dihydroxyphenylalanine has been researched along with Experimental Neoplasms in 85 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The carboxylic ionophore monensin inhibits the activity of tyrosine 3-monooxygenase and decreases the rate of catecholamine synthesis in pheochromocytoma cells incubated in vitro." | 7.66 | Monensin inhibits catecholamine synthesis in pheochromocytoma cells. ( Liang, BT; Perlman, RL; Sheard, BE; Vaccaro, KK, 1982) |
| "This study analyzed the free and protein-bound forms of dopa, 5-S-cysteinyldopa (5-S-CD), and 5-S-glutathionedopa (5-S-GD) in B16 and Harding-Passey (HP) mouse melanomas to investigate the role of these catechols for melanogenesis and melanosome morphogenesis, inasmuch as these tumors produce melanosomes different in color and ultrastructure, i." | 7.66 | Characterization of structural properties for morphologic differentiation of melanosomes. III. free and protein-bound dopa and 5-S-cysteinyldopa in B16 and Harding-Passey melanomas. ( Fujita, K; Homma, K; Ito, S; Jimbow, K; Kiyota, M, 1983) |
| "The activities of NADP-linked dehydrogenases in the cytosol of amelanotic, black melanotic and brown melanotic hamster melanoma are presented." | 7.66 | The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanoma. ( Scisłowski, PW; Słominski, A, 1983) |
| "The effect of dopa, cysteine, and glutathione on 5-S-cysteinyldopa (5-S-CD) genesis in melanoma cells cultured in normal and tyrosine- and cysteine-free media has been studied." | 7.66 | Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro. ( Ichihashi, M; Mishima, Y; Mojamdar, M, 1982) |
| "The effects of theophylline and melanocyte-stimulating hormone on B16 melanoma cells in culture cells were studied by electron microscopy and dopa cytochemistry." | 7.66 | Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture. ( Hu, F; Mah, K; Teramura, DJ, 1982) |
| "The growth inhibitory effect of 6-hydroxydopa, a cytotoxic analog of L-dopa, was studied in melanotic and amelanotic Cloudman melanoma, mouse fibroblast L929 and Chinese hamster ovary cells." | 7.66 | Selective toxicity of 6-hydroxydopa for melanoma cells. ( Byers, L; Ratliff, J; Wick, MM, 1979) |
| "The concentrations of dopa and 5-S-cysteinyldopa were determined in the various cell fractions of Harding-Passey melanomas." | 7.65 | Intracellular distribution of dopa and 5-S-cysteinyldopa in Harding-Passey melanoma. ( Agrup, G; Falck, B; Rorsman, H; Rosengren, AM; Rosengren, E, 1977) |
| "The carboxylic ionophore monensin inhibits the activity of tyrosine 3-monooxygenase and decreases the rate of catecholamine synthesis in pheochromocytoma cells incubated in vitro." | 3.66 | Monensin inhibits catecholamine synthesis in pheochromocytoma cells. ( Liang, BT; Perlman, RL; Sheard, BE; Vaccaro, KK, 1982) |
| "This study analyzed the free and protein-bound forms of dopa, 5-S-cysteinyldopa (5-S-CD), and 5-S-glutathionedopa (5-S-GD) in B16 and Harding-Passey (HP) mouse melanomas to investigate the role of these catechols for melanogenesis and melanosome morphogenesis, inasmuch as these tumors produce melanosomes different in color and ultrastructure, i." | 3.66 | Characterization of structural properties for morphologic differentiation of melanosomes. III. free and protein-bound dopa and 5-S-cysteinyldopa in B16 and Harding-Passey melanomas. ( Fujita, K; Homma, K; Ito, S; Jimbow, K; Kiyota, M, 1983) |
| "The activities of NADP-linked dehydrogenases in the cytosol of amelanotic, black melanotic and brown melanotic hamster melanoma are presented." | 3.66 | The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanoma. ( Scisłowski, PW; Słominski, A, 1983) |
| "The natural catecholic amino acid 5-S-cysteinyl-3,4-dihydroxyphenylalanine (1) was selectively toxic to a variety of human tumor cell lines in culture and exhibited antitumor activity against L1210 leukemia and B-16 melanoma in mice at doses which were not toxic to the host." | 3.66 | Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalanines and related compounds. ( Fujita, K; Inoue, S; Ito, S; Yamamoto, Y, 1981) |
| "The effect of dopa, cysteine, and glutathione on 5-S-cysteinyldopa (5-S-CD) genesis in melanoma cells cultured in normal and tyrosine- and cysteine-free media has been studied." | 3.66 | Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro. ( Ichihashi, M; Mishima, Y; Mojamdar, M, 1982) |
| "The effects of theophylline and melanocyte-stimulating hormone on B16 melanoma cells in culture cells were studied by electron microscopy and dopa cytochemistry." | 3.66 | Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture. ( Hu, F; Mah, K; Teramura, DJ, 1982) |
| "The growth inhibitory effect of 6-hydroxydopa, a cytotoxic analog of L-dopa, was studied in melanotic and amelanotic Cloudman melanoma, mouse fibroblast L929 and Chinese hamster ovary cells." | 3.66 | Selective toxicity of 6-hydroxydopa for melanoma cells. ( Byers, L; Ratliff, J; Wick, MM, 1979) |
| "Cells prepared from a transplantable rat pheochromocytoma synthesize norepinephrine from 14C-tyrosine, at a rate of 9." | 3.65 | Regulation of catecholamine biosynthesis in a transplantable rat pheochromocytoma. ( Chalfie, M; Perlman, RL, 1977) |
| "The concentrations of dopa and 5-S-cysteinyldopa were determined in the various cell fractions of Harding-Passey melanomas." | 3.65 | Intracellular distribution of dopa and 5-S-cysteinyldopa in Harding-Passey melanoma. ( Agrup, G; Falck, B; Rorsman, H; Rosengren, AM; Rosengren, E, 1977) |
| "Phenylalanine hydroxylase in Reuber H4 hepatoma cell cultures can be rapidly inactivated by the addition of epinephrine, norepinephrine, dopamine, or 3,4-dihydroxyphenylalanine, in order of decreasing effectiveness, to the culture medium." | 1.26 | Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells. ( Miller, MR; Shiman, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (98.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (1.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martiniova, L | 1 |
| Cleary, S | 1 |
| Lai, EW | 1 |
| Kiesewetter, DO | 1 |
| Seidel, J | 1 |
| Dawson, LF | 1 |
| Phillips, JK | 1 |
| Thomasson, D | 1 |
| Chen, X | 1 |
| Eisenhofer, G | 1 |
| Powers, JF | 1 |
| Kvetnansky, R | 1 |
| Pacak, K | 1 |
| HEMPEL, K | 4 |
| ERB, W | 1 |
| DAY, M | 1 |
| GREEN, JP | 1 |
| DOMENJOZ, R | 1 |
| SCHELLENBERG, H | 1 |
| SEIJI, M | 6 |
| IWASHITA, S | 1 |
| DEIMEL, M | 1 |
| BLOIS, MS | 1 |
| KALLMAN, RF | 1 |
| HIRSCH, HM | 2 |
| ZELICKSON, AS | 2 |
| HARTMANN, JF | 1 |
| Dernalowicz, E | 1 |
| Trojanowski, J | 1 |
| Bomirski, A | 3 |
| Dominiczak, T | 1 |
| Vaccaro, KK | 1 |
| Liang, BT | 1 |
| Sheard, BE | 2 |
| Perlman, RL | 3 |
| Bräutigam, M | 1 |
| Dreesen, R | 1 |
| Flosbach, CW | 1 |
| Herken, H | 1 |
| Tischler, AS | 1 |
| Morse, GM | 1 |
| Ito, S | 5 |
| Homma, K | 1 |
| Kiyota, M | 1 |
| Fujita, K | 4 |
| Jimbow, K | 2 |
| Miranda, M | 1 |
| Botti, D | 1 |
| Scisłowski, PW | 1 |
| Słominski, A | 1 |
| Inoue, S | 2 |
| Mishima, Y | 4 |
| Imokawa, G | 1 |
| White, R | 1 |
| Hu, F | 3 |
| Roman, NA | 1 |
| Miura, S | 1 |
| Ito, Y | 1 |
| Kasuga, T | 1 |
| Gavrilenko, IS | 3 |
| Rumjancev, PP | 1 |
| Bulycev, AG | 1 |
| Zarembskij, RA | 1 |
| Ivanov, II | 4 |
| Teradaira, R | 1 |
| Yamamoto, Y | 1 |
| Mojamdar, M | 1 |
| Ichihashi, M | 1 |
| Mah, K | 1 |
| Teramura, DJ | 1 |
| Körner, A | 1 |
| Pawelek, J | 1 |
| Chalfie, M | 1 |
| Agrup, G | 1 |
| Falck, B | 1 |
| Rorsman, H | 1 |
| Rosengren, AM | 2 |
| Rosengren, E | 1 |
| Fraeyman, NH | 1 |
| De Potter, WP | 1 |
| De Schaepdryver, AF | 1 |
| Pawelek, JM | 1 |
| Miller, MR | 1 |
| Shiman, R | 1 |
| Zarembskiĭ, RA | 1 |
| Bobrova, VN | 3 |
| Rumiantseva, LN | 3 |
| Wick, MM | 1 |
| Byers, L | 1 |
| Ratliff, J | 1 |
| Berkelhammer, J | 1 |
| Caines, SM | 1 |
| Dexter, DL | 1 |
| Adelstein, EH | 1 |
| Oxenhandler, RW | 1 |
| Hook, RR | 1 |
| Hearing, VJ | 1 |
| Ekel, TM | 1 |
| Wrzolkowa, T | 1 |
| Oikawa, A | 1 |
| Hutton, IM | 2 |
| Tebbutt, S | 1 |
| Castro, JE | 1 |
| Stringer, MJ | 2 |
| Stock, JA | 2 |
| Cobb, LM | 2 |
| Pentland, M | 1 |
| Chou, SC | 1 |
| Yang, CF | 1 |
| Kimler, VA | 1 |
| Taylor, JD | 1 |
| Tchen, TT | 1 |
| Elford, HL | 1 |
| van't Riet, B | 1 |
| Haberman, HF | 2 |
| Menon, IA | 2 |
| Pretlow, TG | 1 |
| Boone, CW | 1 |
| Zawrocka-Wrzolkowa, T | 1 |
| Pautsch, F | 1 |
| Patel, RP | 2 |
| Okun, MR | 3 |
| Yee, WA | 1 |
| Wilgram, GF | 1 |
| Edelstein, LM | 2 |
| Fukuzawa, H | 2 |
| Miyazaki, N | 1 |
| Akiba, H | 1 |
| Kato, T | 1 |
| Shimao, K | 1 |
| Duke, PS | 1 |
| Hourani, BT | 1 |
| Demopoulos, HB | 1 |
| Stellar, S | 1 |
| Cooper, IS | 1 |
| Axelsson, S | 1 |
| Cegrell, L | 1 |
| Donnellan, B | 2 |
| Pearson, SH | 1 |
| Edelstein, LE | 1 |
| Gan, EV | 1 |
| Malarkey, WB | 1 |
| Daughaday, WH | 1 |
| Hamada, T | 1 |
| Nagatsu, T | 1 |
| Sudo, I | 1 |
| Okada, T | 1 |
| Umezawa, H | 1 |
| Takeuchi, T | 1 |
| Vdovenko, VM | 2 |
| Pomerantz, SH | 3 |
| Warner, MC | 2 |
| Morgan, LR | 1 |
| Singh, R | 1 |
| Sylvest, V | 1 |
| Weimorts, D | 1 |
| Prabhakaran, K | 1 |
| Yoshida, T | 1 |
| Itakura, H | 1 |
| Irimajiri, T | 1 |
| Adams, JF | 1 |
| Aubert, C | 1 |
| Bohuon, C | 1 |
| Comoy, E | 1 |
| Stanka, P | 1 |
| Kinzel, V | 1 |
| Mohr, U | 1 |
| Saunders, RN | 1 |
| Miya, TS | 1 |
| Bousquet, WF | 1 |
| Van Woert, MH | 1 |
| Miyazaki, K | 2 |
| Cobb, JP | 1 |
| McGrath, A | 1 |
| Otaki, N | 1 |
| Fischer, R | 1 |
| Schachtschabel, D | 1 |
| Zilliken, F | 1 |
| Davidson, R | 1 |
| Epstein, WL | 1 |
| Fukuyama, K | 1 |
| Volina, VV | 1 |
| Grässmann, A | 1 |
| Grässmann, M | 1 |
| Voorhess, ML | 1 |
| Håkanson, R | 1 |
| Möller, H | 1 |
| Stormby, NG | 1 |
| Takahashi, H | 1 |
| Fitzpatrick, TB | 1 |
| Männl, HF | 1 |
3 reviews available for dihydroxyphenylalanine and Experimental Neoplasms
| Article | Year |
|---|---|
Factors regulating growth and pigmentation of melanoma cells.
Topics: Animals; Bone Neoplasms; Bromodeoxyuridine; Catechol Oxidase; Cell Division; Cell Line; Cell Transfo | 1976 |
[Melanocyte and melanin (author's transl)].
Topics: Animals; Carotenoids; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Decapodiformes; Di | 1976 |
Inhibition of nucleoside diphosphate reductase by hydroxybenzohydroxamic acid derivatives.
Topics: Animals; Antineoplastic Agents; Basidiomycota; Deoxyribonucleotides; Dihydroxyphenylalanine; Drug Sy | 1985 |
82 other studies available for dihydroxyphenylalanine and Experimental Neoplasms
| Article | Year |
|---|---|
Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Animals; Contrast Media; Dihydroxyphenylalanine; Dopamine; Female; Liver Ne | 2012 |
[Autoradiographic studies on protein and melanin metabolism in different cell types in melanoma in mice (Harding-Passey type)].
Topics: Animals; Autoradiography; Dihydroxyphenylalanine; Melanins; Melanoma; Mice; Neoplasms; Neoplasms, Ex | 1962 |
The uptake of amino acids and the synthesis of amines by neoplastic mast cells in culture.
Topics: Amines; Amino Acids; Dihydroxyphenylalanine; Histamine; Histidine; Mast Cells; Neoplasms; Neoplasms, | 1962 |
[Pharmacological studies on 5-hydroxytryptamine metabolism in mastocytoma].
Topics: Chlorpromazine; Dihydroxyphenylalanine; Imipramine; Iproniazid; Isocarboxazid; Mastocytoma; Mastocyt | 1962 |
ON THE SITE OF MELANIN FORMATION IN MELANOCYTES.
Topics: Animals; Carbon Isotopes; Cell Biology; Chromatophores; Dihydroxyphenylalanine; Liver; Melanins; Mel | 1963 |
[EFFECT OF THE DOPA-DECARBOXYLASE INHIBITOR ALPHA-METHYLDOPA ON THE INCORPORATION OF DOPA INTO MELANIN AND PYROCATECHOLAMINE. IN VIVO STUDIES ON MELANOMA MICE WITH TRITIATED DOPA].
Topics: Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Dihydroxyphenylalanine; Dopa Deca | 1963 |
THE INCORPORATION OF C14 FROM 3,4-DIHYDROXYPHENYLALANINE-2'-C14 INTO THE MELANIN OF MOUSE MELANOMAS.
Topics: Animals; Carbon Isotopes; Dihydroxyphenylalanine; Melanins; Melanoma; Metabolism; Mice; Neoplasms; N | 1964 |
AN ENZYMATIC AND ELECTRON MICROSCOPIC CHARACTERIZATION OF A VARIANT OF THE CLOUDMAN S-91 MELANOMA.
Topics: Animals; Dihydroxyphenylalanine; Electrons; Enzyme Inhibitors; Histocytochemistry; Melanins; Melanom | 1964 |
MELANOGENESIS: AN AUTORADIOGRAPHIC STUDY AT THE ULTRASTRUCTURAL LEVEL.
Topics: Animals; Autoradiography; Dihydroxyphenylalanine; Electrons; Histocytochemistry; Melanins; Melanoma; | 1964 |
Tyrosinase activity in the amelanotic melanoma in golden hamsters.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Hydroxylamines; Kidney; Liver; Manometry; Melanoma; Neo | 1967 |
Monensin inhibits catecholamine synthesis in pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Catecholamines; Cells, Cultured; Chromaffin Granules; Dihydroxyphe | 1982 |
Mouse neuroblastoma clone N1E-115: a suitable model for studying the action of dopamine agonists of tyrosine hydroxylase activity.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Catecholamines; Cells, Cultured; Clone Cells; Dihydro | 1982 |
Glucocorticoids increase catecholamine synthesis and storage in PC12 pheochromocytoma cell cultures.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Cholera Toxin; Corticosterone; Dexamethasone; Dihydroxy | 1983 |
Characterization of structural properties for morphologic differentiation of melanosomes. III. free and protein-bound dopa and 5-S-cysteinyldopa in B16 and Harding-Passey melanomas.
Topics: Animals; Cysteinyldopa; Dihydroxyphenylalanine; Hair; Melanocytes; Melanoma; Mice; Neoplasms, Experi | 1983 |
Harding-passey mouse-melanoma tyrosinase inactivation by reaction products and activation by L-epinephrine.
Topics: Animals; Catechol Oxidase; Dihydroxyphenylalanine; Enzyme Activation; Epinephrine; Melanins; Melanom | 1983 |
The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanoma.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Electrophoresis, Polyacrylamide Gel; Hydroxylation; Mel | 1983 |
The mechanism of toxicity of 5-S-cysteinyldopa to tumour cells. Hydrogen peroxide as a mediator of cytotoxicity.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cysteinyldopa; Dihydroxyphenylalanine; Dop | 1983 |
Selective aberration and pigment loss in melanosomes of malignant melanoma cells in vitro by glycosylation inhibitors: premelanosomes as glycoprotein.
Topics: Animals; Dihydroxyphenylalanine; Glucosamine; Melanins; Melanocytes; Melanoma; Mice; Microscopy, Ele | 1983 |
False dopa reaction in studies of mammalian tyrosinase: some characteristics and precautions.
Topics: Animals; Catechol Oxidase; Cells, Cultured; Dihydroxyphenylalanine; False Positive Reactions; Fibrob | 1983 |
[Utilization of melanin precursors for experimental chemotherapy of malignant melanoma].
Topics: Animals; Catecholamines; Cysteamine; Cysteine; Dihydroxyphenylalanine; Melanins; Melanocytes; Melano | 1984 |
[Tritiated DOPA: distribution in the subcellular melanoma fractions and perspective of its radiotherapeutical use (author's transl)].
Topics: Animals; Dihydroxyphenylalanine; Melanoma; Mice; Microscopy, Electron; Neoplasms, Experimental; Radi | 1980 |
Distribution and metabolism of tritiumlabelled 5-S-cysteinyldopa in mice.
Topics: Animals; Cysteinyldopa; Dihydroxyphenylalanine; Levodopa; Male; Melanoma; Mice; Mice, Inbred Strains | 1980 |
Synthesis and antitumor activity of cysteinyl-3,4-dihydroxyphenylalanines and related compounds.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cricetinae; Cysteinyldopa; Dihydroxyphenyl | 1981 |
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro.
Topics: Animals; Cells, Cultured; Cricetinae; Culture Media; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine | 1982 |
Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture.
Topics: Animals; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; Melanocyte-Stimulating Hormones; Melano | 1982 |
Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin.
Topics: Catechol Oxidase; Cells, Cultured; Dihydroxyphenylalanine; Indoles; Kinetics; Melanins; Melanoma; Mo | 1982 |
Regulation of catecholamine biosynthesis in a transplantable rat pheochromocytoma.
Topics: Animals; Brocresine; Calcium; Cells, Cultured; Chromaffin System; Cycloheximide; Dihydroxyphenylalan | 1977 |
Intracellular distribution of dopa and 5-S-cysteinyldopa in Harding-Passey melanoma.
Topics: Animals; Cysteinyldopa; Dihydroxyphenylalanine; Melanoma; Mice; Mice, Inbred DBA; Neoplasms, Experim | 1977 |
Biosynthesis of noradrenaline in C1300 mouse neuroblastoma [proceedings].
Topics: Animals; Dihydroxyphenylalanine; Mice; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Pheny | 1978 |
Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Catecholamines; Cell Line; Dihydroxyphenylalanine; Dopamine; Epinephrine; | 1976 |
[Regulatory role of DOPA and components of the cyclic adenosine-3',5'-monophosphate system].
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dihydroxyphenylalanine; Melanoma; Mice; Neoplasms, Experimen | 1978 |
Selective toxicity of 6-hydroxydopa for melanoma cells.
Topics: Animals; Cells, Cultured; Cricetinae; Dihydroxyphenylalanine; Growth Inhibitors; Melanoma; Mice; Neo | 1979 |
Adaptation of Sinclair swine melanoma cells to long-term growth in vitro.
Topics: Animals; Cell Division; Cell Line; Dihydroxyphenylalanine; Female; Male; Melanoma; Neoplasm Regressi | 1979 |
Involvement of tyrosinase in melanin formation in murine melanoma.
Topics: Animals; Catechol Oxidase; Cell Line; Chelating Agents; Chromatography, DEAE-Cellulose; Dihydroxyphe | 1975 |
Ultrastructural tyrosine reaction in hamster melanoma.
Topics: Animals; Catechol Oxidase; Cricetinae; Dihydroxyphenylalanine; Endoplasmic Reticulum; Hydroxylation; | 1975 |
Dopa uptake by human melanomas maintained in immunosuppressed mice.
Topics: Animals; Colonic Neoplasms; Dihydroxyphenylalanine; Female; Humans; Immunosuppression Therapy; Melan | 1977 |
Proceedings: Distribution studies with an aminophosphonic and analogue of DOPA in mice bearing the Harding-Passey melanoma.
Topics: Animals; Dihydroxyphenylalanine; Melanoma; Mice; Neoplasms, Experimental | 1975 |
Uptake of melanin precursors in mouse melanoma.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Female; Melanins; Melanoma; Mice; Mice, Inbred CBA; Neopl | 1976 |
Reversible dedifferentiation and redifferentiation of a melanized cell line from a goldfish tumor.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Culture Media; Dihydroxyphenylalanine; Electrop | 1989 |
Presence and properties of tyrosinase in sera of melanoma-bearing animals.
Topics: Animals; Blood; Catechol Oxidase; Centrifugation, Density Gradient; Chromatography; Cricetinae; Dihy | 1971 |
Separation of malignant cells from transplantable rodent tumors.
Topics: Animals; Cell Count; Centrifugation, Density Gradient; Centrifugation, Zonal; Clone Cells; Culture T | 1970 |
Electron microscopic studies on transplantable melanotic and amelanotic melanomas in hamsters.
Topics: Animals; Catechol Oxidase; Chromatophores; Cricetinae; Cytoplasm; Cytoplasmic Granules; Dihydroxyphe | 1973 |
Inability of murine melanoma "tyrosinase" (dopa ozidase) to oxidize tyrosine in the presence or absence of dopa or dihydroxyfumarate cofactor.
Topics: Animals; Catechol Oxidase; Chromatography; Dihydroxyphenylalanine; Fumarates; Hydrogen-Ion Concentra | 1973 |
Regulatory mechanisms of tyrosinase activity in melanocyte. I.
Topics: Allosteric Regulation; Animals; Carbon Radioisotopes; Catechol Oxidase; Cell Fractionation; Cell Lin | 1973 |
The synthesis of a DOPA analogue, 1-amino-2-(3, 4-dihydroxyphenyl)-ethylphosphonic acid and distribution studies in mice bearing the Harding-Passey melanoma.
Topics: Adrenal Glands; Animals; Basidiomycota; Catechol Oxidase; Chromatography, Thin Layer; Dihydroxypheny | 1974 |
Inactivation mechanism of tyrosinase.
Topics: Animals; Catechol Oxidase; Dihydroxyphenylalanine; Kinetics; Mathematics; Melanins; Melanoma; Mice; | 1974 |
Study of S91 mouse melanomas by electron paramagnetic resonance (EPR) spectroscopy and tissue culture. II. Effects of penicillamine on EPR signals and on growth in vitro.
Topics: Animals; Chromatography, Paper; Copper; Culture Techniques; Dihydroxyphenylalanine; Electron Spin Re | 1967 |
Recent advances in neurosurgical treatment for the elderly.
Topics: Aged; Animals; Brain Neoplasms; Cats; Central Nervous System Diseases; Cerebral Angiography; Cryosur | 1970 |
Tyrosine hydroxylase activity in a transplantable islet cell tumour of golden hamster.
Topics: Adenoma, Islet Cell; Amides; Animals; Cricetinae; Dihydroxyphenylalanine; Female; Folic Acid; Hydraz | 1970 |
Melanin: a normal component of human eosinophils.
Topics: Adolescent; Adult; Aged; Animals; Basophils; Catecholamines; Child; Child, Preschool; Color; Dihydro | 1974 |
Oxidation of NADH by melanin and melanoproteins.
Topics: Amino Acids; Animals; Catechol Oxidase; Cattle; Chymotrypsin; Dihydroxyphenylalanine; Kinetics; Mela | 1974 |
[On the biosynthesis and structure of animal melanin. In vivo studies with tritium and 14C-labelled dopa on the mouse Harding-Passey melanoma].
Topics: Animals; Autoradiography; Carbon Isotopes; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Me | 1967 |
The influence of levodopa and adrenergic blockade on growth hormone and prolactin secretion in the MStTW15 tumor bearing rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Depression, Chemical; Dihydroxyp | 1972 |
Intracellular localization of tyrosinase inhibitor in amelanotic and melanotic malignant melanoma.
Topics: Animals; Catechol Oxidase; Cricetinae; Cytoplasm; Dihydroxyphenylalanine; Golgi Apparatus; Melanins; | 1972 |
Inhibition of melanoma tyrosinase by fusaric acid.
Topics: Animals; Catechol Oxidase; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; In Vitro Techniques; M | 1972 |
[The combined action of 2,5,6-H3-DOPA and alkylating agents on Harding-Passy melanoma].
Topics: Animals; Cyclophosphamide; Dihydroxyphenylalanine; Melanoma; Melphalan; Mice; Mice, Inbred BALB C; N | 1972 |
Subcellular demonstration of peroxidatic oxidation of tyrosine to melanin using dihydroxyfumarate as cofactor in mouse melanoma cells.
Topics: Amines; Animals; Biphenyl Compounds; Carbamates; Dihydroxyphenylalanine; Endoplasmic Reticulum; Fuma | 1973 |
Identification of 3,4-dihydroxyphenylalanine as tyrosinase cofactor in melanoma.
Topics: Animals; Coenzymes; Cricetinae; Dihydroxyphenylalanine; Electrophoresis; Enterococcus faecalis; In V | 1966 |
3,4-dihydroxy-L-phenylalanine as the tyrosinase cofactor. Occurrence in melanoma and binding constant.
Topics: Animals; Binding Sites; Carbon Isotopes; Catechol Oxidase; Chromatography, Paper; Cricetinae; Dihydr | 1967 |
Oxidation of o-aminophenols by mouse and human melanoma dihydroxyphenylalanine oxidase and dihydroxyphenylalanine.
Topics: Animals; Antibiotics, Antineoplastic; Catechol Oxidase; Culture Techniques; Dihydroxyphenylalanine; | 1967 |
Properties of phenoloxidase in Mycobacterium leprae.
Topics: Animals; Basidiomycota; Benzoates; Catechol Oxidase; Cinnamates; Dihydroxyphenylalanine; Melanoma; M | 1968 |
Inhibition of melanin formation by sulfhydryl compounds.
Topics: Animals; Carbon Isotopes; Catechol Oxidase; Chromatophores; Culture Techniques; Cysteine; Dihydroxyp | 1969 |
Non-premelanosomal and premelanosomal tyrosinase activity in Greene's amelanotic and melanotic malignant melanoma.
Topics: Animals; Catechol Oxidase; Dihydroxyphenylalanine; Fluorescence; Histocytochemistry; In Vitro Techni | 1969 |
[Urinary excretion of 3,4-dihydroxyphenylalanine (DOPA) and dopamine in hamsters with induced or transplanted melanomas].
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Dopamine; Melanoma; Neoplasm Transplantation; Neoplasms | 1969 |
[Electron microscope study of the origin of premelanosomes in melanoma cells in vitro].
Topics: Animals; Catechol Oxidase; Cricetinae; Culture Techniques; Dihydroxyphenylalanine; Endoplasmic Retic | 1969 |
Stimulation of DOPA14C incorporation into melanoma tissue by chlorpromazine and reserpine.
Topics: Animals; Carbon Isotopes; Catechol Oxidase; Chlorpromazine; Dihydroxyphenylalanine; In Vitro Techniq | 1970 |
Effect of phenothiazines on melanoma tyrosinase activity.
Topics: Adrenal Glands; Animals; Basidiomycota; Carbon Isotopes; Catechol Oxidase; Cell Membrane Permeabilit | 1970 |
Tyrosinase isolated from mouse melanoma melanosome.
Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatogr | 1971 |
Melanization and tyrosinase activity.
Topics: Animals; Binding Sites; Catechol Oxidase; Copper; Dihydroxyphenylalanine; Melanins; Melanocytes; Mel | 1971 |
S91 mouse melanoma sublines following total in vitro versus alternate in vivo passages.
Topics: Animals; Autoradiography; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; DNA, Neoplasm; Histocy | 1972 |
Melanosome and lysosome. II. Digestion of melanosome with mouse liver lysosome.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatophores; Cytoplasmic Granules; Dihydroxyphenylalanine; | 1970 |
[Biochemical studies on the influencing of melanin formation in cell cultures of the Harding-Passey melanoma].
Topics: Animals; Culture Techniques; Depression, Chemical; Dihydroxyphenylalanine; Melanins; Melanoma; Mice; | 1969 |
Interactions between genomes in somatic cell hybrids: studies on the regulation of differentiation.
Topics: Animals; Catechol Oxidase; Cell Differentiation; Cell Fractionation; Cell Line; Chromosomes; Clone C | 1969 |
Light and electron microscopic studies of a transplantable melanoma associated with virus-like particles.
Topics: Acid Phosphatase; Animals; Cricetinae; Cytoplasmic Granules; Dihydroxyphenylalanine; Endoplasmic Ret | 1970 |
[Distribution of pyrocatechol-3,4,5,6-3H4 and 3-(3,4-dihydroxyphenyl)-alanine-2,5,6-3H3 in tissues of mice with Garding-Passy melanoma after single and fractional injections].
Topics: Animals; Catechols; Dihydroxyphenylalanine; Melanoma; Methods; Mice; Neoplasms, Experimental; Tritiu | 1970 |
[The formation of melanin in muscle cells after the direct transfer of RNA from Harding-Passey melanoma cells].
Topics: Animals; Autoradiography; Cell Transformation, Neoplastic; Culture Techniques; Cycloheximide; Deoxyr | 1971 |
Effect of alpha-methyl-p-tyrosine on 3,4-dihydroxyphenylalanine (DOPA) excretion of hamsters with melanotic melanoma.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Female; Injections, Intraperitoneal; Melanoma; Methylty | 1968 |
The developmental cycle of B16 melanoma cell in culture.
Topics: Animals; Chromatophores; Culture Techniques; Dihydroxyphenylalanine; Melanoma; Mice; Neoplasm Transp | 1965 |
DOPA decarboxylase activity in a transplantable hamster melanoma.
Topics: Animals; Carbon Isotopes; Cricetinae; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; In Vitro | 1965 |
Tyrosine hydroxylation catalyzed by mammalian tyrosinase: an improved method of assay.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; In Vitro Techniques; Kinetics; Melanoma; Neoplasms, Exp | 1964 |
Large amounts of deoxyphenylalanine in the hydrolysate of melanosomes from Harding-Passey mouse melanoma.
Topics: Animals; Chromatography, Paper; Dihydroxyphenylalanine; Fluorometry; Melanoma; Mice; Neoplasm Protei | 1966 |
The conversion of [3H]tyrosine to [3H]DOPA in mouse melanoma in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Chromatography, Paper; Dihydroxyphenylalanine; Electrophoresis; | 1966 |