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dihydroxyphenylalanine and Depressive Disorder, Major

dihydroxyphenylalanine has been researched along with Depressive Disorder, Major in 4 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Howes, OD1
Williams, M1
Ibrahim, K1
Leung, G1
Egerton, A1
McGuire, PK1
Turkheimer, F1
Conway, CR1
Chibnall, JT1
Cumming, P1
Mintun, MA1
Gebara, MA1
Perantie, DC1
Price, JL1
Cornell, ME1
McConathy, JE1
Gangwani, S1
Sheline, YI1
Salazar, G1
Cuello, D1
Fragoso, M1
Benlloc, L1
TURNER, WJ1
MERLIS, S1

Trials

1 trial available for dihydroxyphenylalanine and Depressive Disorder, Major

ArticleYear
Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: a preliminary PET study.
    Psychiatry research, 2014, Mar-30, Volume: 221, Issue:3

    Topics: Adult; Animals; Antidepressive Agents; Aripiprazole; Caudate Nucleus; Citalopram; Corpus Striatum; D

2014

Other Studies

3 other studies available for dihydroxyphenylalanine and Depressive Disorder, Major

ArticleYear
Midbrain dopamine function in schizophrenia and depression: a post-mortem and positron emission tomographic imaging study.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 11

    Topics: Adult; Depressive Disorder, Major; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Humans

2013
Neuropsychiatric symptoms in Lewy body diffuse disease: a case report.
    Neurologia (Barcelona, Spain), 2011, Volume: 26, Issue:8

    Topics: Aged; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Dihydroxyphenylalanine

2011
A CLINICAL TRIAL OF PARGYLINE AND DOPA IN PSYCHOTIC SUBJECTS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Depression; Depressive Disorder, Majo

1964