dihydroxyphenylalanine has been researched along with Lymph Node Metastasis in 14 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Homovanillic acid (HVA) was determined both in 45 patients with different forms of melanoma and those hospitalized on the suspicion of melanoma and in 15 healthy persons." | 8.75 | Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin. ( Ivanova, VD; Raushenbakh, MO; Trapeznikov, NN; Yavorsky, VV, 1975) |
| "The production of 5-S-cysteinyldopa by a newly established melanoma cell line GAK is reported." | 7.67 | [A newly established melanoma cell line (GAK) with 5-S-cysteinyldopa phenotype]. ( Kano, S; Kurihara, S; Nozawa, S; Ohta, H; Tsukazaki, K; Udagawa, Y, 1984) |
| "To determine whether plasma 5-S-cysteinyldopa levels are useful in following up patients at risk for melanoma, we measured plasma 5-S-cysteinyldopa in patients with dysplastic nevus syndrome and/or malignant melanoma and in control subjects." | 7.67 | Plasma 5-S-cysteinyldopa differentiates patients with primary and metastatic melanoma from patients with dysplastic nevus syndrome and normal subjects. ( Fletcher, WS; Ilias, A; Palmquist, M; Peterson, LL; Tucker, MA; Woodward, WR, 1988) |
| "Cysteinyldopas and Dopa in the urine and tissues of Japanese melanoma patients were investigated quantitatively by means of high-performance liquid chromatography." | 7.66 | Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma. ( Fujita, M; Fukada, E; Hanawa, S; Morishima, T; Nagashima, N; Saito, M; Tatsumi, F, 1983) |
| "Determinations of the urinary excretion of 5-S-cysteinyldopa were performed in 571 patients previously treated by surgery for melanoma or melanoma metastasis." | 7.66 | 5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis. ( Agrup, G; Agrup, P; Andersson, T; Hafström, L; Hansson, C; Jacobsson, S; Jönsson, PE; Rorsman, H; Rosengren, AM; Rosengren, E, 1979) |
| "Homovanillic acid (HVA) was determined both in 45 patients with different forms of melanoma and those hospitalized on the suspicion of melanoma and in 15 healthy persons." | 4.75 | Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin. ( Ivanova, VD; Raushenbakh, MO; Trapeznikov, NN; Yavorsky, VV, 1975) |
| "The production of 5-S-cysteinyldopa by a newly established melanoma cell line GAK is reported." | 3.67 | [A newly established melanoma cell line (GAK) with 5-S-cysteinyldopa phenotype]. ( Kano, S; Kurihara, S; Nozawa, S; Ohta, H; Tsukazaki, K; Udagawa, Y, 1984) |
| "To determine whether plasma 5-S-cysteinyldopa levels are useful in following up patients at risk for melanoma, we measured plasma 5-S-cysteinyldopa in patients with dysplastic nevus syndrome and/or malignant melanoma and in control subjects." | 3.67 | Plasma 5-S-cysteinyldopa differentiates patients with primary and metastatic melanoma from patients with dysplastic nevus syndrome and normal subjects. ( Fletcher, WS; Ilias, A; Palmquist, M; Peterson, LL; Tucker, MA; Woodward, WR, 1988) |
| "Cysteinyldopas and Dopa in the urine and tissues of Japanese melanoma patients were investigated quantitatively by means of high-performance liquid chromatography." | 3.66 | Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma. ( Fujita, M; Fukada, E; Hanawa, S; Morishima, T; Nagashima, N; Saito, M; Tatsumi, F, 1983) |
| "Determinations of the urinary excretion of 5-S-cysteinyldopa were performed in 571 patients previously treated by surgery for melanoma or melanoma metastasis." | 3.66 | 5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis. ( Agrup, G; Agrup, P; Andersson, T; Hafström, L; Hansson, C; Jacobsson, S; Jönsson, PE; Rorsman, H; Rosengren, AM; Rosengren, E, 1979) |
| "Distinguishing a SPM from carcinoid lesions is therefore important." | 1.35 | Combining 6-fluoro-[18F]l-dihydroxyphenylalanine and [18F]fluoro-2-deoxy-d-glucose positron emission tomography for distinction of non-carcinoid malignancies in carcinoid patients. ( Brouwers, AH; de Vries, EG; Fiebrich, HB; Koopmans, KP, 2009) |
| "The localization of carcinoids in the gastrointestinal tract is frequently difficult if not impossible with the imaging procedures used to date." | 1.30 | Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography. ( Hoegerle, S; Kraft, A; Moser, E; Nitzsche, EU; Schneider, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brammen, L | 1 |
| Niederle, MB | 1 |
| Riss, P | 1 |
| Scheuba, C | 1 |
| Selberherr, A | 1 |
| Karanikas, G | 1 |
| Bodner, G | 1 |
| Koperek, O | 1 |
| Niederle, B | 1 |
| Terroir, M | 1 |
| Grimaldi, S | 1 |
| Hartl, D | 1 |
| Leboulleux, S | 1 |
| Deandreis, D | 1 |
| Piccardo, A | 1 |
| Lopci, E | 1 |
| Conte, M | 1 |
| Cabria, M | 1 |
| Cistaro, A | 1 |
| Garaventa, A | 1 |
| Villavecchia, G | 1 |
| Liu, CJ | 1 |
| Lu, MY | 1 |
| Liu, YL | 1 |
| Ko, CL | 1 |
| Ko, KY | 1 |
| Tzen, KY | 1 |
| Chang, HH | 1 |
| Yang, YL | 1 |
| Jou, ST | 1 |
| Hsu, WM | 1 |
| Yen, RF | 1 |
| Fiebrich, HB | 1 |
| Brouwers, AH | 1 |
| Koopmans, KP | 1 |
| de Vries, EG | 1 |
| Langsteger, W | 1 |
| Heinisch, M | 1 |
| Fogelman, I | 1 |
| Morishima, T | 1 |
| Tatsumi, F | 1 |
| Fukada, E | 1 |
| Saito, M | 1 |
| Fujita, M | 1 |
| Nagashima, N | 1 |
| Hanawa, S | 1 |
| Nozawa, S | 1 |
| Ohta, H | 1 |
| Tsukazaki, K | 1 |
| Udagawa, Y | 1 |
| Kurihara, S | 1 |
| Kano, S | 1 |
| Hoegerle, S | 2 |
| Schneider, B | 1 |
| Kraft, A | 1 |
| Moser, E | 2 |
| Nitzsche, EU | 1 |
| Altehoefer, C | 1 |
| Ghanem, N | 1 |
| Koehler, G | 1 |
| Waller, CF | 1 |
| Scheruebl, H | 1 |
| Nitzsche, E | 1 |
| Agrup, G | 1 |
| Agrup, P | 1 |
| Andersson, T | 1 |
| Hafström, L | 1 |
| Hansson, C | 1 |
| Jacobsson, S | 1 |
| Jönsson, PE | 1 |
| Rorsman, H | 2 |
| Rosengren, AM | 1 |
| Rosengren, E | 1 |
| Trapeznikov, NN | 1 |
| Raushenbakh, MO | 1 |
| Ivanova, VD | 1 |
| Yavorsky, VV | 1 |
| Peterson, LL | 1 |
| Woodward, WR | 1 |
| Fletcher, WS | 1 |
| Palmquist, M | 1 |
| Tucker, MA | 1 |
| Ilias, A | 1 |
| Falck, B | 1 |
| Jacobson, S | 1 |
| Olivecrona, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)[NCT05553041] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2023-08-07 | Recruiting | ||
| Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)[NCT05555550] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dihydroxyphenylalanine and Lymph Node Metastasis
| Article | Year |
|---|---|
The role of fluorodeoxyglucose, 18F-dihydroxyphenylalanine, 18F-choline, and 18F-fluoride in bone imaging with emphasis on prostate and breast.
Topics: Bone Neoplasms; Breast Neoplasms; Choline; Dihydroxyphenylalanine; Fluorine Radioisotopes; Fluorodeo | 2006 |
Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin.
Topics: Animals; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Lymphatic Metastasis; Melanoma; Phenylac | 1975 |
12 other studies available for dihydroxyphenylalanine and Lymph Node Metastasis
| Article | Year |
|---|---|
Medullary Thyroid Carcinoma: Do Ultrasonography and F-DOPA-PET-CT Influence the Initial Surgical Strategy?
Topics: Adolescent; Adult; Aged; Calcitonin; Carcinoma, Neuroendocrine; Child; Clinical Decision-Making; Dih | 2018 |
Parathyroid Glands Hyperplasias Mimicking Medullary Thyroid Carcinoma Metastatic Lymph Nodes on 18F-DOPA PET/CT.
Topics: Adult; Carcinoma, Neuroendocrine; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorine | 2019 |
Bone and lymph node metastases from neuroblastoma detected by 18F-DOPA-PET/CT and confirmed by posttherapy 131I-MIBG but negative on diagnostic 123I-MIBG scan.
Topics: 3-Iodobenzylguanidine; Bone Neoplasms; Child; Dihydroxyphenylalanine; Humans; Lymphatic Metastasis; | 2014 |
Risk Stratification of Pediatric Patients With Neuroblastoma Using Volumetric Parameters of 18F-FDG and 18F-DOPA PET/CT.
Topics: Adolescent; Child; Child, Preschool; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Female; | 2017 |
Risk Stratification of Pediatric Patients With Neuroblastoma Using Volumetric Parameters of 18F-FDG and 18F-DOPA PET/CT.
Topics: Adolescent; Child; Child, Preschool; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Female; | 2017 |
Risk Stratification of Pediatric Patients With Neuroblastoma Using Volumetric Parameters of 18F-FDG and 18F-DOPA PET/CT.
Topics: Adolescent; Child; Child, Preschool; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Female; | 2017 |
Risk Stratification of Pediatric Patients With Neuroblastoma Using Volumetric Parameters of 18F-FDG and 18F-DOPA PET/CT.
Topics: Adolescent; Child; Child, Preschool; Cone-Beam Computed Tomography; Dihydroxyphenylalanine; Female; | 2017 |
Combining 6-fluoro-[18F]l-dihydroxyphenylalanine and [18F]fluoro-2-deoxy-d-glucose positron emission tomography for distinction of non-carcinoid malignancies in carcinoid patients.
Topics: Adenocarcinoma; Aged; Carcinoid Tumor; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluo | 2009 |
Cysteinyldopa isomers and dopa in lesions and urine of Japanese patients with malignant melanoma.
Topics: Cysteinyldopa; Dihydroxyphenylalanine; Humans; Isomerism; Japan; Lymphatic Metastasis; Melanoma; Ski | 1983 |
[A newly established melanoma cell line (GAK) with 5-S-cysteinyldopa phenotype].
Topics: Aged; Animals; Cell Line; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Isomerism; Lymphati | 1984 |
Imaging of a metastatic gastrointestinal carcinoid by F-18-DOPA positron emission tomography.
Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Fluorine Radioisotopes; Gastrointestinal Neoplasms; Humans; | 1999 |
Whole-body 18F dopa PET for detection of gastrointestinal carcinoid tumors.
Topics: Adult; Aged; Carcinoid Tumor; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluorodeoxyglu | 2001 |
5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis.
Topics: Adult; Aged; Cysteinyldopa; Dihydroxyphenylalanine; Female; Hair Color; Humans; Lymphatic Metastasis | 1979 |
Plasma 5-S-cysteinyldopa differentiates patients with primary and metastatic melanoma from patients with dysplastic nevus syndrome and normal subjects.
Topics: Adult; Aged; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Cysteinyldopa; Diagnosis, Diff | 1988 |
Fluorescent dopa reaction of nevi and melanomas.
Topics: Dihydroxyphenylalanine; Fluorescence; Humans; Lymphatic Metastasis; Melanoma; Microscopy, Fluorescen | 1966 |