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dihydroxyphenylalanine and Encephalitis Lethargica Type Parkinsonism

dihydroxyphenylalanine has been researched along with Encephalitis Lethargica Type Parkinsonism in 52 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Research Excerpts

ExcerptRelevanceReference
"Many of the clinical features of this postencephalitic parkinsonism (PEP) suggested the diagnosis of sporadic encephalitis lethargica, first described by von Economo 1917."1.31FDG- and Dopa-PET in postencephalitic parkinsonism. ( Bamborschke, S; Ghaemi, M; Heiss, WD; Rudolf, J; Schmülling, S, 2000)
"Treatment with tetrabenazine did not significantly alter the metabolite levels in patients in whom it produced either improvement, or side effects."1.26CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders. ( Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM, 1977)
" Patients with postencephalitic Parkinsonism may respond as well as patients with Parkinson's disease to levodopa but they develop both favourable responses and side-effects at a lower dosage and require careful dosage adjustments and close surveillance."1.25Response of patients with postencephalitic Parkinsonism to levodopa. ( Duvoisin, RC; Lobo-Antunes, J; Yahr, MD, 1972)
" Some of the common side effects of l-dopa administration can be averted or controlled by a cautious and slow build-up to the optimal dosage level."1.25Treatment of Parkinson's disease with L-dopa: a current appraisal. ( Kofman, O, 1971)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199051 (98.08)18.7374
1990's0 (0.00)18.2507
2000's1 (1.92)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghaemi, M1
Rudolf, J1
Schmülling, S1
Bamborschke, S1
Heiss, WD1
Davidson, DL1
Yates, CM1
Mawdsley, C2
Pullar, IA1
Wilson, H1
Kandel', EI1
Iadgarov, IS1
Hunter, KR1
Stern, GM3
Sharkey, J2
Yahr, MD3
Antonini, F1
Baroni, A1
Bucalossi, A1
Roveyaz, L1
Calne, DB2
Laurence, DR2
Armitage, P1
Spiers, AS1
Sacks, OW3
Kohl, M1
Godwin-Austen, RB1
Frears, CC1
Bergmann, S1
Parkes, JD2
Knill-Jones, RP1
Crawford, JP1
Bernheimer, H1
Birkmayer, W1
Hornykiewicz, O1
Hartmann-von Monakow, K2
Julsrud, OJ1
Presthus, J1
Holmsen, R1
Laitinen, L1
Rosati, G1
Agnetti, V1
Mura, F1
Granieri, E1
Haleem, MA1
Shapiro, SK1
Lipman, IJ1
Papadopoulos, NM1
Rinne, UK3
Riekkinen, P1
Sonninen, V3
Laaksonen, H1
Gerstenbrand, F1
Grünberger, J1
Schubert, H1
Strelkova, NI1
Zeĭnalov, RK1
Sevilla, M1
Vernet, JP1
Becle, J1
Darcourt, G1
Siirtola, T1
Stoliarova, LG1
Kistenev, BA1
Powell, HC1
London, GW1
Lampert, PW1
Lieberman, AN1
Baxter, RC1
Marsden, CD1
Rees, JE1
Gamsu, CV1
Sigwald, J2
Raymondeaud, C1
Piot, C1
Albert, E1
Worm-Petersen, J1
Dupont, E1
Mikkelsen, B1
McDowell, FH1
Markham, CH1
Lee, JE1
Treciokas, LJ1
Ansel, RD1
Duvoisin, RC2
Lobo-Antunes, J1
Guidetti, B1
Giuffrè, R1
Ross, SJ1
DePaola, DP1
Kohl, MS1
Stern, G1
Klawans, HL1
Goodwin, JA1
Bergamini, L1
Bonzanino, O1
Brignolio, F1
Fabiani, A1
Fariello, R1
Mombelli, AM1
Mutani, R1
Pisani, W1
Postir, A1
Riccio, A1
Sabbatini, F1
Sandigliano, G1
Schiffer, D1
Völler, GW1
Kerstan, J1
Celesia, GG1
Barr, AN1
Messeloff, CR1
Schwartz, WF1
Krasner, N1
Cornelius, JM1
Bonduelle, M1
Kofman, O1
Schear, MJ1
Barrett, RE1
Hoehn, MM1

Reviews

2 reviews available for dihydroxyphenylalanine and Encephalitis Lethargica Type Parkinsonism

ArticleYear
The treatment of parkinsonism. Current concepts.
    The Medical clinics of North America, 1972, Volume: 56, Issue:6

    Topics: Acetylcholine; Antiparkinson Agents; Blood-Brain Barrier; Dihydroxyphenylalanine; Dopamine; Drug Syn

1972
[Therapy and problems of parkinsonism].
    Der Nervenarzt, 1971, Volume: 42, Issue:5

    Topics: Adult; Aged; Amantadine; Animals; Antidepressive Agents; Apomorphine; Brain Chemistry; Brain Stem; D

1971

Trials

8 trials available for dihydroxyphenylalanine and Encephalitis Lethargica Type Parkinsonism

ArticleYear
L-dopa in postencephalitic parkinsonism.
    Lancet (London, England), 1969, Apr-12, Volume: 1, Issue:7598

    Topics: Aged; Athetosis; Chorea; Clinical Trials as Topic; Delusions; Dihydroxyphenylalanine; Female; Humans

1969
L-dopa in idiopathic parkinsonism.
    Lancet (London, England), 1969, Nov-08, Volume: 2, Issue:7628

    Topics: Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Hypotension, Orthostatic; Mental Disorders

1969
Combined treatment of parkinsonism with L-dopa and amantadine.
    Lancet (London, England), 1970, Aug-22, Volume: 2, Issue:7669

    Topics: Aged; Amantadine; Chorea; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Hypotens

1970
[Treatment of Parkinsonic syndrome with levo-Dopa. Case reports].
    Minerva medica, 1974, May-02, Volume: 65, Issue:33

    Topics: Arteriosclerosis; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Female; Humans;

1974
A double blind study of 1-dopa treatment in Parkinson's disease.
    European neurology, 1968, Volume: 1, Issue:3

    Topics: Blood Pressure; Clinical Trials as Topic; Dihydroxyphenylalanine; Extrapyramidal Tracts; Female; Hum

1968
[Results of two new drugs in Parkinson's disease: L-dopa and amantadine].
    Revue neurologique, 1970, Volume: 122, Issue:2

    Topics: Adult; Aged; Amantadine; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Middle Aged; Park

1970
[L-Dopa therapy in Parkinson's disease. A double-blind study].
    Ugeskrift for laeger, 1971, Nov-26, Volume: 133, Issue:47

    Topics: Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Na

1971
The clinical use of levodopa in the treatment of Parkinson's disease.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Acute Disease; Adult; Age Factors; Aged; Antiparkinson Agents; California; Clinical Trials as Topic;

1971

Other Studies

42 other studies available for dihydroxyphenylalanine and Encephalitis Lethargica Type Parkinsonism

ArticleYear
FDG- and Dopa-PET in postencephalitic parkinsonism.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:11

    Topics: Aged; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Magne

2000
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:12

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans;

1977
[Catecholamine excretion and treatment of parkinsonism with midantan].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:9

    Topics: Adult; Aged; Amantadine; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Huma

1976
Levodopa in postencephalitic parkinsonism.
    Lancet (London, England), 1970, Dec-26, Volume: 2, Issue:7687

    Topics: Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Disorders; Parkinson Disease, Postencepha

1970
[Study of L-dopa treatment and its principal side effects in aged subjects].
    Gerontologia clinica, 1972, Volume: 14, Issue:5

    Topics: Aged; Antidepressive Agents; Asthenia; Cardiovascular Diseases; Circadian Rhythm; Dihydroxyphenylala

1972
DOPA in Parkinson's disease.
    Lancet (London, England), 1969, Apr-26, Volume: 1, Issue:7600

    Topics: Animals; Dihydroxyphenylalanine; Humans; Methyldopa; Parkinson Disease; Parkinson Disease, Postencep

1969
Incontinent nostalgia induced by L-dopa.
    Lancet (London, England), 1970, Jun-27, Volume: 1, Issue:7661

    Topics: Dihydroxyphenylalanine; Female; Humans; Libido; Memory; Middle Aged; Parkinson Disease, Postencephal

1970
Side-effects of L-dopa in postencephalitic parkinsonism.
    Lancet (London, England), 1970, Sep-26, Volume: 2, Issue:7674

    Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Myoclonus; Parkinson Disease, Postencep

1970
[Homovanillic acid in the cerebrospinal fluid: studies in Parkinson's syndrome and other diseases of the CNS].
    Wiener klinische Wochenschrift, 1966, Jun-10, Volume: 78, Issue:23

    Topics: Adult; Aged; Central Nervous System Diseases; Cerebrospinal Fluid; Dihydroxyphenylalanine; Epilepsy;

1966
[Specific therapy of extrapyramidal-motor syndromes].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform

1969
Treatment failures with L-dopa in Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Gastrointestinal Diseases; Humans; Intracranial Arterio

1972
Long-term treatment of Parkinsonism with L-dopa.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Parkinson

1972
Surgical treatment, past and present, in Parkinson's disease.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Adult; Aged; Brain; Cordotomy; Dihydroxyphenylalanine; Electrocoagulation; Female; Functional Latera

1972
L-dopa in the treatment of parkinsonism.
    Gerontologia clinica, 1972, Volume: 14, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Arteriosclerosis; Aspartate Aminotransferases; Blood Urea Nitrogen; Dihy

1972
Hypersexual behavior complicating levodopa (I-dopa) therapy.
    Minnesota medicine, 1973, Volume: 56, Issue:1

    Topics: Aged; Dihydroxyphenylalanine; Erectile Dysfunction; Humans; Male; Mental Disorders; Parkinson Diseas

1973
Cerebrospinal fluid N-acetyl neuraminic acid in Parkinson's disease, before and after L-dopa therapy.
    Diseases of the nervous system, 1973, Volume: 34, Issue:1

    Topics: Age Factors; Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Neuraminic Acids; Park

1973
Brain acetylcholinesterase in Parkinson's disease.
    Acta neurologica Scandinavica, 1973, Volume: 49, Issue:2

    Topics: Acetylcholinesterase; Aged; Autolysis; Autopsy; Basal Ganglia; Brain; Caudate Nucleus; Cerebellar Co

1973
[Quantitative testing methods for objectification of the effect of prolonged L-dopa therapy in parkinsonism].
    Der Nervenarzt, 1973, Volume: 44, Issue:8

    Topics: Adult; Aged; Akinetic Mutism; Dihydroxyphenylalanine; Female; Humans; Intracranial Arteriosclerosis;

1973
[Correlation of biochemical findings and the state of the neuromuscular apparatus in patients with parkinsonism during use of decimeter wave therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Electromagnetic Phenomena; Electromyography; Epinephr

1973
[The Rorschach test in parkinsonian patients. Its course during treatment with L dopa. Its prognostic value].
    Annales medico-psychologiques, 1973, Volume: 1, Issue:5

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Parkinson Disease; Parkinson

1973
Plasma concentration of levodopa in patients with Parkinson's disease.
    European neurology, 1973, Volume: 10, Issue:5

    Topics: Administration, Oral; Adult; Aged; Benserazide; Dihydroxyphenylalanine; Drug Combinations; Female; H

1973
[Treatment of parkinsonism with the drug L-DOPA].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Brain Diseases; Dihydroxyphenylalanine; Hepatolenticular Degeneration; Humans; Movement Disorders; P

1973
Neurofibrillary tangles in progressive supranuclear palsy. Electron microscopic observations.
    Journal of neuropathology and experimental neurology, 1974, Volume: 33, Issue:1

    Topics: Aged; Amantadine; Brain; Brain Diseases; Bulbar Palsy, Progressive; Dementia; Dihydroxyphenylalanine

1974
Parkinson's disease: a clinical review.
    The American journal of the medical sciences, 1974, Volume: 267, Issue:2

    Topics: Adult; Aged; Brain Diseases; Bulbar Palsy, Progressive; Dementia; Diagnosis, Differential; Dihydroxy

1974
Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:4

    Topics: Aged; Amantadine; Cognition Disorders; Dihydroxyphenylalanine; Drug Therapy, Combination; Edema; Eye

1974
Periodicity of speech in Parkinsonism.
    Nature, 1971, Jun-04, Volume: 231, Issue:5301

    Topics: Adult; Aged; Basal Ganglia; Dihydroxyphenylalanine; Feedback; Humans; Kinesthesis; Middle Aged; Park

1971
[The treatment of Parkinson's disease with levodopa. Principles. Practical advice. Considerations].
    La Nouvelle presse medicale, 1972, Mar-04, Volume: 1, Issue:10

    Topics: Amantadine; Dihydroxyphenylalanine; Drug Combinations; Drug Interactions; Drug Tolerance; Female; Ho

1972
Response of patients with postencephalitic Parkinsonism to levodopa.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:4

    Topics: Aged; Dihydroxyphenylalanine; Encephalitis; Evaluation Studies as Topic; Female; Humans; Hypotension

1972
A year's experience of L-DOPA in the treatment of Parkinson's disease.
    Acta neurochirurgica, 1971, Volume: 24, Issue:2

    Topics: Adult; Age Factors; Aged; Dihydroxyphenylalanine; Female; Functional Laterality; Humans; Hypotension

1971
[Treatment of the Parkinson syndrome with amantadine].
    Schweizerische medizinische Wochenschrift, 1971, Dec-04, Volume: 101, Issue:48

    Topics: Adult; Aged; Amantadine; Arteriosclerosis; Cognition Disorders; Dihydroxyphenylalanine; Drug Interac

1971
Parkinsonism and dopa.
    The New Zealand medical journal, 1969, Volume: 69, Issue:444

    Topics: Dihydroxyphenylalanine; Humans; New Zealand; Orphenadrine; Parkinson Disease; Parkinson Disease, Pos

1969
Abnormal mouth-movements and oral damage associated with L-DOPA treatment.
    Annals of dentistry, 1970,Winter, Volume: 29, Issue:4

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Oral Manifestations; Parkins

1970
Parkinsonism.
    British medical journal, 1969, Nov-29, Volume: 4, Issue:5682

    Topics: Agranulocytosis; Dihydroxyphenylalanine; Humans; Middle Aged; Nausea; Orphenadrine; Parasympatholyti

1969
Reversal of the glabellar reflex in Parkinsonism by L-dopa.
    Journal of neurology, neurosurgery, and psychiatry, 1969, Volume: 32, Issue:5

    Topics: Adult; Aged; Brain Diseases; Dihydroxyphenylalanine; Humans; Middle Aged; Parkinson Disease; Parkins

1969
[Our experience in the treatment of the parkinsonian syndrome with L-dopa. I. Evaluation of the clinical results].
    Rivista di patologia nervosa e mentale, 1969, Volume: 90, Issue:5

    Topics: Dihydroxyphenylalanine; Humans; Intracranial Arteriosclerosis; Parkinson Disease; Parkinson Disease,

1969
[The treatment of Parkinson's syndrome with L-dopa].
    Der Nervenarzt, 1970, Volume: 41, Issue:3

    Topics: Dihydroxyphenylalanine; Disability Evaluation; Female; Humans; Male; Middle Aged; Parkinson Disease;

1970
Psychosis and other psychiatric manifestations of levodopa therapy.
    Archives of neurology, 1970, Volume: 23, Issue:3

    Topics: Adult; Aged; Anxiety; Depression; Dihydroxyphenylalanine; Euphoria; Female; Humans; Male; Middle Age

1970
Long-term effects of levodopa in the severely disabled patient.
    JAMA, 1970, Sep-28, Volume: 213, Issue:13

    Topics: Chorea; Dihydroxyphenylalanine; Female; Humans; Male; Movement Disorders; Parkinson Disease; Parkins

1970
L-dopa for postencephalitic Parkinsonism.
    British medical journal, 1970, Nov-21, Volume: 4, Issue:5733

    Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Nausea; Parkinson Disea

1970
[Psychic manifestations during treatment of Parkinson's disease with L-dopa].
    Revue neurologique, 1970, Volume: 122, Issue:2

    Topics: Dihydroxyphenylalanine; Humans; Mental Disorders; Parkinson Disease; Parkinson Disease, Postencephal

1970
Treatment of Parkinson's disease with L-dopa: a current appraisal.
    Canadian Medical Association journal, 1971, Mar-20, Volume: 104, Issue:6

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Dihydroxyphenylalanine; Follow-Up Studies; Humans; Male; M

1971
Treatment of parkinsonism with levodopa.
    Archives of neurology, 1969, Volume: 21, Issue:4

    Topics: Adult; Aged; Anorexia Nervosa; Arrhythmias, Cardiac; Dihydroxyphenylalanine; Female; Gait; Humans; H

1969