dihydroxyphenylalanine has been researched along with Epilepsies, Partial in 3 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biraben, A | 1 |
| Semah, F | 1 |
| Ribeiro, MJ | 1 |
| Douaud, G | 1 |
| Remy, P | 1 |
| Depaulis, A | 1 |
| Karlov, VA | 1 |
| Gleĭzer, MA | 1 |
| Goldstein, DS | 1 |
| Nadi, NS | 1 |
| Stull, R | 1 |
| Wyler, AR | 1 |
| Porter, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Dopaminergic Reactivity In Idiopathic Generalized Epilepsy: A Proof Of Concept Clinical, Pharmacological And Neurophysiological Study"[NCT01432821] | 31 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for dihydroxyphenylalanine and Epilepsies, Partial
| Article | Year |
|---|---|
PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Caudate Nucleus; Chromosome Disorders; Chromosomes, Human, Pair | 2004 |
[Reactivity of the DOPA--dopamine--noradrenaline--adrenaline system in epileptics].
Topics: Adolescent; Adult; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epilepsies, Partial; Epilepsy; | 1983 |
Levels of catechols in epileptogenic and nonepileptogenic regions of the human brain.
Topics: Adult; Brain; Dihydroxyphenylalanine; Dopamine; Epilepsies, Partial; Epinephrine; Humans; Methoxyhyd | 1988 |