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dihydroxyphenylalanine and Endocrine Gland Neoplasms

dihydroxyphenylalanine has been researched along with Endocrine Gland Neoplasms in 5 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Endocrine Gland Neoplasms: Tumors or cancer of the ENDOCRINE GLANDS.

Research Excerpts

ExcerptRelevanceReference
"In detecting pheochromocytoma (PHEO), positron emission tomography (PET) with the radiolabelled amine precursor (18)F-fluorodihydroxyphenylalanine ((18)F-DOPA) offers excellent specificity, while computed tomography (CT) provides high sensitivity and ability to localize lesions; therefore, the combination of these modalities could be advantageous in this setting."7.76Clinical value of 18F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET/CT) for detecting pheochromocytoma. ( Buck, AK; Dralle, H; Glatting, G; Karges, W; Luster, M; Mottaghy, FM; Neumaier, B; Pauls, S; Reske, SN; Solbach, C; Verburg, FA; Zeich, K, 2010)
"In detecting pheochromocytoma (PHEO), positron emission tomography (PET) with the radiolabelled amine precursor (18)F-fluorodihydroxyphenylalanine ((18)F-DOPA) offers excellent specificity, while computed tomography (CT) provides high sensitivity and ability to localize lesions; therefore, the combination of these modalities could be advantageous in this setting."3.76Clinical value of 18F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET/CT) for detecting pheochromocytoma. ( Buck, AK; Dralle, H; Glatting, G; Karges, W; Luster, M; Mottaghy, FM; Neumaier, B; Pauls, S; Reske, SN; Solbach, C; Verburg, FA; Zeich, K, 2010)
"Seventy-seven consecutive carcinoid patients who underwent an 18F-dopa PET scan in two previously published studies were analysed."1.37Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour. ( Brouwers, AH; de Jong, JR; de Vries, EG; Dierckx, RA; Fiebrich, HB; Kema, IP; Koopmans, KP; Links, TP; Sluiter, W; Walenkamp, AM, 2011)
"The greatest impact was observed for carcinoid tumors (50%: 11 of 22) and was clinically relevant in every case, followed by occult endocrine tumors (16%: four of 25), and was clinically relevant in three of the four cases, and noncarcinoid tumors (13%: 3 of 22), clinically relevant in only one case."1.35Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors. ( Bouchard, P; Duron, F; Grangé, JD; Houry, S; Huchet, V; Kerrou, K; Lotz, JP; Montravers, F; Nataf, V; Rougier, P; Ruszniewski, P; Talbot, JN, 2009)
"Conversely, in noncarcinoid tumors, the extent of the disease was more accurately evaluated in all cases by (111)In-pentetreotide SRS than by (18)F-FDOPA PET."1.33Can fluorodihydroxyphenylalanine PET replace somatostatin receptor scintigraphy in patients with digestive endocrine tumors? ( Aide, N; de Beco, V; Grahek, D; Grangé, JD; Gutman, F; Kerrou, K; Lotz, JP; Montravers, F; Ruszniewski, P; Talbot, JN, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montravers, F2
Kerrou, K2
Nataf, V1
Huchet, V1
Lotz, JP2
Ruszniewski, P2
Rougier, P1
Duron, F1
Bouchard, P1
Grangé, JD2
Houry, S1
Talbot, JN2
Luster, M1
Karges, W1
Zeich, K1
Pauls, S1
Verburg, FA1
Dralle, H1
Glatting, G1
Buck, AK1
Solbach, C1
Neumaier, B1
Reske, SN1
Mottaghy, FM1
Dudczak, R1
Traub-Weidinger, T1
Fiebrich, HB1
de Jong, JR1
Kema, IP1
Koopmans, KP1
Sluiter, W1
Dierckx, RA1
Walenkamp, AM1
Links, TP1
Brouwers, AH1
de Vries, EG1
Grahek, D1
de Beco, V1
Aide, N1
Gutman, F1

Reviews

1 review available for dihydroxyphenylalanine and Endocrine Gland Neoplasms

ArticleYear
PET and PET/CT in endocrine tumours.
    European journal of radiology, 2010, Volume: 73, Issue:3

    Topics: Carbon Radioisotopes; Dihydroxyphenylalanine; Endocrine Gland Neoplasms; Fluorodeoxyglucose F18; Gal

2010

Other Studies

4 other studies available for dihydroxyphenylalanine and Endocrine Gland Neoplasms

ArticleYear
Impact of fluorodihydroxyphenylalanine-18F positron emission tomography on management of adult patients with documented or occult digestive endocrine tumors.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Adult; Biopsy; Carcinoid Tumor; Dihydroxyphenylalanine; Endocrine Gland Neoplasms; Fluorodeoxyglucos

2009
Clinical value of 18F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET/CT) for detecting pheochromocytoma.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Biological Transport; Child; Dihydroxyphenylalanine; Endocrine Gland Neopla

2010
Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour.
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Biological Transport; Carcinoid Tumor; Dihydroxyphenylalanine; Endocrine Gl

2011
Can fluorodihydroxyphenylalanine PET replace somatostatin receptor scintigraphy in patients with digestive endocrine tumors?
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:9

    Topics: Adult; Aged; Carcinoid Tumor; Digestive System Neoplasms; Dihydroxyphenylalanine; Endocrine Gland Ne

2006