Page last updated: 2024-10-18

dihydroxyphenylalanine and Melanosis

dihydroxyphenylalanine has been researched along with Melanosis in 10 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Melanosis: Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.

Research Excerpts

ExcerptRelevanceReference
"Melasma is an acquired brown hypermelanosis of the face."1.26Melasma: a clinical, light microscopic, ultrastructural, and immunofluorescence study. ( Fitzpatrick, TB; Mihm, MC; Pathak, MA; Sanchez, JL; Sanchez, NP; Sato, S, 1981)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanchez, NP1
Pathak, MA1
Sato, S1
Fitzpatrick, TB1
Sanchez, JL1
Mihm, MC1
Mizoguchi, M1
Murakami, F1
Ito, M1
Asano, M1
Baba, T1
Kawa, Y1
Kubota, Y1
Tsukamoto, K1
Furue, M1
Sato, Y1
Takayama, O1
Akasu, R1
Ohtake, N1
Wakamatsu, K1
Ito, S1
Tamaki, K1
Shimada, S1
Kimura, T1
Doi, K1
Mishima, Y1
Ruiz-Maldonado, R1
Tamayo, L1
Fernández-Diez, J1
Balabanow, K1
Tschernosemski, I1
Durmischev, AL1
Schleger, AV1
Whitehead, WJ1
Moyer, DG1
Vander Ploeg, DE1
Sohn, N1
Gang, H1
Gumport, SL1
Goldstein, M1
Deppisch, LM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Trichloroacetic Acid (TCA) Combined With Microdermabrasion in Treatment of Melasma[NCT04823520]Phase 460 participants (Anticipated)Interventional2021-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for dihydroxyphenylalanine and Melanosis

ArticleYear
Melasma: a clinical, light microscopic, ultrastructural, and immunofluorescence study.
    Journal of the American Academy of Dermatology, 1981, Volume: 4, Issue:6

    Topics: Adult; Bromides; Dihydroxyphenylalanine; Female; Fluorescent Antibody Technique; Humans; Melanocytes

1981
Clinical, pathological, and etiologic aspects of acquired dermal melanocytosis.
    Pigment cell research, 1997, Volume: 10, Issue:3

    Topics: Adult; Age of Onset; Animals; Biomarkers; Cells, Cultured; Child; Dihydroxyphenylalanine; Endothelin

1997
Generalized melanosis in metastatic malignant melanoma: the possible role of DOPAquinone metabolites.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:4

    Topics: Aged; Benzoquinones; Dihydroxyphenylalanine; Fatal Outcome; Genital Neoplasms, Male; Humans; Male; M

1998
Efficacy of hydroquinone in the treatment of cutaneous hyperpigmentation in hairless descendants of Mexican hairless dogs (Xoloitzcuintli).
    Laboratory animal science, 1998, Volume: 48, Issue:5

    Topics: Animals; Animals, Newborn; Cell Count; Dihydroxyphenylalanine; Dog Diseases; Dogs; Female; Hydroquin

1998
Histopathology of functional pigmentary disorders.
    Cutis, 1978, Volume: 21, Issue:2

    Topics: Albinism; Animals; Cricetinae; Dihydroxyphenylalanine; Female; Humans; Infant; Melanocytes; Melanosi

1978
Universal acquired melanosis. The carbon baby.
    Archives of dermatology, 1978, Volume: 114, Issue:5

    Topics: Adolescent; Child, Preschool; Dihydroxyphenylalanine; Female; Histiocytes; Humans; Infant; Infant, N

1978
[Studies of the pigmentation in 2 clinical cases of Riehl's melanosis].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1969, Volume: 44, Issue:14

    Topics: Dihydroxyphenylalanine; Face; Female; Histocytochemistry; Humans; Melanins; Melanosis; Middle Aged;

1969
Histopathology of melanotic sheep liver. 2. Enzymic histochemistry.
    Australian veterinary journal, 1970, Volume: 46, Issue:2

    Topics: Acid Phosphatase; Aminopeptidases; Animals; Dihydroxyphenylalanine; Electron Transport Complex IV; E

1970
Idiopathic guttate hypomelanosis.
    Archives of dermatology, 1966, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Child; Child, Preschool; Dihydroxyphenylalanine;

1966
Generalized melanosis secondary to malignant melanoma. Report of a case with serum and tissue tyrosinase studies.
    Cancer, 1969, Volume: 24, Issue:5

    Topics: Catechol Oxidase; Dihydroxyphenylalanine; Female; Humans; Lung Neoplasms; Melanins; Melanoma; Melano

1969