dihydroxyphenylalanine has been researched along with Hypercapnia in 10 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 7.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "The effects of induced hypo- and hypercapnia upon the rate of hydroxylation of tryptophan and tyrosine in the rat brain were studied by measuring the accumulation of 5-HTP and DOPA following administration of the aromatic L-aminoacid decarboxylase inhibitor 3-hydroxybenzylhydrazine HCl (NSD 1015)." | 7.65 | Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain. ( Carlsson, A; Holmin, T; Lindqvist, M; Siesjö, BK, 1977) |
| " Monoamine synthesis in whole brain was measured during, and at various intervals after, hypercapnia by estimating the accumulation of dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) after inhibition of aromatic L-amino-acid decarboxylase with NSD 1015." | 3.66 | Monoamine synthesis and concentration in neonatal rat brain during hypercapnia and recovery. ( Hedner, T; Lundborg, P, 1982) |
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 3.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "The effects of induced hypo- and hypercapnia upon the rate of hydroxylation of tryptophan and tyrosine in the rat brain were studied by measuring the accumulation of 5-HTP and DOPA following administration of the aromatic L-aminoacid decarboxylase inhibitor 3-hydroxybenzylhydrazine HCl (NSD 1015)." | 3.65 | Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain. ( Carlsson, A; Holmin, T; Lindqvist, M; Siesjö, BK, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedner, T | 1 |
| Lundborg, P | 1 |
| Gautier, H | 1 |
| Bonora, M | 1 |
| Sakabe, T | 1 |
| Dahlgren, N | 1 |
| Carlsson, A | 4 |
| Siesjö, BK | 2 |
| Bauer, R | 2 |
| Brust, P | 2 |
| Walter, B | 2 |
| Vorwieger, G | 2 |
| Bergmann, R | 2 |
| Füchtner, F | 2 |
| Steinbach, J | 2 |
| el-Hallag, E | 1 |
| Fritz, A | 2 |
| Johannsen, B | 2 |
| Zwiener, U | 2 |
| Elhalag, E | 1 |
| Hinz, R | 1 |
| Holmin, T | 1 |
| Lindqvist, M | 1 |
| Lauweryns, JM | 1 |
| Cokelaere, M | 1 |
| Deleersynder, M | 1 |
| Liebens, M | 1 |
| Snider, SR | 2 |
| Brown, RM | 2 |
| Nahas, GG | 1 |
| Steinsland, OS | 1 |
10 other studies available for dihydroxyphenylalanine and Hypercapnia
| Article | Year |
|---|---|
Monoamine synthesis and concentration in neonatal rat brain during hypercapnia and recovery.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; | 1982 |
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; D | 1980 |
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyph | 1982 |
Relation between brain tissue pO2 and dopamine synthesis of basal ganglia--a 18FDOPA-PET study in newborn piglets.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Basal Ganglia; Blood Pressure; Brain; Dihydroxypheny | 2000 |
Effect of hypoxia/hypercapnia on metabolism of 6-[(18)F]fluoro-L-DOPA in newborn piglets.
Topics: Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Asphyxia Neonatorum; Brain; Cardiov | 2002 |
Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Brain; Carbohydrate Metabolism; Carbon Dioxide; | 1977 |
Intrapulmonary neuro-epithelial bodies in newborn rabbits. Influence of hypoxia, hyperoxia, hypercapnia, nicotine, reserpine, L-DOPA and 5-HTP.
Topics: Animals; Chemoreceptor Cells; Dihydroxyphenylalanine; Exocytosis; Hypercapnia; Hypoxia; Lung; Micros | 1977 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. I. The adrenal medulla.
Topics: Adrenal Medulla; Animals; Dihydroxyphenylalanine; Dopamine; Electroshock; Epinephrine; Humans; Hyper | 1974 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. II. The central nervous system.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Depression, Chemi | 1974 |
Increased rate of catecholamine synthesis during respiratory acidosis.
Topics: Acidosis, Respiratory; Adrenal Glands; Animals; Brain Chemistry; Catecholamines; Dihydroxyphenylalan | 1968 |