dihydroxyphenylalanine has been researched along with Dystonic Disorders in 13 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Dystonic Disorders: Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.
| Excerpt | Relevance | Reference |
|---|---|---|
| " By dosage analysis, we were able to detect a mutation in all patients." | 1.36 | High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia. ( Chang, HC; Chen, RS; Huang, CC; Huang, CL; Lai, SC; Lin, JJ; Lu, CS; Wang, CY; Weng, YH; Wu-Chou, YH; Yeh, TH, 2010) |
| "strictly defined dopa-responsive dystonia." | 1.31 | Gene mutation in hereditary progressive dystonia with marked diurnal fluctuation (HPD), strictly defined dopa-responsive dystonia. ( Hagiwara, H; Kakimoto, S; Nishiyama, N; Nomura, Y; Segawa, M; Yukishita, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (69.23) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, C | 2 |
| Shi, W | 1 |
| Zeng, Z | 1 |
| Zhang, M | 1 |
| Ling, C | 1 |
| Chen, L | 1 |
| Zhang, B | 1 |
| Li, WD | 1 |
| Akiyama, T | 1 |
| Hayashi, Y | 1 |
| Hanaoka, Y | 1 |
| Shibata, T | 1 |
| Akiyama, M | 1 |
| Nakamura, K | 1 |
| Tsuyusaki, Y | 1 |
| Kubota, M | 1 |
| Yoshinaga, H | 1 |
| Kobayashi, K | 1 |
| Bobylova, MIu | 1 |
| Mikhaĭlova, SB | 1 |
| Grinio, LP | 1 |
| Wu-Chou, YH | 1 |
| Yeh, TH | 1 |
| Wang, CY | 1 |
| Lin, JJ | 1 |
| Huang, CC | 1 |
| Chang, HC | 1 |
| Lai, SC | 1 |
| Chen, RS | 1 |
| Weng, YH | 1 |
| Huang, CL | 1 |
| Lu, CS | 1 |
| Bertram, KL | 1 |
| Williams, DR | 1 |
| Furukawa, Y | 2 |
| Guttman, M | 1 |
| Wong, H | 1 |
| Farrell, SA | 1 |
| Furtado, S | 1 |
| Kish, SJ | 1 |
| Grötzsch, H | 1 |
| Schnorf, H | 1 |
| Morris, MA | 1 |
| Moix, I | 1 |
| Horvath, J | 1 |
| Prilipko, O | 1 |
| Burkhard, PR | 1 |
| Kang, JH | 1 |
| Kang, SY | 1 |
| Kang, HK | 1 |
| Koh, YS | 1 |
| Im, JH | 1 |
| Lee, MC | 1 |
| Casseron, W | 1 |
| Genton, P | 1 |
| Hui xie, H | 1 |
| Wu, ZY | 1 |
| Wang, N | 1 |
| Murong, SX | 1 |
| Asanuma, K | 1 |
| Carbon-Correll, M | 1 |
| Eidelberg, D | 1 |
| Nishiyama, N | 1 |
| Yukishita, S | 1 |
| Hagiwara, H | 1 |
| Kakimoto, S | 1 |
| Nomura, Y | 1 |
| Segawa, M | 1 |
2 reviews available for dihydroxyphenylalanine and Dystonic Disorders
| Article | Year |
|---|---|
[DOPA-responsive dystonia (Segawa's disease)].
Topics: Dihydroxyphenylalanine; Dopamine Agents; Dystonic Disorders; Humans; Parkinson Disease; Substance-Re | 2009 |
Diagnosis of dystonic syndromes--a new eight-question approach.
Topics: Age of Onset; Brain; Dihydroxyphenylalanine; Dystonic Disorders; Hepatolenticular Degeneration; Huma | 2012 |
11 other studies available for dihydroxyphenylalanine and Dystonic Disorders
| Article | Year |
|---|---|
GTP cyclohydrolase I and tyrosine hydroxylase gene mutations in familial and sporadic dopa-responsive dystonia patients.
Topics: Adult; Aged; Asian People; Dihydroxyphenylalanine; DNA Mutational Analysis; Dystonic Disorders; Exon | 2013 |
Simultaneous measurement of monoamine metabolites and 5-methyltetrahydrofolate in the cerebrospinal fluid of children.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; | 2017 |
High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia.
Topics: Adult; Asian People; Case-Control Studies; Cohort Studies; Dihydroxyphenylalanine; Dystonia; Dystoni | 2010 |
Genetics and biochemistry of dopa-responsive dystonia: significance of striatal tyrosine hydroxylase protein loss.
Topics: Animals; Biopterins; Dihydroxyphenylalanine; Dopamine; Dystonic Disorders; GTP Cyclohydrolase; Homov | 2003 |
Serum prolactin in symptomatic and asymptomatic dopa-responsive dystonia due to a GCH1 mutation.
Topics: Amino Acid Substitution; Dihydroxyphenylalanine; Dystonic Disorders; Exons; Female; Genes, Dominant; | 2003 |
Phenotypic heterogeneity of dopa-responsive dystonia in monozygotic twins.
Topics: Adult; Benserazide; Biopterins; Clubfoot; Dihydroxyphenylalanine; Disease Progression; Diseases in T | 2004 |
A novel missense mutation of the GTP cyclohydrolase I gene in a Korean family with hereditary progressive dystonia/dopa-responsive dystonia.
Topics: Adolescent; Child; Child, Preschool; Dihydroxyphenylalanine; DNA Mutational Analysis; Dopamine Agent | 2004 |
DOPA-sensitive dystonia-plus syndrome.
Topics: Adolescent; Benserazide; Brain; Child; Child Behavior Disorders; Child, Preschool; Craniofacial Abno | 2005 |
Gene symbol: GTP cyclohydrolase I (GCH-I). Disease: dopa-responsive dystonia.
Topics: Amino Acid Substitution; Dihydroxyphenylalanine; Dystonic Disorders; GTP Cyclohydrolase; Humans; Mut | 2005 |
Neuroimaging in human dystonia.
Topics: Anisotropy; Basal Ganglia; Blepharospasm; Carbon Radioisotopes; Case-Control Studies; Dihydroxypheny | 2005 |
Gene mutation in hereditary progressive dystonia with marked diurnal fluctuation (HPD), strictly defined dopa-responsive dystonia.
Topics: Dihydroxyphenylalanine; DNA Mutational Analysis; Dystonia; Dystonic Disorders; Exons; Female; GTP Cy | 2000 |