Page last updated: 2024-10-18

dihydroxyphenylalanine and Genetic Predisposition

dihydroxyphenylalanine has been researched along with Genetic Predisposition in 17 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
"With respect to Parkinson's disease PET and later SPECT allowed the number of dopaminergic neurons to be assessed in vivo."2.46[Nuclear medicine imaging in patients with Parkinson's syndrome: an update]. ( Schwarz, J, 2010)
"Many different disorders have dystonia as the only or primary sign."2.40Dystonia. ( Bressman, SB, 1998)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's10 (58.82)29.6817
2010's4 (23.53)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Lopez, G2
Eisenberg, DP1
Gregory, MD1
Ianni, AM1
Grogans, SE1
Masdeu, JC1
Kim, J1
Groden, C1
Sidransky, E1
Berman, KF2
Dahoun, T2
Pardiñas, AF2
Veronese, M2
Bloomfield, MAP2
Jauhar, S2
Bonoldi, I2
Froudist-Walsh, S2
Nosarti, C1
Korth, C1
Hennah, W1
Walters, J1
Prata, D1
Howes, OD2
D'Ambrosio, E1
Rogdaki, M1
Walters, JTR1
July, M1
Santhanam, P1
Giovanella, L1
Treglia, G1
Schwarz, J1
Ruprecht-Dörfler, P1
Berg, D1
Tucha, O1
Benz, P1
Meier-Meitinger, M1
Alders, GL1
Lange, KW1
Becker, G1
Hernandez, DG1
Paisán-Ruíz, C1
McInerney-Leo, A1
Jain, S1
Meyer-Lindenberg, A1
Evans, EW1
Johnson, J1
Auburger, G1
Schäffer, AA1
Lopez, GJ1
Nussbaum, RL1
Singleton, AB1
Hagenah, J2
Saunders-Pullman, R1
Hedrich, K2
Kabakci, K1
Habermann, K1
Wiegers, K1
Mohrmann, K1
Lohnau, T1
Raymond, D1
Vieregge, P1
Nygaard, T1
Ozelius, LJ1
Bressman, SB2
Klein, C2
Ros, R1
Thobois, S2
Streichenberger, N1
Kopp, N1
Sánchez, MP1
Pérez, M1
Hoenicka, J1
Avila, J1
Honnorat, J1
de Yébenes, JG2
Racette, BA1
Good, L1
Antenor, JA1
McGee-Minnich, L1
Moerlein, SM1
Videen, TO1
Perlmutter, JS1
Tai, YF1
Ahsan, RL1
Pavese, N1
Brooks, DJ2
Piccini, P2
Goldstein, DS1
Imrich, R1
Peckham, E1
Holmes, C1
Crews, C1
Hardy, J1
Singleton, A1
Hallett, M1
Binkofski, F1
Reetz, K1
Gaser, C1
Hilker, R1
van Eimeren, T1
Thiel, A1
Büchel, C1
Pramstaller, PP1
Siebner, HR1
Anokhina, IP1
Vertinskaia, AG1
Vekshina, NL1
Nebarakova, TP1
Ovchinnikov, IV1
Druzhina, EV1
Ovchinnikova, OI1
de Yebenez, J1
Lees, AJ1
Ceravolo, R1
Turjanski, N1
Pramstaller, P1
Guillouet, S1
Broussolle, E1

Reviews

4 reviews available for dihydroxyphenylalanine and Genetic Predisposition

ArticleYear
Role of positron emission tomography imaging in Multiple Endocrine Neoplasia syndromes.
    Clinical physiology and functional imaging, 2018, Volume: 38, Issue:1

    Topics: 5-Hydroxytryptophan; Biomarkers, Tumor; Dihydroxyphenylalanine; Ephedrine; Fluorodeoxyglucose F18; G

2018
[Nuclear medicine imaging in patients with Parkinson's syndrome: an update].
    Der Nervenarzt, 2010, Volume: 81, Issue:10

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Progression; Dopamine; Energy Metabolism; Fluorodeox

2010
Dystonia.
    Current opinion in neurology, 1998, Volume: 11, Issue:4

    Topics: Age of Onset; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Dystonia Musculorum Deformans; Gene

1998
Contributions of PET and SPECT to the understanding of the pathophysiology of Parkinson's disease.
    Neurophysiologie clinique = Clinical neurophysiology, 2001, Volume: 31, Issue:5

    Topics: Aging; Animals; Antiparkinson Agents; Basal Ganglia; Brain Tissue Transplantation; Cell Transplantat

2001

Other Studies

13 other studies available for dihydroxyphenylalanine and Genetic Predisposition

ArticleYear
Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations.
    Annals of neurology, 2020, Volume: 87, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Dihydroxyphenylalanine; Dopamine; Female; Gaucher Disease; Geneti

2020
The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study.
    Human molecular genetics, 2018, 10-15, Volume: 27, Issue:20

    Topics: Adult; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Genetic Predisposition to Disease;

2018
The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study.
    Psychiatry research. Neuroimaging, 2019, 09-30, Volume: 291

    Topics: Adult; Chromosomes, Human, Pair 10; Corpus Striatum; Cytoskeletal Proteins; Dihydroxyphenylalanine;

2019
Echogenicity of the substantia nigra in relatives of patients with sporadic Parkinson's disease.
    NeuroImage, 2003, Volume: 18, Issue:2

    Topics: Adult; Dihydroxyphenylalanine; Dominance, Cerebral; Female; Fluorine Radioisotopes; Genetic Predispo

2003
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.
    Annals of neurology, 2005, Volume: 57, Issue:3

    Topics: Aged; Amino Acid Sequence; Animals; Dihydroxyphenylalanine; DNA Mutational Analysis; Family Health;

2005
High mutation rate in dopa-responsive dystonia: detection with comprehensive GCHI screening.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Age Factors; Age of Onset; Brain; Dihydroxyphenylalanine; DNA Mutational Analysis

2005
A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy.
    Archives of neurology, 2005, Volume: 62, Issue:9

    Topics: Amino Acid Substitution; Blotting, Northern; Blotting, Western; Brain; Dihydroxyphenylalanine; DNA M

2005
[18F]FDOPA PET as an endophenotype for Parkinson's Disease linkage studies.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2006, Apr-05, Volume: 141B, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Consanguinity; Dihydroxyphenylalanine; Ethnicity; Family Health; Fem

2006
Characterization of dopaminergic dysfunction in familial progressive supranuclear palsy: an 18F-dopa PET study.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:3

    Topics: Aged; Amygdala; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Disease Progression; Dopam

2007
Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation.
    Neurology, 2007, Oct-16, Volume: 69, Issue:16

    Topics: Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Baroreflex; Dihydroxyphenylalanine; DNA Mut

2007
Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia.
    Neurology, 2007, Aug-28, Volume: 69, Issue:9

    Topics: Adult; Basal Ganglia Diseases; Corpus Striatum; Dihydroxyphenylalanine; DNA Mutational Analysis; Dop

2007
[Hereditary alcoholism: some neurochemical and genetic mechanisms].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1999, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Alleles; Brain; Dihydroxyphenylalanine; DNA; Genetic Dis

1999
Familial progressive supranuclear palsy: detection of subclinical cases using 18F-dopa and 18fluorodeoxyglucose positron emission tomography.
    Archives of neurology, 2001, Volume: 58, Issue:11

    Topics: Adult; Aged; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine Agents; Female; Fluorine Radioisotope

2001