dihydroxyphenylalanine has been researched along with Hypoxia in 41 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)." | 7.67 | The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986) |
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 7.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "We examined the effects of hypoxia (8% O2) on in vivo tyrosine hydroxylation, a rate-limiting step for catecholamine synthesis, in the rat adrenal gland." | 3.68 | Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions. ( Fujiwara, M; Hamahata, K; Hasegawa, H; Hayashi, Y; Koshimura, K; Lee, K; Miwa, S; Watanabe, Y, 1990) |
| "The effects of cinepazide, a vasodilator, on the content, biosynthesis and turnover of noradrenaline (NA), dopamine (DA) and 5-hydroxytryptamine (5-HT) in the rat brain were examined under room air and hypoxia (10% O2, 90% N2)." | 3.67 | The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. ( Fujiwara, M; Lee, K; Miwa, S, 1986) |
| " Using this method, we investigated the effects of immobilization stress, reserpine, and hypoxia on in vivo activities of tyrosine hydroxylase in the adrenal gland." | 3.67 | A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland. ( Fujiwara, M; Hamahata, K; Hayashi, Y; Kamel, A; Koshimura, K; Lee, K; Miwa, S, 1988) |
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 3.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (80.49) | 18.7374 |
| 1990's | 5 (12.20) | 18.2507 |
| 2000's | 2 (4.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, S | 1 |
| Li, X | 1 |
| Zhang, F | 1 |
| Mao, J | 1 |
| Cao, M | 1 |
| Zhang, X | 1 |
| Huang, S | 1 |
| Duan, X | 1 |
| Shen, J | 1 |
| GRAHAM, P | 1 |
| KAHLSON, G | 1 |
| ROSENGREN, E | 1 |
| Ivanov, AI | 1 |
| Khitrov, NK | 2 |
| Alaverdia, AM | 1 |
| Toloknov, AV | 1 |
| Tezikov, EB | 1 |
| Hedner, T | 4 |
| Lundborg, P | 4 |
| Gautier, H | 1 |
| Bonora, M | 1 |
| Claustre, J | 1 |
| Peyrin, L | 2 |
| Sakabe, T | 1 |
| Dahlgren, N | 1 |
| Carlsson, A | 8 |
| Siesjö, BK | 1 |
| Dalmaz, Y | 1 |
| Pequignot, JM | 1 |
| Cottet-Emard, JM | 1 |
| Tammela, O | 1 |
| Pastuszko, A | 1 |
| Lajevardi, NS | 1 |
| Delivoria-Papadopoulos, M | 1 |
| Wilson, DF | 1 |
| Serebrovskaya, TV | 2 |
| Karaban, IN | 2 |
| Kolesnikova, EE | 2 |
| Mishunina, TM | 2 |
| Kuzminskaya, LA | 2 |
| Serbrovsky, AN | 1 |
| Swanson, RJ | 2 |
| Bauer, R | 1 |
| Brust, P | 1 |
| Walter, B | 1 |
| Vorwieger, G | 1 |
| Bergmann, R | 1 |
| Füchtner, F | 1 |
| Steinbach, J | 1 |
| el-Hallag, E | 1 |
| Fritz, A | 1 |
| Johannsen, B | 1 |
| Zwiener, U | 1 |
| Beloshitsky, PV | 1 |
| Ilyin, VN | 1 |
| Krasuk, AN | 1 |
| Safronova, OS | 1 |
| Engel, J | 4 |
| Brown, RM | 3 |
| Kehr, W | 1 |
| Davis, JN | 3 |
| Lauweryns, JM | 1 |
| Cokelaere, M | 1 |
| Deleersynder, M | 1 |
| Liebens, M | 1 |
| Burke, RE | 1 |
| Reches, A | 1 |
| Hayashi, Y | 2 |
| Miwa, S | 4 |
| Lee, K | 3 |
| Koshimura, K | 2 |
| Hamahata, K | 2 |
| Hasegawa, H | 1 |
| Fujiwara, M | 6 |
| Watanabe, Y | 1 |
| Brokaw, JJ | 1 |
| Hansen, JT | 1 |
| Christie, DS | 1 |
| Inoue, M | 1 |
| Kamel, A | 1 |
| Rigual, R | 1 |
| Gonzalez, E | 1 |
| Gonzalez, C | 1 |
| Fidone, S | 1 |
| Brown, R | 2 |
| David, JN | 1 |
| Solov'ev, GM | 1 |
| Matlina, ESh | 1 |
| Cymerman, A | 1 |
| Robinson, SM | 1 |
| McCullough, D | 1 |
| Walsh, C | 1 |
| McLelland, J | 1 |
| Snider, SR | 2 |
| Lhermitte, F | 1 |
| Marteau, R | 1 |
| Degos, CF | 1 |
| Kassil', GN | 1 |
| Beleda, RV | 1 |
| Artamonov, NN | 1 |
| Zakharova, SI | 1 |
| Goncharenko, EN | 1 |
| Dzhanumova, T | 1 |
| Zhat'kova, GS | 1 |
| Kudriashov, IuB | 1 |
| Yates, RD | 1 |
| Chen, IL | 1 |
| Duncan, D | 1 |
| Mascorro, JA | 1 |
| Debijadji, R | 1 |
| Perović, L | 1 |
| Varagić, V | 1 |
| Stosić, N | 1 |
2 reviews available for dihydroxyphenylalanine and Hypoxia
| Article | Year |
|---|---|
Measurements of monoamine synthesis and turnover with special reference to 5-hydroxytryptamine.
Topics: Acetamides; Animals; Benserazide; Benzyl Compounds; Biogenic Amines; Brain; Carboxy-Lyases; Dibenzaz | 1974 |
[Cardiac catecholamines in stress situations].
Topics: Adrenal Glands; Animals; Brain Injuries; Burns; Catecholamines; Cold Temperature; Dihydroxyphenylala | 1973 |
1 trial available for dihydroxyphenylalanine and Hypoxia
| Article | Year |
|---|---|
Geriatric men at altitude: hypoxic ventilatory sensitivity and blood dopamine changes.
Topics: Adaptation, Physiological; Adult; Age Factors; Aging; Altitude; Analysis of Variance; Dihydroxypheny | 2000 |
38 other studies available for dihydroxyphenylalanine and Hypoxia
| Article | Year |
|---|---|
Manganese Dioxide-Based Nanocarrier Delivers Paclitaxel to Enhance Chemotherapy against Orthotopic Glioma through Hypoxia Relief.
Topics: Animals; Dihydroxyphenylalanine; Glioma; Hypoxia; Manganese Compounds; Oxides; Paclitaxel; Rats; Tum | 2022 |
HISTAMINE FORMATION IN PHYSICAL EXERCISE, ANOXIA AND UNDER THE INFLUENCE OF ADRENALINE AND RELATED SUBSTANCES.
Topics: Adrenal Medulla; Adrenalectomy; Altitude; Cortisone; Diaphragm; Dihydroxyphenylalanine; Dopamine; Ep | 1964 |
[Heart function and the mechanisms of its regulation in modelling adaptation to hypoxia by 2,4-dinitrophenol administration].
Topics: Adaptation, Physiological; Animals; Dihydroxyphenylalanine; Dinitrophenols; Disease Models, Animal; | 1983 |
[Trace processes in the circulatory system of rats during prolonged adaptation to hypoxia].
Topics: Adaptation, Physiological; Animals; Blood Pressure; Cardiomegaly; Dihydroxyphenylalanine; Heart; Hea | 1981 |
Catecholamine metabolism in neonatal rat brain during asphyxia and recovery.
Topics: Animals; Animals, Newborn; Asphyxia; Brain; Brain Stem; Catecholamines; Diencephalon; Dihydroxypheny | 1980 |
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; D | 1980 |
Free and conjugated catecholamines and metabolites in cat urine after hypoxia.
Topics: Adrenal Medulla; Animals; Catecholamines; Cats; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hypox | 1982 |
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyph | 1982 |
Adrenal response to long-term hypoxia is still increased after carotid body denervation in rat.
Topics: Adrenal Glands; alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carotid | 1994 |
Activity of tyrosine hydroxylase in the striatum of newborn piglets in response to hypocapnic hypoxia.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Cerebral Cortex; Corpus Striatum; Dialysis; Dihydroxyphen | 1993 |
Human hypoxic ventilatory response with blood dopamine content under intermittent hypoxic training.
Topics: Adaptation, Physiological; Adult; Breath Tests; Breathing Exercises; Dihydroxyphenylalanine; Dopamin | 1999 |
Relation between brain tissue pO2 and dopamine synthesis of basal ganglia--a 18FDOPA-PET study in newborn piglets.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Basal Ganglia; Blood Pressure; Brain; Dihydroxypheny | 2000 |
Effect of hypoxia on monoamine synthesis in brains of developing rats.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Benzyl Compounds; Brain; Carboxy-Lyases; Dihydroxyph | 1977 |
Effect of hypoxia on monoamine synthesis in brains of developing rats. II. Different length of exposure.
Topics: Animals; Brain; Dihydroxyphenylalanine; Hypoxia; Rats; Serotonin; Time Factors; Tryptophan; Tryptoph | 1977 |
Effect of hypoxia on monoamine synthesis in brains of developing rats. III. Various O2 levels.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Female; Hypoxia; Nore | 1978 |
Functional and biochemical aspects of catecholamine metabolism in brain under hypoxia.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Brain; Catecholamin | 1975 |
Adaptation of brain monoamine synthesis to hypoxia in the rat.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Brain Chemistry; Chromatography, Ion Exchange; | 1975 |
Intrapulmonary neuro-epithelial bodies in newborn rabbits. Influence of hypoxia, hyperoxia, hypercapnia, nicotine, reserpine, L-DOPA and 5-HTP.
Topics: Animals; Chemoreceptor Cells; Dihydroxyphenylalanine; Exocytosis; Hypercapnia; Hypoxia; Lung; Micros | 1977 |
Preserved striatal tyrosine hydroxylase activity, assessed in vivo, following neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; B | 1991 |
Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions.
Topics: Adrenal Glands; Animals; Biopterins; Brain; Denervation; Dihydroxyphenylalanine; Hypoxia; Kinetics; | 1990 |
The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Hyd | 1986 |
The effects of hypoxia on catecholamine dynamics in the rat carotid body.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotid Body; Catecholamines; Dihydroxyphenylalanine; Dopam | 1985 |
Effects of hypoxia on the activities of noradrenergic and dopaminergic neurons in the rat brain.
Topics: alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenyla | 1986 |
A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland.
Topics: Adrenal Glands; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dihydro | 1988 |
Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation.
Topics: Animals; Carotid Body; Carotid Sinus; Catecholamines; Cats; Dihydroxyphenylalanine; Dopamine; Electr | 1986 |
Dopa reversal of hypoxia-induced disruption of the conditioned avoidance response.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atmosphere; Avoidance Learning; Brain; Dihydr | 1973 |
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; | 1973 |
Evidence for catecholamine involvement in the suppression of locomotor activity due to hypoxia.
Topics: Amphetamine; Animals; Apomorphine; Clonidine; Dihydroxyphenylalanine; Female; Hypoxia; Mice; Motor A | 1973 |
Alteration of rat brain catecholamine metabolism during exposure to hypobaric hypoxia.
Topics: Altitude; Animals; Brain; Brain Chemistry; Catecholamines; Chromatography, Ion Exchange; Dihydroxyph | 1972 |
Granular "endocrine" cells in avian respiratory epithelia.
Topics: Animals; Animals, Newborn; Axons; Bronchi; Chick Embryo; Chickens; Cytoplasmic Granules; Dihydroxyph | 1974 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. I. The adrenal medulla.
Topics: Adrenal Medulla; Animals; Dihydroxyphenylalanine; Dopamine; Electroshock; Epinephrine; Humans; Hyper | 1974 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. II. The central nervous system.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Depression, Chemi | 1974 |
[Pharmacologic analysis of a new case of postanoxic intention and action myoclonus].
Topics: Adult; Anesthesia, General; Butyrophenones; Catecholamines; Coma; Dihydroxyphenylalanine; Endoscopy; | 1972 |
Effect of hypoxia on tyrosine and tryptophan hydroxylation in unanaesthetized rat brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Dihydroxyphenylalanin | 1973 |
[Prediction of autonomic reactions during extreme actions on the body].
Topics: 17-Hydroxycorticosteroids; Altitude; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; | 1972 |
[Role of endogenous dopamine in the radiation-protective effect of radioprotectors].
Topics: Adrenal Glands; Animals; Cysteamine; Dihydroxyphenylalanine; Dopamine; Hypoxia; Intestine, Small; Li | 1972 |
The mechanism of storage and release of catecholamines from chromaffin cells.
Topics: Animals; Carotid Body; Catecholamines; Chromaffin System; Cytoplasmic Granules; Dihydroxyphenylalani | 1971 |
Effect of hypoxic hypoxia on the catecholamine content and some cytochemical changes in the hypothalamus of the cat.
Topics: Aerospace Medicine; Altitude; Animals; Atmospheric Pressure; Catecholamines; Cats; Dihydroxyphenylal | 1969 |