dihydroxyphenylalanine has been researched along with Choreoathetosis Self-Mutilation Hyperuricemia Syndrome in 2 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fluorodopa F 18 ratio was significantly lower in the putamen (31 percent of control values), caudate nucleus (39 percent), frontal cortex (44 percent), and ventral tegmental complex (substantia nigra and ventral tegmentum; 57 percent) in the patients with Lesch-Nyhan disease than in the controls." | 1.29 | Presynaptic dopaminergic deficits in Lesch-Nyhan disease. ( Cohen, RM; Doudet, DJ; Ernst, M; Hankerson, JG; Hardy, K; Jons, PH; Matochik, JA; Pascualvaca, D; Zametkin, AJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ernst, M | 1 |
| Zametkin, AJ | 1 |
| Matochik, JA | 1 |
| Pascualvaca, D | 1 |
| Jons, PH | 1 |
| Hardy, K | 1 |
| Hankerson, JG | 1 |
| Doudet, DJ | 1 |
| Cohen, RM | 1 |
| Mizuno, TI | 1 |
| Yugari, Y | 1 |
1 trial available for dihydroxyphenylalanine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
Letter: Self mutilation in Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Administration, Oral; Child; Dihydroxyphenylalanine; Humans; Hydroxyindoleaceti | 1974 |
1 other study available for dihydroxyphenylalanine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
Presynaptic dopaminergic deficits in Lesch-Nyhan disease.
Topics: Adolescent; Adult; Analysis of Variance; Brain; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; C | 1996 |