Page last updated: 2024-10-18

dihydroxyphenylalanine and Disease Models, Animal

dihydroxyphenylalanine has been researched along with Disease Models, Animal in 87 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The administration of catechol-O-methyltransferase inhibitors alone changed neither the behavior of the rats in two animal models of depression, the forced swimming test (entacapone and tolcapone) or in the learned helplessness paradigm (tolcapone), nor the locomotor activity."7.69Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression. ( Lang, A; Männistö, PT; Rauhala, P; Vasar, E, 1995)
"To investigate the involvement of oxidative tissue damage in the pathogenesis of murine cerebral malaria (CM), brain levels of protein carbonyls, 3,4-dihydroxyphenylalanine (DOPA), o-tyrosine, and dityrosine were measured during Plasmodium berghei ANKA (PbA) and P."3.70Are reactive oxygen species involved in the pathogenesis of murine cerebral malaria? ( Bloomfield, G; Chaudhri, G; Dean, RT; Dinauer, MC; Fu, S; Hunt, NH; Sanni, LA; Stocker, R, 1999)
"The administration of catechol-O-methyltransferase inhibitors alone changed neither the behavior of the rats in two animal models of depression, the forced swimming test (entacapone and tolcapone) or in the learned helplessness paradigm (tolcapone), nor the locomotor activity."3.69Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression. ( Lang, A; Männistö, PT; Rauhala, P; Vasar, E, 1995)
"In cancer patients with hypersplenism-related thrombocytopenia, PSAE is a safe intervention that effects a durable elevation in platelet counts across a range of malignancies and following the re-initiation of chemotherapy."2.73 ( Aasbrenn, M; Abd El-Aty, AM; Abdu, A; Abraha, HB; Achour, A; Acquaroni, M; Addeo, P; Agback, P; Agback, T; Al-Alwan, M; Al-Mazrou, A; Al-Mohanna, F; Aliste, M; Almquist, J; Andel, J; Ando, M; Angelov, A; Annuar, MSM; Antwi, K; Arroliga, AC; Arruda, SLM; Asch, SM; Averous, G; Ayaz, S; Ayer, GB; Bachellier, P; Ball, S; Banijamali, AR; Barden, TC; Bartoncini, S; Bedanie, G; Bellò, M; Benić, F; Berhe, GG; Bertiger, G; Beumer, JH; Bhandari, B; Bond, DS; Boules, M; Braüner Christensen, J; Brown-Johnson, C; Burgstaller, S; Cao, L; Capasso, C; Carlevato, R; Carvalho, AE; Ceci, F; Chagas, ATA; Chavan, SG; Chen, AP; Chen, HC; Chen, J; Chen, Q; Chen, Y; Chen, YF; Christ, ER; Chu, CW; Covey, JM; Coyne, GO'; Cristea, MC; Currie, MG; Dahdal, DN; Dai, L; Dang, Z; de Abreu, NL; de Carvalho, KMB; de la Plaza Llamas, R; Deandreis, D; Del Prete, S; Dennis, JA; Deur, J; Díaz Candelas, DA; Divyapriya, G; Djanani, A; Dodig, D; Doki, Y; Doroshow, JH; Dos Santos, RC; Durairaj, N; Dutra, ES; Eguchi, H; Eisterer, W; Ekmann, A; Elakkad, A; Evans, WE; Fan, W; Fang, Z; Faria, HP; Farris, SG; Fenoll, J; Fernandez-Botran, R; Flores, P; Fujita, J; Gan, L; Gandara, DR; Gao, X; Garcia, AA; Garrido, I; Gebru, HA; Gerger, A; Germano, P; Ghamande, S; Ghebeh, H; Giver Jensen, T; Go, A; Goichot, B; Goldwater, M; Gontero, P; Greil, R; Gruenberger, B; Guarneri, A; Guo, Y; Gupta, S; Haxholdt Lunn, T; Hayek, AJ; He, ML; Hellín, P; Hepprich, M; Hernández de Rodas, E; Hill, A; Hndeya, AG; Holdsworth, LM; Hookey, L; Howie, W; Hu, G; Huang, JD; Huang, SY; Hubmann, E; Hwang, SY; Imamura, H; Imperiale, A; Jiang, JQ; Jimenez, JL; Jin, F; Jin, H; Johnson, KL; Joseph, A; Juwara, L; Kalapothakis, E; Karami, H; Karayağiz Muslu, G; Kawabata, R; Kerwin, J; Khan, I; Khin, S; Kidanemariam, HG; Kinders, RJ; Klepov, VV; Koehler, S; Korger, M; Kovačić, S; Koyappayil, A; Kroll, MH; Kuban, J; Kummar, S; Kung, HF; Kurokawa, Y; Laengle, F; Lan, J; Leal, HG; Lee, MH; Lemos, KGE; Li, B; Li, G; Li, H; Li, X; Li, Y; Li, Z; Liebl, W; Lillaz, B; Lin, F; Lin, L; Lin, MCM; Lin, Y; Lin, YP; Lipton, RB; Liu, J; Liu, W; Liu, Z; Lu, J; Lu, LY; Lu, YJ; Ludwig, S; Luo, Y; Ma, L; Ma, W; Machado-Coelho, GLL; Mahmoodi, B; Mahoney, M; Mahvash, A; Mansour, FA; Mao, X; Marinho, CC; Masferrer, JL; Matana Kaštelan, Z; Melendez-Araújo, MS; Méndez-Chacón, E; Miletić, D; Miller, B; Miller, E; Miller, SB; Mo, L; Moazzen, M; Mohammadniaei, M; Montaz-Rosset, MS; Mousavi Khaneghah, A; Mühlethaler, K; Mukhopadhyay, S; Mulugeta, A; Nambi, IM; Navarro, S; Nazmara, S; Neumann, HJ; Newman, EM; Nguyen, HTT; Nicolato, AJPG; Nicolotti, DG; Nieva, JJ; Nilvebrant, J; Nocentini, A; Nugent, K; Nunez-Rodriguez, DL; Nygren, PÅ; Oberli, A; Oderda, M; Odisio, B; Oehler, L; Otludil, B; Overman, M; Özdemir, M; Pace, KA; Palm, H; Parchment, RE; Parise, R; Passera, R; Pavlovic, J; Pecherstorfer, M; Peng, Z; Pérez Coll, C; Petzer, A; Philipp-Abbrederis, K; Pichler, P; Piekarz, RL; Pilati, E; Pimentel, JDSM; Posch, F; Prager, G; Pressel, E; Profy, AT; Qi, P; Qi, Y; Qiu, C; Rajasekhar, B; Ramia, JM; Raynor, HA; Reis, VW; Reubi, JC; Ricardi, U; Riedl, JM; Romano, F; Rong, X; Rubinstein, L; Rumboldt, Z; Sabir, S; Safaeinili, N; Sala, BM; Sandoval Castillo, L; Sau, M; Sbhatu, DB; Schulte, T; Scott, V; Shan, H; Shao, Y; Shariatifar, N; Shaw, JG; She, Y; Shen, B; Shernyukov, A; Sheth, RA; Shi, B; Shi, R; Shum, KT; Silva, JC; Singh, A; Sinha, N; Sirajudeen, AAO; Slaven, J; Sliwa, T; Somme, F; Song, S; Steinberg, SM; Subramaniam, R; Suetta, C; Sui, Y; Sun, B; Sun, C; Sun, H; Sun, Y; Supuran, CT; Surger, M; Svartz, G; Takahashi, T; Takeno, A; Tam, AL; Tang, Z; Tanner, JA; Tannich, E; Taye, MG; Tekle, HT; Thomas, GJ; Tian, Y; Tobin, JV; Todd Milne, G; Tong, X; Une, C; Vela, N; Venkateshwaran, U; Villagrán de Tercero, CI; Wakefield, JD; Wampfler, R; Wan, M; Wang, C; Wang, J; Wang, L; Wang, S; Waser, B; Watt, RM; Wei, B; Wei, L; Weldemichael, MY; Wellmann, IA; Wen, A; Wild, D; Wilthoner, K; Winder, T; Wing, RR; Winget, M; Wöll, E; Wong, KL; Wong, KT; Wu, D; Wu, Q; Wu, Y; Xiang, T; Xiang, Z; Xu, F; Xu, L; Yamasaki, M; Yamashita, K; Yan, H; Yan, Y; Yang, C; Yang, H; Yang, J; Yang, N; Yang, Y; Yau, P; Yu, M; Yuan, Q; Zhan, S; Zhang, B; Zhang, H; Zhang, J; Zhang, N; Zhang, Y; Zhao, X; Zheng, BJ; Zheng, H; Zheng, W; Zhou, H; Zhou, X; Zhu, S; Zimmer, DP; Zionts, D; Zitella, A; Zlott, J; Zolfaghari, K; Zuo, D; Zur Loye, HC; Žuža, I, 2007)
" Animals received repeated dosing of either hUCB-derived plasma or vehicle at 3, 5 and 10 days after induction into MPTP lesion, then behaviourally and immunohistochemically evaluated over 56 days post-lesion."1.51Gutting the brain of inflammation: A key role of gut microbiome in human umbilical cord blood plasma therapy in Parkinson's disease model. ( Borlongan, CV; Ehrhart, J; Lee, JY; Sanberg, PR; Tuazon, JP, 2019)
"The selective VTA DAergic neuron degeneration results in lower DA outflow in the hippocampus and nucleus accumbens (NAc) shell."1.46Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease. ( Aversa, D; Berretta, N; Cavallucci, V; Coccurello, R; Cordella, A; Cutuli, D; D'Amelio, M; De Bartolo, P; Dell'Acqua, MC; Federici, M; Giacovazzo, G; Keller, F; Krashia, P; Latagliata, EC; Marino, R; Mercuri, NB; Nobili, A; Petrosini, L; Puglisi-Allegra, S; Rizzo, FR; Sancandi, M; Viscomi, MT, 2017)
" The loaded gel was administered in different doses and dosing regimens to Parkinsonian rats, and the catalepsy score and striatal DA levels were assessed."1.42Potential efficacy of dopamine loaded-PVP/PAA nanogel in experimental models of Parkinsonism: possible disease modifying activity. ( Abd El-Rehim, HA; El-Ghazaly, MA; Rashed, ER, 2015)
"Conventional symptomatic treatment for Parkinson's disease (PD) with long-term L-3,4-dihydroxyphenylalanine (DOPA) is complicated with development of drug-induced side effects."1.42Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease. ( Broom, L; Cederfjäll, E; Kirik, D, 2015)
" The long-term use of LD is limited by the development of L-DOPA-induced dyskinesias and dystonia."1.39The combination of oral L-DOPA/rimonabant for effective dyskinesia treatment and cytological preservation in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia. ( Aley-Medina, P; Anaya-Martínez, V; Avila-Costa, MR; Espinosa-Villanueva, J; García-Ruiz, R; Gutiérrez-Valdez, AL; Montiel-Flores, E; Reynoso-Erazo, L; Sánchez-Betancourt, J; Torres-Esquivel, C; Tron-Alvarez, R, 2013)
" The stronger in vivo effect of (+)-catechin on L-DOPA methylation compared to the other dietary compounds is due to its better bioavailability in vivo."1.39Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration. ( Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT, 2013)
" Study of pharmacokinetic parameters (AUC, C(max), and T(max)) revealed a greater and more extended release of ropinirole from nanoemulsion gel compared to that from a conventional gel (RPG) and oral marketed tablet (Ropitor)."1.38Oil based nanocarrier system for transdermal delivery of ropinirole: a mechanistic, pharmacokinetic and biochemical investigation. ( Ahmad, FJ; Azeem, A; Iqbal, Z; Khar, RK; Negi, LM; Talegaonkar, S, 2012)
"Heatstroke was induced by exposing the anesthetized rabbits to a high blanket temperature (T(blanket)) of 45 degrees C."1.33Dopamine overload visualized in the basal ganglia of rabbit brain during heatstroke can be suppressed by hypothermia. ( Chang, CW; Chen, JC; Chou, KL; Chou, YT; Lin, MT; Liu, RS, 2005)
"Parkinsonism was induced using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine."1.32Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys. ( Bezard, E; Di Monte, DA; Hsu, A; Langston, JW; Quik, M; Sokoloff, P; Togasaki, DM, 2004)
"In monkeys with resting tremor, the administration of DL-5-HTP (5-hydroxytryptophan) or of DL-DOPA (3,4-dihydroxyphenylalanine) relieves the tremor, but the simultaneous administration of DL-5-HTP or DL-DOPA and atropine results in a much more pronounced relief."1.25The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions. ( Anagnoste, B; Battista, AF; Goldstein, M; Nakatani, S, 1969)

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199039 (44.83)18.7374
1990's10 (11.49)18.2507
2000's14 (16.09)29.6817
2010's20 (22.99)24.3611
2020's4 (4.60)2.80

Authors

AuthorsStudies
de Matos Balsalobre, N1
Dos Santos, E1
Mariano Dos Santos, S1
Arena, AC1
Konkiewitz, EC1
Ziff, EB1
Nazari Formagio, AS1
Leite Kassuya, CA1
Song, C1
Zhang, X1
Wang, L3
Wen, F1
Xu, K1
Xiong, W1
Li, C1
Li, B2
Wang, Q1
Xing, MMQ1
Qiu, X1
Yang, N1
Tanner, JA1
Zheng, BJ1
Watt, RM1
He, ML1
Lu, LY1
Jiang, JQ1
Shum, KT1
Lin, YP1
Wong, KL1
Lin, MCM1
Kung, HF1
Sun, H1
Huang, JD1
Marinho, CC1
Nicolato, AJPG1
Reis, VW1
Dos Santos, RC1
Silva, JC1
Faria, HP1
Machado-Coelho, GLL1
Sun, Y2
Zhang, N1
Wang, J3
Guo, Y1
Sun, B1
Liu, W1
Zhou, H1
Yang, C1
Wei, L1
Ball, S1
Dennis, JA1
Bedanie, G1
Nugent, K1
Hayek, AJ1
Scott, V1
Yau, P1
Zolfaghari, K1
Goldwater, M1
Almquist, J1
Arroliga, AC1
Ghamande, S1
Wu, Q1
Ma, W1
Shi, R1
Zhang, B1
Mao, X1
Zheng, W1
Sbhatu, DB1
Berhe, GG1
Hndeya, AG1
Abraha, HB1
Abdu, A1
Gebru, HA1
Taye, MG1
Mulugeta, A1
Weldemichael, MY1
Tekle, HT1
Kidanemariam, HG1
Surger, M1
Angelov, A1
Liebl, W1
Hookey, L1
Bertiger, G1
Johnson, KL1
Boules, M1
Ando, M1
Dahdal, DN1
Riedl, JM1
Posch, F1
Prager, G1
Eisterer, W1
Oehler, L1
Sliwa, T1
Wilthoner, K1
Petzer, A1
Pichler, P1
Hubmann, E1
Winder, T1
Burgstaller, S1
Korger, M1
Andel, J1
Greil, R1
Neumann, HJ1
Pecherstorfer, M1
Philipp-Abbrederis, K1
Djanani, A1
Gruenberger, B1
Laengle, F1
Wöll, E1
Gerger, A1
Evans, WE1
Raynor, HA1
Howie, W1
Lipton, RB1
Thomas, GJ1
Wing, RR1
Pavlovic, J1
Farris, SG1
Bond, DS1
Hepprich, M1
Antwi, K1
Waser, B1
Reubi, JC1
Wild, D1
Christ, ER1
Braüner Christensen, J1
Aasbrenn, M1
Sandoval Castillo, L1
Ekmann, A1
Giver Jensen, T1
Pressel, E1
Haxholdt Lunn, T1
Suetta, C1
Palm, H1
Mansour, FA1
Al-Mazrou, A1
Al-Mohanna, F1
Al-Alwan, M1
Ghebeh, H1
Brown-Johnson, C1
Safaeinili, N1
Zionts, D1
Holdsworth, LM1
Shaw, JG1
Asch, SM1
Mahoney, M1
Winget, M1
Luo, Y1
Shan, H1
Gao, X1
Qi, P1
Li, Y2
Rong, X1
Shen, B1
Zhang, H1
Lin, F1
Tang, Z1
Fang, Z1
Peng, Z1
Jimenez, JL1
Ayer, GB1
Klepov, VV1
Pace, KA1
Zur Loye, HC1
Acquaroni, M1
Svartz, G1
Pérez Coll, C1
Otludil, B1
Ayaz, S1
Hill, A1
Elakkad, A1
Kuban, J1
Sabir, S1
Odisio, B1
Huang, SY1
Mahvash, A1
Miller, E1
Kroll, MH1
Overman, M1
Tam, AL1
Gupta, S1
Sheth, RA1
Deandreis, D1
Guarneri, A1
Ceci, F1
Lillaz, B1
Bartoncini, S1
Oderda, M1
Nicolotti, DG1
Pilati, E1
Passera, R1
Zitella, A1
Bellò, M1
Parise, R1
Carlevato, R1
Ricardi, U1
Gontero, P1
Coyne, GO'1
Zlott, J1
Juwara, L1
Covey, JM1
Beumer, JH1
Cristea, MC1
Newman, EM1
Koehler, S1
Nieva, JJ1
Garcia, AA1
Gandara, DR1
Miller, B1
Khin, S1
Miller, SB1
Steinberg, SM1
Rubinstein, L1
Parchment, RE1
Kinders, RJ1
Piekarz, RL1
Kummar, S1
Chen, AP1
Doroshow, JH1
Li, X2
Chen, J2
Gan, L1
Tian, Y1
Shi, B1
Yang, Y1
Li, G1
Wu, D1
Wen, A1
Wu, Y1
Zhou, X1
Koyappayil, A1
Chavan, SG1
Mohammadniaei, M1
Go, A1
Hwang, SY1
Lee, MH1
Kurokawa, Y1
Yamashita, K1
Kawabata, R1
Fujita, J1
Imamura, H1
Takeno, A1
Takahashi, T1
Yamasaki, M1
Eguchi, H1
Doki, Y1
Schulte, T1
Sala, BM1
Nilvebrant, J1
Nygren, PÅ1
Achour, A1
Shernyukov, A1
Agback, T1
Agback, P1
Karami, H1
Shariatifar, N1
Nazmara, S1
Moazzen, M1
Mahmoodi, B1
Mousavi Khaneghah, A1
Sinha, N1
Mukhopadhyay, S1
Sau, M1
Qi, Y1
Wan, M1
Abd El-Aty, AM1
Li, H2
Cao, L1
She, Y1
Shao, Y1
Jin, F1
Wang, S1
Melendez-Araújo, MS1
Lemos, KGE1
Arruda, SLM1
Dutra, ES1
de Carvalho, KMB1
de la Plaza Llamas, R1
Díaz Candelas, DA1
Ramia, JM1
Zhu, S1
Liu, Z2
Lu, J2
Xiang, Z1
Lan, J1
Liu, J2
Yu, M1
Chen, Y2
Sirajudeen, AAO1
Annuar, MSM1
Subramaniam, R1
Somme, F1
Montaz-Rosset, MS1
Averous, G1
Deur, J1
Goichot, B1
Bachellier, P1
Addeo, P1
Imperiale, A1
Xu, L1
Li, Z2
Song, S1
Chen, Q1
Mo, L1
Wang, C1
Fan, W1
Yan, Y1
Tong, X1
Yan, H1
Singh, A1
Chen, HC1
Chen, YF1
Lu, YJ1
Wong, KT1
Chu, CW1
Banijamali, AR1
Carvalho, AE1
Wakefield, JD1
Germano, P1
Barden, TC1
Tobin, JV1
Zimmer, DP1
Masferrer, JL1
Profy, AT1
Currie, MG1
Todd Milne, G1
Zhang, Y1
Yang, H1
Dang, Z1
Zhan, S1
Sun, C1
Hu, G1
Lin, Y1
Yuan, Q1
Karayağiz Muslu, G1
Özdemir, M1
Del Prete, S1
Nocentini, A1
Supuran, CT1
Capasso, C1
Chagas, ATA1
Ludwig, S1
Pimentel, JDSM1
de Abreu, NL1
Nunez-Rodriguez, DL1
Leal, HG1
Kalapothakis, E1
Zhang, J1
Lin, L1
Dodig, D1
Kovačić, S1
Matana Kaštelan, Z1
Žuža, I1
Benić, F1
Slaven, J1
Miletić, D1
Rumboldt, Z1
Fernandez-Botran, R1
Wellmann, IA1
Une, C1
Méndez-Chacón, E1
Hernández de Rodas, E1
Bhandari, B1
Villagrán de Tercero, CI1
Nguyen, HTT1
Romano, F1
Wampfler, R1
Mühlethaler, K1
Tannich, E1
Oberli, A1
Yang, J1
Xiang, T1
Dai, L1
Zhao, X1
Ma, L1
Zuo, D1
Wei, B1
Sui, Y1
Xu, F1
Zheng, H1
Qiu, C1
Jin, H1
Kerwin, J1
Khan, I1
Rajasekhar, B1
Venkateshwaran, U1
Durairaj, N1
Divyapriya, G1
Nambi, IM1
Joseph, A1
Aliste, M1
Garrido, I1
Flores, P1
Hellín, P1
Vela, N1
Navarro, S1
Fenoll, J1
Liu, H1
Zhao, Z1
Guo, D1
Liu, Y1
Speck, AE1
Aguiar, AS1
Ferreira, SG1
Silva, HB1
Tomé, ÂR1
Agostinho, P1
Cunha, RA1
Prediger, RD1
Guo, Q1
Wang, B1
Wang, X1
Smith, WW1
Zhu, Y1
Nobili, A1
Latagliata, EC1
Viscomi, MT1
Cavallucci, V1
Cutuli, D1
Giacovazzo, G1
Krashia, P1
Rizzo, FR1
Marino, R1
Federici, M1
De Bartolo, P1
Aversa, D1
Dell'Acqua, MC1
Cordella, A1
Sancandi, M1
Keller, F1
Petrosini, L1
Puglisi-Allegra, S1
Mercuri, NB1
Coccurello, R1
Berretta, N1
D'Amelio, M1
Oshima, G1
Guo, N1
He, C1
Stack, ME1
Poon, C1
Uppal, A1
Wightman, SC1
Parekh, A1
Skowron, KB1
Posner, MC1
Lin, W1
Khodarev, NN1
Weichselbaum, RR1
Pham, TT1
Nguyen, TT1
Pathak, S1
Regmi, S1
Nguyen, HT1
Tran, TH1
Yong, CS1
Kim, JO1
Park, PH1
Park, MH1
Bae, YK1
Choi, JU1
Byun, Y1
Ahn, CH1
Yook, S1
Jeong, JH1
Wu, J1
Zhao, YM1
Deng, ZK1
Chang, CW2
Yeh, CN1
Chung, YH1
Chen, YR1
Tien, SW1
Chen, TW1
Farn, SS1
Huang, YC1
Yu, CS1
Lee, JY1
Tuazon, JP1
Ehrhart, J1
Sanberg, PR1
Borlongan, CV1
Zhang, MZ1
Wang, Y1
Yao, B1
Gewin, L1
Wei, S1
Capdevila, JH1
Harris, RC1
Gutiérrez-Valdez, AL1
García-Ruiz, R1
Anaya-Martínez, V1
Torres-Esquivel, C1
Espinosa-Villanueva, J1
Reynoso-Erazo, L1
Tron-Alvarez, R1
Aley-Medina, P1
Sánchez-Betancourt, J1
Montiel-Flores, E1
Avila-Costa, MR1
Rashed, ER1
Abd El-Rehim, HA1
El-Ghazaly, MA1
Cederfjäll, E1
Broom, L1
Kirik, D1
Yanagisawa, D1
Oda, K1
Inden, M1
Morikawa, S1
Inubushi, T1
Taniguchi, T1
Hijioka, M1
Kitamura, Y1
Tooyama, I1
Becker, G1
Bahri, MA1
Michel, A1
Hustadt, F1
Garraux, G1
Luxen, A1
Lemaire, C1
Plenevaux, A1
Fan, X1
Xu, M1
Hess, EJ1
Kawada, H1
Kojima, M1
Kimura, T2
Natori, S1
Sasaki, K1
Sasaki, H1
Martiniova, L1
Lai, EW1
Thomasson, D1
Kiesewetter, DO1
Seidel, J1
Merino, MJ1
Kvetnansky, R1
Pacak, K1
Hiramoto, K1
Kobayashi, H1
Ishii, M1
Sato, E1
Inoue, M1
Yuan, J1
Darvas, M1
Sotak, B1
Hatzidimitriou, G1
McCann, UD1
Palmiter, RD1
Ricaurte, GA1
Domanskyi, A1
Geissler, C1
Vinnikov, IA1
Alter, H1
Schober, A1
Vogt, MA1
Gass, P1
Parlato, R1
Schütz, G1
Azeem, A1
Talegaonkar, S1
Negi, LM1
Ahmad, FJ1
Khar, RK1
Iqbal, Z1
Walker, MD1
Dinelle, K1
Kornelsen, R1
McCormick, S1
Mah, C1
Holden, JE2
Farrer, MJ1
Stoessl, AJ1
Sossi, V1
Kang, KS1
Yamabe, N1
Wen, Y1
Fukui, M1
Zhu, BT1
Forsback, S1
Niemi, R1
Marjamäki, P1
Eskola, O1
Bergman, J1
Grönroos, T1
Haaparanta, M1
Haapalinna, A1
Rinne, J1
Solin, O1
Hsu, A1
Togasaki, DM2
Bezard, E2
Sokoloff, P1
Langston, JW2
Di Monte, DA1
Quik, M1
Walter, B1
Brust, P1
Füchtner, F1
Müller, M1
Hinz, R1
Kuwabara, H1
Fritz, H1
Zwiener, U1
Bauer, R1
Doudet, DJ1
Cornfeldt, ML1
Honey, CR1
Schweikert, AW1
Allen, RC1
Chou, YT1
Chen, JC1
Liu, RS1
Chou, KL1
Lin, MT1
Sharma, SK1
El Refaey, H1
Ebadi, M1
Nagai, Y1
Obayashi, S1
Ando, K1
Inaji, M1
Maeda, J1
Okauchi, T1
Ito, H1
Suhara, T1
Gold, SJ1
Hoang, CV1
Potts, BW1
Porras, G1
Pioli, E1
Kim, KW1
Nadjar, A1
Qin, C1
LaHoste, GJ1
Li, Q1
Bioulac, BH1
Waugh, JL1
Gurevich, E1
Neve, RL1
Ivanov, AI1
Khitrov, NK1
Willner, P1
Efuni, SN1
Demurov, EA1
Koloskov, IuB1
Hefti, F1
Melamed, E1
Wurtman, RJ1
Hadesman, R1
Wiesner, RH1
Go, VL1
Tyce, GM1
Männistö, PT1
Lang, A1
Rauhala, P1
Vasar, E1
Slinkin, MA1
Curtet, C1
Faivre-Chauvet, A1
Sai-Maurel, C1
Gestin, JF1
Torchilin, VP1
Chatal, JF1
Lundberg, C2
Horellou, P2
Mallet, J2
Björklund, A2
Hume, SP1
Lammertsma, AA1
Myers, R1
Rajeswaran, S1
Bloomfield, PM1
Ashworth, S1
Fricker, RA1
Torres, EM1
Watson, I1
Jones, T1
Chakraborty, DP1
Roy, S1
Chakraborty, AK1
Leff, SE1
Rendahl, KG1
Spratt, SK1
Kang, UJ1
Mandel, RJ1
Sanni, LA1
Fu, S1
Dean, RT1
Bloomfield, G1
Stocker, R1
Chaudhri, G1
Dinauer, MC1
Hunt, NH1
Kordower, JH1
Emborg, ME1
Bloch, J1
Ma, SY1
Chu, Y1
Leventhal, L1
McBride, J1
Chen, EY1
Palfi, S1
Roitberg, BZ1
Brown, WD1
Pyzalski, R1
Taylor, MD1
Carvey, P1
Ling, Z1
Trono, D1
Hantraye, P1
Déglon, N1
Aebischer, P1
Hartmann, A1
Troadec, JD1
Hunot, S1
Kikly, K1
Faucheux, BA1
Mouatt-Prigent, A1
Ruberg, M1
Agid, Y1
Hirsch, EC1
Yee, RE1
Irwin, I1
Milonas, C1
Stout, DB1
Huang, SC1
Shoghi-Jadid, K1
Satyamurthy, N1
Delanney, LE1
Farahani, KF1
Delfani, K1
Janson, AM1
Phelps, ME1
Barrio, JR1
Loginov, VK1
Pogorelov, VN1
Le Bourdellès, B1
Wictorin, K1
Brundin, P1
Kalén, P1
Boissy, RE1
Moellmann, G1
Trainer, AT1
Smyth, JR1
Lerner, AB1
Chen, CS1
Shum, AY1
Hsu, SC1
Chen, CF1
Winter, R1
Nelson, SR1
Walaszek, EJ1
Lycke, E1
Roos, BE1
Burrous, SE1
Siedler, AJ1
Eudy, WW1
Mones, RJ1
Pasik, P1
Pasik, T1
Wilk, S1
Dumont, M1
Lamarre, Y1
Frigyesi, TL1
Yahr, MD1
Schwartz, R1
Anghileri, LJ1
Miller, ES1
Alousi, AA1
Beards, JA1
Snyder, SH1
Levin, SL1
Carlsson, A2
Goldstein, M5
Anagnoste, B4
Battista, AF5
Nakatani, S4
Ogawa, M2
McKenzie, GM1
Gordon, RJ1
Viik, K1
Plotnikoff, NP1
Kastin, AJ1
Anderson, MS1
Schally, AV1
Horst, WD1
Pool, WR1
Spiegel, HE1
Tret'iakova, KA1
Samoĭlova, ZT1
Osterholm, JL1
Mathews, GJ1
Irvin, JD1
Calesnick, B1
Stern, P1
Srebocan, S1
Cvetnić, S1
Brmalj, V1
Duvoisin, RC1
Marsden, CD1
Dollery, CT1
Davies, DS1
Lozano, JR1
Corday, E1
Carrasco, HA1
Lang, TW1
Meerbaum, S1
Hockman, CH1
Lloyd, KG1
Farley, IJ1
Hornykiewicz, O1
O-Ishi, S1
Sakuma, A1
Bergamini, L1
Bonzanino, O1
Brignolio, F1
Fabiani, A1
Fariello, R1
Mombelli, AM1
Mutani, R1
Pisani, W1
Postir, A1
Quattroccolo, G1
Riccio, A1
Sabbatini, F1
Sandigliano, G1
Schiffer, D1
Hornykiewicz, OD1
Whitnack, E1
Leff, A1
Mohammed, S1
Gaffney, TE1

Reviews

9 reviews available for dihydroxyphenylalanine and Disease Models, Animal

ArticleYear
The validity of animal models of depression.
    Psychopharmacology, 1984, Volume: 83, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Depressive Disorder;

1984
Studies on development of hairless descendants of Mexican hairless dogs and their usefulness in dermatological science.
    Experimental animals, 1996, Volume: 45, Issue:1

    Topics: Animals; Blood Cell Count; Breeding; Dermatitis, Allergic Contact; Dermatology; Dihydroxyphenylalani

1996
Vitiligo, psoralen, and melanogenesis: some observations and understanding.
    Pigment cell research, 1996, Volume: 9, Issue:3

    Topics: Animals; Dihydroxyphenylalanine; Disease Models, Animal; Furocoumarins; Humans; Indoles; Lead; Melan

1996
[Progress in leprology in recent years].
    Vestnik dermatologii i venerologii, 1975, Issue:9

    Topics: Animals; Dapsone; Dihydroxyphenylalanine; Disease Models, Animal; Humans; L-Lactate Dehydrogenase; L

1975
Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease.
    Journal de physiologie, 1991, Volume: 85, Issue:3

    Topics: Animals; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Genet

1991
Catecholamines in the brain as mediators of amphetamine psychosis.
    Archives of general psychiatry, 1972, Volume: 27, Issue:2

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain Chemistry; Bromides; Catecholamines; Cats; Cocain

1972
[Dopaminergic conception of Parkinsonism and its treatment with L-DOPA].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:9

    Topics: Acetylcholine; Animals; Basal Ganglia Diseases; Brain Chemistry; Corpus Striatum; Dihydroxyphenylala

1972
Biochemical and pharmacological aspects of Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 51

    Topics: Animals; Blood-Brain Barrier; Brain; Central Nervous System; Chemoreceptor Cells; Chlorpromazine; Co

1972
The conduct of initial drug studies in man.
    British medical bulletin, 1970, Volume: 26, Issue:3

    Topics: Animals; Clinical Trials as Topic; Dihydroxyphenylalanine; Disease Models, Animal; Drug Therapy; Dru

1970

Trials

2 trials available for dihydroxyphenylalanine and Disease Models, Animal

ArticleYear
    Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 2007, Aug-27, Volume: 119, Issue:34

    Topics: 3-Hydroxybutyric Acid; Acetazolamide; Acrylates; Administration, Intravenous; Adolescent; Adult; Aer

2007
The conduct of initial drug studies in man.
    British medical bulletin, 1970, Volume: 26, Issue:3

    Topics: Animals; Clinical Trials as Topic; Dihydroxyphenylalanine; Disease Models, Animal; Drug Therapy; Dru

1970

Other Studies

77 other studies available for dihydroxyphenylalanine and Disease Models, Animal

ArticleYear
Potential anti-arthritic and analgesic properties of essential oil and viridiflorol obtained from Allophylus edulis leaves in mice.
    Journal of ethnopharmacology, 2023, Jan-30, Volume: 301

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dexamethasone; Dihydroxyphenylalanine; D

2023
An Injectable Conductive Three-Dimensional Elastic Network by Tangled Surgical-Suture Spring for Heart Repair.
    ACS nano, 2019, 12-24, Volume: 13, Issue:12

    Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Survival; Dihydroxyphenylalanine; Disease Models,

2019
Regulation of Actg1 and Gsta2 is possible mechanism by which capsaicin alleviates apoptosis in cell model of 6-OHDA-induced Parkinson's disease.
    Bioscience reports, 2020, 06-26, Volume: 40, Issue:6

    Topics: Actins; Animals; Antiparkinson Agents; Apoptosis; Capsaicin; Cell Line, Tumor; Dihydroxyphenylalanin

2020
Exercise decreases aberrant corticostriatal plasticity in an animal model of l-DOPA-induced dyskinesia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2021, 04-01, Volume: 320, Issue:4

    Topics: Animals; Antiparkinson Agents; Benserazide; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine

2021
Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models.
    Cells, 2021, 07-21, Volume: 10, Issue:8

    Topics: Adenine; Animals; Animals, Genetically Modified; Antioxidants; Antiparkinson Agents; Astrocytes; Aut

2021
Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease.
    Nature communications, 2017, 04-03, Volume: 8

    Topics: Alzheimer Disease; Animals; Apoptosis; Cell Death; Dendritic Spines; Dihydroxyphenylalanine; Disease

2017
In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2017, 07-05, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents; Cholesterol; Colorectal Neoplasms; Dihydroxyphenylalanine; Disease M

2017
Tissue adhesive FK506-loaded polymeric nanoparticles for multi-layered nano-shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model.
    Biomaterials, 2018, Volume: 154

    Topics: Animals; Coated Materials, Biocompatible; Collagen; Diabetes Mellitus, Experimental; Dihydroxyphenyl

2018
Neuroprotective action and mechanistic evaluation of protodioscin against rat model of Parkinson's disease.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cell Line, Tumor; Cognition; Dihydroxyphenylalanine; Diosgenin; Di

2018
Synthesis and evaluation of
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Animals; Celecoxib; Cholangiocarcinoma; Cyclooxygenase 2; Dihydroxyphenylalanine; Disease Models, An

2018
Gutting the brain of inflammation: A key role of gut microbiome in human umbilical cord blood plasma therapy in Parkinson's disease model.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

    Topics: Animals; Brain; Cell Differentiation; Cytokines; Dihydroxyphenylalanine; Disease Models, Animal; Dop

2019
Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney.
    American journal of physiology. Renal physiology, 2013, Dec-15, Volume: 305, Issue:12

    Topics: Animals; Arachidonic Acid; Aromatic-L-Amino-Acid Decarboxylases; Catechol O-Methyltransferase; Cells

2013
The combination of oral L-DOPA/rimonabant for effective dyskinesia treatment and cytological preservation in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia.
    Behavioural pharmacology, 2013, Volume: 24, Issue:8

    Topics: Administration, Oral; Animals; Cannabinoid Receptor Antagonists; Corpus Striatum; Dihydroxyphenylala

2013
Potential efficacy of dopamine loaded-PVP/PAA nanogel in experimental models of Parkinsonism: possible disease modifying activity.
    Journal of biomedical materials research. Part A, 2015, Volume: 103, Issue:5

    Topics: Acrylic Resins; Animals; Catalepsy; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Male;

2015
Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2015, Volume: 23, Issue:5

    Topics: Animals; Behavior, Animal; Biomarkers; Cell Line; Corpus Striatum; Dependovirus; Dihydroxyphenylalan

2015
Fluorodopa is a Promising Fluorine-19 MRI Probe for Evaluating Striatal Dopaminergic Function in a Rat Model of Parkinson's Disease.
    Journal of neuroscience research, 2017, Volume: 95, Issue:7

    Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopaminergic Neu

2017
Comparative assessment of 6-[
    Journal of neurochemistry, 2017, Volume: 141, Issue:4

    Topics: Animals; Apomorphine; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Disease Models,

2017
D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD.
    Neurobiology of disease, 2010, Volume: 37, Issue:1

    Topics: Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Benzopyrans; Corpus Striatum; D

2010
Effect of 5-S-GAD on UV-B-induced cataracts in rats.
    Japanese journal of ophthalmology, 2009, Volume: 53, Issue:5

    Topics: Administration, Topical; Animals; Antioxidants; Cataract; Chromatography, High Pressure Liquid; Dihy

2009
Animal model of metastatic pheochromocytoma: evaluation by MRI and PET.
    Endocrine regulations, 2009, Volume: 43, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Female;

2009
Increased alpha-melanocyte-stimulating hormone (alpha-MSH) levels and melanocortin receptors expression associated with pigmentation in an NC/Nga mouse model of atopic dermatitis.
    Experimental dermatology, 2010, Volume: 19, Issue:2

    Topics: Adrenocorticotropic Hormone; Agouti Signaling Protein; Agouti-Related Protein; alpha-MSH; Animals; D

2010
Dopamine is not essential for the development of methamphetamine-induced neurotoxicity.
    Journal of neurochemistry, 2010, Volume: 114, Issue:4

    Topics: Adrenergic Agents; alpha-Methyltyrosine; Amphetamine-Related Disorders; Animals; Body Temperature; D

2010
Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dise

2011
Oil based nanocarrier system for transdermal delivery of ropinirole: a mechanistic, pharmacokinetic and biochemical investigation.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiparkinson Agents; Biological Availabil

2012
In-vivo measurement of LDOPA uptake, dopamine reserve and turnover in the rat brain using [18F]FDOPA PET.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:1

    Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Fluorine Radiois

2013
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catech

2013
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease.
    Synapse (New York, N.Y.), 2004, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Central

2004
Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Animals; Dihydroxyphenylalanine; Disease Models, Animal; Drug Interactions; Dyskinesias; Female; Par

2004
Age-dependent effects of severe traumatic brain injury on cerebral dopaminergic activity in newborn and juvenile pigs.
    Journal of neurotrauma, 2004, Volume: 21, Issue:8

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Brain Injuries;

2004
PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease.
    Experimental neurology, 2004, Volume: 189, Issue:2

    Topics: Animals; Binding, Competitive; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Female; Hum

2004
Dopamine overload visualized in the basal ganglia of rabbit brain during heatstroke can be suppressed by hypothermia.
    Neuroscience letters, 2005, Feb-28, Volume: 375, Issue:2

    Topics: Animals; Basal Ganglia; Blood Pressure; Body Temperature; Cerebellum; Dihydroxyphenylalanine; Diseas

2005
Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10.
    Brain research bulletin, 2006, Jun-15, Volume: 70, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coenzy

2006
Progressive changes of pre- and post-synaptic dopaminergic biomarkers in conscious MPTP-treated cynomolgus monkeys measured by positron emission tomography.
    Synapse (New York, N.Y.), 2007, Volume: 61, Issue:10

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Disease Models, Anim

2007
RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Dec-26, Volume: 27, Issue:52

    Topics: Analysis of Variance; Animals; Behavior, Animal; Corpus Striatum; Dihydroxyphenylalanine; Disease Mo

2007
[Heart function and the mechanisms of its regulation in modelling adaptation to hypoxia by 2,4-dinitrophenol administration].
    Kardiologiia, 1983, Volume: 23, Issue:1

    Topics: Adaptation, Physiological; Animals; Dihydroxyphenylalanine; Dinitrophenols; Disease Models, Animal;

1983
[Patholphysiological aspects of hyperbaric oxygenation exposure on the heart in compensatory hypertrophy].
    Kardiologiia, 1980, Volume: 20, Issue:7

    Topics: Acetylcholine; Animals; Cardiomegaly; Dihydroxyphenylalanine; Disease Models, Animal; Epinephrine; F

1980
The decarboxylation of DOPA in the parkinsonian brain: in vivo studies on an animal model.
    Journal of neural transmission. Supplementum, 1980, Issue:16

    Topics: Animals; Brain; Capillaries; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; Disease Model

1980
Concentrations of 3,4-dihydroxyphenylalanine and catecholamines and metabolites in brain in an anhepatic model of hepatic encephalopathy.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Catecholamines; Dihydroxyphenylalan

1995
Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzophenones; Carbidopa; Catec

1995
Biodistribution of anti-CEA F(ab')2 fragments conjugated with chelating polymers: influence of conjugate electron charge on tumor uptake and blood clearance.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Animals; Antibodies, Anti-Idiotypic; Binding Sites; Carcinoembryonic Antigen; Chelat

1993
Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: in vitro characterization and in vivo effects in the rat Parkinson model.
    Experimental neurology, 1996, Volume: 139, Issue:1

    Topics: Animals; Astrocytes; Cell Division; Cell Transplantation; Cells, Cultured; Cytomegalovirus; Dihydrox

1996
The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease.
    Journal of neuroscience methods, 1996, Volume: 67, Issue:2

    Topics: Animals; Carbidopa; Carbon Isotopes; Carrier Proteins; Cerebellum; Dihydroxyphenylalanine; Disease M

1996
In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase.
    Experimental neurology, 1998, Volume: 151, Issue:2

    Topics: 3T3 Cells; Animals; Antioxidants; Antiparkinson Agents; Apomorphine; Behavior, Animal; Biopterins; C

1998
Are reactive oxygen species involved in the pathogenesis of murine cerebral malaria?
    The Journal of infectious diseases, 1999, Volume: 179, Issue:1

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Female; Malaria, Cerebral; Membrane

1999
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
    Science (New York, N.Y.), 2000, Oct-27, Volume: 290, Issue:5492

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antigens, CD; Dihydroxyphenylalanine;

2000
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-01, Volume: 21, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Caspase 8; Caspase 9; Caspases; Di

2001
Novel observations with FDOPA-PET imaging after early nigrostriatal damage.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dise

2001
Delayed-amelanotic (DAM or Smyth) chicken: melanocyte dysfunction in vivo and in vitro.
    The Journal of investigative dermatology, 1986, Volume: 86, Issue:2

    Topics: Animals; Autoimmune Diseases; Cells, Cultured; Chick Embryo; Chickens; Dihydroxyphenylalanine; Disea

1986
Turnover of central biogenic amines in two-kidney, one-clip renal hypertensive rats.
    Neuroscience letters, 1986, Aug-29, Volume: 69, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Blood Pressure; Brain; Chromatography, High Pressure

1986
[Studies on the monoamine oxidase inhibiting properties of imidazole derivatives].
    Acta biologica et medica Germanica, 1973, Volume: 30, Issue:4

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Dose-Response Relationship, Drug; Dr

1973
Pharmacology of the central nervous system.
    Progress in neurology and psychiatry, 1971, Volume: 26

    Topics: Alcoholic Intoxication; Anesthetics; Animals; Anticonvulsants; Antidepressive Agents; Behavior; Cent

1971
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
    Journal of the neurological sciences, 1974, Volume: 22, Issue:3

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Diseas

1974
Enhancement of ampicillin efficacy by peroral levodopa in rat pyelonephritis.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1972, Nov-22, Volume: 11, Issue:22

    Topics: Administration, Oral; Ampicillin; Animals; Catechols; Cephalothin; Dihydroxyphenylalanine; Disease M

1972
The modification of L-dopa induced dyskinesias in the monkey by unilateral nigral lesions.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Animals; Caudate Nucleus; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Haplorhini; Hydr

1973
Experimental tremor following CNS lesions in monkeys.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Animals; Cerebellar Nuclei; Dihydroxyphenylalanine; Disease Models, Animal; Haplorhini; Mesencephalo

1973
Electrophysiological analysis of the effects of L-dopa on the reciprocal corticothalamic projections in the squirrel monkey. I. Iatrogenic coma and disinhibition of medial thalamic neurons.
    Journal of neural transmission, 1974, Volume: 35, Issue:2

    Topics: Animals; Carbidopa; Caudate Nucleus; Coma; Dihydroxyphenylalanine; Disease Models, Animal; Electric

1974
The incorporation of 51Cr-3, 4-dihydroxyphenylalanine (DOPA) complex into melanoma B 16.
    Zeitschrift fur Krebsforschung, 1970, Nov-20, Volume: 75, Issue:1

    Topics: Adrenal Glands; Animals; Chromium Isotopes; Dihydroxyphenylalanine; Disease Models, Animal; Kidney;

1970
Catecholamine, protein, and RNA content in advanced congestive heart failure in the Syrian hamster.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Animals; Cardiomegaly; Cricetinae; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Heart;

1972
Basic concepts underlying recent developments in the field of Parkinson's disease.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Biogenic Amines; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Humans; Parkinson Disease; P

1971
Biochemical aspects of experimentally induced parkinsonism.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Antiparkinson Agents; Apomorphine; Basal Ganglia;

1972
Some biochemical and behavioural correlates of a possible animal model of human hyperkinetic syndromes.
    Brain research, 1972, Dec-12, Volume: 47, Issue:2

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Catecholamines; Cats; Caudate Nucleus; Chlorpromaz

1972
Deserpidine antagonism by a tripeptide, L-prolyl-L-leucyglycinamide.
    Neuroendocrinology, 1973, Volume: 11, Issue:1

    Topics: Animals; Depression; Dihydroxyphenylalanine; Disease Models, Animal; Dose-Response Relationship, Dru

1973
Correlation between brain dopamine levels and 1-dopa activity in anti-Parkinson tests.
    European journal of pharmacology, 1973, Volume: 21, Issue:3

    Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Blepharoptosis; Brain;

1973
[The reserpine model of parkinsonism and changes in the metabolism of mediators].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Epinephrine; Male; Norepin

1973
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
    Clinical neurosurgery, 1973, Volume: 20

    Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan

1973
[Epidemic tremor in chickens as a model for the testing of antiparkinson drugs].
    Acta biologica et medica Germanica, 1973, Volume: 31, Issue:3

    Topics: Amantadine; Animals; Antiparkinson Agents; Chickens; Dihydroxyphenylalanine; Disease Models, Animal;

1973
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose

1974
Drug-induced relief of the tremor in monkeys with mesencephalic lesions.
    Nature, 1969, Oct-25, Volume: 224, Issue:5217

    Topics: Animals; Dihydroxyphenylalanine; Disease Models, Animal; Haplorhini; Mesencephalon; Tremor

1969
The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 63, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergi

1969
Drug-induced relief of experimental tremor in monkeys.
    Neurology, 1970, Volume: 20, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Brain Stem; Dihydroxyphenylalanine; Disease Models, Ani

1970
Production of involuntary movements by L-dopa in monkeys with tegmental lesions.
    Experimental neurology, 1971, Volume: 33, Issue:3

    Topics: Animals; Carboxy-Lyases; Dihydroxyphenylalanine; Disease Models, Animal; Haplorhini; Mesencephalon;

1971
Pharmacodynamic application of L-dopa in cardiogenic shock.
    American heart journal, 1972, Volume: 83, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Coronary Circulation; Dihydroxyphenylalanine; Disease Models, Animal

1972
Experimental midbrain lesions: neurochemical comparison between the animal model and Parkinson's disease.
    Brain research, 1971, Dec-24, Volume: 35, Issue:2

    Topics: Animals; Basal Ganglia; Carboxy-Lyases; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Dopami

1971
A model for rat paw edema. II. Analyses on the effect of the antagonists.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:3

    Topics: Amino Alcohols; Animals; Anti-Inflammatory Agents; Bradykinin; Bromelains; Carbamates; Carrageenan;

1970
[Experiences in the treatment of Parkinsonism with L-dopa. IV. Effects on the experimental extrapyranidal brady-akinesia in cats].
    Rivista di patologia nervosa e mentale, 1970, Volume: 91, Issue:1

    Topics: Animals; Cats; Caudate Nucleus; Dihydroxyphenylalanine; Disease Models, Animal; Extrapyramidal Tract

1970
Physiologic, biochemical, and pathological backgrounds of levodopa and possibilites for the future.
    Neurology, 1970, Volume: 20, Issue:12

    Topics: Animals; Basal Ganglia; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Forecasting; Human

1970
The effect of L-dopa on chronotropic responses to cardioaccelerator nerve stimulation in dogs.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:2

    Topics: Acidosis; Animals; Arteries; Blood Pressure; Dihydroxyphenylalanine; Disease Models, Animal; Dogs; E

1971