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dihydroxyphenylalanine and Hypothermia

dihydroxyphenylalanine has been researched along with Hypothermia in 12 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
" In vivo, NAE-086 induced all the typical effects of a 5-HT(1A) receptor agonist in rats: it decreased 5-HT synthesis (5-HTP accumulation) and 5-HT turnover (measured as the ratio of 5-hydroxyindoleacetic acid/5-HT), increased corticosterone secretion, induced the 5-HT(1A) syndrome (flat body posture and forepaw treading), inhibited the cage-leaving response, and caused hypothermia."3.71The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. ( Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Rënyi, L; Ross, SB; Sällemark, M, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GRIESEMER, EC1
GASNER, LT1
CLARK, WG1
ASKEW, BM1
NAKAJIMA, H1
GRANDJEAN, JL1
LHUILLIER, J1
THUILLIER, J1
Rënyi, L1
Evenden, JL1
Fowler, CJ1
Jerning, E1
Kelder, D1
Lake-Bakaar, D1
Larsson, LG1
Mohell, N1
Sällemark, M1
Ross, SB1
Okuda, C1
Saito, A1
Miyazaki, M1
Kuriyama, K1
Spinks, A1
Whittle, BA1
Menon, MK1
Dandiya, PC1
Yehuda, S1
Wurtman, RJ1
Cooper, F1
Leonard, BE1
Schnieden, H1
Gaetani, M1
Debeus, R1
Lotti, VJ1
Porter, CC1
Oehme, P1
Schwarz, K1

Other Studies

12 other studies available for dihydroxyphenylalanine and Hypothermia

ArticleYear
Antagonism of reserpine hypothermia in mice by 3,4-dihydroxyphenylalanine (dopa).
    Proceedings of the Western Pharmacology Society, 1962, Volume: 5

    Topics: Animals; Dihydroxyphenylalanine; Hostility; Hypothermia; Hypothermia, Induced; Mice; Reserpine

1962
A SIMPLE SCREENING PROCEDURE FOR IMIPRAMINE-LIKE ANTIDEPRESSANT AGENTS.
    Life sciences (1962), 1963, Volume: 10

    Topics: 5-Hydroxytryptophan; Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Atropine; Beme

1963
[EXPERIMENTAL ANTAGONISM OF CHLORPROMAZINE AND THIORIDAZINE IN RELATION TO CERTAIN EFFECTS OF LYSERGIDE].
    L'Encephale, 1964, Volume: 53

    Topics: 5-Hydroxytryptophan; Catalepsy; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hypothermia; Lysergi

1964
The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Benzopyrans; Corticosterone; Cyclic AMP; Dihydroxyph

2001
Alteration of the turnover of dopamine and 5-hydroxytryptamine in rat brain associated with hypothermia.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Corticosterone; Dihydroxyphenylalan

1986
The pharmacology of actomol and related compounds.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:1

    Topics: Animals; Behavior, Animal; Dihydroxyphenylalanine; Hydrazines; Hypothermia; Mice; Monoamine Oxidase

1966
Mechanism of the protective effect of reserpine on aggregated mice treated with (+)-amphetamine.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:9

    Topics: Animals; Brain Chemistry; Dextroamphetamine; Dihydroxyphenylalanine; Hypothermia; Methyltyrosines; M

1967
Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine.
    Nature, 1972, Dec-22, Volume: 240, Issue:5382

    Topics: Animals; Apomorphine; Brain Chemistry; Clonidine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamin

1972
The role of catecholamines in the reversal of reserpine-induced hypothermia in mice by desipramine and chlorpromazine.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Body Temperature; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Dose

1972
Action of L-dopa, norepinephrine and amantadine on ulcers caused by reserpine in the rat.
    Digestion, 1972, Volume: 7, Issue:5

    Topics: Administration, Oral; Amantadine; Animals; Dihydroxyphenylalanine; Dose-Response Relationship, Drug;

1972
Potentiation and inhbition of some central actions of L(-)-dopa by decarboxylase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Blepharoptosis; Brain; Brai

1970
[Etiology and therapy of Parkinson's syndrome and related pharmacological concepts shown in experimental models].
    Das Deutsche Gesundheitswesen, 1966, Apr-28, Volume: 21, Issue:17

    Topics: Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Humans; Hypothermia; Mic

1966