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dihydroxyphenylalanine and Focal Neurologic Deficits

dihydroxyphenylalanine has been researched along with Focal Neurologic Deficits in 19 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
" Hence we would advise that if for any reason anticholinergic drugs are to be withdrawn in patients receiving a stable dosage of levodopa this must be done slowly."2.64Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs. ( Hughes, RC; Polgar, JG; Walton, JN; Weightman, D, 1971)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199019 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klawans, HC1
Paulson, GW1
Barbeau, A2
Cotzias, GC3
Papavasiliou, PS3
Gellene, R1
Cook, DG1
Fahn, S1
Brait, KA1
Schenker, S1
Breen, KJ1
Hoyumpa, AM1
Potvin, AR1
Albers, JW1
Repa, BS1
Henderson, WG1
Walker, JE1
Stribley, RF1
Tourtellotte, WW1
Mahoudeau, D1
Singer, B1
Gilbert, JC1
Goulon, M1
Gajdos, P1
Girard, PF1
Trillet, M1
Kopp, N1
Fehling, C1
Kaufman, B1
Mena, I2
Rosenstock, HA1
Simons, DG1
Meyer, JS1
McLennan, JE1
Nakano, K1
Tyler, HR1
Schwab, RS1
Jameson, HD1
González-Posada, J1
Hernández-Peniche, J1
Tirado-Arroyave, S1
Ikeda, H1
Baba, O1
Ishino, H1
Mars, H1
Gillo-Joffroy, L1
Court, J1
Fuenzalida, S1
McPherson, A1
Weintraub, MI1
Van Woert, MH1
Hughes, RC1
Polgar, JG1
Weightman, D1
Walton, JN1
Refsum, S1

Reviews

2 reviews available for dihydroxyphenylalanine and Focal Neurologic Deficits

ArticleYear
Hepatic encephalopathy: current status.
    Gastroenterology, 1974, Volume: 66, Issue:1

    Topics: Adrenal Cortex Hormones; Amino Acids; Ammonia; Animals; Anti-Bacterial Agents; Biogenic Amines; Dihy

1974
Quantitative evaluation of neuropharmacological trials.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:3

    Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin

1974

Trials

5 trials available for dihydroxyphenylalanine and Focal Neurologic Deficits

ArticleYear
Modification of Parkinsonism--chronic treatment with L-dopa.
    The New England journal of medicine, 1969, Feb-13, Volume: 280, Issue:7

    Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blo

1969
Quantitative evaluation of neuropharmacological trials.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:3

    Topics: Activities of Daily Living; Age Factors; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanin

1974
Similarities between neurologic effects of L-dopa and of apomorphine.
    The New England journal of medicine, 1970, 01-01, Volume: 282, Issue:1

    Topics: Adult; Apomorphine; Brain; Child; Clinical Trials as Topic; Cyanides; Dihydroxyphenylalanine; Female

1970
Modification of chronic manganese poisoning. Treatment with L-dopa or 5-OH tryptophane.
    The New England journal of medicine, 1970, Jan-01, Volume: 282, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Chronic Disease; Dihydroxyphenylalanine; Humans; Male; Manga

1970
Levodopa in Parkinsonism: the effects of withdrawal of anticholinergic drugs.
    British medical journal, 1971, May-29, Volume: 2, Issue:5760

    Topics: Dihydroxyphenylalanine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Methods; Neurologic Ma

1971

Other Studies

13 other studies available for dihydroxyphenylalanine and Focal Neurologic Deficits

ArticleYear
Predictive test for Huntington's chorea.
    Lancet (London, England), 1970, Dec-05, Volume: 2, Issue:7684

    Topics: Dihydroxyphenylalanine; Humans; Huntington Disease; Movement Disorders; Neurologic Examination; Neur

1970
Chronic manganese intoxication.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adult; Diagnosis, Differential; Dihydroxyphenylalanine; Edetic Acid; Environmental Exposure; Evaluat

1974
[Shy-Drager disease. Hemodynamic and pharmacodynamic studies. Value of cyproheptadine].
    Revue neurologique, 1972, Volume: 126, Issue:6

    Topics: Cyproheptadine; Dihydroxyphenylalanine; Fecal Incontinence; Female; Humans; Hypotension, Orthostatic

1972
[Correction by L-dopa of neurologic manifestations of a chronic portocaval encephalopathy].
    Revue neurologique, 1972, Volume: 127, Issue:5

    Topics: Alcoholism; Ammonia; Brain Diseases; Dihydroxyphenylalanine; Electroencephalography; Humans; Ketoglu

1972
Chronic manganism. Neurologic and laboratory studies during treatment with levodopa.
    JAMA, 1971, Sep-06, Volume: 217, Issue:10

    Topics: Administration, Oral; Adult; Chronic Disease; Dihydroxyphenylalanine; Edetic Acid; Facial Expression

1971
Micrographia in Parkinson's disease.
    Journal of the neurological sciences, 1972, Volume: 15, Issue:2

    Topics: 1-Propanol; Dihydroxyphenylalanine; Female; Handwriting; Humans; Male; Neurologic Manifestations; Pa

1972
Treatment of Parkinson's disease.
    The Journal of the Kentucky Medical Association, 1972, Volume: 70, Issue:4

    Topics: Amantadine; Counseling; Dihydroxyphenylalanine; Humans; Neurologic Manifestations; Parkinson Disease

1972
[Effect of 3,4-dihydroxyphenylalanine (levodopa) in hepatic coma].
    Archivos de investigacion medica, 1972, Volume: 3, Issue:1

    Topics: Administration, Oral; Adult; Aged; Dihydroxyphenylalanine; Electroencephalography; Female; Hepatic E

1972
[L-dopa induced psychosis-dyskinesia complex].
    No to shinkei = Brain and nerve, 1972, Volume: 14, Issue:3

    Topics: Dihydroxyphenylalanine; Female; Humans; Middle Aged; Movement Disorders; Neurologic Manifestations;

1972
Adverse clinical side effects of levodopa therapy.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede

1971
Convulsive seizures and electroencephalogram changes in three patients during levodopa therapy.
    Neurology, 1970, Volume: 20, Issue:12

    Topics: Aged; Brain; Dihydroxyphenylalanine; Electroencephalography; Female; Humans; Male; Middle Aged; Neur

1970
Reversal by levodopa of cholinergic hypersensitivity in Parkinson's disease.
    The New England journal of medicine, 1971, Feb-25, Volume: 284, Issue:8

    Topics: Brain; Dihydroxyphenylalanine; Dopamine; Drug Hypersensitivity; Female; Handwriting; Humans; Injecti

1971
[L-DOPA therapy of parkinsonism].
    Nordisk medicin, 1969, May-01, Volume: 81, Issue:18

    Topics: Animals; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Neurologic Manifestations; Parkinso

1969