dihydroxyphenylalanine has been researched along with Hyperactivity, Motor in 42 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Either L-dopa, in combination with 1-alpha-methyldopa hydrazine (MK-486), or 1-(2''-pyrimidyl)-4-piperonylpiperazine, an agent that stimulates dopamine receptors, relieves surgically induced tremor in monkeys and concomitantly evokes involuntary movements." | 3.65 | Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent. ( Anagnoste, B; Battista, AF; Fuxe, K; Goldstein, M; Ohmoto, T, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (97.62) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bello, EP | 1 |
| Mateo, Y | 1 |
| Gelman, DM | 1 |
| Noaín, D | 1 |
| Shin, JH | 1 |
| Low, MJ | 1 |
| Alvarez, VA | 1 |
| Lovinger, DM | 1 |
| Rubinstein, M | 1 |
| Wöller, W | 1 |
| Tegeler, J | 1 |
| Magalov, ShI | 1 |
| Dadali, EL | 1 |
| Shoulson, I | 1 |
| Glaubiger, GA | 1 |
| Chase, TN | 1 |
| Van Sande, M | 1 |
| Caers, J | 1 |
| Lowenthal, A | 1 |
| Birket-Smith, E | 1 |
| Andersen, JV | 1 |
| Dalén, P | 1 |
| Steg, G | 1 |
| Antonini, F | 1 |
| Baroni, A | 1 |
| Bucalossi, A | 1 |
| Roveyaz, L | 1 |
| Soyka, D | 1 |
| Sassin, JF | 1 |
| Taub, S | 1 |
| Weitzman, ED | 1 |
| Re', O | 1 |
| Arushanian, EB | 1 |
| Wender, PH | 1 |
| Wälzholz, U | 1 |
| Bechtereva, NP | 1 |
| Bondartchuk, AN | 1 |
| Gretchin, VB | 1 |
| Iliukhina, VA | 1 |
| Kambarova, DK | 1 |
| Matveev, YK | 1 |
| Petushkov, EP | 1 |
| Pozdeev, VK | 1 |
| Smirnov, VM | 1 |
| Shandurina, AN | 1 |
| Goldstein, M | 1 |
| Battista, AF | 1 |
| Ohmoto, T | 1 |
| Anagnoste, B | 1 |
| Fuxe, K | 1 |
| Wodak, J | 1 |
| Gilligan, BS | 1 |
| Veale, JL | 1 |
| Dowty, BJ | 1 |
| Groneberg, P | 1 |
| Struppler, A | 1 |
| Tkachev, RA | 1 |
| Markova, ED | 1 |
| Gotovtseva, EV | 1 |
| Barkhatova, VP | 1 |
| Ivanova-Smolenskaia, IA | 1 |
| Mrochek, JE | 1 |
| Dinsmore, SR | 1 |
| Ohrt, DW | 1 |
| Fischer, PA | 1 |
| Schneider, E | 1 |
| Jacobi, P | 1 |
| Maxion, H | 1 |
| Mel'nichuk, PV | 1 |
| Sosnovskaia, LS | 1 |
| Fujieda, T | 1 |
| Yamauchi, T | 1 |
| Takahashi, S | 1 |
| Moroji, T | 1 |
| Knutsson, E | 1 |
| Mårtensson, A | 1 |
| Randrup, A | 1 |
| Munkvad, I | 1 |
| Kaeser, HE | 1 |
| Ferel, D | 1 |
| Wurmser, P | 1 |
| Diemath, HE | 1 |
| Enge, S | 1 |
| Lechner, H | 1 |
| Scheckel, CL | 1 |
| Boff, E | 1 |
| Pazery, LM | 1 |
| Mettler, FA | 1 |
| Barbeau, A | 1 |
| Goodwin, FK | 1 |
| Görlich, J | 1 |
| Markus, E | 1 |
| Cools, AR | 1 |
| Reveno, WS | 1 |
| Bauer, RB | 1 |
| Rosenbaum, H | 1 |
| Fog, R | 1 |
| Pakkenberg, H | 1 |
| Metzel, E | 1 |
| Riechert, T | 1 |
| Stracke, D | 1 |
| Barrett, RE | 1 |
| Yahr, MD | 1 |
| Duvoisin, RC | 1 |
| Strömberg, U | 1 |
| Hippius, H | 1 |
| Logemann, G | 1 |
| Eichhorn, F | 1 |
| Rutenberg, A | 1 |
| Kott, E | 1 |
4 reviews available for dihydroxyphenylalanine and Hyperactivity, Motor
| Article | Year |
|---|---|
2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action.
Topics: Acetylcholine; Blood-Brain Barrier; Brain Chemistry; Carbon Radioisotopes; Child; Choline; Deanol; D | 1974 |
[The role of dopamine in the physiology and pathology of the basal ganglia].
Topics: Basal Ganglia; Brain; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopa | 1972 |
Pharmacological studies on the brain mechanisms underlying two forms of behavioral excitation: stereotyped hyperactivity and "rage".
Topics: Aggression; Amphetamine; Anger; Animals; Basal Ganglia; Behavior, Animal; Brain; Brain Chemistry; Di | 1969 |
Psychiatric side effects of levodopa in man.
Topics: Animals; Brain; Catecholamines; Cognition Disorders; Delirium; Depression; Dihydroxyphenylalanine; D | 1971 |
2 trials available for dihydroxyphenylalanine and Hyperactivity, Motor
| Article | Year |
|---|---|
[Management of Parkinson's syndrome using levadopa. Results of a long-term study].
Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Clinical Trials as Topic; Depression; Dihyd | 1972 |
[L-dopa therapy of Parkinson's syndrome. Comparison of pure L-dopa and the combination preparation L-dopa and decarboxylase inhibitor].
Topics: Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Female; Humans; Hyperkinesis; Male; Middl | 1972 |
36 other studies available for dihydroxyphenylalanine and Hyperactivity, Motor
| Article | Year |
|---|---|
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
Topics: Analysis of Variance; Animals; Autoradiography; Baclofen; Choice Behavior; Cocaine; Conditioning, Op | 2011 |
[Tardive dyskinesia: clinical picture, prevalence, and pathophysiology].
Topics: Age Factors; Antipsychotic Agents; Diagnosis, Differential; Dihydroxyphenylalanine; Dyskinesia, Drug | 1983 |
[Catecholamine metabolism in Huntington's chorea (in patients and their phenotypically healthy relatives)].
Topics: Adolescent; Adult; Aged; Catecholamines; Child; Dihydroxyphenylalanine; Dopamine; Epinephrine; Femal | 1980 |
On-off response. Clinical and biochemical correlations during oral and intravenous levodopa administration in parkinsonian patients.
Topics: Administration, Oral; Aged; Blood Pressure; Dihydroxyphenylalanine; Dose-Response Relationship, Drug | 1975 |
Cerebrospinal fluid amino acids in extrapyramidal disorders before and after L-DOPA treatment.
Topics: Adult; Aged; Amino Acids; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Chromatography, Ion Exc | 1971 |
Treatment of side-effects of levodopa.
Topics: Dihydroxyphenylalanine; Disulfiram; Humans; Hyperkinesis; Hypertension; Parkinson Disease | 1973 |
Lithium and levodopa in parkinsonism.
Topics: Dihydroxyphenylalanine; Female; Humans; Hyperkinesis; Lithium; Male; Parkinson Disease | 1973 |
[Study of L-dopa treatment and its principal side effects in aged subjects].
Topics: Aged; Antidepressive Agents; Asthenia; Cardiovascular Diseases; Circadian Rhythm; Dihydroxyphenylala | 1972 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |
Editorial: Facial hyperkinesis.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Facial Muscles; Haplorhini; Humans; Hyperkinesis; Phenoth | 1974 |
Hyperkinesia and changes in behavior produced in normal monkeys by L-dopa.
Topics: Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Fe | 1972 |
The minimal brain dysfunction syndrome in children. I. The syndrome and its relevance for psychiatry. II. A psychological and biochemical model for the syndrome.
Topics: Affect; Amphetamine; Arousal; Attention Deficit Disorder with Hyperactivity; Autonomic Nervous Syste | 1972 |
Structural-functional organization of the human brain and the pathophysiology of the Parkinsonian type hyperkineses.
Topics: Brain; Brain Stem; Caudate Nucleus; Dihydroxyphenylalanine; Electroencephalography; Evoked Potential | 1972 |
Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Dihydroxyphenylalanine; Dioxoles; Drug Interactions; | 1973 |
Review of 12 months' treatment with L-dopa in Parkinson's disease, with remarks on unusual side effects.
Topics: Adult; Aged; Atrial Flutter; Body Weight; Deglutition Disorders; Diazepam; Dihydroxyphenylalanine; D | 1972 |
[The therapeutic effect of L-dopa].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Asthma; Brain; Dihydroxyphenylalanine; Dopamine; Human | 1972 |
[Principles of the pathogenetic therapy of congenital extrapyramidal diseases].
Topics: Adolescent; Adult; Atropine; Basal Ganglia Diseases; Chelating Agents; Chronic Disease; Dihydroxyphe | 1973 |
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chroma | 1973 |
[Combination therapy of Parkinson's syndrome using L-dopa and a decarboxylase inhibitor].
Topics: Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Combinations; Female; Humans; Hyperkinesis; Male; | 1973 |
[L-DOPA therapy of deforming muscular dystonia in children].
Topics: Adolescent; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Female; Humans; Hyperkines | 1973 |
Letter: Effect of levodopa on tremor in Benedikt's syndrome.
Topics: Adult; Ataxia; Dihydroxyphenylalanine; Humans; Hyperkinesis; Male; Mesencephalon; Ophthalmoplegia; P | 1974 |
Improvement in mono-manual dexterity in parkinsonism when supplementing levodopa with an extracerebral decarboxylase inhibitor, RO 4-4602.
Topics: Administration, Oral; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Do | 1974 |
[Treatment of Parkinson's syndrome with L-dopa].
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antihypertensive Agents; Barbiturates; | 1970 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir | 1970 |
Hyperactive states related to the metabolism of norepinephrine and similar biochemicals.
Topics: Animals; Avoidance Learning; Behavior, Animal; Brain; Brain Chemistry; Carboxy-Lyases; Catecholamine | 1969 |
Nigrofugal connections in the primate brain.
Topics: Animals; Brain; Cerebral Decortication; Dihydroxyphenylalanine; Globus Pallidus; Haplorhini; Humans; | 1970 |
Rationale for the use of L-dopa in the torsion dystonias.
Topics: Animals; Basal Ganglia; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Haplorhini; | 1970 |
Athetoid and choreiform hyperkinesias produced by caudate application of dopamine in cats.
Topics: Animals; Athetosis; Behavior, Animal; Cats; Caudate Nucleus; Chorea; Dextroamphetamine; Dihydroxyphe | 1972 |
L-dopa treatment of parkinsonism. Clinical observations on the use of amantadine hydrochloride.
Topics: Aged; Amantadine; Chlorides; Depression; Dihydroxyphenylalanine; Drug Hypersensitivity; Female; Foll | 1971 |
Intracerebral lesions causing stereotyped behaviour in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Behavior, Animal; Brain Injuries; Catalepsy; Catheterization; D | 1971 |
Enzymes of dopa metabolism of diencephalic structures in man and rabbit with special regard to extrapyramidal disorders.
Topics: Animals; Brain Stem; Diencephalon; Dihydroxyphenylalanine; Dopa Decarboxylase; Humans; Hyperkinesis; | 1970 |
Torsion dystonia and spasmodic torticollis--results of treatment with L-dopa.
Topics: Acute Disease; Adolescent; Adult; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Fema | 1970 |
DOPA effects on motility in mice; potentiation by MK 485 and dexchlorpheniramine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Brain; Chlorpheniramine; | 1970 |
[Effect of dioxyphenylalanine (L-DOPA) on extrapyramidal motoric hyperkineses after prolonged neuroleptic therapy].
Topics: Depression, Chemical; Dihydroxyphenylalanine; Drive; Emotions; Extrapyramidal Tracts; Female; Humans | 1970 |
Fluorometric method for quantitatively estimating urinary dihydroxyphenylethylamine (dopamine), dihydroxyphenylalanine (dopa), and dihydroxyphenylacetic acid (dopac).
Topics: Aluminum; Bone Neoplasms; Dihydroxyphenylalanine; Dopamine; Electrophoresis; Ethylenediamines; Fluor | 1971 |
Differentiation of tardive dyskinesias and drug-induced Parkinsonism.
Topics: Amantadine; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Hyperkinesis; Movement Disorder | 1971 |