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dihydroxyphenylalanine and Cystic Fibrosis

dihydroxyphenylalanine has been researched along with Cystic Fibrosis in 2 studies

Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Plasma and urine concentrations of the free amino acid 3,4-dihydroxyphenylalanine (dopa) were determined in a blind study in 16 children and adolescents with cystic fibrosis (CF), eight heterozygote parents of these children and in 11 healthy subjects who served as controls."7.68Abnormal 3,4-dihydroxyphenylalanine (dopa) concentrations in plasma and urine of patients with cystic fibrosis. ( Käser, H; Kraemer, R; Schöni, MH; Türler, K, 1990)
"Plasma and urine concentrations of the free amino acid 3,4-dihydroxyphenylalanine (dopa) were determined in a blind study in 16 children and adolescents with cystic fibrosis (CF), eight heterozygote parents of these children and in 11 healthy subjects who served as controls."3.68Abnormal 3,4-dihydroxyphenylalanine (dopa) concentrations in plasma and urine of patients with cystic fibrosis. ( Käser, H; Kraemer, R; Schöni, MH; Türler, K, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schöni, MH2
Türler, K2
Käser, H2
Kraemer, R2

Other Studies

2 other studies available for dihydroxyphenylalanine and Cystic Fibrosis

ArticleYear
Elevated dopa levels in cystic fibrosis.
    The New England journal of medicine, 1984, Nov-22, Volume: 311, Issue:21

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Dihydroxyphenylalanine; Humans

1984
Abnormal 3,4-dihydroxyphenylalanine (dopa) concentrations in plasma and urine of patients with cystic fibrosis.
    European journal of clinical investigation, 1990, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Child; Cystic Fibrosis; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; He

1990