dihydroxyphenylalanine has been researched along with Gaucher Disease in 2 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, G | 1 |
| Eisenberg, DP | 1 |
| Gregory, MD | 1 |
| Ianni, AM | 1 |
| Grogans, SE | 1 |
| Masdeu, JC | 1 |
| Kim, J | 1 |
| Groden, C | 1 |
| Sidransky, E | 1 |
| Berman, KF | 1 |
| Saunders-Pullman, R | 1 |
| Hagenah, J | 1 |
| Dhawan, V | 1 |
| Stanley, K | 1 |
| Pastores, G | 1 |
| Sathe, S | 1 |
| Tagliati, M | 1 |
| Condefer, K | 1 |
| Palmese, C | 1 |
| Brüggemann, N | 1 |
| Klein, C | 1 |
| Roe, A | 1 |
| Kornreich, R | 1 |
| Ozelius, L | 1 |
| Bressman, S | 1 |
2 other studies available for dihydroxyphenylalanine and Gaucher Disease
| Article | Year |
|---|---|
Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations.
Topics: Adult; Aged; Case-Control Studies; Dihydroxyphenylalanine; Dopamine; Female; Gaucher Disease; Geneti | 2020 |
Gaucher disease ascertained through a Parkinson's center: imaging and clinical characterization.
Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Gaucher Disease; Glucosylcerami | 2010 |