; Electromyography; Electrophysiology; Movement Disorders; Muscle Spi | 1964 |
[Experimental findings and new aspects in extrapyramidal diseases].
Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Do | 1966 |
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydro | 1969 |
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyogr | 1969 |
Parkinsonism-dementia of Guam: treatment with L-dopa.
Topics: Adult; Dementia; Dihydroxyphenylalanine; Drug Eruptions; Female; Humans; Hydroxyindoleacetic Acid; H | 1971 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases.
Topics: Adolescent; Adult; Basal Ganglia Diseases; Cerebral Palsy; Cerebral Ventricles; Diazepam; Dihydroxyp | 1972 |
[Monoamines and choreic syndromes].
Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus | 1972 |
[Dopamine and abnormal movements].
Topics: Benserazide; Body Weight; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Therapy, Combination; Electro | 1972 |
The rigid form of Huntington's chorea.
Topics: Adult; Age Factors; Amantadine; Dihydroxyphenylalanine; Female; Humans; Huntington Disease; Movement | 1971 |
[Antagonism and competition between Parkinson's syndrome and the chorea and athetosis syndrome. Clinical cases of the association (including an anatomoclinical case). The abnormal movements provoked by levodopa in Parkinsonian patients].
Topics: Adult; Athetosis; Basal Ganglia; Brain; Chorea; Dihydroxyphenylalanine; Female; Globus Pallidus; Hum | 1972 |
Late onset ataxia, rigidity, and peripheral neuropathy. A familial syndrome with variable therapeutic response to levodopa.
Topics: Adult; Aged; Brain; Cerebellar Ataxia; Dihydroxyphenylalanine; Electromyography; Female; Genes, Domi | 1972 |
Dysaesthesia-dyskinesia: a syndrome of painful legs and moving toes.
Topics: Aged; Amantadine; Amitriptyline; Chlorpromazine; Dihydroxyphenylalanine; Female; Humans; Leg; Moveme | 1973 |
Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease.
Topics: Adolescent; Adult; Aged; Cerebellar Diseases; Child; Cyclic AMP; Dihydroxyphenylalanine; Female; Hom | 1973 |
[Symposium on diseases of the basal ganglia. Physiological and clinical implications of thalamic surgery for dystonia and torticollis. II].
Topics: Adolescent; Adult; Basal Ganglia; Catecholamines; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1968 |
[Abnormal movements observed during treatment of Parkinson's disease with L-dopa].
Topics: Dihydroxyphenylalanine; Extremities; Face; Head; Humans; Mouth; Movement Disorders; Neck; Parkinson | 1970 |
Correlative neuroanatomical and neuropharmacological study of tremor and catatonia in the monkey.
Topics: Animals; Catatonia; Cerebellum; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Haplorhini; Human | 1971 |
Drugs and motor functions.
Topics: Athetosis; Catecholamines; Cholinesterase Inhibitors; Chorea; Dihydroxyphenylalanine; Dopamine; Extr | 1971 |
[Dystonias].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Extra | 1972 |
Some biochemical and behavioural correlates of a possible animal model of human hyperkinetic syndromes.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Catecholamines; Cats; Caudate Nucleus; Chlorpromaz | 1972 |
Plasma dopa concentrations and the "on-off" effect after chronic treatment of Parkinson's disease.
Topics: Dietary Proteins; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levod | 1974 |
Parkinson's disease treated with L-dopa. Three-year follow-up report.
Topics: Dihydroxyphenylalanine; Follow-Up Studies; Humans; Mental Disorders; Movement Disorders; Nausea; Par | 1972 |
Treatment of Parkinsonism with a combination of levodopa and the decarboxylase inhibitor and RO 46-4602 (a comparison with levodopa treatment alone).
Topics: Administration, Oral; Aromatic Amino Acid Decarboxylase Inhibitors; Capsules; Dihydroxyphenylalanine | 1972 |
[Indications and results of monoamine treatment in parkinsonian syndromes].
Topics: Aged; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; | 1972 |
Efficacy of and possible differences in tolerance to L-dopa tablets with different rates of release of the active substance.
Topics: Administration, Oral; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Drug Tolerance; Feeding and Eati | 1974 |
Hypokinetic syndromes and their therapy.
Topics: Basal Ganglia Diseases; Dihydroxyphenylalanine; Humans; Movement Disorders; Stereotaxic Techniques; | 1972 |
[Problems and therapy of L-DOPA-induced dyskinesias].
Topics: Adult; Age Factors; Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Disord | 1972 |
Hypokinetic syndromes and their therapy.
Topics: Dihydroxyphenylalanine; Electric Stimulation; Humans; Movement Disorders; Stereotaxic Techniques; Th | 1972 |
L-dopa in the treatment of parkinsonism.
Topics: Aged; Arrhythmias, Cardiac; Arteriosclerosis; Aspartate Aminotransferases; Blood Urea Nitrogen; Dihy | 1972 |
Involuntary movements.
Topics: Dihydroxyphenylalanine; Female; Humans; Ireland; Male; Movement Disorders; Phenothiazines | 1972 |
Preliminary clinical studies with L-prolyl-L-leucyl-glycine amide in Parkinson's disease.
Topics: Administration, Oral; Aged; Amides; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Glycine; H | 1972 |
[Treatment of Parkinson's disease and extrapyramidal syndromes with classical drugs (what can be expected from them in the levodopa era and which should be used)].
Topics: Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; Humans; Movement Disorders; Pa | 1972 |
[The therapeutic effect of L-dopa].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Asthma; Brain; Dihydroxyphenylalanine; Dopamine; Human | 1972 |
[Effect of L-dopa in familial sporadic dystonia in children].
Topics: Adolescent; Adult; Child; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders | 1972 |
[The use of levodopa in diseases other than Parkinsonism].
Topics: Chorea; Coma; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Endocrine System Diseases; Hear | 1972 |
[Shy-Drager disease. Hemodynamic and pharmacodynamic studies. Value of cyproheptadine].
Topics: Cyproheptadine; Dihydroxyphenylalanine; Fecal Incontinence; Female; Humans; Hypotension, Orthostatic | 1972 |
Effects of levodopa in Parkinsonian patients with dementia.
Topics: Aged; Delirium; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Male; Mental Di | 1972 |
Electron-transfer factors in psychosis and dyskinesia.
Topics: Blood Proteins; Bromides; Dihydroxyphenylalanine; Electron Transport; Epinephrine; Humans; Iron; Lip | 1972 |
L-dopa for parkinsonism.
Topics: Aged; Amantadine; Depression; Dihydroxyphenylalanine; Female; Follow-Up Studies; Hallucinations; Hum | 1973 |
[Parkinson's syndrome. 4 years of experience in treatment with L Dopa associated with a decarboxylase inhibitor. Clinical and biochemical study].
Topics: Benzyl Compounds; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Drug Combinations; Humans; Hyd | 1973 |
[Comparison of the effect of L-Dopa and of an L-Dopa+decarboxylase inhibitor combination in Parkinson's disease].
Topics: Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Drug Synergism; Female; Gastrointes | 1973 |
Levodopa and related drugs.
Topics: Amantadine; Apomorphine; Dihydroxyphenylalanine; Humans; Hydrazines; Hypotension; Mental Disorders; | 1973 |
Start hesitation--a side effect of long-term levodopa therapy.
Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Locomotion; Male; Middle Aged; Movement Disorders; Par | 1973 |
Levodopa in parkinson's disease--Australian collaborative trial.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Australia; Bone Marrow; Dihydroxyphenylalanine | 1973 |
[L-Dopa induced dyskinesia--electromyographic approaches].
Topics: Adult; Aged; Dihydroxyphenylalanine; Electromyography; Female; Humans; Male; Middle Aged; Movement D | 1973 |
Levodopa-induced dyskinesias. Comparison in Parkinsonism-dementia and amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbidopa; Dementia; Dihydroxyphenylalanine; Female; Hum | 1973 |
The patient's view of L-Dopa after one year's therapy.
Topics: Aged; Blood Pressure; Cognition Disorders; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; | 1973 |
The effects of lesions in the head of the caudate nucleus on spontaneous and L-DOPA induced activity in the cat.
Topics: Animals; Cats; Caudate Nucleus; Dihydroxyphenylalanine; Locomotion; Movement Disorders; Placebos | 1973 |
Failures of L-dopa.
Topics: Aged; Aging; Depression; Dihydroxyphenylalanine; Humans; Male; Medication Errors; Middle Aged; Movem | 1973 |
Drug-induced dyskinesia--an electrophysiological analysis of dyskinesia induced by L-DOPA and anticholinergic drugs.
Topics: Aged; Dihydroxyphenylalanine; Electromyography; Female; Humans; Male; Middle Aged; Movement Disorder | 1973 |
[Abnormal movements induced by L-Dopa and dopamine metabolism disorders].
Topics: Benzoates; Dihydroxyphenylalanine; Dopamine; Electrocoagulation; Female; Homovanillic Acid; Humans; | 1973 |
[Treatment of parkinsonism with the drug L-DOPA].
Topics: Brain Diseases; Dihydroxyphenylalanine; Hepatolenticular Degeneration; Humans; Movement Disorders; P | 1973 |
Parkinson's disease: a clinical review.
Topics: Adult; Aged; Brain Diseases; Bulbar Palsy, Progressive; Dementia; Diagnosis, Differential; Dihydroxy | 1974 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose | 1974 |
Parkinson's disease, cerebral arteriosclerosis, and senile dementia. Clinical features and response to levodopa.
Topics: Aged; Dementia; Dihydroxyphenylalanine; Electroencephalography; Female; Gait; Homovanillic Acid; Hum | 1974 |
Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease.
Topics: Aged; Amantadine; Cognition Disorders; Dihydroxyphenylalanine; Drug Therapy, Combination; Edema; Eye | 1974 |
Attempted use of haloperidol in the treatment of L-dopa induced dyskinesias.
Topics: Adult; Aged; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; M | 1974 |
Parkinsonian syndromes. Treatment by association of L-dopa plus decarboxylase inhibitor.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Decarboxylation; Depression; Depressio | 1974 |
Role of noradrenaline in levodopa reversal of reserpine akinesia.
Topics: Animals; Chlorpromazine; Dihydroxyphenylalanine; Haloperidol; Mice; Movement Disorders; Norepinephri | 1974 |
The treatment of parkinsonism with levodopa.
Topics: Aged; Anorexia Nervosa; Basal Ganglia Diseases; Depression; Dihydroxyphenylalanine; Extrapyramidal T | 1974 |
Deanol in the treatment of levodopa-induced dyskinesias.
Topics: Aged; Antidepressive Agents; Deanol; Dihydroxyphenylalanine; Ethanolamines; Female; Humans; Male; Ma | 1974 |
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homov | 1974 |
Akinesis following stereotactic surgery for Parkinsonism. The use of L-dopa.
Topics: Adult; Aged; Dihydroxyphenylalanine; Drug Tolerance; Female; Globus Pallidus; Humans; Male; Middle A | 1970 |
Stereotaxic intracerebral instillation of dopa.
Topics: Caudate Nucleus; Dihydroxyphenylalanine; Electroencephalography; Humans; Methods; Movement Disorders | 1970 |
The therapeutic possibilities of L-dopa and amantadine in Parkinsonian patients who have undergone bilateral thalamotomy.
Topics: Adolescent; Adult; Aged; Amantadine; Child; Dihydroxyphenylalanine; Electroencephalography; Female; | 1971 |
The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergi | 1969 |
Rationale for the use of L-dopa in the torsion dystonias.
Topics: Animals; Basal Ganglia; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Haplorhini; | 1970 |
[Motor and psychomotor activity of striatal monoamines].
Topics: Animals; Basal Ganglia; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Glob | 1970 |
Production of involuntary movements by L-dopa in monkeys with tegmental lesions.
Topics: Animals; Carboxy-Lyases; Dihydroxyphenylalanine; Disease Models, Animal; Haplorhini; Mesencephalon; | 1971 |
Spontaneous oral-facial dyskinesia.
Topics: Basal Ganglia; Dihydroxyphenylalanine; Facial Muscles; Female; Humans; Male; Masticatory Muscles; Mi | 1972 |
Intellectual functioning of persons with idiopathic Parkinsonism.
Topics: Aged; Cerebral Cortex; Computers; Dementia; Dihydroxyphenylalanine; Evaluation Studies as Topic; Fem | 1972 |
Levodopa and amantadine in the treatment of Parkinsonism.
Topics: Aged; Amantadine; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Disorders; Nau | 1972 |
[Drug-induced Parkinson's syndrome].
Topics: Acetylcholinesterase; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disor | 1972 |
Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Benzyl Compounds; D | 1972 |
Clinical manifestations of essential tremor.
Topics: Adult; Aged; Amantadine; Ataxia; Chlordiazepoxide; Dihydroxyphenylalanine; Female; Humans; Male; Mep | 1972 |
L-DOPA in Parkinson's disease. Results of a co-operative study in the Montreal area.
Topics: Administration, Oral; Aged; Basal Ganglia Diseases; Constipation; Dihydroxyphenylalanine; Evaluation | 1972 |
[Disturbed equilibrium in chronic alcoholism].
Topics: Adult; Alcoholism; Ataxia; Dihydroxyphenylalanine; Electromyography; Gait; Humans; Leg; Movement Dis | 1972 |
Response of patients with postencephalitic Parkinsonism to levodopa.
Topics: Aged; Dihydroxyphenylalanine; Encephalitis; Evaluation Studies as Topic; Female; Humans; Hypotension | 1972 |
[L-dopa induced psychosis-dyskinesia complex].
Topics: Dihydroxyphenylalanine; Female; Humans; Middle Aged; Movement Disorders; Neurologic Manifestations; | 1972 |
Motor dysfunction as a permanent complication of methanol ingestion. Presentation of a case with a beneficial response to levodopa treatment.
Topics: Adolescent; Dihydroxyphenylalanine; Female; Humans; Methanol; Motor Cortex; Movement Disorders; Opti | 1971 |
Drug-induced movement disorders.
Topics: Amphetamine; Contraceptives, Oral; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Hu | 1971 |
L-dopa--long-term effects.
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease | 1971 |
Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia.
Topics: Aged; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Facial Muscles; Female; Haloperidol; Humans; | 1971 |
Potentiation of the L-Dopa effect in man by the use of catechol-O-methyltransferase inhibitors.
Topics: Adult; Brain; Catechols; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Methyltransferases; | 1971 |
A year's experience of L-DOPA in the treatment of Parkinson's disease.
Topics: Adult; Age Factors; Aged; Dihydroxyphenylalanine; Female; Functional Laterality; Humans; Hypotension | 1971 |
Therapeutic guidelines and side effects encountered during L-dopa therapy in 100 cases of parkinsonism.
Topics: Carboxy-Lyases; Circadian Rhythm; Dihydroxyphenylalanine; Drug Resistance; Female; Gastrointestinal | 1971 |
Observations on the efficacy of L-dopa in progressive supranuclear palsy.
Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Disorders; Ophthalmoplegia | 1971 |
Dopa reversal of reserpine enhancement of audiogenic seizure susceptibility in mice.
Topics: Animals; Behavior, Animal; Benzyl Compounds; Brain Chemistry; Dihydroxyphenylalanine; Dopa Decarboxy | 1971 |
[Conservative therapy in the Parkinson syndrome].
Topics: Amantadine; Antidepressive Agents; Dihydroxyphenylalanine; Humans; Imipramine; Injections, Intraveno | 1971 |
[Treatment of the Parkinson syndrome with amantadine].
Topics: Adult; Aged; Amantadine; Arteriosclerosis; Cognition Disorders; Dihydroxyphenylalanine; Drug Interac | 1971 |
Treatment of parkinsonism with levo-dopa: results in 302 cases.
Topics: Aged; Dihydroxyphenylalanine; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Hypotens | 1971 |
Side effects of L-dopa treatment.
Topics: Aphrodisiacs; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Disorders; Nausea; | 1971 |
Relationship of plasma concentrations of levodopa to clinical response in Parkinsonsim.
Topics: Administration, Oral; Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease | 1971 |
[Evaluation in clinical trials of some drug associations. (L-dopa, neuroleptics and lithium carbonate)].
Topics: Basal Ganglia Diseases; Dihydroxyphenylalanine; Extrapyramidal Tracts; Humans; Lithium; Mental Disor | 1971 |
Analysis of L-dopa induced dyskinesias in 51 patients with Parkinsonism.
Topics: Adult; Aged; Basal Ganglia; Dihydroxyphenylalanine; Dopamine; Humans; Middle Aged; Movement Disorder | 1971 |
Manganese intoxication in the United States.
Topics: Dihydroxyphenylalanine; Humans; Male; Manganese Poisoning; Movement Disorders; Psychoses, Substance- | 1971 |
Reversal of the reserpine syndrome with L-dopa metabolites in reserpinized rats.
Topics: Animals; Central Nervous System; Dihydroxyphenylalanine; Motor Skills; Movement Disorders; Normetane | 1971 |
Sensitivity studies of L-dopa metabolites in reserpinized rats and their clinical significance.
Topics: Animals; Brain; Catechols; Dihydroxyphenylalanine; Female; Humans; Male; Mandelic Acids; Middle Aged | 1971 |
Levodopa, involuntary movements and fusaric acid.
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Norepinephrine; Parkinson Disease; Picolinic Aci | 1971 |
L-Dopa therapy of Parkinson's disease. (A review of the preliminary experience at West Virginia University).
Topics: Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders; Nausea; Parkinson Disease; Vomitin | 1970 |
Adverse clinical side effects of levodopa therapy.
Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede | 1971 |
Adverse reactions during treatment of Parkinson's disease with levodopa.
Topics: Adult; Aged; Coombs Test; Depression; Dihydroxyphenylalanine; Duodenal Ulcer; Female; Gastrointestin | 1971 |
Different effects of drugs before and after stereotaxic operation.
Topics: Amphetamine; Dihydroxyphenylalanine; Globus Pallidus; Humans; Movement Disorders; Parkinson Disease; | 1966 |
[Clinical and electromyographic controls of the effect of dopamine in parkinsonian patients].
Topics: Blood Pressure; Dihydroxyphenylalanine; Electroencephalography; Electromyography; Humans; Movement D | 1967 |
Treatment of parkinsonism with L-dopa (study of 105 patients).
Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Anorexia Nervosa; Aspartate Aminotransfe | 1969 |
[Effect of a combined L-Dopa and decarboxylase inhibitor (Ro 4-4602) therapy in parkinsonism patients. Quantitative analysis of bradykinesia using reaction times].
Topics: Aged; Carboxy-Lyases; Desipramine; Dihydroxyphenylalanine; Discrimination, Psychological; Drug Syner | 1969 |
An evaluation of L-dopa in Parkinson patients.
Topics: Deglutition; Dihydroxyphenylalanine; Gait; Humans; Hypotension; Movement Disorders; Parkinson Diseas | 1969 |
A second report on Levodopa.
Topics: Amantadine; Arrhythmias, Cardiac; Cerebrovascular Disorders; Dihydroxyphenylalanine; Humans; Hypoten | 1969 |
[Therapy of extrapyramidal-motor symptoms. Drug treatment].
Topics: Alkaloids; Atropa belladonna; Dihydroxyphenylalanine; Extrapyramidal Tracts; Humans; Monoamine Oxida | 1969 |
Action of L-Dopa in drug induced extrapyramidalism.
Topics: Adult; Chlorpromazine; Chronic Disease; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Human | 1970 |
Psychosis and other psychiatric manifestations of levodopa therapy.
Topics: Adult; Aged; Anxiety; Depression; Dihydroxyphenylalanine; Euphoria; Female; Humans; Male; Middle Age | 1970 |
Long-term effects of levodopa in the severely disabled patient.
Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders; Parkinson Disease; Parkins | 1970 |
[Two years experience with L-DOPA in association with a decarboxylase inhibitor].
Topics: Acute Disease; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Hypoten | 1970 |
L-dopa. I.
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Paralysis; Parkinson Disease | 1970 |
Unusual arm movements with onset in childhood--a nosologic entity?
Topics: Child; Diagnosis, Differential; Diazepam; Dihydroxyphenylalanine; Diphenhydramine; Dystonia Musculor | 1970 |
L-dopa induced dyskinesias in 152 patients with Parkinson's disease.
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease | 1970 |
[Extrapyramidal syndrome in animal experiments: rôle of calcium and o-methylated derivatives].
Topics: Animals; Calcium; Calcium Metabolism Disorders; Depression, Chemical; Dihydroxyphenylalanine; Dopami | 1970 |
[Experiences in the treatment of Parkinsonism with L-dopa. IV. Effects on the experimental extrapyranidal brady-akinesia in cats].
Topics: Animals; Cats; Caudate Nucleus; Dihydroxyphenylalanine; Disease Models, Animal; Extrapyramidal Tract | 1970 |
The treatment of dystonia with L-dopa and haloperidol.
Topics: Adolescent; Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Haloperidol | 1970 |
Importance and pathogenesis of abnormal movements during L-dopa therapy of Parkinson's disease.
Topics: Administration, Oral; Animals; Dihydroxyphenylalanine; Haloperidol; Humans; Movement Disorders; Musc | 1970 |
An analysis of L-dopa-induced dyskinesias in 152 cases of Parkinson's disease.
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease; Thalamus | 1970 |
Reversal by levodopa of cholinergic hypersensitivity in Parkinson's disease.
Topics: Brain; Dihydroxyphenylalanine; Dopamine; Drug Hypersensitivity; Female; Handwriting; Humans; Injecti | 1971 |
Treatment of Parkinson's disease with L-dopa: a current appraisal.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Dihydroxyphenylalanine; Follow-Up Studies; Humans; Male; M | 1971 |
Melatonin and abnormal movements induced by L-dopa in mice.
Topics: Administration, Oral; Animals; Apomorphine; Brain Chemistry; Caudate Nucleus; Dihydroxyphenylalanine | 1971 |
[Attempted treatment with L-dopa in motor disorders during prolonged coma].
Topics: Adolescent; Adult; Coma; Craniocerebral Trauma; Dihydroxyphenylalanine; Humans; Male; Movement Disor | 1971 |
[Progressive extra-pyramidal disorder in 2 young brothers. Remarkable effects of treatment with L-dopa].
Topics: Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Dihydroxyphenylalanine; Extrapyram | 1971 |
Differentiation of tardive dyskinesias and drug-induced Parkinsonism.
Topics: Amantadine; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Hyperkinesis; Movement Disorder | 1971 |
The effect of methyldopa on the excretion of catecholamines in patients with extrapyramidal disorders.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epin | 1967 |
[Effect of L-DOPA on the akinesis in Parkinson's syndrome].
Topics: Dihydroxyphenylalanine; Humans; Movement Disorders; Parkinson Disease | 1967 |
[The measurement of kinetic energy in movement accomplishment].
Topics: Dihydroxyphenylalanine; Humans; Injections, Intravenous; Movement; Movement Disorders; Multiple Scle | 1967 |
Striatal bradykinesia alleviated by intracaudate injection of L-dopa.
Topics: Aluminum; Animals; Caudate Nucleus; Dihydroxyphenylalanine; Electrophysiology; Locomotion; Movement | 1968 |
[Treatment of Parkinsonism with oral L-DOPA combined with a decarboxylase inhibitor (Ro IV 46.02)].
Topics: Adult; Aged; Anemia, Hemolytic; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Cell Count; Carb | 1969 |
Treatment of parkinsonism with levodopa.
Topics: Adult; Aged; Anorexia Nervosa; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Female; Gait; Humans; H | 1969 |