dihydroxyphenylalanine has been researched along with Epilepsy, Tonic-Clonic in 1 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biraben, A | 1 |
| Semah, F | 1 |
| Ribeiro, MJ | 1 |
| Douaud, G | 1 |
| Remy, P | 1 |
| Depaulis, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Dopaminergic Reactivity In Idiopathic Generalized Epilepsy: A Proof Of Concept Clinical, Pharmacological And Neurophysiological Study"[NCT01432821] | 31 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for dihydroxyphenylalanine and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Caudate Nucleus; Chromosome Disorders; Chromosomes, Human, Pair | 2004 |